Activation of proto-oncogenes by disruption of chromosome neighborhoods

Hnisz, Denes, Weintraub, Abraham S., Day, Daniel S., Valton, Anne-Laure, Bak, Rasmus O., Li, Charles H., Goldmann, Johanna, Lajoie, Bryan R. +9 more·2016·Science

Cited by (1,000)

Items 101–200 of 1,000

  1. CTCF shapes chromatin structure and gene expression in health and disease
    Bondita Dehingia, Małgorzata Milewska, Marcin Janowski, Aleksandra Pękowska · 2022 · EMBO Reports
  2. Homeobox oncogene activation by pan-cancer DNA hypermethylation
    Jianzhong Su, Yung‐Hsin Huang, Xiaodong Cui, Xinyu Wang, Xiaotian Zhang, Yong Lei, Jianfeng Xu, Xueqiu Lin, Kaifu Chen, Jie Lv et al. · 2018 · Genome biology
  3. Non-coding driver mutations in human cancer
    Kerryn Elliott, Erik Larsson · 2021 · Nature reviews. Cancer
  4. The chromosome folding problem and how cells solve it
    Dekker, Job, Mirny, Leonid A. · 2024 · Cell
  5. Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor
    Xiaoyang Zhang, Peter S. Choi, Joshua M. Francis, Galen F. Gao, Joshua David Campbell, Aruna Ramachandran, Yoichiro Mitsuishi, Gavin Ha, Juliann Shih, Francisca Vázquez et al. · 2017 · Cancer Discovery
  6. Loop stacking organizes genome folding from TADs to chromosomes
    Antonina Hafner, Minhee Park, Scott E. Berger, Sedona E. Murphy, Elphège Pierre Nora, Alistair Nicol Boettiger · 2023 · Molecular Cell
  7. Characterization of noncoding regulatory DNA in the human genome
    Ran Elkon, Reuven Agami · 2017 · Nature Biotechnology
  8. Nuclear Mechanopathology and Cancer Diagnosis
    Caroline Uhler, G. V. Shivashankar · 2018 · Trends in cancer
  9. Cancer epigenetics: Past, present and future
    Jae Eun Lee, Mi‐Young Kim · 2021 · Seminars in Cancer Biology
  10. Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
    Noèlia Díaz, Kai Kruse, Tabea Erdmann, Annette M. Staiger, German Ott, Georg Lenz, Juan M. Vaquerizas · 2018 · Nature Communications
  11. ChIA-PET2: a versatile and flexible pipeline for ChIA-PET data analysis
    Guipeng Li, Yang Chen, M. Snyder, Michael Q. Zhang · 2016 · Nucleic Acids Research
  12. BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells
    D. Debruyne, Ruben Dries, Satyaki Sengupta, Davide Seruggia, Yang Gao, Bandana Sharma, Hao Huang, L. Moreau, Michael Mclane, Daniel S. Day et al. · 2019 · Nature
  13. Principles of Chromosome Architecture Revealed by Hi-C
    Eagen, Kyle P. · 2018 · Trends in Biochemical Sciences
  14. Three-dimensional genome rewiring in loci with human accelerated regions
    Keough, Kathleen C., Whalen, Sean, Inoue, Fumitaka, Przytycki, Pawel F., Fair, Tyler, Deng, Chengyu, Steyert, Marilyn, Ryu, Hane, Lindblad-Toh, Kerstin, Karlsson, Elinor et al. · 2023 · Science
  15. Dynamic Competition of Polycomb and Trithorax in Transcriptional Programming
    Mitzi I. Kuroda, Hyuckjoon Kang, Sandip De, Judith A. Kassis · 2020 · Annual Review of Biochemistry
  16. Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening
    Jimin Tan, Nina Shenker-Tauris, Javier Rodriguez-Hernaez, Eric Wang, Theodore Sakellaropoulos, Francesco E. Boccalatte, Palaniraja Thandapani, Jane A. Skok, Iannis Aifantis, David Fenyö et al. · 2023 · Nature Biotechnology
