NAD + repletion improves mitochondrial and stem cell function and enhances life span in mice

Zhang, Hongbo, Ryu, Dongryeol, Wu, Yibo, Gariani, Karim, Wang, Xu, Luan, Peiling, D’Amico, Davide, Ropelle, Eduardo R. +5 more·2016·Science
DOI 10.1126/science.aaf2693

Cited by (1,000)

Items 801–900 of 1,000

  1. Nanomaterials intervene in cell senescence to reinforce cancer therapy
    Shumin Sun, Nailin Yang, Jihu Nie, Zixian Yang, Zifan Pei, Rong Ding, Liang Cheng · 2025 · Coordination Chemistry Reviews
  2. Synthesis, Stability, and Bioavailability of Nicotinamide Riboside Trioleate Chloride
    Amin Zarei, Leila Khazdooz, Sara Madarshahian, Mojtaba Enayati, Imann Mosleh, Tiantian Lin, Bing Yan, Gerhard Ufheil, Tim J. Wooster, Alireza Abbaspourrad · 2021 · Nutrients
  3. Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications
    Priyanka Banerjee, Elizabeth A. Olmsted‐Davis, Anita M Deswal, Minh Tho Ho Nguyen, Efstratios Koutroumpakis, Nicholas Palaskas, Steven Hsesheng Lin, Sivareddy Kotla, Cielito C. Reyes‐Gibby, Sai‐Ching J. Yeung et al. · 2022 · The Journal of Cardiovascular Aging
  4. We are all aging, and here's why
    Atharva Shinde, Gargi Deore, Kedar P. Navsariwala, Heena Tabassum, Minal Wani · 2022 · Aging Medicine
  5. The emerging importance of NAD+ metabolome for nutrition and food sciences: A bibliometric analysis
    Gabriela Fabiana Soares Alegre, Gláucia María Pastore · 2023 · Food Bioscience
  6. Nicotinamide Riboside Derivatives: Single Crystal Growth and Determination of X-ray Structures
    Ricardo Alvarez, Günter Schabert, Aysel Soydemir, Lukas Wick, Urs P. Spitz, Bernhard Spingler · 2019 · Crystal Growth & Design
  7. Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction
    Craig L. Doig, Agnieszka E. Zielinska, Rachel S. Fletcher, Lucy A. Oakey, Yasir Elhassan, Antje Garten, David Cartwright, Silke Heising, Ahmed Alsheri, David George Watson et al. · 2020 · Skeletal Muscle
  8. Opportunities and Challenges in Stem Cell Aging
    Bagher A. Larijani, Najmeh Foroughi Heravani, Setareh Alaei, Mostafa Rezaei–Tavirani, Sepideh Alavi-Moghadam, Moloud Payab, Parisa Goodarzi, Akram Tayanloo-Beik, Hamid Reza Aghayan, Babak Arjmand · 2021 · Advances in experimental medicine and biology
  9. PGC-1α in the myofibers regulates the balance between myogenic and adipogenic progenitors affecting muscle regeneration
    Marc Beltrà, Fabrizio Pin, Domiziana Costamagna, Robin Duelen, Alessandra Renzini, Riccardo Ballarò, Lorena Garcia‐Castillo, Ambra Iannuzzi, Viviana Moresi, Dario Coletti et al. · 2022 · iScience
  10. Quaternary structure of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) controls its activity
    Yu Yang, Ian Davis, Tsutomu Matsui, Ivan P. Rubalcava, Aimin Liu · 2019 · Journal of Biological Chemistry
  11. The Long-Term Impairment in Redox Homeostasis Observed in the Hippocampus of Rats Subjected to Global Perinatal Asphyxia (PA) Implies Changes in Glutathione-Dependent Antioxidant Enzymes and TIGAR-Dependent Shift Towards the Pentose Phosphate Pathways: Effect of Nicotinamide
    Carolyne Lespay‐Rebolledo, Andrea Tapia-Bustos, Diego Bustamante, Paola Morales, Mario Herrera‐Marschitz · 2019 · Neurotoxicity Research
