Activation of proto-oncogenes by disruption of chromosome neighborhoods

Hnisz, Denes, Weintraub, Abraham S., Day, Daniel S., Valton, Anne-Laure, Bak, Rasmus O., Li, Charles H., Goldmann, Johanna, Lajoie, Bryan R., Fan, Zi Peng, Sigova, Alla A., Reddy, Jessica, Borges-Rivera, Diego, Lee, Tong Ihn, Jaenisch, Rudolf, Porteus, Matthew H., Dekker, Job, Young, Richard A.·2016·Science
DOI 10.1126/science.aad9024

Cited by (999)

Items 201–300 of 999

  1. The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
    Moreau, Jean-Francois, Pradeu, Thomas, Grignolio, Andrea, Nardini, Christine, Castiglione, Filippo, Tieri, Paolo, Capri, Miriam, Salvioli, Stefano, Taupin, Jean-Luc, Garagnani, Paolo et al. · 2017 · Ageing Research Reviews
  2. The interdependence of gene-regulatory elements and the 3D genome
    Marit Willemijn Vermunt, Di Zhang, Gerd A. Blobel · 2018 · The Journal of Cell Biology
  3. Nonlinear control of transcription through enhancer-promoter interactions
    Zuin, Jessica, Roth, Gregory, Zhan, Yinxiu, Cramard, Julie, Redolfi, Josef, Piskadlo, Ewa, Mach, Pia, Kryzhanovska, Mariya, Tihanyi, Gergely, Kohler, Hubertus et al. · 2021
  4. A prostate cancer risk element functions as a repressive loop that regulates HOXA13
    Zhi-Fei Luo, S. Rhie, Fides D. Lay, P. Farnham · 2017 · Cell Reports
  5. A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary
    Rafael Galupa, Elphège Pierre Nora, Rebecca Worsley-Hunt, Christel Picard, Chris Gard, Joke Gerarda van Bemmel, Nicolas Servant, Yinxiu Zhan, Fatima El Marjou, Colin Johanneau et al. · 2019 · Molecular Cell
  6. A TAD Skeptic: Is 3D Genome Topology Conserved?
    Ittai E. Eres, Yoav Gilad · 2020 · Trends in Genetics
  7. SpectralTAD: an R package for defining a hierarchy of topologically associated domains using spectral clustering
    Kellen G. Cresswell, John C. Stansfield, Mikhail G. Dozmorov · 2020 · BMC Bioinformatics
  8. Three-dimensional folding dynamics of the Xenopus tropicalis genome
    Longjian Niu, Wei Shen, Zhaoying Shi, Yongjun Tan, Na He, Jing Wan, Jialei Sun, Yuedong Zhang, Yingzhang Huang, Wenjing Wang et al. · 2021 · Nature Genetics
  9. Applying CRISPR–Cas9 tools to identify and characterize transcriptional enhancers
    Rui Lopes, Gözde Korkmaz, Reuven Agami · 2016 · Nature Reviews Molecular Cell Biology
  10. DeepMILO: a deep learning approach to predict the impact of non-coding sequence variants on 3D chromatin structure
    Tuan Trieu, Alexander Martinez‐Fundichely, Ekta Khurana · 2020 · Genome biology
  11. Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression
    Erica S.M. Vos, Christian Valdes‐Quezada, Yike Huang, Amin Allahyar, Marjon J.A.M. Verstegen, Anna-Karina Felder, Floor van der Vegt, Esther C. H. Uijttewaal, Peter H.L. Krijger, Wouter L. de Laat · 2021 · Molecular Cell
  12. Multi-feature clustering of CTCF binding creates robustness for loop extrusion blocking and Topologically Associating Domain boundaries
    Li‐Hsin Chang, Sourav Ghosh, Andrea Papale, Jennifer M. Luppino, Mélanie Miranda, Vincent Piras, Jéril Degrouard, Joanne Edouard, Mallory Poncelet, Nathan Lecouvreur et al. · 2023 · Nature Communications
  13. When TADs go bad: Chromatin structure and nuclear organisation in human disease