  17. HACER: an atlas of human active enhancers to interpret regulatory variants
    Jing Wang, Xizhen Dai, Lynne D. Berry, Joy D. Cogan, Qi Liu, Yu Shyr · 2018 · Nucleic Acids Research
  18. Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
    Celestia Fang, Zhenjia Wang, Cui-Juan Han, Stephanie L. Safgren, K. Helmin, Emmalee R. Adelman, V. Serafin, Giuseppe Basso, Kyle P. Eagen, Alexandre Gaspar-Maia et al. · 2020 · Genome Biology
  19. DNA Methylation and Genetic Aberrations in Gastric Cancer
    Genki Usui, Keisuke Matsusaka, Yasunobu Mano, Masayuki Urabe, Sayaka Funata, Masashi Fukayama, Tetsuo Ushiku, Atsushi Kaneda · 2020 · Digestion
  20. Annexin A1 as a Regulator of Immune Response in Cancer
    Thaise Gonçalves Araújo, Sara Teixeira Soares Mota, Helen Soares Valença Ferreira, Matheus Alves Ribeiro, Luíz Ricardo Goulart, Lara Vecchi · 2021 · Cells
  21. Epigenetic regulation in cancer
    Minzhi Gu, Bo Ren, Yuan Fang, Jie Ren, Xiaohong Liu, Xing Wang, Feihan Zhou, Ruiling Xiao, Xiyuan Luo, Lei You et al. · 2024 · MedComm
  22. Pan-cancer analysis of whole genomes
    Peter J. Campbell, Gaddy Getz, Joshua M. Stuart, Jan O. Korbel, Lincoln David Stein · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Enhancer accessibility and CTCF occupancy underlie asymmetric TAD architecture and cell type specific genome topology
    Barrington, Christopher, Georgopoulou, Dimitra, Pezic, Dubravka, Varsally, Wazeer, Herrero, Javier, Hadjur, Suzana · 2019 · Nature Communications
  24. Super-enhancers: critical roles and therapeutic targets in hematologic malignancies
    Yunlu Jia, Wee Joo Chng, Jianbiao Zhou · 2019 · Journal of Hematology & Oncology
  25. Structural variations in cancer and the 3D genome
    Frank P. B. Dubois, Nikos Sidiropoulos, Joachim Weischenfeldt, Rameen Beroukhim · 2022 · Nature reviews. Cancer
  26. Enhancer deregulation in cancer and other diseases
    Hans‐Martin Herz · 2016 · BioEssays
  27. Chromatin features constrain structural variation across evolutionary timescales
    Geoffrey Fudenberg, Katherine S. Pollard · 2019 · Proceedings of the National Academy of Sciences
  28. Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments
    Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Sivakumar, Aishwarya, Kerr, Alastair R.W., Schirmer, Eric C. · 2017 · Genome Research
  29. Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration
    Bojana Lucic, Heng‐Chang Chen, Maja Kuzman, Eduard Valera Zorita, Julia Wegner, Vera Minneker, Wei Wang, Raffaele Fronza, Stefanie Laufs, Manfred Schmidt et al. · 2019 · Nature Communications
  30. Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
    Jelena Petrovic, Yeqiao Zhou, Maria Fasolino, Naomi Goldman, Gregory W. Schwartz, Maxwell R. Mumbach, Son C. Nguyen, Kelly Rome, Yogev Sela, Zachary Zapataro et al. · 2019 · Molecular Cell
  31. Epigenetic maintenance of topological domains in the highly rearranged gibbon genome
    Lazar, Nathan H., Nevonen, Kimberly A., O'Connell, Brendan, McCann, Christine, O'Neill, Rachel J., Green, Richard E., Meyer, Thomas J., Okhovat, Mariam, Carbone, Lucia · 2018 · Genome Research