  12. Inherited myogenic abilities in muscle precursor cells defined by the mitochondrial complex I-encoding protein
    Norio Motohashi, Katsura Minegishi, Yoshitsugu Aoki · 2023 · Cell Death and Disease
  13. Resetting the aging clock through epigenetic reprogramming: Insights from natural products
    Xin Liu, Jing Hai Feng, Madi Guo, Chen Chen, Tong Zhao, Xiuxiu Sun, Yong Zhang · 2025 · Pharmacology & Therapeutics
  14. Cellular senescence in age-related musculoskeletal diseases
    Jinming Xiong, Qiaoyue Guo, Xianghang Luo · 2025 · Frontiers of Medicine
  15. SRT1720 Pretreatment Promotes Mitochondrial Biogenesis of Aged Human Mesenchymal Stem Cells and Improves Their Engraftment in Postinfarct Nonhuman Primate Hearts
    Zhiru Zeng, Kaixiang Yu, Wangxing Hu, Si Cheng, Chenyang Gao, Feng Liu, Jinyong Chen, Minjian Kong, Fengjiang Zhang, Xianbao Liu et al. · 2021 · Stem Cells and Development
  16. Potential Therapeutic Interventions Targeting NAD+ Metabolism for ALS
    Samuel Lundt, Shinghua Ding · 2024 · Cells
  17. Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging
    Xiao Tian, Andrei Seluanov, Vera A. Gorbunova · 2017 · Cell Metabolism
  18. NAD+: A big player in cardiac and skeletal muscle remodeling and aging
    Pankaj Chaturvedi, Suresh C. Tyagi · 2017 · Journal of Cellular Physiology
  19. Small-molecule nicotinamide for ex vivo expansion of umbilical cord blood
    Prioty Islam, Mitchell E. Horwitz · 2019 · Experimental Hematology
  20. The therapeutic promises of NAD+ boosters
    Claudia Montllor-Albalate, Zehan Song, Danica Chen · 2021 · Cell Metabolism
  21. Identification of CD157-Positive Vascular Endothelial Stem Cells in Mouse Retinal and Choroidal Vessels: Fluorescence-Activated Cell Sorting Analysis
    Taku Wakabayashi, Hisamichi Naito, Tomohiro Iba, Kohji Nishida, Nobuyuki Takakura · 2022 · Investigative Ophthalmology & Visual Science
  22. Skeletal muscle mitochondrial dysfunction in contemporary antiretroviral therapy: a single cell analysis
    Matthew Hunt, Megan M. McNiff, Amy E. Vincent, Caroline Anne Sabin, Alan Winston, Brendan A. I. Payne · 2022 · AIDS
  23. Gene network analysis of senescence-associated genes in annual plants and comparative assessment of aging in perennials and animals
    Hou‐Ling Wang, Hongwei Guo, Zhonghai Li · 2019 · Translational Medicine of Aging
  24. Pharmacological inhibition of guanosine triphosphate cyclohydrolase1 elevates tyrosine phosphorylation of caveolin1 and cellular senescence
    Soniya Charles, V. Samuel Raj, Mohankumar Ramasamy, Kaliappan Ilango, Jesu Arockiaraj, Murugesan Sakthivadivel, Kanchana Mala · 2019 · European Journal of Pharmacology
  25. Production of liposome loaded with nicotinamide mononucleotide using Taylor-Couette reactor
    Beom Soo Kim, Beom Soo Kim · 2024 · Chemical Engineering Journal
  26. CD38 mediates nicotinamide mononucleotide base exchange to yield nicotinic acid mononucleotide
    Romanthi J. Madawala, Jasmine L. Banks, Sarah E. Hancock, Lake‐Ee Quek, Nigel A. Turner, Lindsay E. Wu · 2025 · Journal of Biological Chemistry
  27. Metabolomics Analysis Reveals Characteristic Functional Components in Pigeon Eggs
    Rui Zhang, Lingling Chang, Xinyue Shen, Qingping Tang, Chunyu Mu, Shengyong Fu, Zhu Bu · 2025 · Metabolites
