Speed kills: cellular and molecular bases of methamphetamine‐induced nerve terminal degeneration and neuronal apoptosis
Abstract
Methamphetamine (METH) is a drug of abuse that has long been known to damage monoaminergic systems in the mammalian brain. Recent reports have provided conclusive evidence that METH can cause neuropathological changes in the rodent brain via apoptotic mechanisms akin to those reported in various models of neuronal death. The purpose of this review is to provide an interim account for a role of oxygen‐based radicals and the participation of transcription factors and the involvement of cell death genes in METH‐induced neurodegeneration. We discuss data suggesting the participation of endoplasmic reticulum and mitochondria‐mediated activation of caspase‐dependent and ‐independent cascades in the manifestation of METH‐induced apoptosis. Studies that use more comprehensive approaches to gene expression profiling should allow us to draw more instructive molecular portraits of the complex plastic and degenerative effects of this drug.—Cadet, J. L., Jayanthi, S., Deng, X. Speed kills: cellular and molecular bases of methamphetamine‐induced nerve terminal degeneration and neuronal apoptosis. FASEB J. 17, 1775–1788 (2003)
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Methamphetamine use, when regular, is associated with harms including injecting and sexual risk-taking behaviour, symptoms of mental ill health (psychosis, aggression, depression, anxiety), psychomotor, social and cognitive impairment, criminal activity, and sometimes death by overdose.
“Methamphetamine (MA) is a psychostimulant that when used regularly is associated with harms such as injecting and sexual risk-taking behaviour, symptoms of mental ill health (eg, psychosis, aggression, depression and/or anxiety), psychomotor, social and cognitive impairment, criminal activity and sometimes death caused by overdose.1–7”
Cites
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
Oltval, Z. N., Milliman, C. L., & Korsmeyer, S. J. (1993) · Cell · doi:10.1016/0092-8674(93)90509-o · Cited by 6,003 · see citing works
Death Receptors: Signaling and Modulation
Ashkenazi, A., & Dixit, V. M. (1998) · Science · doi:10.1126/science.281.5381.1305 · Cited by 5,866 · see citing works
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
Yang, J., Liu, X., Bhalla, K. N., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., & Wang, X. (1997) · Science · doi:10.1126/science.275.5303.1129 · Cited by 4,913 · see citing works
Caspases: the executioners of apoptosis
Cohen, G. M. (1997) · Biochemical Journal · doi:10.1042/bj3260001 · Cited by 4,720 · see citing works
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
Kluck, R. M., Bossy‐Wetzel, E., Green, D. R., & Newmeyer, D. D. (1997) · Science · doi:10.1126/science.275.5303.1132 · Cited by 4,715 · see citing works
Haine, M. M.-L., & Meeùs, N. (1986) · Cited by 3,463 · see citing works
Peroxynitrite oxidation of sulfhydryls.
Radí, R., Beckman, J. S., Bush, K., & Freeman, B. Α. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64313-7 · Cited by 2,499 · see citing works
Shimizu, S., Narita, M., Tsujimoto, Y., & Tsujimoto, Y. (1999) · Nature · doi:10.1038/20959 · Cited by 2,178 · see citing works
Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death
Yang, E., Zha, J., Jockel, J., Boise, L., Thompson, C. B., & Korsmeyer, S. J. (1995) · Cell · doi:10.1016/0092-8674(95)90411-5 · Cited by 2,101 · see citing works
Zinszner, H., Kuroda, M., Wang, X., Batchvarova, N., Lightfoot, R. T., Remotti, H. E., Stevens, J. L., & Ron, D. (1998) · Genes & Development · doi:10.1101/gad.12.7.982 · Cited by 1,996 · see citing works
McCullough, K. D., Martindale, J. L., Klotz, L., Aw, T. Y., & Holbrook, N. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.4.1249-1259.2001 · Cited by 1,895 · see citing works
Molecular basis of long-term plasticity underlying addiction
Nestler, E. J. (2001) · Nature reviews. Neuroscience · doi:10.1038/35053570 · Cited by 1,857 · see citing works
Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms
Dérijard, B., Raingeaud, J., Barrett, T., Wu, I.-H., Han, J., Ulevitch, R. J., & Davis, R. J. (1995) · Science · doi:10.1126/science.7839144 · Cited by 1,555 · see citing works
Organelle-specific initiation of cell death pathways
Ferri, K. F., & Kroemer, G. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-e255 · Cited by 1,455 · see citing works
Superoxide Anion Radical (O·̄2), Superoxide Dismutases, and Related Matters
Fridovich, I. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.30.18515 · Cited by 1,337 · see citing works
Role of poly(ADP-ribose) formation in DNA repair
Satoh, M. S., & Lindahl, T. L. (1992) · Nature · doi:10.1038/356356a0 · Cited by 1,181 · see citing works
Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis
Marzo, I., Brenner, C., Zamzami, N., Jürgensmeier, J. M., Susin, S. A., Vieira, H. L. A., Prévost, M.-C., Xie, Z., Matsuyama, S., Reed, J. C., et al. (1998) · Science · doi:10.1126/science.281.5385.2027 · Cited by 1,168 · see citing works
Cross-Talk between Two Cysteine Protease Families
Nakagawa, T., & Yuan, J. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.4.887 · Cited by 1,164 · see citing works
Ron, D., & Habener, J. F. (1992) · Genes & Development · doi:10.1101/gad.6.3.439 · Cited by 1,156 · see citing works
A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation
Schuman, E. M., & Madison, D. V. (1991) · Science · doi:10.1126/science.1720572 · Cited by 1,135 · see citing works
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.
Susín, S. A., Zamzami, N., Castedo, M., Hirsch, T., Marchetti, P., Macho, A., Daugas, É., Geuskens, M., & Kroemer, G. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.184.4.1331 · Cited by 1,133 · see citing works
Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
Dawson, V., Dawson, T., Bartley, D., Uhl, G. R., & Snyder, S. H. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-06-02651.1993 · Cited by 1,014 · see citing works
Association of Dopamine Transporter Reduction With Psychomotor Impairment in Methamphetamine Abusers
Volkow, N. D., Chang, L. L., Wang, G., Fowler, J. S., Leonido–Yee, M., Franceschi, D., Sedler, M. J., Gatley, S. J., HITZEMANN, R. J., Ding, Y. ‐., et al. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.377 · Cited by 984 · see citing works
Narita, M., Shimizu, S., Ito, T., Chittenden, T., Lutz, R. J., Matsuda, H., & Tsujimoto, Y. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14681 · Cited by 933 · see citing works
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.
Korsmeyer, S. J., Shutter, J. R., Novack, D. V., Merry, D. E., & Oltvai, Z. N. (1993) · PubMed · Cited by 865 · see citing works
Mitochondrial permeability transition is a central coordinating event of apoptosis.