  32. STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma.
    D. Surdez, Sakina Zaidi, S. Grossetête, K. Laud-Duval, A. Ferré, Lieke Mous, Thomas Vourc’h, F. Tirode, G. Pierron, V. Raynal et al. · 2021 · Cancer Cell
  33. Condensin II drives large-scale folding and spatial partitioning of interphase chromosomes in Drosophila nuclei
    Leah F. Rosin, Son C. Nguyen, Eric F. Joyce · 2018 · PLoS Genetics
  34. Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks
    Helen Zhu, Liis Uusküla-Reimand, Keren Isaev, Lina Wadi, Azad Alizada, Shimin Shuai, Vincent Huang, Dike Aduluso-Nwaobasi, Marta Paczkowska, Diala Abd-Rabbo et al. · 2020 · Molecular Cell
  35. Structural variants drive context-dependent oncogene activation in cancer
    Zhichao Xu, Dong-Sung Lee, Sahaana Chandran, Victoria T. Le, Rosalind Bump, Jean Yasis, Sofia Dallarda, Samantha Marcotte, Benjamin Clock, Nicholas K. Haghani et al. · 2022 · Nature
  36. Biologic and Therapeutic Implications of Genomic Alterations in Acute Lymphoblastic Leukemia
    Ilaria Iacobucci, Shunsuke Kimura, Charles Grenfell Mullighan · 2021 · Journal of Clinical Medicine
  37. ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry
    Lu Wang, Tze King Tan, Adam David Durbin, Mark W. Zimmerman, Brian J. Abraham, Shi Hao Tan, Phuong Cao Thi Ngoc, Nina Weichert‐Leahey, Koshi Akahane, Lee N. Lawton et al. · 2019 · Nature Communications
  38. Cross-species chromatin interactions drive transcriptional rewiring in Epstein–Barr virus–positive gastric adenocarcinoma
    A. Okabe, K. Huang, K. Matsusaka, Fukuyo Masaki, Manjie Xing, X. Ong, Takayuki Hoshii, Genki Usui, M. Seki, Yasunobu Mano et al. · 2020 · Nature Genetics
  39. HiTAD: detecting the structural and functional hierarchies of topologically associating domains from chromatin interactions
    Xiaotao Wang, Wang Cui, Cheng Peng · 2017 · Nucleic Acids Research
  40. Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS
    David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek et al. · 2018 · Nature Communications
  41. CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia
    John Anto Pulikkan, Mahesh Bhaskar Hegde, Hafiz Mohd Ahmad, Houda Belaghzal, Anuradha Illendula, Jun Yu, Kelsey O’Hagan, Jianhong Ou, Carsten Müller‐Tidow, Scot A. Wolfe et al. · 2018 · Cell
  42. Small genomic insertions form enhancers that misregulate oncogenes
    Brian J. Abraham, Denes Hnisz, Abraham S. Weintraub, Nicholas P. Kwiatkowski, Charles H. Li, Zhaodong Li, Nina Weichert‐Leahey, Sunniyat Rahman, Yu Liu, Julia Etchin et al. · 2017 · Nature Communications
  43. Genome-wide epigenomic profiling for biomarker discovery
    René A. M. Dirks, Hendrik G. Stunnenberg, Hendrik Marks · 2016 · Clinical Epigenetics
  44. Transcription Factor-Directed Re-Wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming Toward Trans-differentiation
    Alessandra Dall’Agnese, Luca Caputo, C. Nicoletti, J. di Iulio, A. Schmitt, Sole Gatto, Yarui Diao, Zhen Ye, M. Forcato, Ranjan J. Perera et al. · 2019 · Molecules and Cells
