Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 297

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

Open access
Zhang, Yongyou, Desai, Amar, Yang, Sung Yeun, Bae, Ki Beom, Antczak, Monika I., Fink, Stephen P., Tiwari, Shruti, Willis, Joseph E., Williams, Noelle S., Dawson, Dawn M., Wald, David, Chen, Wei-Dong, Wang, Zhenghe, Kasturi, Lakshmi, Larusch, Gretchen A., He, Lucy, Cominelli, Fabio, Di Martino, Luca, Djuric, Zora, Milne, Ginger L., Chance, Mark, Sanabria, Juan, Dealwis, Chris, Mikkola, Debra, Naidoo, Jacinth, Wei, Shuguang, Tai, Hsin-Hsiung, Gerson, Stanton L., Ready, Joseph M., Posner, Bruce, Willson, James K. V., Markowitz, Sanford D.·2015·Science
DOI 10.1126/science.aaa2340
Open this paper in CoChat — free account

Abstract

A shot in the arm for damaged tissue: Tissue damage can be caused by injury, disease, and even certain medical treatments. There is great interest in identifying drugs that accelerate tissue regeneration and recovery, especially drugs that might benefit multiple organ systems. Zhang et al. describe a compound with this desired activity, at least in mice (see the Perspective by FitzGerald). SW033291 promotes recovery of the hematopoietic system after bone marrow transplantation, prevents the development of ulcerative colitis in the intestine, and accelerates liver regeneration after hepatic surgery. It acts by inhibiting an enzyme that degrades prostaglandins, lipid signaling molecules that have been implicated in tissue stem cell maintenance. Science , this issue 10.1126/science.aaa2340 ; see also p. 1208

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1126/science.aaa2340

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 45 references

Cited by

See all 297

Metadata

Authors
Zhang, Y., Desai, A., Yang, S. Y., Bae, K. B., Antczak, M. I., Fink, S. P., Tiwari, S., Willis, J. E., Williams, N. S., Dawson, D. M., Wald, D., Chen, W.-D., Wang, Z., Kasturi, L., Larusch, G. A., He, L., Cominelli, F., Di Martino, L., Djuric, Z., Milne, G. L., Chance, M., Sanabria, J., Dealwis, C., Mikkola, D., Naidoo, J., Wei, S., Tai, H.-H., Gerson, S. L., Ready, J. M., Posner, B., Willson, J. K. V., & Markowitz, S. D.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2015-06-12
Volume
348
Issue
6240
Pages
aaa2340-aaa2340
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.aaa2340
OpenAlex
W1542330291
Cited by
297
References
45
FWCI
16.07
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. https://app.cochat.ai/papers/10.1126/science.aaa2340
The paper
Zhang, Y., Desai, A., Yang, S. Y., Bae, K. B., Antczak, M. I., Fink, S. P., Tiwari, S., Willis, J. E., Williams, N. S., Dawson, D. M., Wald, D., Chen, W.-D., Wang, Z., Kasturi, L., Larusch, G. A., He, L., Cominelli, F., Di Martino, L., Djuric, Z., . . . Markowitz, S. D. (2015). Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. Science. https://doi.org/10.1126/science.aaa2340

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.