Marchetti, P., Castedo, M., Susín, S. A., Zamzami, N., Hirsch, T., Macho, A., Haeffner, A., Hirsch, F., Geuskens, M., & Kroemer, G. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.184.3.1155 · Cited by 847 · see citing works
Patil, C., & Walter, P. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00219-2 · Cited by 779 · see citing works
Loss of Dopamine Transporters in Methamphetamine Abusers Recovers with Protracted Abstinence
Volkow, N. D., Chang, L. L., Wang, G., Fowler, J. S., Franceschi, D., Sedler, M. J., Gatley, S. J., Miller, E. N., HITZEMANN, R. J., Ding, Y., et al. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-23-09414.2001 · Cited by 754 · see citing works
Karin, M., & Hunter, T. R. (1995) · Current Biology · doi:10.1016/s0960-9822(95)00151-5 · Cited by 752 · see citing works
Striatal dopamine nerve terminal markers in human, chronic methamphetamine users
Wilson, J. M., Kalasinsky, K. S., Levey, A. I., Bergeron, C., Reiber, G. D., Anthony, R. M., Schmunk, G. A., Shannak, K. S., Haycock, J. W., & Kish, S. J. (1996) · Nature Medicine · doi:10.1038/nm0696-699 · Cited by 718 · see citing works
Psychomotor stimulant addiction: a neural systems perspective
Everitt, B. J., & Wolf, M. E. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03312.2002 · Cited by 700 · see citing works
Sulzer, D., Chen, T., Lau, Y., Kristensen, H., Rayport, S., & Ewing, A. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-05-04102.1995 · Cited by 688 · see citing works
Marzo, I., Brenner, C., Zamzami, N., Susín, S. A., Beutner, G., Brdiczka, D. G., Rémy, R., Xie, Z.-H., Reed, J. C., & Kroemer, G. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.8.1261 · Cited by 684 · see citing works
Pleiotropic effects of a null mutation in the c-fos proto-oncogene
Johnson, R. S., Spiegelman, B. M., & Papaioannou, V. E. (1992) · Cell · doi:10.1016/0092-8674(92)90592-z · Cited by 630 · see citing works
Mechanisms of Amphetamine Action Revealed in Mice Lacking the Dopamine Transporter
Jones, S. R., Gainetdinov, R. R., Wightman, R. M., & Caron, M. G. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-06-01979.1998 · Cited by 626 · see citing works
McCann, U. D., Wong, D. F., Yokoi, F., Villemagne, V., Dannals, R. F., & Ricaurte, G. A. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-20-08417.1998 · Cited by 602 · see citing works
The chemistry of DNA damage from nitric oxide and peroxynitrite
Burney, S., Caulfield, J. L., Niles, J. C., Wishnok, J. S., & Tannenbaum, S. R. (1999) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(99)00006-8 · Cited by 548 · see citing works
Davidson, C., Gow, A. J., Lee, T. H., & Ellinwood, E. H. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00054-6 · Cited by 521 · see citing works
Invited Review Free radicals and the pathobiology of brain dopamine systems
Cadet, J. L., & Brannock, C. (1998) · Neurochemistry International · doi:10.1016/s0197-0186(97)00031-4 · Cited by 499 · see citing works
Self-citationRicaurte, G. A., Schuster, C. R., & Seiden, L. S. (1980) · Brain Research · doi:10.1016/0006-8993(80)90952-x · Cited by 490 · see citing works
Jänicke, R. U., Ng, P., Sprengart, M. L., & Porter, A. G. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.25.15540 · Cited by 486 · see citing works
Mitochondria, the killer organelles and their weapons
Ravagnan, L., Roumier, T., & Kroemer, G. (2002) · Journal of Cellular Physiology · doi:10.1002/jcp.10111 · Cited by 484 · see citing works
Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain
Ricaurte, G. A., Guillery, R. W., Seiden, L. S., Schuster, C. R., & Moore, R. Y. (1982) · Brain Research · doi:10.1016/0006-8993(82)90198-6 · Cited by 479 · see citing works
Minden, A., Lin, A., Smeal, T., Dérijard, B., Cobb, M. H., Davis, R. J., & Karin, M. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.10.6683 · Cited by 467 · see citing works
The double-edged role of nitric oxide in brain function and superoxide-mediated injury.
Beckman, J. S. (1991) · PubMed · Cited by 463 · see citing works
LaVoie, M. J., & Hastings, T. G. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-04-01484.1999 · Cited by 449 · see citing works
Cubells, J. F., Rayport, S., Rajendran, G., & Sulzer, D. L. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-04-02260.1994 · Cited by 448 · see citing works
Sonders, M. S., Zhu, S.-J., Zahniser, N. R., Kavanaugh, M. P., & Amara, S. G. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-03-00960.1997 · Cited by 446 · see citing works
Hotchkiss, A. J., & Gibb, J. W. (1980) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)32165-8 · Cited by 443 · see citing works
Boyd, J. M., Gallo, G. J., Elangovan, B., Houghton, A. B., Malstrom, S. E., Avery, B. J., Ebb, R. G., Subramanian, T., Chittenden, T., & Lutz, R. J. (1995) · PubMed · Cited by 429 · see citing works
Further studies of the role of hyperthermia in methamphetamine neurotoxicity.
Bowyer, J. F., Davies, D. L., Schmued, L. C., Broening, H. W., Newport, G. D., Slikker, W., & Holson, R. R. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38650-7 · Cited by 412 · see citing works
Ramana, C. V., Boldogh, I. R., Izumi, T., & MITRA, S. P. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.9.5061 · Cited by 409 · see citing works
Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse.
O'Callaghan, J. P., & Miller, D. B. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22433-8 · Cited by 409 · see citing works
Massaro, E. J. (2002) · Humana Press eBooks · doi:10.1007/978-1-59259-132-9 · Cited by 405 · see citing works
Mogi, M., Togari, A., Kondo, T., Mizuno, Y., Komure, O., Kuno, S., Ichinose, H., & Nagatsu, T. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00463-2 · Cited by 394 · see citing works
Superoxide Reacts with Nitric Oxide to Nitrate Tyrosine at Physiological pH via Peroxynitrite
Reiter, C. D., Teng, R., & Beckman, J. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m910433199 · Cited by 385 · see citing works
Serotonin content of the brain stem nuclei in the rat
Palkovits, M., Brownstein, M., & Saavedra, J. M. (1974) · Brain Research · doi:10.1016/0006-8993(74)90688-x · Cited by 384 · see citing works
Gu, H., Wall, S. C., & Rudnick, G. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37256-3 · Cited by 379 · see citing works
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH 2 -terminal kinase
Tournier, C., Whitmarsh, A. J., Cavanagh, J., Barrett, T., & Davis, R. J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7337 · Cited by 377 · see citing works
Murachi, T., Tanaka, K., Hatanaka, M., & Murakami, T. (1981) · Advances in Enzyme Regulation · doi:10.1016/0065-2571(81)90026-1 · Cited by 374 · see citing works
Evidence for long-term neurotoxicity associated with methamphetamine abuse
Ernst, T., Chang, L., Leonido–Yee, M., & Speck, O. (2000) · Neurology · doi:10.1212/wnl.54.6.1344 · Cited by 373 · see citing works
Watson, A., Eilers, A., Lallemand, D., Kyriakis, J. M., Rubin, L. L., & Ham, J. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-02-00751.1998 · Cited by 360 · see citing works
Growth factors regulate the survival and fate of cells derived from human neurospheres
Caldwell, M. A., He, X., Wilkie, N. M., Pollack, S., Marshall, G. R., Wafford, K. A., & Svendsen, C. N. (2001) · Nature Biotechnology · doi:10.1038/88158 · Cited by 343 · see citing works
Herdegen, T., Claret, F.-X., Kallunki, T., Martín-Villalba, A., Winter, C., Hunter, T., & Karin, M. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-14-05124.1998 · Cited by 327 · see citing works
Cognitive Impairment in Individuals Currently Using Methamphetamine
Simon, S. L., Domier, C. P., Carnell, J., Brethen, P., Rawson, R. A., & Ling, W. W. (2000) · American Journal on Addictions · doi:10.1080/10550490050148053 · Cited by 322 · see citing works
Bax and Bak Promote Apoptosis by Modulating Endoplasmic Reticular and Mitochondrial Ca2+ Stores
Nutt, L. K., Pataer, A., Pahler, J. C., Fang, B., Roth, J. A., McConkey, D. J., & Swisher, S. G. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106817200 · Cited by 320 · see citing works
Amphetamine abuse. Pattern and effects of high doses taken intravenously
Kramer, J. C. (1967) · JAMA · doi:10.1001/jama.201.5.305 · Cited by 313 · see citing works
Bad Is a BH3 Domain-Containing Protein That Forms an Inactivating Dimer with Bcl-X L
Kelekar, A., Chang, B. S., Harlan, J. E., Fesik, S. W., & Thompson, C. B. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.12.7040 · Cited by 273 · see citing works
Methamphetamine-induced neuronal damage: A possible role for free radicals
Vito, M. J. D., & Wagner, G. C. (1989) · Neuropharmacology · doi:10.1016/0028-3908(89)90130-5 · Cited by 270 · see citing works
Fumagalli, F., Gainetdinov, R. R., Valenzano, K. J., & Caron, M. G. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-13-04861.1998 · Cited by 266 · see citing works
Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species
Yoshizumi, M., Abe, J., Haendeler, J., Huang, Q., & Berk, B. C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.16.11706 · Cited by 263 · see citing works
Cadet, J. L., Sheng, P., All, S., Rothman, R. B., Carlson, E. J., & Epstein, C. J. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62010380.x · Cited by 263 · see citing works
Self-citationMiller, D. B., & O'Callaghan, J. P. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22434-x · Cited by 261 · see citing works
Albers, D. S., & Sonsalla, P. K. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12160-5 · Cited by 258 · see citing works
Fukunaga, K., & Miyamoto, E. (1998) · Molecular Neurobiology · doi:10.1007/bf02740604 · Cited by 256 · see citing works
A novel SAPK/JNK kinase, MKK7, stimulated by TNFα and cellular stresses
Moriguchi, T., Toyoshima, F., Masuyama, N., Hanafusa, H., Gotoh, Y., & Nishida, E. (1997) · The EMBO Journal · doi:10.1093/emboj/16.23.7045 · Cited by 250 · see citing works
Higher Cortical and Lower Subcortical Metabolism in Detoxified Methamphetamine Abusers
Volkow, N. D., Chang, L., Wang, G., Fowler, J. S., Franceschi, D., Sedler, M. J., Gatley, S. J., Hitzemann, R., Ding, Y., Wong, C., et al. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.383 · Cited by 249 · see citing works
Fumagalli, F., Gainetdinov, R. R., Wang, Y., Valenzano, K. J., Miller, G. W., & Caron, M. G. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-07-02424.1999 · Cited by 241 · see citing works
Rapid and Reversible Effects of Methamphetamine on Dopamine Transporters
Fleckenstein, A. E., Metzger, R. R., Wilkins, D. G., Gibb, J. W., & Hanson, G. R. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36858-2 · Cited by 233 · see citing works
Nucleotide excision repair: From E. coli to man
Petit, C. R., & Sancar, A. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80034-0 · Cited by 230 · see citing works
Excitotoxicity, free radicals, and cell membrane changes
Dugan, L. L., & Choi, D. W. (1994) · Annals of Neurology · doi:10.1002/ana.410350707 · Cited by 226 · see citing works
Seiden, L. S., & Vosmer, G. (1984) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(84)90125-4 · Cited by 221 · see citing works
Kogan, F. J., Nichols, W. K., & Gibb, J. W. (1976) · European Journal of Pharmacology · doi:10.1016/0014-2999(76)90090-x · Cited by 217 · see citing works
Villemagne, V. L., Yuan, J., Wong, D. F., Dannals, R. F., Hatzidimitriou, G., Mathews, W. B., Ravert, H. T., Musachio, J. L., McCann, U. D., & Ricaurte, G. A. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00419.1998 · Cited by 211 · see citing works
Deng, X.-L., Wang, Y., Chou, J., & Cadet, J. (2001) · Brain Research. Molecular Brain Research · doi:10.1016/s0169-328x(01)00184-x · Cited by 208 · see citing works
Self-citationMashima, T., Naito, M., & Tsuruo, T. (1999) · Oncogene · doi:10.1038/sj.onc.1202558 · Cited by 208 · see citing works
Long-term effects of chronic methamphetamine administration in rhesus monkeys
Woolverton, W. L., Ricaurte, G. A., Forno, L. S., & Seiden, L. S. (1989) · Brain Research · doi:10.1016/0006-8993(89)91279-1 · Cited by 205 · see citing works
Giovanni, A., Liang, L., Hastings, T. G., & Zigmond, M. J. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64041819.x · Cited by 202 · see citing works
Fos is an essential component of the mammalian UV response.
Schreiber, M., Baumann, B., Cotten, M. L., Angel, P. E., & Wagner, E. F. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb00218.x · Cited by 196 · see citing works
Base excision repair in a network of defence and tolerance
Nilsen, H. L., & Krokan, H. E. (2001) · Carcinogenesis · doi:10.1093/carcin/22.7.987 · Cited by 196 · see citing works
Roles of Reactive Oxygen Species: Signaling and Regulation of Cellular Functions
Gamaley, I. A., & Klyubin, I. V. (1999) · International review of cytology · doi:10.1016/s0074-7696(08)61568-5 · Cited by 193 · see citing works
Sonsalla, P. K., Riordan, D. E., & Heikkila, R. E. (1990) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22956-1 · Cited by 184 · see citing works
Amphetamines induce apoptosis and regulation of bcl‐x splice variants in neocortical neurons
Stumm, G., Schlegel, J., Schäfer, T., Würz, C., Mennel, H. D., Krieg, J. C., & Vedder, H. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.9.1065 · Cited by 178 · see citing works
Tabner, B. S. P. B. J., Turnbull, B. S. P. S., El-Agnaf, B. S. P. O. M. A., & Allsop, B. S. P. D. (2001) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026013394822 · Cited by 174 · see citing works
Mechanisms controlling cellular suicide: role of Bcl-2 and caspases
Allen, R. T., Cluck, M. W., & Agrawal, D. K. (1998) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050171 · Cited by 166 · see citing works
Jayanthi, S., Deng, X., BORDELON, M., McCoy, M. T., & Cadet, J. L. (2001) · The FASEB Journal · doi:10.1096/fj.01-0025com · Cited by 165 · see citing works
Self-citationMethamphetamine-related stroke: four cases
Perez, J. A., Arsura, E. L., & Strategos, S. (1999) · Journal of Emergency Medicine · doi:10.1016/s0736-4679(99)00009-8 · Cited by 162 · see citing works
Bokemeyer, D., Sorokin, A., Yan, M., Ahn, N. G., Templeton, D. J., & Dunn, M. J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.2.639 · Cited by 157 · see citing works
Localization of pontine PGO wave generation sites and their anatomical projections in the rat
Datta, S., Siwek, D. F., Patterson, E. H., & Cipolloni, P. B. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199812)30:4 · Cited by 156 · see citing works
Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.
Fornace, A. J., Zmudzka, B. Z., Hollander, M. C., & Wilson, S. H. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.2.851 · Cited by 155 · see citing works
Kinetics and Block of Dopamine Uptake in Synaptosomes from Rat Caudate Nucleus
Krueger, B. K. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb08847.x · Cited by 155 · see citing works
Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules
Utz, P. J., & Anderson, P. (2000) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400696 · Cited by 155 · see citing works
Amphetamine toxicity: Experience with 127 cases
Derlet, R. W., Rice, P., Horowitz, B. Z., & Lord, R. V. (1989) · Journal of Emergency Medicine · doi:10.1016/0736-4679(89)90263-1 · Cited by 153 · see citing works
Gluck, M. R., Moy, L. Y., Jayatilleke, E., Hogan, K. A., Manzino, L., & Sonsalla, P. K. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00549.x · Cited by 152 · see citing works
Paschen, W. (2001) · Cell Calcium · doi:10.1054/ceca.2000.0162 · Cited by 150 · see citing works
Sonsalla, P. K., Gibb, J. W., & Hanson, G. R. (1986) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)24344-0 · Cited by 147 · see citing works
Itzhak, Y., Gandia, C. E., Huang, P. L., & Ali, S. F. (1998) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37339-2 · Cited by 147 · see citing works
Psychological morbidity and route of administration among amphetamine users in Sydney, Australia
Hall, W., Hando, J., Darke, S. G., & Ross, J. E. (1996) · Addiction · doi:10.1046/j.1360-0443.1996.9118110.x · Cited by 146 · see citing works
Jayanthi, S., Ladenheim, B., & Cadet, J. L. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb08224.x · Cited by 143 · see citing works
Self-citationMICHEL, R., & Adams, A. P. (1979) · Anaesthesia · doi:10.1111/j.1365-2044.1979.tb06250.x · Cited by 142 · see citing works
Chan, P., Monte, D. A. D., Luo, J. J., DeLanney, L. E., Irwin, I., & Langston, J. W. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62062484.x · Cited by 141 · see citing works
Friedman, S. D., Castañeda, E., & Hodge, G. K. (1998) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(98)00066-5 · Cited by 136 · see citing works
Amphetamine induces depletion of dopamine and loss of dopamine uptake sites in caudate
Wagner, C., Ricaurte, G. A., Johanson, C. E., Schuster, C. R., & Seiden, L. S. (1980) · Neurology · doi:10.1212/wnl.30.5.547 · Cited by 134 · see citing works
Fleckenstein, A. E., Haughey, H. M., Metzger, R. R., Kokoshka, J. M., Riddle, E. L., Hanson, J. E., Gibb, J. W., & Hanson, G. R. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00588-9 · Cited by 134 · see citing works
Methamphetamine exposure can produce neuronal degeneration in mouse hippocampal remnants
Schmued, L. C., & Bowyer, J. F. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00173-x · Cited by 131 · see citing works
Traffic at the intersection of neurotrophic factor signaling and neurodegeneration
Salehi, A., Delcroix, J.-D., & Mobley, W. C. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)00038-3 · Cited by 131 · see citing works
Death in amphetamine users: causes and rates.