  45. Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations
    Stanley Zhou, Aislinn E. Treloar, Mathieu Lupien · 2016 · Cancer Discovery
  46. TADs and their borders: free movement or building a wall?
    Li-Hsin Chang, Sourav Ghosh, D. Noordermeer · 2019 · Journal of Molecular Biology
  47. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML
    Zuzana Tóthová, Anne-Laure Valton, Rebecca A. Gorelov, Mounica Vallurupalli, John Michael Krill-Burger, Amie L. Holmes, Catherine C. Landers, J. Erika Haydu, Edyta Małolepsza, Christina R. Hartigan et al. · 2020 · JCI Insight
  48. Epigenetics in Cancer: A Hematological Perspective
    Maximilian F. Stahl, Nathan Kohrman, Steven D. Gore, Tae Kon Kim, Amer Methqal Zeidan, Thomas Prébet · 2016 · PLoS Genetics
  49. Computational methods for analysing multiscale 3D genome organization
    Yang Zhang, Lorenzo Boninsegna, Muyu Yang, Tom Misteli, Frank Alber, Jian Ma · 2023 · Nature Reviews Genetics
  50. Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test
    Wen-Bao Yu, Bing He, Kai Tan · 2017 · Nature Communications
  51. Heat Shock Factor 1 Drives Intergenic Association of Its Target Gene Loci upon Heat Shock
    Surabhi Chowdhary, Amoldeep S. Kainth, David Pincus, David S. Gross · 2019 · Cell Reports
  52. Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment
    Celeste D. Rosencrance, Haneen Ammouri, Qi Yu, Tiffany Ge, Emily Jane Rendleman, Stacy A. Marshall, Kyle P. Eagen · 2020 · Molecular Cell
  53. Oncogenic super-enhancer formation in tumorigenesis and its molecular mechanisms
    Qunying Jia, Shuhua Chen, Yuan Tan, Yuejin Li, Faqing Tang · 2020 · Experimental & Molecular Medicine
  54. Cancer Evolution: A Multifaceted Affair
    Giovanni Ciriello, Luca Magnani, Sarah J. Aitken, Leila Akkari, Sam Behjati, Douglas Hanahan, Dan Avi Landau, Núria López-Bigas, Darío G. Lupiáñez, Jean‐Christophe Marine et al. · 2023 · Cancer Discovery
  55. Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia
    Regina Wan Ju Wong, Phuong Cao Thi Ngoc, Wei Zhong Leong, Alice Wei Yee Yam, Tinghu Zhang, Kaori Asamitsu, Shinsuke Iida, Takashi Okamoto, Ryuzo Ueda, Nathanael S. Gray et al. · 2017 · Blood
  56. Epigenome editing strategies for the functional annotation of CTCF insulators
    Tarjan, Daniel R., Flavahan, William A., Bernstein, Bradley E. · 2019 · Nature Communications
  57. TADCompare: An R Package for Differential and Temporal Analysis of Topologically Associated Domains
    Kellen G. Cresswell, Mikhail G. Dozmorov · 2020 · Frontiers in Genetics
  58. Illuminating the noncoding genome in cancer
    Xiaoyang Zhang, Matthew M. Meyerson · 2020 · Nature Cancer
  59. Common DNA sequence variation influences 3-dimensional conformation of the human genome
    David U. Gorkin, Yunjiang Qiu, Ming Hu, Kipper Fletez‐Brant, Tristin Liu, Anthony D. Schmitt, Amina Noor, Joshua Chiou, Kyle J. Gaulton, Jonathan L. Sebat et al. · 2019 · Genome biology
  60. multiHiCcompare: joint normalization and comparative analysis of complex Hi-C experiments
    John C. Stansfield, Kellen G. Cresswell, Mikhail G. Dozmorov · 2019 · Bioinformatics
  61. The role of 3D chromatin domains in gene regulation: a multi-facetted view on genome organization
    Daniel M. Ibrahim, Stefan Mundlos · 2020 · Current Opinion in Genetics & Development
  62. Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection
    Qiang Wu, Ya Guo, Yujia Lu, Jingwei Li, Ya Guo, Zhilian Jia · 2020 · Genome biology
  63. Chromatin dependencies in cancer and inflammation
    Marazzi, Ivan, Greenbaum, Benjamin D., Low, Diana H. P., Guccione, Ernesto · 2018 · Nature Reviews Molecular Cell Biology
  64. Forces driving the three‐dimensional folding of eukaryotic genomes
    Álvaro Rada-Iglesias, Frank G. Grosveld, Argyris Papantonis · 2018 · Molecular Systems Biology
  65. A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases
    Yiqun Zhang, Lixing Yang, Melanie H. Kucherlapati, Fengju Chen, Angela G. Hadjipanayis, Angeliki Pantazi, Christopher Aaron Bristow, Eunjung Alice Lee, Harshad S. Mahadeshwar, Jiabin Tang et al. · 2018 · Cell Reports
  66. Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types
    Vera B. Kaiser, Martin S. Taylor, Colin A M Semple · 2016 · PLoS Genetics
  67. Tissue‐specific Hi‐C analyses of rice, foxtail millet and maize suggest non‐canonical function of plant chromatin domains
    Pengfei Dong, Xiaoyu Tu, Haoxuan Li, Jianhua Zhang, Donald Scott Grierson, Pinghua Li, Silin Zhong · 2019 · Journal of Integrative Plant Biology
  68. Simultaneous single-cell three-dimensional genome and gene expression profiling uncovers dynamic enhancer connectivity underlying olfactory receptor choice
    Honggui Wu, Jiankun Zhang, Fanchong Jian, Jinxin Chen, Yinghui Zheng, Longzhi Tan, Xiaoliang Sunney Xie · 2024 · Nature Methods
  69. Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy
    Luay Matthew Almassalha, Greta M. Bauer, John E. Chandler, Scott Gladstein, Lusik Cherkezyan, Yolanda Stypula‐Cyrus, Samuel Edward Weinberg, Di Zhang, Peder Thusgaard Ruhoff, Hemant K. Roy et al. · 2016 · Proceedings of the National Academy of Sciences
  70. Topologically associated domains: a successful scaffold for the evolution of gene regulation in animals
    Rafael D. Acemel, Ignacio Maeso, José Luis Gómez-Skármeta · 2017 · Wiley Interdisciplinary Reviews Developmental Biology
  71. The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist
    Joke Gerarda van Bemmel, Rafael Galupa, Chris Gard, Nicolas Servant, Christel Picard, James O. J. Davies, Anthony J. Szempruch, Yinxiu Zhan, Jan Jakub Żylicz, Elphège Pierre Nora et al. · 2019 · Nature Genetics
  72. A MicroRNA Linking Human Positive Selection and Metabolic Disorders
    Lifeng Wang, Nasa Sinnott-Armstrong, Alexandre Wagschal, Abigail R. Wark, João Paulo Camporez, Rachel J. Perry, Fei Ji, Yoojin Sohn, Justin D. Oh, Su Wu et al. · 2020 · Cell
  73. A cohesin traffic pattern genetically linked to gene regulation
    Anne-Laure Valton, Sergey V. Venev, Barbara Mair, Eraj Shafiq Khokhar, Amy H.Y. Tong, Matej Ušaj, Katherine Chan, Athma A. Pai, Jason Moffat, Job Dekker · 2022 · Nature Structural & Molecular Biology
  74. Three-dimensional genome architecture and emerging technologies: looping in disease
    A. Mishra, R. Hawkins · 2017 · Genome Medicine
  75. Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at oncogenic loci
    Sungalee, Stephanie, Liu, Yuanlong, Lambuta, Ruxandra A., Katanayeva, Natalya, Donaldson Collier, Maria, Tavernari, Daniele, Roulland, Sandrine, Ciriello, Giovanni, Oricchio, Elisa · 2021 · Nature Genetics
  76. High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
    Yiqun Zhang, Fengju Chen, Nuno A. Fonseca, Yao He, Masashi Fujita, Hidewaki Nakagawa, Zemin Zhang, Alvis Brāzma, PCAWG Transcriptome Working Group, Samirkumar B. Amin et al. · 2020 · Nature Communications
  77. In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation
    Chiara Anania, Rafael D. Acemel, Johanna Jedamzick, Adriano Bolondi, Giulia Cova, Norbert Brieske, Ralf Kühn, Lars Wittler, Francisca Martinez Real, Darío G. Lupiáñez · 2022 · Nature Genetics
  78. Understanding the 3D genome: Emerging impacts on human disease
    Anton Krumm, Zhijun Duan · 2018 · Seminars in Cell and Developmental Biology
  79. Enhancers and chromatin structures: regulatory hubs in gene expression and diseases
    Zhenhua Hu, Wee‐Wei Tee · 2017 · Bioscience Reports
  80. Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes
    Eric Minwei Liu, Alexander Martinez‐Fundichely, Bianca Jay Diaz, Boaz E. Aronson, Tawny N. Cuykendall, Matthew J. MacKay, Priyanka Dhingra, Elissa W.P. Wong, Ping Chi, Effie Apostolou et al. · 2019 · Cell Systems
  81. 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
