Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
Rizvi, Naiyer A., Hellmann, Matthew D., Snyder, Alexandra, Kvistborg, Pia, Makarov, Vladimir, Havel, Jonathan J., Lee, William, Yuan, Jianda +16 more·2015·Science
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- Acquired resistance to immunotherapy and future challengesNicholas P. Restifo, Mark John Smyth, Alexandra Snyder · 2016 · Nature reviews. Cancer
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- Microsatellite instability status determined by next‐generation sequencing and compared with PD ‐L1 and tumor mutational burden in 11,348 patientsAri M. Vanderwalde, David B. Spetzler, Nianqing Xiao, Zoran Gatalica, John Lindsay Marshall · 2018 · Cancer Medicine
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- Safety, efficacy and tumor mutational burden as a biomarker of overall survival benefit in chemo-refractory gastric cancer treated with toripalimab, a PD-1 antibody in phase Ib/II clinical trial NCT02915432Fenghua Wang, Xiaoli Wei, Fenggong Wang, Nong Xu, Lin Shen, Guanghai Dai, Xianglin Yuan, Yawen Chen, S. Yang, Jiawei Shi et al. · 2019 · Annals of Oncology
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- 'Final common pathway' of human cancer immunotherapy: targeting random somatic mutationsTran, Eric, Robbins, Paul F, Rosenberg, Steven A · 2017 · Nature Immunology
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- Targeting of cancer neoantigens with donor-derived T cell receptor repertoiresErlend Strønen, Mireille Toebes, Sander Kelderman, Marit M. van Buuren, Weiwen Yang, Nienke van Rooij, Marco Donia, Maxi-Lu Böschen, Fridtjof Lund‐Johansen, Johanna Olweus et al. · 2016 · Science
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- Temporal single-cell tracing reveals clonal revival and expansion of precursor exhausted T cells during anti-PD-1 therapy in lung cancerLiu, Baolin, Hu, Xueda, Feng, Kaichao, Gao, Ranran, Xue, Zhiqiang, Zhang, Sujie, Zhang, Yuanyuan, Corse, Emily, Hu, Yi, Han, Weidong et al. · 2021 · Nature Cancer
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- Immune-related gene expression profiling after PD-1 blockade in non–small cell lung carcinoma, head and neck squamous cell carcinoma, and melanomaPrat, Aleix, Navarro, Alejandro, Paré, Laia, Reguart, Noemí, Galván, Patricia, Pascual, Tomás, Martínez, Alex, Nuciforo, Paolo, Comerma, Laura, Alos, Llucia et al. · 2017 · Cancer Research
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- Epithelial–Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung AdenocarcinomaYanyan Lou, Lixia Diao, Edwin Roger Parra, Warren L. Denning, Limo Chen, You Hong Fan, Lauren A. Byers, Jing Wang, Vassiliki A. Papadimitrakopoulou, Carmen Behrens et al. · 2016 · Clinical Cancer Research
- EGFR mutation correlates with uninflamed phenotype and weak immunogenicity, causing impaired response to PD-1 blockade in non-small cell lung cancerDong, Zhong-Yi, Zhang, Jia-Tao, Liu, Si-Yang, Su, Jian, Zhang, Chao, Xie, Zhi, Zhou, Qing, Tu, Hai-Yan, Xu, Chong-Rui, Yan, Li-Xu et al. · 2017 · OncoImmunology
- Evaluation of POLE and POLD1 Mutations as Biomarkers for Immunotherapy Outcomes Across Multiple Cancer TypesFeng Wang, Qi Zhao, Ying-Nan Wang, Ying Jin, Ming-Ming He, Zexian Liu, Rui‐Hua Xu · 2019 · JAMA Oncology
- Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial SarcomaSandra P. D’Angelo, Luca Melchiori, Melinda S. Merchant, Donna B. Bernstein, John W. Glod, Rosandra Natasha Kaplan, Stephan A. Grupp, William D. Tap, Karen Chagin, Gwendolyn K. Binder et al. · 2018 · Cancer Discovery