  28. Oxidant-Based Cytotoxic Agents During Aging: From Disturbed Energy Metabolism to Chronic Inflammation and Disease Progression
    Jürgen Arnhold · 2025 · Biomolecules
  29. Mitochondrial homeostasis in stem cell senescence
    Baozhou Peng, Hongbo Zhang · 2025 · Oral Science and Homeostatic Medicine
  30. The NAD-brain pharmacokinetic study of NAD augmentation in blood and brain using oral precursor supplementation
    Haakon Berven, Magnus Svensen, Heidi Eikeland, Nora Tvedten, Erika Sheard, Solveig Amdahl Af Geijerstam, Mona Søgnen, Adrian McCann, Lena Arnsten, Ove Arseth et al. · 2026 · iScience
  31. Dihydronicotinamide riboside: synthesis from nicotinamide riboside chloride, purification and stability studies
    Amin Zarei, Leila Khazdooz, Mojtaba Enayati, Sara Madarshahian, Tim J. Wooster, Gerhard Ufheil, Alireza Abbaspourrad · 2021 · RSC Advances
  32. Topical Application of Galgeunhwanggeumhwangryeon-Tang Recovers Skin-Lipid Barrier and Ameliorates Inflammation via Filaggrin-Thymic Stromal Lymphopoietin-Interleukin 4 Pathway
    Sang Hyun Ahn, Su M. Shin, Yoonju Do, Yunju Jo, Dongryeol Ryu, Ki‐Tae Ha, Ki Bong Kim · 2021 · Medicina
  33. Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs
    Ece Yıldız, Gaby El Alam, Alessia Perino, Antoine Jalil, Pierre‐Damien Denechaud, Katharina Huber, Lluís Fajas, Johan H. Auwerx, Giovanni Sorrentino, Kristina Schoonjans · 2022 · eLife
  34. The role of the stem cell epigenome in normal aging and rejuvenative therapy
    Jeyan Jayarajan, Michael D. Milsom · 2020 · Human Molecular Genetics
  35. The Many Roles Mitochondria Play in Mammalian Aging
    Caio M.P.F. Batalha, Aníbal Eugênio Vercesi, Nadja Cristhina de Souza-Pinto · 2021 · Antioxidants and Redox Signaling
  36. Effects of short-term endurance and strength exercise in the molecular regulation of skeletal muscle in hyperinsulinemic and hyperglycemic Slc2a4+/− mice
    Vítor Rosetto Muñoz, José Diego Botezelli, Rafael Calais Gaspar, Alisson Luiz da Rocha, Renan Fudoli Lins Vieira, Bárbara Crisol, Renata Rosseto Braga, Matheus Brandemarte Severino, Susana Castelo Branco Ramos Nakandakari, Gabriel Calheiros Antunes et al. · 2023 · Cellular and Molecular Life Sciences
  37. The yin and yang of mitochondrial dysfunction
    Kim Baumann · 2016 · Nature Reviews Molecular Cell Biology
  38. Transplantation of Muscle Stem Cell Mitochondria Rejuvenates the Bioenergetic Function of Dystrophic Muscle
    Mahir Mohiuddin, Jeongmoon J. Choi, Nan Hee Lee, Hyeonsoo Jeong, Shannon E. Anderson, Woojin M. Han, Berna Aliya, Tsvetomira Z. Peykova, Sumit Verma, Andrés J. Garcı́a et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  39. Human skeletal muscle ageing atlas
    Veronika R. Kedlian, Yaning Wang, Tianliang Liu, Xiaoping Chen, Liam Bolt, Zhuojian Shen, Eirini Sofia Fasouli, Elena Prigmore, Vitalii Kleshchevnikov, Tong Li et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  40. NAD+-Consuming Enzymes in Stem Cell Homeostasis
    Xiuna Ji, Mingyue Zheng, Tao Yu, Jie Kang, Ting‐Jun Fan, Bin Xu · 2023 · Oxidative Medicine and Cellular Longevity
  41. Intestinal lysozyme1 deficiency alters microbiota composition and impacts host metabolism through the emergence of NAD + -secreting ASTB Qing110 bacteria