Kalant, H., & Kalant, O. J. (1975) · PubMed · Cited by 128 · see citing works
Harvey, D. C., Laćan, G., Tanious, S. P., & Melega, W. P. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02439-2 · Cited by 127 · see citing works
Neurotoxic Amphetamine Analogues: Effects in Monkeys and Implications for Humansa
Ricaurte, G. A., & McCann, U. D. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb24586.x · Cited by 126 · see citing works
Marek, G. J., Vosmer, G., & Seiden, L. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90467-p · Cited by 126 · see citing works
Melega, W. P., Raleigh, M. J., Stout, D. B., Laćan, G., Huang, S.-C., & Phelps, M. E. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00548-9 · Cited by 126 · see citing works
Jicha, G. A., Berenfeld, B., & Davies, P. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990315)55:6 · Cited by 123 · see citing works
Deng, X., Cai, N.-S., McCoy, M. T., Chen, W., Trush, M. A., & Cadet, J. L. (2002) · Neuropharmacology · doi:10.1016/s0028-3908(02)00034-5 · Cited by 122 · see citing works
Self-citationUjike, H., Takaki, M., Kodama, M., & Kuroda, S. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04151.x · Cited by 121 · see citing works
Pu, C., & Vorhees, C. V. (1993) · Developmental Brain Research · doi:10.1016/0165-3806(93)90201-k · Cited by 119 · see citing works
Hirata, H., Ladenheim, B., Carlson, E. J., Epstein, C. J., & Cadet, J. L. (1996) · Brain Research · doi:10.1016/0006-8993(95)01502-7 · Cited by 117 · see citing works
Self-citationImam, S. Z., Newport, G. D., Itzhak, Y., Cadet, J. L., Islam, F., Slikker, W., & Ali, S. F. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00029.x · Cited by 113 · see citing works
Self-citationNull Mutation of c-fos Causes Exacerbation of Methamphetamine-Induced Neurotoxicity
Deng, X., Ladenheim, B., Tsao, L.-I., & Cadet, J. L. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-22-10107.1999 · Cited by 113 · see citing works
Self-citationFukumura, M., Cappon, G. D., Pu, C., Broening, H. W., & Vorhees, C. V. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00656-8 · Cited by 110 · see citing works
Farfel, G. M., & Seiden, L. S. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)24505-0 · Cited by 109 · see citing works
Gervais, J., & Rouillard, C. (2000) · Synapse · doi:10.1002/(sici)1098-2396(20000315)35:4 · Cited by 109 · see citing works
Long-Term Changes in Basal Ganglia Function after a Neurotoxic Regimen of Methamphetamine
Chapman, D. E., Hanson, G. R., Kesner, R. P., & Keefe, K. A. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38769-5 · Cited by 109 · see citing works
Frey, K. A., Kilbourn, M. R., & Robinson, T. E. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(97)01152-7 · Cited by 104 · see citing works
Cadet, J. L., Jayanthi, S., McCoy, M. T., Vawter, M. P., & Ladenheim, B. (2001) · Synapse · doi:10.1002/syn.1058 · Cited by 103 · see citing works
Self-citationFrechilla, D., Cobreros, A., Saldise, L., Moratalla, R., Insausti, R., Luquín, M. R., & R�o, J. D. (2001) · Synapse · doi:10.1002/1098-2396(20010315)39:4 · Cited by 103 · see citing works
Self-citationNature of methamphetamine-induced rapid and reversible changes in dopamine transporters
Kokoshka, J. M., Vaughan, R. A., Hanson, G. R., & Fleckenstein, A. E. (1998) · European Journal of Pharmacology · doi:10.1016/s0014-2999(98)00741-9 · Cited by 102 · see citing works
Koch, R., & Barish, M. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-05-02585.1994 · Cited by 101 · see citing works
Figueredo-Cardenas, G., Harris, C. L., Anderson, K. D., & Reiner, A. J. (1998) · Experimental Neurology · doi:10.1006/exnr.1997.6724 · Cited by 100 · see citing works
Immunocytochemical evidence for methamphetamine‐induced serotonergic axon loss in the rat brain
Axt, K. J., & Molliver, M. E. (1991) · Synapse · doi:10.1002/syn.890090405 · Cited by 100 · see citing works
Mechanisms of Bcl-2 family protein function and dysfunction in health and disease.
Reed, J. C. (1996) · PubMed · Cited by 99 · see citing works
Cass, W. A. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-24-08132.1996 · Cited by 99 · see citing works
Cass, W. A., & Manning, M. W. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-17-07653.1999 · Cited by 98 · see citing works
Yui, K., Goto, K., Ikemoto, S., Ishiguro, T., Angrist, B., Duncan, G. E., Sheitman, B., Lieberman, J. A., Bracha, S., & Ali, S. F. (1999) · Molecular Psychiatry · doi:10.1038/sj.mp.4000575 · Cited by 95 · see citing works
Steranka, L. R., & Sanders‐Bush, E. (1980) · European Journal of Pharmacology · doi:10.1016/0014-2999(80)90351-9 · Cited by 95 · see citing works
Bakhit, C., Morgan, M. E., Peat, M., & Gibb, J. W. (1981) · Neuropharmacology · doi:10.1016/0028-3908(81)90053-8 · Cited by 94 · see citing works
Dopamine-glutamate interactions in methamphetaminc-induced neurotoxicity
Marshall, J. F., O'Dell, S. J., & Weihmuller, F. B. (1993) · Journal of Neural Transmission · doi:10.1007/bf01245234 · Cited by 93 · see citing works
Clinical manifestations and prognostic features of acute methamphetamine intoxication.
Lan, K. C., Lin, Y., Yu, F. C., Lin, C. S., & Chu, P. (1998) · PubMed · Cited by 91 · see citing works
Deng, X., & Cadet, J. L. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00169-8 · Cited by 90 · see citing works
Self-citationJayanthi, S., Ladenheim, B., Andrews, A. M., & Cadet, J. L. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00698-8 · Cited by 90 · see citing works
Self-citationExpression of D1 receptor mRNA in projections from the forebrain to the ventral tegmental area
Lu, X., Churchill, L., & Kalivas, P. W. (1997) · Synapse · doi:10.1002/(sici)1098-2396(199702)25:2 · Cited by 88 · see citing works
Self-citationSonsalla, P. K., & Heikkila, R. E. (1988) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(88)90054-1 · Cited by 86 · see citing works
Protein Phosphorylation Cascades Associated with Methamphetamine‐induced Glial Activation
Hebert, M. A., & O'Callaghan, J. P. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05200.x · Cited by 84 · see citing works
Fleckenstein, A. E., Wilkins, D. G., Gibb, J. W., & Hanson, G. R. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37016-8 · Cited by 84 · see citing works
Vega, W. A., Gil, A. G., Warheit, G. J., Apospori, E., & Zimmerman, R. S. (1993) · Suicide and Life-Threatening Behavior · doi:10.1111/j.1943-278x.1993.tb00375.x · Cited by 84 · see citing works
Fetal and Infant Deaths Associated with Maternal Methamphetamine Abuse
Stewart, J. L., & Meeker, J. E. (1997) · Journal of Analytical Toxicology · doi:10.1093/jat/21.6.515 · Cited by 82 · see citing works
Pretreatment with ascorbic acid attenuates the neurotoxic effects of methamphetamine in rats.
