The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Suprachiasmatic Nucleus: Use of 14 C-Labeled Deoxyglucose Uptake as a Functional Marker
Abstract
Glucose consumption of the rat suprachiasmatic nuclei (SCN) was studied under various experimental conditions by means of the [ 14 C]deoxyglucose (DG) technique. The results show that glucose consumption of the SCN, in contrast to other brain structures, is a function of both the time of day and environmental lighting conditions. These data are consistent with the hypothesis that the SCN have an essential role in circadian rhythm regulation and indicate that the DG technique may provide a novel approach for the study of the central neural mechanisms underlying circadian rhythm regulation.
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“This rostro-caudal difference may reflect cortical swelling in the prodromal phase that is also detected in human carriers of aggressive PSEN1 mutations46.”
From Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice (2026) · cites this paper as [46]
In the citing paper
“particularly the finding that cortical areas are 250 μm thicker in presymptomatic carriers of PSEN1 mutations than in controls at early prodromal stages, but are 250 μm thinner at late stages of disease (see figure 5 of Ref46).”
From Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice (2026) · cites this paper as [46]
Citations
Cites
Sokoloff, L., Reivich, M., Kennedy, C., Rosiers, M. H. D., Patlak, C. S., Pettigrew, K. D., Sakurada, O., & Shinohara, M. (1977) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1977.tb10649.x · Cited by 6,000
Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat
Moore, R. Y., & Eichler, V. B. (1972) · Brain Research · doi:10.1016/0006-8993(72)90054-6 · Cited by 2,135
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Research works printed but not linked: 22
- 10.1126/science.184.4144.1341 · DOI
- DUNNETT, C.W., NEW TABLES FOR MULTIPLE COMPARISONS WITH CONTROL, BIOMETRICS 20: 482 (1964). · DOI
- DUNNETT, C.W., A MULTIPLE COMPARISON PROCEDURE FOR COMPARING SEVERAL TREATMENTS WITH A CONTROL, JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION 50: 1096 (1955). · DOI
- HALBERG, F, CHRONOBIOLOGY, ANNUAL REVIEW OF PHYSIOLOGY 31: 675 (1969). · DOI
- INGVAR, D.H., BRAIN WORK: 520 (1975).
- 10.1126/science.1114332 · DOI
- 10.1126/science.177.4048.532 · DOI
- MENAKER, M, NEUROSCIENCES 3RD ST: 479 (1974).
- MOORE, R.Y., VISUAL PATHWAYS AND CENTRAL NEURAL CONTROL OF A CIRCADIAN-RHYTHM IN PINEAL SEROTONIN N-ACETYLTRANSFERASE ACTIVITY, BRAIN RESEARCH 71: 17 (1974). · DOI
- MOORE, R.Y., NEUROSCIENCES 3RD ST: 537 (1974).
- MOORE, R.Y., CENTRAL NEURAL MECHANISMS IN DIURNAL RHYTHM REGULATION AND NEUROENDOCRINE RESPONSES TO LIGHT, PSYCHONEUROENDOCRINOLOGY 1: 265 (1976). · DOI
- NISHINO, H, ROLE OF SUPRACHIASMATIC NUCLEI OF HYPOTHALAMUS IN PRODUCTION OF CIRCADIAN-RHYTHM, BRAIN RESEARCH 112: 45 (1976). · DOI
- NISHINO, H, RESPONSES OF NEURONS IN SUPRACHIASMATIC NUCLEI OF HYPOTHALAMUS TO PUTATIVE TRANSMITTERS, BRAIN RESEARCH 120: 167 (1977). · DOI
- PITTENDRIGH, C.S., NEUROSCIENCES 3 STUD: 437 (1974).
- PLUM, F, NEUROSCIENCES RESEARCH PROGRAM BULLETIN 14: 457 (1976).
- REIVICH, M, BRAIN WORK: 377 (1975).
- REIVICH, M, MEASUREMENT OF REGIONAL CEREBRAL BLOOD FLOW WITH ANTIPYRINE-14C IN AWAKE CATS, JOURNAL OF APPLIED PHYSIOLOGY 27: 296 (1969). · DOI
- ROGERS, A.W., TECHNIQUES AUTORADIO: 168 (1973).
- SAWAKI, Y, RETINOHYPOTHALAMIC PROJECTION - ELECTROPHYSIOLOGICAL EVIDENCE FOR EXISTENCE IN FEMALE RATS, BRAIN RESEARCH 120: 336 (1977). · DOI
- SOKOLOFF, L, BASIC NEUROCHEMISTRY: 388 (1976).
- STEPHAN, F.K., CIRCADIAN-RHYTHMS IN DRINKING BEHAVIOR AND LOCOMOTOR ACTIVITY OF RATS ARE ELIMINATED BY HYPOTHALAMIC-LESIONS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 69: 1583 (1972).
- 10.1126/science.942799 · DOI
Cited by
Sorted by citations
Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421
“Additionally, metabolic activity and glucose uptake in the SCN were dependent on time (14) as well as on expression of clock genes (15, 16) and proteins (17), illustrating clock activity in the SCN at the physiological and molecular levels.”
BackgroundCoordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,310
Transplanted Suprachiasmatic Nucleus Determines Circadian Period
Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853
Circadian physiology of metabolism
Panda, S. (2016) · Science · doi:10.1126/science.aah4967 · Cited by 1,092
Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors
Rutter, J., Reick, M., Wu, L. C., & McKnight, S. L. (2001) · Science · doi:10.1126/science.1060698 · Cited by 1,059
Metadata
- Authors
- Schwartz, W. J., & Gainer, H.
- Affiliations
- Neurology, Inc (US)
- National Institutes of Health (US)
- ORCID
- Schwartz, William J.
- Venue
- Science
- Published
- 1977-09-09
- Volume
- 197
- Issue
- 4308
- Pages
- 1089-1091
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2036301926
- Cited by
- 358
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 6 · 2021: 7 · 2020: 6 · 2019: 3 · 2018: 8 · 2017: 2 · 2016: 4 · 2015: 1 · 2014: 5 · 2013: 10 · 2012: 6
- FWCI
- 5.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- suprachiasmatic nucleus, glucose utilization, circadian regulation, circadian rhythm, light exposure, time of day, brain glucose metabolism
- MeSH terms
- Animals, Autoradiography, Circadian Rhythm, Deoxy Sugars, Deoxyglucose, Female, Glucose, Hypothalamus, Light, Supraoptic Nucleus, Rats
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