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Cited by 297

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

Open access
Zhang, Yongyou, Desai, Amar, Yang, Sung Yeun, Bae, Ki Beom, Antczak, Monika I., Fink, Stephen P., Tiwari, Shruti, Willis, Joseph E., Williams, Noelle S., Dawson, Dawn M., Wald, David, Chen, Wei-Dong, Wang, Zhenghe, Kasturi, Lakshmi, Larusch, Gretchen A., He, Lucy, Cominelli, Fabio, Di Martino, Luca, Djuric, Zora, Milne, Ginger L., Chance, Mark, Sanabria, Juan, Dealwis, Chris, Mikkola, Debra, Naidoo, Jacinth, Wei, Shuguang, Tai, Hsin-Hsiung, Gerson, Stanton L., Ready, Joseph M., Posner, Bruce, Willson, James K. V., Markowitz, Sanford D.·2015·Science
DOI 10.1126/science.aaa2340
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Abstract

A shot in the arm for damaged tissue: Tissue damage can be caused by injury, disease, and even certain medical treatments. There is great interest in identifying drugs that accelerate tissue regeneration and recovery, especially drugs that might benefit multiple organ systems. Zhang et al. describe a compound with this desired activity, at least in mice (see the Perspective by FitzGerald). SW033291 promotes recovery of the hematopoietic system after bone marrow transplantation, prevents the development of ulcerative colitis in the intestine, and accelerates liver regeneration after hepatic surgery. It acts by inhibiting an enzyme that degrades prostaglandins, lipid signaling molecules that have been implicated in tissue stem cell maintenance. Science , this issue 10.1126/science.aaa2340 ; see also p. 1208

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Crossref · 10.1126/science.aaa2340

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Metadata

Authors
Zhang, Y., Desai, A., Yang, S. Y., Bae, K. B., Antczak, M. I., Fink, S. P., Tiwari, S., Willis, J. E., Williams, N. S., Dawson, D. M., Wald, D., Chen, W.-D., Wang, Z., Kasturi, L., Larusch, G. A., He, L., Cominelli, F., Di Martino, L., Djuric, Z., Milne, G. L., Chance, M., Sanabria, J., Dealwis, C., Mikkola, D., Naidoo, J., Wei, S., Tai, H.-H., Gerson, S. L., Ready, J. M., Posner, B., Willson, J. K. V., & Markowitz, S. D.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2015-06-12
Volume
348
Issue
6240
Pages
aaa2340-aaa2340
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.aaa2340
OpenAlex
W1542330291
Cited by
297
References
45
FWCI
16.07
Type
journal article
Language
en
Open access
green

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.