- Classifying the evolutionary and ecological features of neoplasmsCarlo C. Maley, Athena Aktipis, Trevor A. Graham, Andrea Sottoriva, Amy M. Boddy, Michalina Janiszewska, Ariosto Siqueira Silva, Marco Gerlinger, Yinyin Yuan, Kenneth J. Pienta et al. · 2017 · Nature reviews. Cancer
- Tremelimumab as second-line or third-line treatment in relapsed malignant mesothelioma (DETERMINE): a multicentre, international, randomised, double-blind, placebo-controlled phase 2b trialMichele Maio, Arnaud Scherpereel, Luana Calabrò, Joachim G.J.V. Aerts, S. Cedrés, Alessandra Bearz, Kristiaan Nackaerts, Dean Anthony Fennell, Dariusz Mirosław Kowalski, Anne S. Tsao et al. · 2017 · The Lancet Oncology
- Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid TumorsQingyang Lei, Dan Wang, Kai Sun, Liping Wang, Yi Zhang · 2020 · Frontiers in Cell and Developmental Biology
- Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)Patrick J. Danaher, Sarah E. Warren, Rongze Olivia. Lu, Josue A. Samayoa, Amy H. Sullivan, Irena Pekker, Brett Wallden, Francesco Maria Marincola, Alessandra Cesano · 2018 · Journal for ImmunoTherapy of Cancer
- Current Landscape of Immunotherapy in Breast Cancer: A ReviewAdams, Sylvia, Gatti-Mays, Margaret E., Kalinsky, Kevin, Korde, Larissa A., Sharon, Elad, Amiri-Kordestani, Laleh, Bear, Harry, McArthur, Heather L., Frank, Elizabeth, Perlmutter, Jane et al. · 2019 · JAMA Oncology
- The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in CancerH. Courtney Hodges, Jacob G. Kirkland, Gerald R. Crabtree · 2016 · Cold Spring Harbor Perspectives in Medicine
- New insights into the role of
<scp>EMT</scp>
in tumor immune escapeTerry, Stéphane, Savagner, Pierre, Ortiz‐Cuaran, Sandra, Mahjoubi, Linda, Saintigny, Pierre, Thiery, Jean‐Paul, Chouaib, Salem · 2017 · Molecular Oncology
- Neutrophils dominate the immune cell composition in non-small cell lung cancerJulia Kargl, Stephanie Busch, Grace H. Y. Yang, Kyoung-Hee Kim, Mark L. Hanke, Heather E. Metz, Jesse J. Hubbard, Sylvia M. Lee, David K. Madtes, Martin W. McIntosh et al. · 2017 · Nature Communications
- Pembrolizumab in patients with thymic carcinoma: a single-arm, single-centre, phase 2 studyGiuseppe Giaccone, Chul Kim, Jillian Thompson, Colleen McGuire, Bhaskar Kallakury, Joeffrey J. Chahine, Maria A. Manning, Robin Mogg, Wendy M. Blumenschein, Ming Tony Tan et al. · 2018 · The Lancet Oncology
- Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLLWei Ding, Betsy R LaPlant, Timothy G. Call, Sameer Ashok Parikh, Jose Francisco Leis, Rong Lucy He, Tait D. Shanafelt, Sutapa Sinha, Jennifer G. Le‐Rademacher, Andrew L. Feldman et al. · 2017 · Blood
- Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevanceMaria Secrier, Xiaodun Li, Nadeera de Silva, Matthew Eldridge, Gianmarco Contino, Jan Bornschein, Shona MacRae, Nicola Grehan, Maria O’Donovan, Ahmad Miremadi et al. · 2016 · Nature Genetics
- Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapyTiffany R. Hodges, Martina Ott, Joanne Xiu, Zoran Gatalica, Jeffrey J. Swensen, Shouhao Zhou, Jason T. Huse, John de Groot, Shulin Li, Willem W. Overwijk et al. · 2017 · Neuro-Oncology
- Tumor immune evasion arises through loss of TNF sensitivityKearney, Conor J., Vervoort, Stephin J., Hogg, Simon J., Ramsbottom, Kelly M., Freeman, Andrew J., Lalaoui, Najoua, Pijpers, Lizzy, Michie, Jessica, Brown, Kristin K., Knight, Deborah A. et al. · 2018 · Science Immunology