Wagner, G. C., Carelli, R. M., & Jarvis, M. F. (1985) · PubMed · Cited by 80 · see citing works
Kaina, B., Haas, S., & Kappes, H. (1997) · PubMed · Cited by 75 · see citing works
Cappon, G. D., Pu, C., & Vorhees, C. V. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02107-7 · Cited by 74 · see citing works
Age‐Dependent Differential Responses of Monoaminergic Systems to High Doses of Methamphetamine
Kokoshka, J. M., Fleckenstein, A. E., Wilkins, D. G., & Hanson, G. R. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0752095.x · Cited by 73 · see citing works
Imam, S. Z., & Ali, S. F. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00477.x · Cited by 68 · see citing works
Baldwin, H. A., Colado, M. I., Murray, T. K., Souza, R. J. D., & Green, A. R. (1993) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1993.tb12847.x · Cited by 67 · see citing works
Intracerebral haemorrhage and vasculitis secondary to amphetamine use
Salanova, V., & Taubner, R. (1984) · Postgraduate Medical Journal · doi:10.1136/pgmj.60.704.429 · Cited by 65 · see citing works
Jayanthi, S., McCoy, M. T., Ladenheim, B., & Cadet, J. L. (2002) · Molecular Pharmacology · doi:10.1124/mol.61.5.1124 · Cited by 65 · see citing works
Self-citationItzhak, Y., Martin, J. L., & Ali, S. F. (2000) · Neuroreport · doi:10.1097/00001756-200009110-00022 · Cited by 64 · see citing works
Methamphetamine treatment rapidly inhibits serotonin, but not glutamate, transporters in rat brain
Kokoshka, J. M., Metzger, R. R., Wilkins, D. G., Gibb, J. W., Hanson, G. R., & Fleckenstein, A. E. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00472-7 · Cited by 62 · see citing works
Involvement of ICE family proteases in apoptosis induced by reoxygenation of hypoxic hepatocytes
Shimizu, S., Eguchi, Y., Kamiike, W., Akao, Y., Kosaka, H., Hasegawa, J., Matsuda, H., & Tsujimoto, Y. (1996) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1996.271.6.g949 · Cited by 61 · see citing works
Amphetamines: An Update on Forensic Issues
Logan, B. K. (2001) · Journal of Analytical Toxicology · doi:10.1093/jat/25.5.400 · Cited by 60 · see citing works
Ricaurte, G. A., Fuller, R. W., Perry, K. W., Seiden, L. S., & Schuster, C. R. (1983) · Neuropharmacology · doi:10.1016/0028-3908(83)90075-8 · Cited by 59 · see citing works
Kirksey, D. F., & Slotkin, T. A. (1979) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1979.tb08692.x · Cited by 59 · see citing works
Takaki, M., Ujike, H., Kodama, M., Takehisa, Y., Nakata, K., & Kuroda, S. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00615.x · Cited by 57 · see citing works
Cadet, J. L., Ali, S. F., & EPSTEIN, C. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb21827.x · Cited by 57 · see citing works
Self-citationLackinger, D. (2001) · Mutagenesis · doi:10.1093/mutage/16.3.233 · Cited by 57 · see citing works
Nakayama, M., Koyama, T., & Yamashita, I. (1993) · Brain Research · doi:10.1016/0006-8993(93)91712-2 · Cited by 55 · see citing works
Sullivan, A. M., Opacka‐Juffry, J., Hötten, G., Pohl, J., & Blunt, S. B. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00623-x · Cited by 54 · see citing works
Wędzony, K., Maćkowiak, M., Fijał, K., & Gołembiowska, K. (1996) · Synapse · doi:10.1002/(sici)1098-2396(199611)24:3 · Cited by 53 · see citing works
Self-citationNitric Oxide Is a Mediator of Methamphetamine (METH)‐Induced Neurotoxicity
SHENG, P., Cerruti, C., Ali, S. F., & Cadet, J. L. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb17440.x · Cited by 53 · see citing works
Self-citationSawada, H., Kawamura, T., Shimohama, S., AKAIKE, A., & Kimura, J. (1996) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19960215)43:4 · Cited by 52 · see citing works
Mice with Partial Deficiency of c-Jun Show Attenuation of Methamphetamine-Induced Neuronal Apoptosis
Deng, X., Jayanthi, S., Ladenheim, B., Krasnova, I. N., & Cadet, J. L. (2002) · Molecular Pharmacology · doi:10.1124/mol.62.5.993 · Cited by 50 · see citing works
Self-citationMethamphetamine-induced dopaminergic neurotoxicity in mice
Itzhak, Y., Martin, J. L., & Ali, S. F. (2002) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(02)00257-9 · Cited by 46 · see citing works
Marek, G. J., Vosmer, G., & Seiden, L. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90889-j · Cited by 44 · see citing works
Sánchez, V., Zeini, M., Camarero, J., O’Shea, E., Boscá, L., Green, A. R., & Colado, M. I. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01714.x · Cited by 39 · see citing works
Cadet, J. L., McCoy, M. T., & Ladenheim, B. (2002) · Synapse · doi:10.1002/syn.10074 · Cited by 38 · see citing works
Self-citationItzhak, Y., & Ali, S. F. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04156.x · Cited by 38 · see citing works
Hirata, H., Asanuma, M., & Cadet, J. L. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00055-2 · Cited by 37 · see citing works
Self-citationCallahan, B. T., Cord, B. J., Yuan, J., McCann, U. D., & Ricaurte, G. A. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00341.x · Cited by 36 · see citing works
Miller, D. B., O'Callaghan, J. P., & Ali, S. F. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05196.x · Cited by 36 · see citing works
Sarnyai, Z., McKittrick, C. R., McEwen, B. S., & Kreek, M. J. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199811)30:3 · Cited by 35 · see citing works
Teuchert‐Noodt, G., & Dawirs, R. R. (1991) · Neuropharmacology · doi:10.1016/0028-3908(91)90181-a · Cited by 33 · see citing works
Late induction of human DNA ligase I after UV-C irradiation
Montecucco, A., Savini, E., Biamonti, G., Stefanini, M., Focher, F., & Ciarrocchi, G. (1995) · Nucleic Acids Research · doi:10.1093/nar/23.6.962 · Cited by 33 · see citing works
Sonsalla, P. K., Gibb, J. W., & Hanson, G. R. (1986) · Neuropharmacology · doi:10.1016/0028-3908(86)90139-5 · Cited by 32 · see citing works
Drugs of Abuse and Alcohol in Weekend Drivers Involved in Car Crashes in Belgium
Schepens, P., Pauwels, A., Damme, P. V., Musuku, A., Beaucourt, L., & Selala, M. I. (1998) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(98)70210-0 · Cited by 30 · see citing works
Intracerebral hemorrhage and angiographic beading following amphetamine abuse
Conci, F., D’Angelo, V., Tampieri, D. I., & Vecchi, G. L. (1988) · Neurological Sciences · doi:10.1007/bf02334412 · Cited by 27 · see citing works
Direct interactions of methamphetamine with the nucleus
Asanuma, M., Hayashi, T., Ordonez, S., Ogawa, N., & Cadet, J. L. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00128-5 · Cited by 26 · see citing works
Self-citationIncreased dopamine metabolism in the rat neostriatum after toxic doses of d-methylamphetamine
Ricaurte, G. A. (1983) · Neuropharmacology · doi:10.1016/0028-3908(83)90228-9 · Cited by 26 · see citing works
Illicit Methamphetamine: Analysis, Synthesis, and Availability
Puder, K. S., Kagan, D. V., & Morgan, J. P. (1988) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952998809001564 · Cited by 23 · see citing works
Fukui, K., Nakajima, T., Kariyama, H., Kashiba, A., Kato, N., Tohyama, I., & Kimura, H. (1989) · Brain Research · doi:10.1016/0006-8993(89)90562-3 · Cited by 22 · see citing works
Itzhak, Y., Martin, J. L., & Ali, S. F. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05188.x · Cited by 21 · see citing works