    Kaiser, Vera B, Semple, Colin A · 2017 · F1000Research
  14. Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X
    Liu, Yu, Li, Chunliang, Shen, Shuhong, Chen, Xiaolong, Szlachta, Karol, Edmonson, Michael N., Shao, Ying, Ma, Xiaotu, Hyle, Judith, Wright, Shaela et al. · 2020 · Nature Genetics
  15. Telomere repeats induce domains of H3K27 methylation in Neurospora
    Kirsty Jamieson, Kevin J. McNaught, Tereza Ormsby, Neena A. Leggett, Shinji Honda, Eric U. Selker · 2018 · eLife
  16. LDB1 establishes multi-enhancer networks to regulate gene expression
    Aboreden, Nicholas G., Lam, Jessica C., Goel, Viraat Y., Wang, Siqing, Wang, Xiaokang, Midla, Susannah C., Quijano, Alma, Keller, Cheryl A., Giardine, Belinda M., Hardison, Ross C. et al. · 2025 · Molecular Cell
  17. Spatial Organization of Chromatin: Emergence of Chromatin Structure During Development
    Rajarshi P. Ghosh, Barbara J Meyer · 2021 · Annual Review of Cell and Developmental Biology
  18. An integrated view of the structure and function of the human 4D nucleome
    Job Dekker, Betül Akgöl Oksuz, Yang Zhang, Ye Wang, Miriam K. Minsk, Shuzhen Kuang, Liyan Yang, Johan Harmen Gibcus, Nils Krietenstein, Oliver J. Rando et al. · 2025 · Nature
  19. Heat Shock Protein Genes Undergo Dynamic Alteration in Their Three-Dimensional Structure and Genome Organization in Response to Thermal Stress
    Surabhi Chowdhary, Amoldeep S. Kainth, David S. Gross · 2017 · Molecular and Cellular Biology
  20. RAG Chromatin Scanning During V(D)J Recombination and Chromatin Loop Extrusion are Related Processes
    Sherry G. Lin, Zhaoqing Ba, Frederick W. Alt, Yu Zhang · 2018 · Advances in immunology
  21. Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm
    Sho Kubota, K. Tokunaga, Tomohiro Umezu, Takako Yokomizo-Nakano, Yuqi Sun, M. Oshima, K. Tan, Henry Yang, A. Kanai, Eisaku Iwanaga et al. · 2019 · Nature Communications
  22. Robust CTCF-Based Chromatin Architecture Underpins Epigenetic Changes in the Heart Failure Stress–Gene Response
    Dominic Paul Lee, Wilson Lek Wen Tan, Chukwuemeka George Anene-Nzelu, Chang Jie Mick Lee, Peter Yiqing Li, Tuan Danh Anh Luu, Cheryl Xueli Chan, Zenia Tiang, Shi Ling Ng, Xingfan Huang et al. · 2019 · Circulation
  23. Molecular markers in ALL: Clinical implications
    Shunsuke Kimura, Charles Grenfell Mullighan · 2020 · Best Practice & Research Clinical Haematology
  24. Super-enhancers in transcriptional regulation and genome organization
    Wang, Xi, Cairns, Murray J, Yan, Jian · 2019 · Nucleic Acids Research
  25. Higher-Order Chromosomal Structures Mediate Genome Function
    Ivana Jerković, Quentin Szabo, Frédéric Bantignies, Giacomo Cavalli · 2019 · Journal of Molecular Biology
  26. The multifaceted roles of cohesin in cancer
    Maddalena Di Nardo, Maria Michela Pallotta, Antonio Musio · 2022 · Journal of Experimental & Clinical Cancer Research
  27. Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline
    V. Kaiser, C. Semple · 2017 · Genome Biology
  28. Engineering 3D genome organization
    Haifeng Wang, Mengting Han, Lei S. Qi · 2021 · Nature Reviews Genetics
  29. The CCCTC‐binding factor (CTCF)–forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma
    Bin Zhang, Yajing Zhang, Xiaoping Zou, Anthony W.H. Chan, Rui Zhang, Terence K. Lee, Hang Liu, Eunice Yuen-Ting Lau, Nicole Pui Yu Ho, Paul B.S. Lai et al. · 2017 · The Journal of Pathology
  30. Chromatin Conformation in Development and Disease
    Ilias Boltsis, Frank G. Grosveld, Guillaume Giraud, Petros Kolovos · 2021 · Frontiers in Cell and Developmental Biology
  31. Chromatin topology and the timing of enhancer function at the HoxD locus
    Eddie Rodríguez-Carballo, Lucille Lopez‐Delisle, Andréa Willemin, Leonardo L Beccari, Sandra Gitto, Bénédicte Mascrez, Denis Duboule · 2020 · Proceedings of the National Academy of Sciences
  32. Crossed wires: 3D genome misfolding in human disease
    Norton, Heidi K., Phillips-Cremins, Jennifer E. · 2017 · Journal of Cell Biology
  33. Topologically Associating Domains and Regulatory Landscapes in Development, Evolution and Disease
    Juan J. Tena, José M. Santos-Pereira · 2021 · Frontiers in Cell and Developmental Biology
  34. The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer
    Susmita Gurjar Ramanand, Yong Chen, Jiapei Yuan, Kelly Daescu, Maryou B.K. Lambros, Kathleen E. Houlahan, Suzanne Carreira, Wei Yuan, GuemHee Baek, Adam Sharp et al. · 2020 · Journal of Clinical Investigation
  35. Pan-3D genome analysis reveals structural and functional differentiation of soybean genomes
    Lingbin Ni, Yu-Cheng Liu, Xin Ma, Teng-Fei Liu, Xiaoyue Yang, Zhao Wang, Qian-Jin Liang, Shu-Lin Liu, Min Zhang, Zheng Wang et al. · 2023 · Genome Biology
  36. Non-coding genetic variation in cancer
    Tawny N. Cuykendall, Mark A. Rubin, Ekta Khurana · 2017 · Current Opinion in Systems Biology
  37. Shaping Gene Expression by Landscaping Chromatin Architecture: Lessons from a Master
    Vittorio Sartorelli, Prem Puri · 2018 · Molecular Cell
  38. Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis
    Haruka Tsuchiya, Mineto Ota, Shuji Sumitomo, Kazuyoshi Ishigaki, Akari Suzuki, Toyonori Sakata, Yumi Tsuchida, Hiroshi Inui, Jun Hirose, Yuta Kochi et al. · 2020 · Annals of the Rheumatic Diseases
  39. ZNF143 is a regulator of chromatin loop
    Wen, Zi, Huang, Zhi-Tao, Zhang, Ran, Peng, Cheng · 2018 · Cell Biology and Toxicology
  40. Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 cases
    Yu-Ting Dai, Fan Zhang, Hai Fang, Jianfeng Li, Gang Lü, Lu Jiang, Bing Chen, Dongdong Mao, Yuanfang Liu, Jin Wang et al. · 2022 · Proceedings of the National Academy of Sciences
  41. 3D genome and its disorganization in diseases
    Ruifeng Li, Yuting Liu, Yingping Hou, Jingbo Gan, Pengze Wu, Li Cheng · 2018 · Cell Biology and Toxicology
  42. Three-dimensional organization and dynamics of the genome
    Przemysław Szałaj, Dariusz Plewczyński · 2018 · Cell Biology and Toxicology
  43. Three-dimensional genome organization in immune cell fate and function
    Sergi Cuartero, Grégoire Stik, Ralph Stadhouders · 2022 · Nature reviews. Immunology
  44. Constricted migration is associated with stable 3D genome structure differences in cancer cells
    Rosela Golloshi, Christopher Playter, Trevor F. Freeman, Priyojit Das, Thomas Isaac Raines, Joshua H. Garretson, Delaney Thurston, Rachel Patton McCord · 2022 · EMBO Reports