    Minjun Yang, Setareh Safavi, E. L. Woodward, Nicolas Duployez, Linda Olsson, Jonas Ungerbäck, Mikael Sigvardsson, Marketa Kubricanova Zaliova, Jan Zuna, Thoas Fioretos et al. · 2020 · Blood
  82. Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer
    Farhoud Faraji, Munfarid A Zaidi, Carole Fakhry, Daria A. Gaykalova · 2017 · Microbes and Infection
  83. The human leukemia virus HTLV-1 alters the structure and transcription of host chromatin in cis
    Anat Melamed, Hiroko Yaguchi, Michi Miura, Aviva Witkover, Tomas W. Fitzgerald, Ewan Birney, Charles R. M. Bangham · 2018 · eLife
  84. Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features
    Kai Yan, Jaclyn Andricovich, Zhouhao Zeng, Jun Zhu, Alexandros Tzatsos, Weiqun Peng · 2018 · Nature Communications
  85. CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops
    Yu Guo, Andrew A. Perez, D. Hazelett, G. Coetzee, S. Rhie, P. Farnham · 2018 · Genome Biology
  86. diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data
    Caleb A. Lareau, Martin J. Aryee · 2017 · Bioinformatics
  87. Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia
    Duohui Jing, Yizhou Huang, Xiaoyun Liu, Keith C.S. Sia, Julia Hlavka-Zhang, Xiaolu Tai, Meng Wang, Cara E. Toscan, Hannah McCalmont, Kathryn Evans et al. · 2018 · Cancer Cell
  88. APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL
    Z Li, Brian J. Abraham, Alla Berezovskaya, N Farah, Y Liu, Theresa E. León, Adele Kay Fielding, Shi Hao Tan, Takaomi Sanda, Abraham S. Weintraub et al. · 2017 · Leukemia
  89. Order and disorder: abnormal 3D chromatin organization in human disease
    Chiara Anania, Darío G. Lupiáñez · 2019 · Briefings in Functional Genomics
  90. CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression
    Martin Franke, Elisa de la Calle‐Mustienes, Ana Neto, María Almuedo‐Castillo, Ibai Irastorza-Azcárate, Rafael D. Acemel, Juan J. Tena, José M. Santos-Pereira, José Luis Gómez-Skármeta · 2021 · Nature Communications
  91. Perspectives: using polymer modeling to understand the formation and function of nuclear compartments
    Noëlle Haddad, Daniel Jost, Cédric Vaillant · 2017 · Chromosome Research
  92. Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation
    Hongbo Yang, Hui Zhang, Yu Luan, Tingting Liu, Wentao Yang, Kathryn G. Roberts, Maoxiang Qian, Bo Zhang, Wenjian Yang, Virginia Pérez-Andreu et al. · 2022 · Nature Genetics
  93. Enhancers: bridging the gap between gene control and human disease
    Jaret M. Karnuta, Peter C. Scacheri · 2018 · Human Molecular Genetics
  94. Cornelia de Lange syndrome: from molecular diagnosis to therapeutic approach
    Patrizia Sarogni, Maria Michela Pallotta, Antonio Musio · 2019 · Journal of Medical Genetics
  95. TAD evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function
    Okhovat, Mariam, VanCampen, Jake, Nevonen, Kimberly A., Harshman, Lana, Li, Weiyu, Layman, Cora E., Ward, Samantha, Herrera, Jarod, Wells, Jackson, Sheng, Rory R. et al. · 2023 · Nature Communications
  96. High-Throughput Approaches to Pinpoint Function within the Noncoding Genome
    Antonino Montalbano, Matthew C. Canver, Neville E. Sanjana · 2017 · Molecular Cell
  97. Reprogramming: identifying the mechanisms that safeguard cell identity
    Justin Brumbaugh, Bruno Di Stefano, Konrad Hochedlinger · 2019 · Development
  98. A walk through the SMC cycle: From catching DNAs to shaping the genome
    Roel Oldenkamp, Benjamin D. Rowland · 2022 · Molecular Cell
  99. Three-dimensional chromatin in disease: What holds us together and what drives us apart?
    Daniel M. Ibrahim, Stefan Mundlos · 2020 · Current Opinion in Cell Biology
  100. ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis
    Wei Zhong Leong, Shi Hao Tan, Phuong Cao Thi Ngoc, Stella Amanda, Alice Wei Yee Yam, Wei‐Siang Liau, Zhiyuan Gong, Lee N. Lawton, Daniel Geoffrey Tenen, Takaomi Sanda · 2017 · Genes & Development