- Multimodal integration of radiology, pathology and genomics for prediction of response to PD-(L)1 blockade in patients with non-small cell lung cancerVanguri, Rami S., Luo, Jia, Aukerman, Andrew T., Egger, Jacklynn V., Fong, Christopher J., Horvat, Natally, Pagano, Andrew, Araujo-Filho, Jose de Arimateia Batista, Geneslaw, Luke, Rizvi, Hira et al. · 2022 · Nature Cancer
- Predictive biomarkers in PD-1/PD-L1 checkpoint blockade immunotherapyXiangjiao Meng, Zhaoqin Huang, Feifei Teng, Ligang Xing, Jinming Yu · 2015 · Cancer Treatment Reviews
- Immunotherapy and stereotactic ablative radiotherapy (ISABR): a curative approach?Michael B. Bernstein, Sunil Krishnan, James W. Hodge, Joe Yujiao Chang · 2016 · Nature Reviews Clinical Oncology
- TIM-3 regulates CD103+ dendritic cell function and response to chemotherapy in breast cancerde Mingo Pulido, Álvaro, Gardner, Alycia, Hiebler, Shandi, Soliman, Hatem, Rugo, Hope S., Krummel, Matthew F., Coussens, Lisa M., Ruffell, Brian · 2018 · Cancer Cell
- Diminished efficacy of programmed death-(ligand)1 inhibition in STK11- and KEAP1-mutant lung adenocarcinoma is affected by KRAS mutation statusRicciuti, Biagio, Arbour, Kathryn C., Lin, Jessica J., Vajdi, Amir, Vokes, Natalie, Hong, Lingzhi, Zhang, Jianjun, Tolstorukov, Michael Y., Li, Yvonne Y., Spurr, Liam F. et al. · 2022 · Journal of Thoracic Oncology
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- Programmed Death-Ligand 1 Immunohistochemistry Testing: A Review of Analytical Assays and Clinical Implementation in Non–Small-Cell Lung CancerReinhard Büttner, John R. Gosney, Birgit Guldhammer Skov, Julien Adam, Noriko Motoi, Kenneth Joel Bloom, Manfred Dietel, John W. Longshore, Fernando López‐Ríos, Frederique Madeleine Penault-Llorca et al. · 2017 · Journal of Clinical Oncology
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- An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancerVoabil, Paula, de Bruijn, Marjolein, Roelofsen, Lisanne M., Hendriks, Sanne H., Brokamp, Simone, van den Braber, Marlous, Broeks, Annegien, Sanders, Joyce, Herzig, Petra, Zippelius, Alfred et al. · 2021 · Nature Medicine
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- T Cell–Inflamed versus Non-T Cell–Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy SelectionJonathan Trujillo, Randy F. Sweis, Riyue Bao, Jason J. Luke · 2018 · Cancer Immunology Research
- PD-1/PD-L1 Blockade Therapy in Advanced Non-Small-Cell Lung Cancer: Current Status and Future DirectionsLiliang Xia, Yuanyong Liu, Ying Wang · 2019 · The Oncologist
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- Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancerPosch, Florian, Silina, Karina, Leibl, Sebastian, Mündlein, Axel, Moch, Holger, Siebenhüner, Alexander, Samaras, Panagiotis, Riedl, Jakob, Stotz, Michael, Szkandera, Joanna et al. · 2018 · OncoImmunology
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- Immunotherapy in ovarian cancerKunle O. Odunsi · 2017 · Annals of Oncology
- Prospects of immune checkpoint modulators in the treatment of glioblastomaMatthias Preusser, Michael K. Lim, David A. Hafler, David A. Reardon, John Howard Sampson · 2015 · Nature Reviews Neurology
- Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapyGerald Goh, Trent J. Walradt, Vladimir Markarov, Astrid Blom, Nadeem Riaz, Ryan Doumani, K. Stafstrom, Ata S. Moshiri, Lola Yelistratova, Jonathan L. Levinsohn et al. · 2015 · Oncotarget
- Tumor neoantigens: from basic research to clinical applicationsTao Jiang, Tao Shi, Henghui Zhang, Jie Hu, Yuanlin Song, Jia Wei, Shengxiang Ren, Caicun Zhou · 2019 · Journal of Hematology & Oncology