Pargyline increases 6-hydroxydopamine levels in the neostriatum of methamphetamine-treated rats
Marek, G. J., Vosmer, G. L., & Seiden, L. S. (1990) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(90)90147-a · Cited by 20 · see citing works
Expression of autoimmune disease-related antigens by cells of the immune system
Mor, F., Boccaccio, G. L., & Unger, T. (1998) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19981015)54:2 · Cited by 19 · see citing works
Fleckenstein, A. E., Beyeler, M. L., Jackson, J. C., Wilkins, D. G., Gibb, J. W., & Hanson, G. R. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(97)00081-2 · Cited by 19 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
New Insights into the Mechanism of Action of Amphetamines
Fleckenstein, A. E., Volz, T. J., Riddle, E. L., Gibb, J. W., & Hanson, G. R. (2007) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.47.120505.105140 · Cited by 731 · see citing works
Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review
Deepmala, Slattery, J., Kumar, N., Delhey, L., Berk, M., Dean, O., Spielholz, C., & Frye, R. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.015 · Cited by 463 · see citing works
Methamphetamine causes microglial activation in the brains of human abusers
Sekine, Y., Ouchi, Y., Sugihara, G., Takei, N., Yoshikawa, E., Nakamura, K., Iwata, Y., Tsuchiya, K. J., Suda, S., Suzuki, K., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1179-08.2008 · Cited by 381 · see citing works
Self-citationPaulus, M. P., Tapert, S. F., & Schuckit, M. A. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.7.761 · Cited by 369 · see citing works
Thomas, D. M., Walker, P. D., Benjamins, J. A., Geddes, T. J., & Kuhn, D. M. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.070961 · Cited by 315 · see citing works
Jayanthi, S., Deng, X., Noailles, P., Ladenheim, B., & Cadet, J. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0295com · Cited by 278 · see citing works
Self-citationNeurotoxicity of substituted amphetamines: Molecular and cellular mechanisms
Cadet, J. L., Krasnova, I. N., Jayanthi, S., & Lyles, J. (2007) · Neurotoxicity Research · doi:10.1007/bf03033567 · Cited by 271 · see citing works
Self-citationDrugs and alcohol: Treating and preventing abuse, addiction and their medical consequences
Volkow, N. D., & Li, T. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.06.021 · Cited by 239 · see citing works
Jayanthi, S., Deng, X., Ladenheim, B., McCoy, M. T., Cluster, A. S., Cai, N.-S., & Cadet, J. L. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404990102 · Cited by 223 · see citing works
Self-citationNeurotoxicity of methamphetamine: Main effects and mechanisms
Jayanthi, S., Daiwile, A. P., & Cadet, J. L. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113795 · Cited by 230 · see citing works
Self-citationMethamphetamine: Effects on the brain, gut and immune system
Prakash, M. D., Tangalakis, K., Antonipillai, J., Stojanovska, L., Nurgali, K., & Apostolopoulos, V. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.03.009 · Cited by 220 · see citing works
Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity
LaVoie, M. J., Card, J. P., & Hastings, T. G. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.01.010 · Cited by 204 · see citing works
Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines
Thomas, D. M., Dowgiert, J., Geddes, T. J., Francescutti, D. M., Liu, X., & Kuhn, D. M. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.06.065 · Cited by 193 · see citing works
Vearrier, D., Greenberg, M. I., Miller, S. N., Okaneku, J., & Haggerty, D. A. (2012) · Disease-a-Month · doi:10.1016/j.disamonth.2011.09.004 · Cited by 191 · see citing works
Regulation of the dopamine transporter
Schmitt, K. C., & Reith, M. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05148.x · Cited by 188 · see citing works
Recent Advances in Methamphetamine Neurotoxicity Mechanisms and Its Molecular Pathophysiology
Yu, S., Zhu, L., Shen, Q., Bai, X., & Di, X. (2015) · Behavioural Neurology · doi:10.1155/2015/103969 · Cited by 176 · see citing works
Dietrich, J.-B., Mangeol, A., Revel, M.-O., Burgun, C., Aunis, D., & Zwiller, J. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.01.018 · Cited by 168 · see citing works
Dopaminergic neuron-specific oxidative stress caused by dopamine itself.
Miyazaki, I., & Asanuma, M. (2008) · PubMed · doi:10.18926/amo/30942 · Cited by 168 · see citing works
Zhang, L., Kitaichi, K., Fujimoto, Y., Nakayama, H., Shimizu, E., Iyo, M., & Hashimoto, K. (2006) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.05.015 · Cited by 159 · see citing works
Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse
Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148 · see citing works
Nguyen, E. C., McCracken, K. A., Liu, Y., Pouw, B., & Matsumoto, R. R. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.04.016 · Cited by 146 · see citing works
Wu, C.-W., Ping, Y., Yen, J., Chang, C., Wang, S., Yeh, C.-L., Chi, C., & Lee, H. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.01.011 · Cited by 143 · see citing works
Fukami, G., Hashimoto, K., Koike, K., Okamura, N., Shimizu, E., & Iyo, M. (2004) · Brain Research · doi:10.1016/j.brainres.2004.04.072 · Cited by 138 · see citing works
Moszczyńska, A., & Callan, S. P. (2017) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.238501 · Cited by 133 · see citing works
Thomas, D. M., & Kuhn, D. M. (2005) · Brain Research · doi:10.1016/j.brainres.2005.05.049 · Cited by 132 · see citing works
Cunha‐Oliveira, T., Rego, A. C., Cardoso, S. M., Borges, F., Swerdlow, R. H., Macedo, T., & Oliveira, C. R. (2006) · Brain Research · doi:10.1016/j.brainres.2006.03.061 · Cited by 126 · see citing works
Rose, M. E., & Grant, J. E. (2008) · Annals of Clinical Psychiatry · doi:10.1080/10401230802177656 · Cited by 121 · see citing works
Mandyam, C. D., Wee, S., Crawford, E. F., Eisch, A. J., Richardson, H. N., & Koob, G. F. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.04.010 · Cited by 120 · see citing works
Zhu, J. P. Q., Xu, W., & Angulo, J. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.02.055 · Cited by 119 · see citing works
Emerging research on methamphetamine
Maxwell, J. C. (2005) · Current Opinion in Psychiatry · doi:10.1097/01.yco.0000165592.52811.84 · Cited by 117 · see citing works
A Coat of Many Colors: Neuroimmune Crosstalk in Human Immunodeficiency Virus Infection
Kraft-Terry, S. D., Buch, S. J., Fox, H. S., & Gendelman, H. E. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.042 · Cited by 114 · see citing works
Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension
Chen, P.-I., Cao, A., Miyagawa, K., Tojais, N. F., Hennigs, J. K., Li, C. G., Sweeney, N. M., Inglis, A. S., Wang, L., Li, D., et al. (2017) · JCI Insight · doi:10.1172/jci.insight.90427 · Cited by 106 · see citing works
Muneer, P. M. A., Alikunju, S., Szlachetka, A. M., Murrin, L. C., & Haorah, J. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-23 · Cited by 104 · see citing works
Simões, A. P., Silva, A. P., Pereira, F. C., Marques, E., Grade, S., Milhazes, N., Borges, F., Ribeiro, C., & Macedo, T. R. A. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.09.044 · Cited by 104 · see citing works