  45. Machine Learning for Nuclear Mechano-Morphometric Biomarkers in Cancer Diagnosis
    Adityanarayanan Radhakrishnan, Karthik Damodaran, Ali C. Soylemezoglu, Caroline Uhler, G. V. Shivashankar · 2017 · Scientific Reports
  46. Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation
    S. Rhie, S. Schreiner, Heather Witt, Chris Armoskus, Fides D. Lay, A. Camarena, Valeria N. Spitsyna, Yu Guo, Benjamin P. Berman, O. Evgrafov et al. · 2018 · Science Advances
  47. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells
    Yoshiki Higashijima, Yusuke Matsui, Teppei Shimamura, Ryo Nakaki, Nao Nagai, Shuichi Tsutsumi, Yohei Abe, Verena M. Link, Mizuko Osaka, Masayuki Yoshida et al. · 2020 · The EMBO Journal
  48. Integrated Analysis of Whole Genome and Epigenome Data Using Machine Learning Technology: Toward the Establishment of Precision Oncology
    Ken Asada, Syuzo Kaneko, Ken Takasawa, Hidenori Machino, Satoshi Takahashi, Norio Shinkai, Ryo Shimoyama, Masaaki Komatsu, Ryuji Hamamoto · 2021 · Frontiers in Oncology
  49. Super-Enhancers, Phase-Separated Condensates, and 3D Genome Organization in Cancer
    Seng Chuan Tang, Udhaya Vijayakumar, Ying Zhang, Melissa J. Fullwood · 2022 · Cancers
  50. Enhancer–promoter specificity in gene transcription: molecular mechanisms and disease associations
    Meyer J. Friedman, Tobias Wagner, Haram Lee, Michael G. Rosenfeld, Soohwan Oh · 2024 · Experimental & Molecular Medicine
  51. Selfish: discovery of differential chromatin interactions via a self-similarity measure
    Abbas Roayaei Ardakany, Ferhat Ay, Stefano Lonardi · 2019 · Bioinformatics
  52. Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles
    Benjamin I. Laufer, Hye‐Yeon Hwang, Julia M. Jianu, Charles E. Mordaunt, Ian F. Korf, Irva Hertz‐Picciotto, Janine M. LaSalle · 2020 · Human Molecular Genetics
  53. Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors
    Stuart R. Jefferys, Samuel D. Burgos, Jackson J. Peterson, Sara R. Selitsky, Anne‐Marie W. Turner, Lindsey Ingerman James, Yi‐Hsuan Tsai, Alisha R. Coffey, David M. Margolis, Joel S. Parker et al. · 2021 · PLoS Pathogens
  54. 3D chromatin architecture and epigenetic regulation in cancer stem cells
    Yuliang Feng, Xingguo Liu, Siim Pauklin · 2021 · Protein & Cell
  55. High-throughput Pore-C reveals the single-allele topology and cell type-specificity of 3D genome folding
    Jiayong Zhong, Longjian Niu, Zhuobin Lin, Xin Bai, Ying Chen, Feng Luo, Chunhui Hou, Chuan‐Le Xiao · 2023 · Nature Communications
  56. Noncoding copy-number variations are associated with congenital limb malformation
    Ricarda Flöttmann, Bjørt K. Kragesteen, Sinje Geuer, Magdalena Socha, Lila Allou, Anna Sowińska‐Seidler, Laure Bosquillon de Jarcy, Johannes Wagner, Aleksander Jamsheer, Barbara Oehl‐Jaschkowitz et al. · 2017 · Genetics in Medicine
  57. 1CPN: A coarse-grained multi-scale model of chromatin
    Joshua P. Lequieu, Andrés Córdoba, Joshua Moller, Juan Pablo · 2019 · The Journal of Chemical Physics
  58. Linking chromatin acylation mark-defined proteome and genome in living cells
    Fangfei Qin, Boyuan Li, Hui Wang, Sihui Ma, Jiaofeng Li, Shanglin Liu, Linghao Kong, Huangtao Zheng, Rongfeng Zhu, Yu Han et al. · 2023 · Cell