- Cancer DNA vaccines: current preclinical and clinical developments and future perspectivesAlessandra Lopes, Gaëlle Vandermeulen, Véronique Préat A · 2019 · Journal of Experimental & Clinical Cancer Research
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- Multi-omics approaches in cancer research with applications in tumor subtyping, prognosis, and diagnosisOtília Menyhárt, Balázs Győrffy · 2021 · Computational and Structural Biotechnology Journal
- UVB-Induced Tumor Heterogeneity Diminishes Immune Response in MelanomaYochai Wolf, Osnat Bartok, Sushant Patkar, Gitit Bar Eli, Sapir Cohen, Kevin Litchfield, Ronen Levy, Alejandro Jiménez-Sánchez, Sophie Trabish, Joo Sang Lee et al. · 2019 · Cell
- The Immunoscore: Colon Cancer and BeyondHelen K. Angell, Daniela Bruni, J. Carl Barrett, Ronald Herbst, Jérôme Galon · 2019 · Clinical Cancer Research
- Immune activation and response to pembrolizumab in POLE-mutant endometrial cancerJanice M. Mehnert, Anshuman Panda, Judy Zhong, Kim Marie Hirshfield, Sherri Damare, Katherine Lane, Levi O. Sokol, Mark N. Stein, Lorna Rodriguez-Rodriquez, Howard L. Kaufman et al. · 2016 · Journal of Clinical Investigation
- Chemokines Modulate Immune Surveillance in Tumorigenesis, Metastasis, and Response to ImmunotherapyAnna E. Vilgelm, Ann J. Richmond · 2019 · Frontiers in Immunology
- Association of High Tumor Mutation Burden in Non–Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression LevelsBiagio Ricciuti, Xinan Wang, Joao V. Alessi, Hira A. Rizvi, Navin R. Mahadevan, Yvonne Y. Li, Andrew Polio, James R. Lindsay, Renato Umeton, Rileen Sinha et al. · 2022 · JAMA Oncology
- Combination immunotherapy: a road mapPatrick Alexander Ott, Frank Stephen Hodi, Howard L. Kaufman, Jon M. Wigginton, Jedd D. Wolchok · 2017 · Journal for ImmunoTherapy of Cancer
- Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based studyKuniko Sunami, Hitoshi Ichikawa, Takashi Kubo, Mamoru Kato, Yutaka Fujiwara, Akihiko Shimomura, Takafumi Koyama, Hiroki Kakishima, Mayuko Kitami, Hiromichi Matsushita et al. · 2019 · Cancer Science
- Exosomal PD-L1 promotes tumor growth through immune escape in non-small cell lung cancerDong Ha Kim, HyeongRyul Kim, Yun Jung Choi, Seon Ye Kim, Jung-Eun Lee, Ki Jung Sung, Young Hoon Sung, Chan‐Gi Pack, Minkyo Jung, Buhm Han et al. · 2019 · Experimental & Molecular Medicine
- Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell CarcinomaNicolás A. Giraldo, Étienne Becht, Yann Alexandre Vano, Florent Petitprez, Laetitia Lacroix, Pierre Validire, Rafael Sánchez-Salas, Alexandre Ingels, Stéphane Marie. Oudard, Audrey Moatti et al. · 2017 · Clinical Cancer Research
- Ovarian Cancer Immunotherapy and Personalized MedicineSusan M. Morand, Monika Devanaboyina, Hannah Staats, Laura Stanbery, John J. Nemunaitis · 2021 · International Journal of Molecular Sciences
- Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytesCyrille J. Cohen, Jared J. Gartner, Miryam Horovitz‐Fried, Katerina Shamalov, Kasia Trebska-McGowan, Valery V. Bliskovsky, Maria R. Parkhurst, Chen Ankri, Todd D. Prickett, Jessica S. Crystal et al. · 2015 · Journal of Clinical Investigation
- A panoply of errors: polymerase proofreading domain mutations in cancerEmily Rayner, Inge C. van Gool, Claire Palles, Stephen E. Kearsey, Tjalling Bosse, Ian P.M. Tomlinson, David N. Church · 2016 · Nature reviews. Cancer
- Improving radiotherapy in cancer treatment: Promises and challengesHelen H.W. Chen, Macus Tien Kuo · 2017 · Oncotarget
- Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and RecommendationsZishuo I. Hu, Jinru Shia, Zsofia Kinga Stadler, Anna M. Varghese, Marinela Capanu, Erin E. Salo‐Mullen, Maeve Aine Lowery, Luis Alberto Diaz, Diana L. Mandelker, Kenneth H. Yu et al. · 2018 · Clinical Cancer Research
- Mechanisms regulating T-cell infiltration and activity in solid tumorsLanitis, E., Dangaj, D., Irving, M., Coukos, G. · 2017 · Annals of Oncology
- Prospects for gene-engineered T cell immunotherapy for solid cancersChristopher Austin Klebanoff, Steven A. Rosenberg, Nicholas P. Restifo · 2016 · Nature Medicine
- EGFR mutation subtypes and response to immune checkpoint blockade treatment in non-small-cell lung cancerKatherine Hastings, Helena Alexandra Yu, Wen Wei, Francisco Sánchez-Vega, Michelle DeVeaux, Jungmin Choi, Hira A. Rizvi, Aaron Elliott Lisberg, Anna Truini, Christine Lydon et al. · 2019 · Annals of Oncology
- Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratificationAndrew M. Leader, John A. Grout, Barbara B. Maier, Barzin Y. Nabet, Matthew D. Park, Alexandra Tabachnikova, Christie Chang, Laura A. Walker, Alona Lansky, Jessica Le Bérichel et al. · 2021 · Cancer Cell
- Phase III Trial of Ipilimumab Combined With Paclitaxel and Carboplatin in Advanced Squamous Non–Small-Cell Lung CancerRamaswamy Govindan, Aleksandra Szczęsna, Myung‐Ju Ahn, Claus-Peter Schneider, Pablo González Mella, Fabrice Barlési, Baohui Han, Doina Elena Ganea, Joachim von Pawel, Vladimir Ivanovich Vladimirov et al. · 2017 · Journal of Clinical Oncology
- Epigenetic Therapeutics: A New Weapon in the War Against CancerNita Ahuja, Anup R. Sharma, Stephen B. Baylin · 2016 · Annual Review of Medicine
- Prevalence and mutational determinants of high tumor mutation burden in breast cancerRomualdo Barroso‐Sousa, Esha Jain, Ofir Cohen, D. Kim, Jorge E. Buendia-Buendia, Eric P. Winer, NU Lin, Sara M. Tolaney, Nikhil Wagle · 2020 · Annals of Oncology
- Implications of the tumor immune microenvironment for staging and therapeuticsJanis Marie Taube, Jérôme Galon, Lynette Marie Sholl, Scott J. Rodig, Tricia R. Cottrell, Nicolás A. Giraldo, Alexander Spyridon Baras, Sanjay S. Patel, Robert A. Anders, David L. Rimm et al. · 2017 · Modern Pathology
- Hyperprogressive disease: recognizing a novel pattern to improve patient managementStéphane Champiat, Roberto Ferrara, Christophe Massard, Benjamin Besse, Aurélien Marabelle, Jean‐Charles Soria, Charles Ferté · 2018 · Nature Reviews Clinical Oncology
- Randomized phase II trial of nivolumab versus nivolumab and ipilimumab for recurrent or persistent ovarian cancer: an NRG Oncology StudyZamarin, Dmitriy, Burger, Robert A., Sill, Michael W., Powell, Daniel J., Lankes, Heather A., Feldman, Michael D., Zivanovic, Oliver, Gunderson, Camille, Ko, Emily, Mathews, Cara et al. · 2020 · Journal of Clinical Oncology
- FDA Approval Summary: Pembrolizumab for the Treatment of Patients With Metastatic Non-Small Cell Lung Cancer Whose Tumors Express Programmed Death-Ligand 1Joohee Sul, Gideon Michael Blumenthal, Xiaoping Jiang, Kun He, Patricia Keegan, Richard Pazdur · 2016 · The Oncologist
- Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinomaChun Jye Lim, Yun Hua Lee, Lu Pan, Liyun Lai, Camillus Jian Hui Chua, Martin Wasser, Tony Kiat Hon Lim, Joe Poh-Sheng Yeong, Han Chong Toh, Ser Yee Lee et al. · 2018 · Gut
- Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal CancerLin, Anqi, Zhang, Jian, Luo, Peng · 2020 · Frontiers in Immunology