    C.L. Zhang, Xiang Chen, Kaichen Zhou, Xingchen Liu, Guofeng Qiao, Yabo Zhao, Kemeng Dong, Ke Sun, Zhihua Liu · 2024 · mSystems
  42. Supplementation with NAD+ and its precursors: A rescue of female reproductive diseases
    Lan Li, Xin Zhou, Wene Liu, Zhen Chen, Xiaoqin Xiao, Guiming Deng · 2024 · Biochemistry and Biophysics Reports
  43. Identification of novel biomarkers and drug targets for frailty-related skeletal muscle aging: a multi-omics study
    Qijun Wang, Xuan Zhao, Wei Wang, Xiaolong Chen, Shibao Lu · 2025 · QJM
  44. Progress in anti-ageing drug research for age-related diseases: A review
    Ziying Zhou, Hao-tian Duan, Si-Tu Xue, Zhuorong Li · 2025 · Ageing Research Reviews
  45. Mechanisms of Impaired Skeletal Muscle Regeneration and Therapeutic Approaches in Aging and Chronic Disease
    Xia Li, Zihao Zhao, Jiawen Yang, Yijie Zhang, Xinlei Yao, Hualin Sun, Yuntian Shen · 2026 · Pharmaceuticals
  46. Vitamin combination promotes ex vivo expansion of NK-92 cells by reprogramming glucose metabolism
    Yan Fu, Yuying Chen, Zhepei Xie, Huimin Huang, Wen‐Song Tan, Haibo Cai · 2022 · Bioresources and Bioprocessing
  47. Protectin DX as a therapeutic strategy against frailty in mice
    Laís R. Perazza, Adam C. Gower, Holly M. Brown‐Borg, Paola Divieti Pajevic, LaDora V. Thompson · 2023 · GeroScience
  48. Therapeutic approaches for chronic hepatitis C: a concise review
    Allah Nawaz, Azhar Manzoor, Saeed Ahmed, Naveed Ahmed, Waseem Abbas, Mushtaq Ahmad Mir, Muhammad Bilal, Alisha Sheikh, Saleem Ahmad, Ishtiaq Jeelani et al. · 2024 · Frontiers in Pharmacology
  49. Muscle Psn gene combined with exercise contribute to healthy aging of skeletal muscle and lifespan by adaptively regulating Sirt1/PGC-1α and arm pathway
    Ying‐hui Gao, Deng‐tai Wen, Zhong-rui Du, Jingfeng Wang, Shijie Wang · 2024 · PLoS ONE
  50. Inhibition of poly(ADP-Ribosyl)ation reduced vascular smooth muscle cells loss and improves aortic disease in a mouse model of human accelerated aging syndrome
    Déborah Cardoso, Solenn M. Guilbert, Philippe Guigue, Aurélie Carabalona, Karim Harhouri, Cécile Peccate, Johana Tournois, Zoheir Guesmia, Lino Ferreira, Catherine Bartoli et al. · 2024 · Cell Death and Disease
  51. The role of CYP-sEH derived lipid mediators in regulating mitochondrial biology and cellular senescence: implications for the aging heart
    Ala Yousef, Liye Fang, Mobina Heidari, Joshua W. Kranrod, John M. Seubert · 2024 · Frontiers in Pharmacology
  52. Characterisation of the Plasma and Faecal Metabolomes in Participants with Functional Gastrointestinal Disorders
    Karl Fraser, Shanalee C. James, Wayne Young, Richard Blair Gearry, Phoebe E. Heenan, Jacqueline Ilene Keenan, Nicholas Joseph Talley, Warren Charles McNabb, Nicole Clemence Roy · 2024 · International Journal of Molecular Sciences
  53. Nicotinamide riboside–amino acid conjugates that are stable to purine nucleoside phosphorylase
    Faisal Hayat, Marie E. Migaud · 2020 · Organic & Biomolecular Chemistry
  54. Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock
    Carrie A. Sims, Hanna E. Labiner, Sohini S. Shah, Joseph A. Baur · 2021 · GeroScience
  55. Nicotinamide effects on the metabolism of human fibroblasts and keratinocytes assessed by quantitative, label-free fluorescence imaging