Marcondes, M. C. G., Flynn, C. T., Watry, D. D., Zandonatti, M. A., & Fox, H. S. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090953 · Cited by 98 · see citing works
Beauvais, G., Atwell, K., Jayanthi, S., Ladenheim, B., & Cadet, J. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028946 · Cited by 97 · see citing works
Self-citationWong, A. W., McCallum, G. P., Jeng, W., & Wells, P. G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2557-08.2008 · Cited by 96 · see citing works
Astrocyte-derived metallothionein protects dopaminergic neurons from dopamine quinone toxicity
Miyazaki, I., Asanuma, M., Kikkawa, Y., Takeshima, M., Murakami, S., Miyoshi, K., Sogawa, N., & Kita, T. (2010) · Glia · doi:10.1002/glia.21112 · Cited by 96 · see citing works
Attenuated microglial activation mediates tolerance to the neurotoxic effects of methamphetamine
Thomas, D. M., & Kuhn, D. M. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02906.x · Cited by 95 · see citing works
Neuropeptide Y Protects against Methamphetamine-Induced Neuronal Apoptosis in the Mouse Striatum
Thiriet, N., Deng, X., Solinas, M., Ladenheim, B., Curtis, W., Goldberg, S. R., Palmiter, R. D., & Cadet, J. L. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4893-04.2005 · Cited by 91 · see citing works
Self-citationMethamphetamine-induced neurotoxicity: the road to Parkinson’s disease
Thrash, B., Kariharan, T., Ahuja, M., Suppiramaniam, V. D., & Dhanasekaran, M. (2009) · Pharmacological Reports · doi:10.1016/s1734-1140(09)70158-6 · Cited by 88 · see citing works
Du, S., Qiao, D., Chen, C., Chen, S., Liu, C., Lin, Z., Wang, H., & Xie, W. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00409 · Cited by 82 · see citing works
Kongsuphol, P., Mukda, S., Nopparat, C., Villarroel, A., & Govitrapong, P. (2008) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2008.00648.x · Cited by 81 · see citing works
Melega, W. P., Jorgensen, M. J., Laćan, G., Way, B. M., Pham, J., Morton, G. G., Cho, A. K., & Fairbanks, L. A. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301502 · Cited by 78 · see citing works
Genetically correlated effects of selective breeding for high and low methamphetamine consumption
Wheeler, J. M., Reed, C. L., Burkhart‐Kasch, S., Li, N., Cunningham, C. L., Janowsky, A. J., Franken, F. H., Wiren, K. M., Hashimoto, J. G., Scibelli, A. C., et al. (2009) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2009.00522.x · Cited by 77 · see citing works
Kanthasamy, A., ANANTHARAM, V., ALI, S. F., & KANTHASAMY, A. G. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1369.022 · Cited by 75 · see citing works
Krasnova, I. N., Ladenheim, B., & Cadet, J. L. (2005) · The FASEB Journal · doi:10.1096/fj.04-2881fje · Cited by 74 · see citing works
Self-citationPharmacogenetic Treatments for Drug Addiction: Cocaine, Amphetamine and Methamphetamine
Haile, C. N., Kosten, T. R., & Kosten, T. A. (2009) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990902825447 · Cited by 73 · see citing works
Protein expression profile in the striatum of acute methamphetamine-treated rats
Iwazaki, T., McGregor, I. S., & Matsumoto, I. (2006) · Brain Research · doi:10.1016/j.brainres.2006.04.052 · Cited by 72 · see citing works
Approaches to Prevent Dopamine Quinone-Induced Neurotoxicity
Miyazaki, I., & Asanuma, M. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9843-1 · Cited by 71 · see citing works
Shin, E., Duong, C., Nguyen, X. T., Li, Z., Bing, G., Bach, J., Park, D.-H., Nakayama, K. I., Ali, S. F., Kanthasamy, A., et al. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.04.001 · Cited by 76 · see citing works
Self-citationShafahi, M., Vaezi, G., Shajiee, H., Sharafi, S., & Khaksari, M. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2644-2 · Cited by 70 · see citing works
Methamphetamine Administration Causes Death of Dopaminergic Neurons in the Mouse Olfactory Bulb
Deng, X., Ladenheim, B., Jayanthi, S., & Cadet, J. L. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.010 · Cited by 70 · see citing works
Self-citationNeuropsychological deficits in adolescent methamphetamine abusers
King, G., Alicata, D., Cloak, C. C., & Chang, L. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1949-x · Cited by 70 · see citing works
Hashimoto, K., Tsukada, H., Nishiyama, S., Fukumoto, D., Kakiuchi, T., Shimizu, E., & Iyo, M. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300512 · Cited by 70 · see citing works
Role of nitrergic system in behavioral and neurotoxic effects of amphetamine analogs
Itzhak, Y., & Ali, S. F. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.08.004 · Cited by 67 · see citing works
Shepard, J. D., Chuang, D., Shaham, Y., & Morales, M. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0316-4 · Cited by 66 · see citing works
Huang, J., Zheng, Y., Gao, D., Hu, M., & Yuan, T. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00999 · Cited by 65 · see citing works
Hashimoto, K., Tsukada, H., Nishiyama, S., Fukumoto, D., Kakiuchi, T., & Iyo, M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.019 · Cited by 65 · see citing works
Anantharam, V., Lehrmann, E., Kanthasamy, A., Yang, Y., Banerjee, P., Becker, K. G., Freed, W. J., & Kanthasamy, A. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.02.003 · Cited by 65 · see citing works
Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion
Gillingwater, T. H. (2006) · Brain · doi:10.1093/brain/awl101 · Cited by 63 · see citing works
Attenuation of Cocaine and Methamphetamine Neurotoxicity by Coenzyme Q10
Klongpanichapak, S., Govitrapong, P., SHARMA, S. K., & Ebadi, M. (2006) · Neurochemical Research · doi:10.1007/s11064-005-9025-3 · Cited by 65 · see citing works
Cai, D., Huang, E., Luo, B., Yang, Y., ZHANG, F., Liu, C., Lin, Z., Xie, W.-B., & Wang, H. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.67 · Cited by 62 · see citing works
Robson, M. J., Turner, R. C., Naser, Z. J., McCurdy, C. R., Huber, J. D., & Matsumoto, R. R. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.04.009 · Cited by 60 · see citing works
The Scourge of Methamphetamine: Impact on a Level I Trauma Center
Swanson, S. M., Sise, C. B., Sise, M. J., Sack, D. I., Holbrook, T. L., & Paci, G. M. (2007) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0b013e318074d3ac · Cited by 61 · see citing works
Alteration of blood-brain barrier function by methamphetamine and cocaine
Dietrich, J. B. (2009) · Cell and Tissue Research · doi:10.1007/s00441-009-0777-y · Cited by 61 · see citing works
Thomas, D. M., Angoa‐Pérez, M., Francescutti, D. M., Shah, M. M., & Kuhn, D. M. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06950.x · Cited by 59 · see citing works
Interactions of HIV and methamphetamine: Cellular and molecular mechanisms of toxicity potentiation
Cadet, J. L., & Krasnova, I. N. (2007) · Neurotoxicity Research · doi:10.1007/bf03033915 · Cited by 59 · see citing works
Self-citationNeurotoxicology of Synthetic Cathinone Analogs
Angoa‐Pérez, M., Anneken, J. H., & Kuhn, D. M. (2016) · Current topics in behavioral neurosciences · doi:10.1007/7854_2016_21 · Cited by 60 · see citing works
Neurotoxic Effects of Methamphetamine
Thrash, B., Karuppagounder, S. S., Uthayathas, S., Suppiramaniam, V. D., & Dhanasekaran, M. (2009) · Neurochemical Research · doi:10.1007/s11064-009-0042-5 · Cited by 59 · see citing works