  59. CTCF enhances pancreatic cancer progression via FLG-AS1-dependent epigenetic regulation and macrophage polarization
    Yihao Liu, Pengyi Liu, Songqi Duan, Jiayu Lin, Wenxin Qi, Zhigang Yu, Xia Gao, Xiuqiao Sun, Jia Liu, Jiewei Lin et al. · 2024 · Cell Death and Differentiation
  60. Lingering Questions about Enhancer RNA and Enhancer Transcription-Coupled Genomic Instability
    Gerson Rothschild, Uttiya Basu · 2017 · Trends in Genetics
  61. TT‐seq captures enhancer landscapes immediately after T‐cell stimulation
    Margaux Michel, Carina Demel, Benedikt Zacher, Björn Schwalb, Stefan Krebs, Helmut Blum, Julien Gagneur, Patrick Cramer · 2017 · Molecular Systems Biology
  62. Spatial chromatin architecture alteration by structural variations in human genomes at the population scale
    Michał Sadowski, Agnieszka Kraft, Przemysław Szałaj, Michał Wlasnowolski, Zhonghui Tang, Yijun Ruan, Dariusz Plewczyński · 2019 · Genome biology
  63. The Role of Insulation in Patterning Gene Expression
    Isa Özdemir, Maria Cristina Gambetta · 2019 · Genes
  64. Alteration of genome folding via contact domain boundary insertion
    Di Zhang, Peng Huang, Malini Sharma, Cheryl A. Keller, Belinda M. Giardine, Haoyue Zhang, Thomas G. Gilgenast, Jennifer E. Phillips‐Cremins, Ross C. Hardison, Gerd A. Blobel · 2020 · Nature Genetics
  65. 3D genome evolution and reorganization in the Drosophila melanogaster species group
    Nicole S. Torosin, Aparna Anand, Tirupathi Rao Golla, Weihuan Cao, Christopher E. Ellison · 2020 · PLoS Genetics
  66. The role of insulators and transcription in 3D chromatin organization of flies
    Keerthi T. Chathoth, Liudmila A Mikheeva, Gilles Crevel, Jareth C. Wolfe, Ioni Hunter, Saskia Beckett-Doyle, Sue Cotterill, Hongsheng Dai, Andrew Harrison, Nicolae Radu Zabet · 2022 · Genome Research
  67. Computational Prediction of Position Effects of Apparently Balanced Human Chromosomal Rearrangements
    Cinthya J. Zepeda‐Mendoza, Jonas Ibn-Salem, Tammy Kammin, David J. Harris, Debra Rita, Karen Webster Gripp, Jennifer J. MacKenzie, Andrea Lynne Gropman, Brett H. Graham, Ranad Shaheen et al. · 2017 · The American Journal of Human Genetics
  68. Copy number alterations unmasked as enhancer hijackers
    Beroukhim, Rameen, Zhang, Xiaoyang, Meyerson, Matthew · 2017 · Nature Genetics
  69. Comparative characterization of 3D chromatin organization in triple-negative breast cancers
    Taemook Kim, Sungwook Han, Yujin Chun, Hyeok-Jun Yang, Hyesung Min, Sook Young Jeon, Jang‐il Kim, Hyeong‐Gon Moon, Daeyoup Lee · 2022 · Experimental & Molecular Medicine
  70. Convergent epigenetic evolution drives relapse in acute myeloid leukemia
    Kevin A. Nuno, Armon Azizi, Thomas Köhnke, Caleb A. Lareau, Asiri Ediriwickrema, M. Ryan Corces, Ansuman T. Satpathy, Ravindra Majeti · 2024 · eLife
  71. Chromatin topology in development and disease
    Olimpia Bompadre, Guillaume Andrey · 2019 · Current Opinion in Genetics & Development
  72. HiPiler: Visual Exploration of Large Genome Interaction Matrices with Interactive Small Multiples
    Fritz Lekschas, Benjamin Bach, Peter Kerpedjiev, Nils Gehlenborg, Hanspeter Pfister · 2017 · IEEE Transactions on Visualization and Computer Graphics