    Zhiyi Liu, C.‐Y. Chiang, John Nip, Lin Feng, Yang Zhang, Sheila Rocha, Irene Georgakoudi · 2021 · Biomedical Optics Express
  56. Mitochondrial‐Targeting Vitamin B3 Ameliorates the Phenotypes of Parkinson's Disease In Vitro and In Vivo by Restoring Mitochondrial Function
    Chenqi Xin, Naidi Yang, Yaqi Ding, Linqi Han, Zhiqiang Zhou, Xiaolu Guo, Zhijie Fang, Hua Bai, Bo Peng, Chengwu Zhang et al. · 2022 · Advanced Therapeutics
  57. CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice
    Jongsu Jeon, Dohyun Lee, Bobae Kim, Bo-Yoon Park, Chang Joo Oh, Minji Kim, Jae‐Han Jeon, In‐Kyu Lee, Onyu Park, Seoyeong Baek et al. · 2023 · Diabetes & Metabolism Journal
  58. Senescent Stem Cell Dysfunction and Age-Related Diseases
    Tongpeng Yue, Deguan Li · 2023 · Stem Cells and Development
  59. Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
    Jooyeon Suh, Hyeonkyeong Kim, Jiyun Min, Hyun Ju Yeon, Martin Hemberg, Luca Scimeca, Ming-Ru Wu, Hyun Guy Kang, Yi‐Jun Kim, Jin‐Hong Kim · 2023 · Cell Reports Medicine
  60. Yin and Yang: Why did evolution implement and preserve the circadian rhythmicity?
    Borut Poljšak, Samo Ribarič, Irina Milisav · 2019 · Medical Hypotheses
  61. Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice
    Megha Oza, William Becker, Phani M. Gummadidala, Travis Dias, Mayomi H. Omebeyinje, Li Chen, Chandrani Mitra, Rubaiya Jesmin, Paramita Chakraborty, Mathew Sajish et al. · 2019 · Scientific Reports
  62. Hexose Potentiates Peptide-Conjugated Morpholino Oligomer Efficacy in Cardiac Muscles of Dystrophic Mice in an Age-Dependent Manner
    Gang Han, Ben Gu, Caorui Lin, Hanhan Ning, Jun Song, Xianjun Gao, Hong M. Moulton, HaiFang Yin · 2019 · Molecular Therapy — Nucleic Acids
  63. Metabolic Regulation and Related Molecular Mechanisms in Various Stem Cell Functions
    Hwa‐Yong Lee, In‐Sun Hong · 2020 · Current Stem Cell Research & Therapy
  64. Cell Culture Studies: A Promising Approach to the Metabolomic Study of Human Aging
    Ana Rocha, Sandra Magalhães, Alexandra Nunes · 2021 · Current Metabolomics and Systems Biology
  65. Nutritional Mediators of Cellular Decline and Mitochondrial Dysfunction in Older Adults
    Jack M. Guralnik, Jérôme N. Feige, Anurag Singh, Roger A. Fielding · 2021 · Geriatrics
  66. High Glycolytic Activity Enhances Stem Cell Reprogramming of Fahd1-KO Mouse Embryonic Fibroblasts
    Ahmad Salti, Solmaz Etemad, Marta Suarez Cubero, Eva Albertini, Beata Kovacs-Szalka, Max Holzknecht, Elia Cappuccio, Maria Silvia Cavinato, Frank Edenhofer, Pidder Jansen‐Dürr · 2021 · Cells
  67. Randomized, placebo-controlled, pilot clinical study evaluating acute Niagen®+ IV and NAD+ IV in healthy adults
    Jessie Hawkins, Rebecca Idoine, Jun Kwon, Andrew E. Shao, Elizabeth Dunne, Elizabeth M. Hawkins, Kayla Dawson, Yasmeen M. Nkrumah-Elie · 2024 · medRxiv
  68. Metabolic Changes in Cardiac Aging
    Yan Hao, Wei Liu · 2023 · Reviews in Cardiovascular Medicine
  69. Pyridine-based small molecule inhibitors of SARM1 alleviate cell death caused by NADase activity
    Qingxuan Tang, Hang Hubert Yin · 2024 · Chemical Communications
  70. Navigating the Complex Pathogenesis of Acute Kidney Injury: Exploring Macrophage Dynamics, Mitochondrial Dysfunction, and Ferroptosis Pathways