Persistence of tolerance to methamphetamine-induced monoamine deficits
Danaceau, J. P., Deering‐Rice, C. E., Day, J. E., Smeal, S. J., Johnson‐Davis, K. L., Fleckenstein, A. E., & Wilkins, D. G. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.11.045 · Cited by 59 · see citing works
Methamphetamine and MDMA (Ecstasy) Neurotoxicity: 'of Mice and Men'
Itzhak, Y., & Achat‐Mendes, C. (2004) · IUBMB Life · doi:10.1080/15216540410001727699 · Cited by 59 · see citing works
Kitamura, O., Tokunaga, I., Gotohda, T., & Kubo, S. (2006) · International Journal of Legal Medicine · doi:10.1007/s00414-006-0087-9 · Cited by 59 · see citing works
Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway
Sharikova, A. V., Quaye, E., Park, J. Y., Maloney, M. C., Desta, H., Thiyagarajan, R., Seldeen, K. L., Parikh, N. U., Sandhu, P., Khmaladze, A. T., et al. (2018) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-018-9787-4 · Cited by 59 · see citing works
Cheng, W. S., Garfein, R. S., Semple, S. J., Strathdee, S. A., Zians, J. K., & Patterson, T. L. (2009) · Substance Use & Misuse · doi:10.3109/10826080902869620 · Cited by 58 · see citing works
He, C., He, Q., Deng, C., Shi, L., Zhu, D., Fu, Y., Cao, H., & Cheng, J. (2010) · Chemical Communications · doi:10.1039/c0cc01972k · Cited by 58 · see citing works
Graham, D. L., Noailles, P.-A. H., & Cadet, J. L. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05269.x · Cited by 58 · see citing works
Self-citationCadet, J. L., McCoy, M. T., Cai, N. S., Krasnova, I. N., Ladenheim, B., Beauvais, G., Wilson, N., Wood, W. H., Becker, K. G., & Hodges, A. B. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007812 · Cited by 58 · see citing works
Self-citationCyclooxygenase-2 Is an Obligatory Factor in Methamphetamine-Induced Neurotoxicity
Thomas, D. M., & Kuhn, D. M. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.080242 · Cited by 58 · see citing works
Li, X., Wang, H., Qiu, P., & Luo, H. L. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.06.014 · Cited by 57 · see citing works
Golsorkhdan, S. A., Boroujeni, M. E., Aliaghaei, A., Abdollahifar, M., Ramezanpour, A., Nejatbakhsh, R., Anarkooli, I. J., Barfi, E., & Fridoni, M. J. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112300 · Cited by 55 · see citing works
He, J., Xu, H., Yang, Y., Zhang, X., & Li, X. (2004) · Brain Research · doi:10.1016/j.brainres.2004.05.060 · Cited by 55 · see citing works
Clemens, K. J., McGregor, I. S., Hunt, G. E., & Cornish, J. L. (2007) · Drug and Alcohol Review · doi:10.1080/09595230601036945 · Cited by 55 · see citing works
Huang, Y.-N., Yang, L.-Y., Wang, J.-Y., Lai, C.-C., Chiu, C.-T., & Wang, J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-015-9561-z · Cited by 54 · see citing works
Kaewsuk, S., Sae‐ung, K., Phansuwan‐Pujito, P., & Govitrapong, P. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.04.010 · Cited by 53 · see citing works
Caligiuri, M. P., & Buitenhuys, C. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300859 · Cited by 52 · see citing works
Methamphetamine and its impact on dental care.
Klasser, G. D., & Epstein, J. B. (2005) · PubMed · Cited by 52 · see citing works
Caspase-11 Plays an Essential Role in Methamphetamine-Induced Dopaminergic Neuron Apoptosis
Huang, W., Xie, W., Qiao, D., Qiu, P., Huang, E., Li, B., Chen, C., Liu, C., Wang, Q., Lin, Z., et al. (2015) · Toxicological Sciences · doi:10.1093/toxsci/kfv014 · Cited by 51 · see citing works
Sokolov, B. P., & Cadet, J. L. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300891 · Cited by 51 · see citing works
Self-citationThe Crosstalk Between Neurons and Glia in Methamphetamine-Induced Neuroinflammation
Shi, S., Chen, T., & Zhao, M. (2022) · Neurochemical Research · doi:10.1007/s11064-021-03513-9 · Cited by 51 · see citing works
Madden, L. J., Flynn, C. T., Zandonatti, M. A., May, M., Parsons, L. H., Katner, S. N., Henriksen, S. J., & Fox, H. S. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300575 · Cited by 50 · see citing works
Valvassori, S. S., Petronilho, F. C., Réus, G. Z., Steckert, A. V., Oliveira, V. B. M., Boeck, C. R., Kapczinski, F. P., Dal‐Pizzol, F., & Quevedo, J. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.02.012 · Cited by 49 · see citing works
Psychiatric Symptoms and HPA Axis Function in Adolescent Methamphetamine Users
King, G., Alicata, D., Cloak, C. C., & Chang, L. (2010) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-010-9206-y · Cited by 48 · see citing works
Chen, H., Wu, J., Zhang, J., Fujita, Y., Ishima, T., Iyo, M., & Hashimoto, K. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2619-3 · Cited by 49 · see citing works
Scheidweiler, K. B., & Huestis, M. A. (2006) · Journal of Chromatography B · doi:10.1016/j.jchromb.2006.03.020 · Cited by 48 · see citing works
Serotonin neurotoxins — past and present
Baumgarten, H. G., & Lachenmayer, L. (2004) · Neurotoxicity Research · doi:10.1007/bf03033455 · Cited by 48 · see citing works
Role of Sigma Receptors in Methamphetamine-Induced Neurotoxicity
Kaushal, N., & Matsumoto, R. R. (2011) · Current Neuropharmacology · doi:10.2174/157015911795016930 · Cited by 48 · see citing works
Hashimoto, T., Hashimoto, K., Matsuzawa, D., Shimizu, E., Sekine, Y., Inada, T., Ozaki, N., Iwata, N., Harano, M., Komiyama, T., et al. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30164 · Cited by 47 · see citing works
Environmental Enrichment does not Reduce the Rewarding and Neurotoxic Effects of Methamphetamine
Thiriet, N., Gennequin, B., Lardeux, V., Chauvet, C., Decressac, M., Janet, T., Jaber, M., & Solinas, M. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9158-2 · Cited by 47 · see citing works
Methamphetamine induces macropinocytosis in differentiated SH-SY5Y human neuroblastoma cells
Nara, A., Aki, T., Funakoshi, T., & Uemura, K. (2010) · Brain Research · doi:10.1016/j.brainres.2010.07.043 · Cited by 46 · see citing works
- Authors
- Cadet, J. L., Jayanthi, S., & Deng, X.
- Affiliations
- National Institutes of Health (US)
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 2003-10
- Volume
- 17
- Issue
- 13
- Pages
- 1775-1788
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W2083351059
- Cited by
- 286
- References
- 212
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 2 · 2023: 4 · 2022: 6 · 2021: 13 · 2020: 10 · 2019: 10 · 2018: 8 · 2017: 10 · 2016: 8 · 2015: 10 · 2014: 12 · 2013: 10 · 2012: 14
- FWCI
- 1.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The FASEB Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Institute on Drug Abuse
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cell death mechanisms and regulation
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- methamphetamine, neurotoxicity, neuronal apoptosis, nerve terminal degeneration, monoaminergic systems, reactive oxygen species, transcription factors, cell death genes, endoplasmic reticulum stress, mitochondrial dysfunction, caspase activation
- MeSH terms
- Animals, Humans, Methamphetamine, Models, Biological, Nerve Degeneration, Neurons, Signal Transduction, Apoptosis, Presynaptic Terminals, Cytoprotection, Neurotoxicity Syndromes, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review