  73. Runx Transcription Factors in T Cells—What Is Beyond Thymic Development?
    Svetlana Korinfskaya, Sreeja Parameswaran, Matthew T. Weirauch, Artem Barski · 2021 · Frontiers in Immunology
  74. A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells
    Lei Guo, Jia Li, Hongxiang Zeng, Anna G. Guzman, Tingting Li, Minjung Lee, Yubin Zhou, Margaret A. Goodell, CLIFFORD C. STEPHAN, Peter J. Davies et al. · 2020 · Nature Communications
  75. Machine Learning in Epigenomics: Insights into Cancer Biology and Medicine
    Emre Arslan, Jonathan Schulz, Kunal Rai · 2021 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  76. Bidirectional epigenetic editing reveals hierarchies in gene regulation
    Naomi M. Pacalin, Zachary Steinhart, Quanming Shi, Julia A. Belk, Dmytro Dorovskyi, Katerina Kraft, Kevin R. Parker, Brian Rudolph Shy, Alexander Marson, Howard Y. Chang · 2024 · Nature Biotechnology
  77. Epigenetic regulation of neuroblastoma development
    Kaat Durinck, Frank Speleman · 2018 · Cell and Tissue Research
  78. A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
    Yiqun Zhang, Fengju Chen, Lawrence A. Donehower, Michael E. Scheurer, Chad J. Creighton · 2021 · Nature Communications
  79. Ectopic Expression of Testis Germ Cell Proteins in Cancer and Its Potential Role in Genomic Instability
    Aaraby Nielsen, Morten F. Gjerstorff · 2016 · International Journal of Molecular Sciences
  80. Disruption of the 3D Cancer Genome Blueprint
    Joanna Achinger-Kawecka, Susan J. Clark · 2016 · Epigenomics
  81. Aberrant activation of the GIMAP enhancer by oncogenic transcription factors in T-cell acute lymphoblastic leukemia
    Wei‐Siang Liau, Shi Hao Tan, Phuong Cao Thi Ngoc, Chelsia Qiuxia Wang, Vinay Tergaonkar, Hui Feng, Zhiyuan Gong, Motomi Osato, Alfred Thomas Look, Takaomi Sanda · 2016 · Leukemia
  82. Enhancer dysfunction in leukemia
    Anand S. Bhagwat, Bin Lu, Christopher R. Vakoc · 2018 · Blood
  83. Mutational Patterns in Metastatic Cutaneous Squamous Cell Carcinoma
    Simon Andreas Mueller, Marie-Emilie A. Gauthier, Bruce Ashford, Ruta Gupta, Velimir Gayevskiy, Sydney Ch’ng, Carsten Erich Palme, Kerwin Frank Shannon, Jonathan Robert Clark, Marie Ranson et al. · 2019 · Journal of Investigative Dermatology
  84. In situ dissection of domain boundaries affect genome topology and gene transcription in Drosophila
    Rodrigo G. Arzate-Mejía, Angel Josué Cerecedo-Castillo, G. Guerrero, M. Furlan-Magaril, F. Recillas-Targa · 2019 · Nature Communications
  85. Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells
    Sarah G. Swygert, Dejun Lin, Stephanie Portillo‐Ledesma, Po-Yen Lin, Dakota R. Hunt, Cheng-Fu Kao, Tamar Schlick A, William Stafford Noble, Toshio Tsukiyama · 2021 · eLife
  86. A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer
    Yanli Liu, Zhong Wu, Jin Rong Zhou, Dinesh K. A. Ramadurai, Katelyn L. Mortenson, Estrella Aguilera-Jimenez, Yifei Yan, Xiaojun Yang, Alison Marie Taylor, Katherine Elena Varley et al. · 2021 · Nature Communications
  87. The role of 3D genome organization in disease: From compartments to single nucleotides
    Abhijit Chakraborty, Ferhat Ay · 2018 · Seminars in Cell and Developmental Biology
  88. Evolution of weak cooperative interactions for biological specificity
    Ang Gao, Krishna Shrinivas, Paul Lepeudry, Hiroshi I. Suzuki, Phillip A. Sharp, Arup K. Chakraborty · 2018 · Proceedings of the National Academy of Sciences
  89. Chromosome structural variation in tumorigenesis: mechanisms of formation and carcinogenesis
    Wenjun Wang, Lingyu Li, Jiuwei Cui · 2020 · Epigenetics & Chromatin
  90. Human papillomavirus integration transforms chromatin to drive oncogenesis
    Mehran Karimzadeh, Christopher Arlidge, Ariana Rostami, Mathieu Lupien, Scott Victor Bratman, Michael M. Hoffman · 2023 · Genome biology
  91. Mechanisms of sex determination and X-chromosome dosage compensation
    Barbara J Meyer · 2022 · Genetics
  92. Spatial Genome Organization and Its Emerging Role as a Potential Diagnosis Tool
    Karen J. Meaburn · 2016 · Frontiers in Genetics
  93. Kilobase Pair Chromatin Fiber Contacts Promoted by Living-System-Like DNA Linker Length Distributions and Nucleosome Depletion
    Gavin D. Bascom, Tae‐Jin Kim, Tamar Schlick A · 2017 · The Journal of Physical Chemistry B
  94. Risk variants disrupting enhancers of T H 1 and T REG cells in type 1 diabetes
    Peng Gao, Yasin Uzun, Bing He, Sara Salamati, Julie Coffey, Eva Tsalikian, Kai Tan · 2019 · Proceedings of the National Academy of Sciences
  95. An Epigenetic Perspective on Intra-Tumour Heterogeneity: Novel Insights and New Challenges from Multiple Fields
    Sven Beyes, Naiara G. Bediaga, Alessio Zippo · 2021 · Cancers
  96. 3DIV update for 2021: a comprehensive resource of 3D genome and 3D cancer genome
    Kyukwang Kim, Insu Jang, Mooyoung Kim, Jinhyuk Choi, Min-Seo Kim, Byung-Wook Lee, Inkyung Jung · 2020 · Nucleic Acids Research
  97. Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia
    Leonie Smeenk, Sophie Ottema, Roger Mulet‐Lazaro, Anja Ebert, Marije Havermans, Andrea Arricibita Varea, Michaela Fellner, Dorien Pastoors, Stanley van Herk, Claudia A. J. Erpelinck-Verschueren et al. · 2021 · Cancer Discovery
  98. The Stochastic Genome and Its Role in Gene Expression
    Christopher H. Bohrer, Daniel R. Larson · 2021 · Cold Spring Harbor Perspectives in Biology
  99. Non-coding RNAs and chromatin domains
    Tatsuro Yamamoto, Noriko Saitoh · 2019 · Current Opinion in Cell Biology
  100. Coarse-Grained Models to Study Protein–DNA Interactions and Liquid–Liquid Phase Separation
    Utkarsh Kapoor, Y. C. Kim, J. Mittal · 2023 · Journal of Chemical Theory and Computation