    Tanima Chatterjee, Abolfazl Zarjou · 2025 · Advances in Kidney Disease and Health
  71. The Crucial Role of NAD+ in Mitochondrial Metabolic Regulation
    Kumudesh Mishra, Or Kakhlon · 2025 · Biocell
  72. Oral nicotinamide mononucleotide (NMN) increases tissue NAD+ content in mice but neither NMN nor Polypodium leucotomos protect against UVR-induced skin cancer
    Celina Pihl, Ravin Kara, Jonatan Riber Granborg, Uffe H. Olesen, Peter Bjerring, Merete Hædersdal, Gavrielle Rebecca Untracht, Catharina Margrethe Lerche · 2025 · Photochemical & Photobiological Sciences
  73. Senescent Polarization of Macrophages and Inflammatory Biomarkers in Cardiovascular Disease
    Alojz Ihan · 2025 · Cells
  74. Skeletal Muscle Aging: Enhancing Skeletal Muscle Integrity and Function as a Potential Pharmacological Approach
    Sibhghatulla Shaikh, Khurshid Ahmad, Jeong Ho Lim, Syed Sayeed Ahmad, Eun Ju Lee, Inho Choi · 2025 · Pharmaceuticals
  75. Metabolic regulation in the senescence process of stem cells
    Yingying Wei, Bin Zhang, Qingli Bie, Baoyu He · 2025 · Stem Cells Translational Medicine
  76. Targeting Sarcopenia as an Objective Clinical Outcome in the Care of Children with Spinal Cord-Related Paralysis: A Clinician’s View
    Cristina Lavinia Sadowsky · 2023 · Children
  77. Transcranial Electromagnetic Wave Treatment: A Fountain of Healthy Longevity?
    Gary W. Arendash, Chuanhai Cao · 2023 · International Journal of Molecular Sciences
  78. Effect of Nicotinamide Riboside Against the Exhaustion of CD8+ T Cells via Alleviating Mitochondrial Dysfunction
    Ying Xiao, Nengzhi Pang, Sixi Ma, Mengqi Gao, Lili Yang · 2024 · Nutrients
  79. A new cross-linked enzyme aggregate biocatalyst for NAD + -booster production
    Ana Belén Martínez-Moñino, Ruben Zapata Perez, Antonio Ginés García-Saura, Juana Cabanes, Álvaro Sánchez‐Ferrer · 2017 · RSC Advances
  80. Advances in pharmacological interventions of aging in mice
    Minxian Qian, Baohua Liu · 2019 · Translational Medicine of Aging
  81. New Crystalline Salts of Nicotinamide Riboside as Food Additives
    Günter Schabert, Robert G. Haase, Jaclyn Parris, Laura Pala, Adrian Hery-Barranco, Bernhard Spingler, Urs P. Spitz · 2021 · Molecules
  82. Thyroid hormone regulation of adult hippocampal neurogenesis: Putative molecular and cellular mechanisms
    Darshana Kapri, Sashaina E. Fanibunda, Vidita A. Vaidya · 2022 · Vitamins and hormones
  83. Differentially disrupted spinal cord and muscle energy metabolism in spinal and bulbar muscular atrophy
    Danielle DeBartolo, Frederick J. Arnold, Yuhong Liu, Elana Molotsky, Hsin‐Yao Tang, Diane E. Merry · 2024 · JCI Insight
  84. Nicotinamide ribose ameliorates myocardial ischemia/reperfusion injury by regulating autophagy and regulating oxidative stress
    Chen Yuan, Heng Yang, Wanqi Lan, Juesheng Yang, Yanhua Tang · 2024 · Experimental and Therapeutic Medicine
  85. Prevention of Senescence in Vasculature Through Quiescence
    Andrew R. Mendelsohn, James W. Larrick · 2018 · Rejuvenation Research
  86. Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization
    Kevin Kiesworo, Michael Robert MacArthur, Peter Kip, Thomas Agius, Diane Macabrey, Martine Lambelet, Lauriane Hamard, Charles Keith Ozaki, James R. Mitchell, Sébastien Déglise et al. · 2023 · JVS Vascular Science
  87. IMMP2L: a mitochondrial protease suppressing cellular senescence
    Valentina Sica, Guido Kroemer · 2018 · Cell Research
  88. Skeletal Muscle Stem Cells
    Nora Deniz Yucel, Helen M. Blau · 2018 · Elsevier eBooks
  89. Targeting enzyme aging
    Friedrich Reinhard Becker, K. Lenhard Rudolph · 2021 · Science
  90. A metabolic constraint in the kynurenine pathway drives mucosal inflammation in IBD
    Lina Welz, Danielle M M Harris, Na‐Mi Kim, Abrar I. Alsaadi, Qicong Wu, Mhmd Oumari, Jan Taubenheim, Valery Volk, Graziella Credido, Eric Koncina et al. · 2024 · medRxiv
  91. Metabolomics biomarkers of frailty: a longitudinal study of aging female and male mice
    Dantong Zhu, Judy Z. Wu, Patrick T. Griffin, Brady A. Samuelson, David A. Sinclair, Alice E. Kane · 2025 · npj Aging
  92. A Targeting Senescence and Recycling Intracellular Nicotinamide Adenine Dinucleotide Strategy for Attenuation of Senescence-Associated Phenotypes
    Jian Li, Mingjie Rong, Chen Liu, Lehui Lu · 2025 · ACS Nano
  93. Tryptophan metabolism in inter-organ communication and its potential applications for disease prevention and control
    Xiongzhuo Tang, Jianmin Wu, Zhenguo Hu, Mengxuan Tang, Feiyue Chen, Yuezhou Yao, Guijie Chen, Xiong Xiong, Bozhuang Zhou, Yi‐Zhou Gao et al. · 2025 · The Innovation Life
  94. Changes in the brain [NAD+]/[NADH] and [NADPH]/[NADP+] with aging and anti-aging dietary restriction
    Leah E. Jamerson, Tara Bradshaw, Patrick C. Bradshaw · 2026 · Frontiers in Aging Neuroscience
  95. NAD⁺ as a central metabolic hub Regulating the hallmarks of aging: Mechanisms and therapeutic implications
    Zerong Pei, Fengni Liang, Xuemei Wang, Hui Li · 2026 · Mechanisms of Ageing and Development
  96. Meta-analysis of DNA methylation aging signatures in 17 human tissues
    Macsue Jacques, Kirsten Seale, Sarah Amandine Caroline Voisin, Anna Lysenko, Robin Grolaux, Bernadette Jones-Freeman, Séverine Lamon, Mandhri Abeysooriya, Itamar Levinger, Carlie Bauer et al. · 2026 · Nature Aging
  97. Dietary supplementation with nicotinamide riboside improves fetal growth under hypoglycemia
    Sang R. Lee, Su Hee Jeong, Moeka Mukae, Sang-Yun Kim, Je‐Won Ko, Hyo‐Jung Kwun, Eui‐Ju Hong · 2023 · The Journal of Nutritional Biochemistry
  98. Nicotinamide phosphoribosyl transferase in mammary gland epithelial cells is required for nicotinamide mononucleotide production in mouse milk
    Kouya Hattori, Kanako Kobayashi, Rika Azuma-Suzuki, Kazuko Iwasa, Seiichiro Higashi, Takashige Hamaguchi, Yoshie Saito, Masashi Morifuji, Yo-ichi Nabeshima · 2024 · Biochemical and Biophysical Research Communications
  99. FAHD1 and mitochondrial metabolism: a decade of pioneering discoveries
    Elia Cappuccio, Max Holzknecht, Michèle Petit, Anne Heberle, Yana Rytchenko, Athanasios Seretis, Ciro Leonardo Pierri, Hubert Gstach, Pidder Jansen‐Dürr, Alexander K. H. Weiss · 2024 · FEBS Journal
  100. UPRmt alleviates bone cancer pain through the restoration of mitochondrial function
    Dan Li, Mingming Xie, Haohao Zeng, Jiacheng Yu, Rui Xu, Zhen Wang, Yulin Huang, Yan Yang, Yue Sun · 2025 · Experimental Cell Research