NAD + repletion improves mitochondrial and stem cell function and enhances life span in mice
Zhang, Hongbo, Ryu, Dongryeol, Wu, Yibo, Gariani, Karim, Wang, Xu, Luan, Peiling, D’Amico, Davide, Ropelle, Eduardo R. +5 more·2016·Science
Cited by (1,000)
Items 401–500 of 1,000
- Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic TherapiesLiyao Zheng, Shipei He, Hong Wang, Jinling Li, Yuanyuan Liu, Sijia Liu · 2024 · Aging and Disease
- Mitochondrial glycerol 3‐phosphate dehydrogenase promotes skeletal muscle regenerationXiufei Liu, Hua Qu, Yi Zheng, Qian Liao, Linlin Zhang, Xiaoyu Liao, Xin Xiong, Yuren Wang, Rui Zhang, Hui Wang et al. · 2018 · EMBO Molecular Medicine
- Implications of NAD+ Metabolism in the Aging Retina and Retinal DegenerationRavirajsinh Navalsinh Jadeja, Menaka Chanu Thounaojam, Manuela Bartoli, Pamela Moore Martin · 2020 · Oxidative Medicine and Cellular Longevity
- Restoring aged stem cell functionality: Current progress and future directionsKevin Spehar, Andrew Pan, Isabel Beerman · 2020 · Stem Cells
- Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKIPetra Šimić, Xavier Fernando Vela Parada, Samir M. Parikh, Ryan W. Dellinger, Leonard Guarente, Eugene P. Rhee · 2020 · BMC Nephrology
- Nicotinamide riboside and nicotinamide mononucleotide facilitate NAD
<sup>+</sup>
synthesis via enterohepatic circulationYaku, Keisuke, Palikhe, Sailesh, Iqbal, Tooba, Hayat, Faisal, Watanabe, Yoshiyuki, Fujisaka, Shiho, Izumi, Hironori, Yoshida, Tomoyuki, Karim, Mariam, Uchida, Hitoshi et al. · 2025 · Science Advances
- Early Life Stress and Metabolic Plasticity of Brain Cells: Impact on Neurogenesis and AngiogenesisAlla B. Salmina, Yana V. Gorina, Yulia K. Komleva, Yu. A. Panina, Natalia A. Malinovskaya, Olga L. Lopatina · 2021 · Biomedicines
- Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidationLynn‐Jee Kim, Timothy J. Chalmers, Romanthi J. Madawala, Greg C. Smith, Catherine Li, Abhirup Das, Eric Wing Keung Poon, Jun Wang, Simon P. Tucker, David A. Sinclair et al. · 2023 · FEBS Letters
- Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trialKristoffer Larsen Norheim, Michael Ben Ezra, Indra Heckenbach, Louise Munkholm Andreasson, Lise Lotte Eriksen, Nanna Dyhre‐Petersen, Mads V. Damgaard, Magnus Berglind, Luca Pricolo, Dayle L. Sampson et al. · 2024 · Nature Aging
- Chemical and Physiological Features of Mitochondrial AcylationAlison Epstein Ringel, Sarah A. Tucker, Marcia C. Haigis · 2018 · Molecular Cell
- Balancing NAD+ deficits with nicotinamide riboside: therapeutic possibilities and limitationsAngelique Cercillieux, Eleonora Ciarlo, Carles Cantó · 2022 · Cellular and Molecular Life Sciences
- Mitochondria-Targeted Therapeutics for Alzheimer's Disease: The Good, the Bad, the PotentialMi, Yashi, Qi, Guoyuan, Brinton, Roberta Diaz, Yin, Fei · 2021 · Antioxidants & Redox Signaling
- NAD+ Metabolism, Metabolic Stress, and InfectionBenjamin Groth, Padmaja Venkatakrishnan, Su-Ju Lin · 2021 · Frontiers in Molecular Biosciences
- A systems-approach to NAD+ restorationNichola J. Conlon, Dianne Ford · 2022 · Biochemical Pharmacology
- PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic RhythmsYing He, Alana Taub, Lexiang Yu, Yifan Yao, Ruotong Zhang, Tarik Zahr, Nicole Aaron, Joseph LeSauter, Lihong Fan, Longhua Liu et al. · 2022 · Advanced Science
- Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense systemHeein Yoon, Seung Gwa Park, Hyun‐Jung Kim, Hye‐Rim Shin, Ki‐Tae Kim, Young‐Dan Cho, Jae-I Moon, Min Sang Park, Woo Jin Kim, Hyun‐Mo Ryoo · 2023 · Experimental & Molecular Medicine
- Nicotinamide Riboside, a Promising Vitamin B3 Derivative for Healthy Aging and Longevity: Current Research and PerspectivesAndrei Biţă, Ion Romulus Scorei, Maria Viorica Ciocîlteu, Oana Elena Nicolaescu, Andreea Silvia Pîrvu, Ludovic Everard Bejenaru, Gabriela Rău, Cornelia Bejenaru, Antonia Radu, Johny Neamţu et al. · 2023 · Molecules
- Sirt6 deletion in bone marrow-derived cells increases atherosclerosis – Central role of macrophage scavenger receptor 1Tasneem Arsiwala, Jürgen Pahla, Lambertus J. van Tits, Lavinia Bisceglie, Daniel S. Gaul, Sarah Costantino, Melroy X Miranda, Kathrin Nussbaum, Simona Stivala, Przemysław Błyszczuk et al. · 2020 · Journal of Molecular and Cellular Cardiology
- A potential therapeutic effect of catalpol in Duchenne muscular dystrophy revealed by binding with TAK1Dengqiu Xu, Lei Zhao, Jingwei Jiang, Sijia Li, Zeren Sun, Xiaofei Huang, Chunjie Li, Tao Wang, Lixin Sun, Xihua Li et al. · 2020 · Journal of Cachexia Sarcopenia and Muscle
- The Gene-Regulatory Footprint of Aging Highlights Conserved Central RegulatorsMaroun S. Bou Sleiman, Pooja Jha, Riekelt H. Houtkooper, Robert W. Williams, Xu Wang, Johan H. Auwerx · 2020 · Cell Reports
- Mono(ADP-ribosyl)ation Enzymes and NAD+ Metabolism: A Focus on Diseases and Therapeutic PerspectivesPalmiro Poltronieri, Angela Celetti, Luca Palazzo · 2021 · Cells
- Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD + and Suppresses Glycolysis, the TCA Cycle, and Cell GrowthYan Liu, Chengting Luo, Ting Li, Wenhao Zhang, Zhaoyun Zong, Xiaohui Liu, Haiteng Deng · 2021 · Journal of Proteome Research
- Maintenance of NAD+ Homeostasis in Skeletal Muscle during Aging and ExerciseLi Li Ji, Dongwook Yeo · 2022 · Cells
- A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individualsJensen, Jonas Brorson, Dollerup, Ole L., Møller, Andreas B., Billeskov, Tine B., Dalbram, Emilie, Chubanava, Sabina, Damgaard, Mads V., Dellinger, Ryan W., Trošt, Kajetan, Moritz, Thomas et al. · 2022 · JCI Insight
- Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrityJoanna A. Ruszkiewicz, Alexander Bürkle, Aswin Mangerich · 2022 · Journal of Biological Chemistry
- Epigenetic clocks provide clues to the mystery of uterine ageingPavel I. Deryabin, Aleksandra V. Borodkina · 2022 · Human Reproduction Update
- A Promising Strategy to Treat Neurodegenerative Diseases by SIRT3 ActivationAlpna Tyagi, Subbiah Pugazhenthi · 2023 · International Journal of Molecular Sciences
- Epigenetic Regulation of Aging and its RejuvenationYongpan An, Qian Wang, Ke Gao, Chi Zhang, Yanan Ouyang, Ruixiao Li, Ma Zhou, Tong Wu, Lifan Zhou, Zhengwei Xie et al. · 2025 · MedComm
- Ghrelin mediated neuroprotection - A possible therapy for Parkinson's disease?A. Morgan, Daniel Rees, Z. Andrews, J. Davies · 2017 · Neuropharmacology
- ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal TransitionWeixuan Wang, Yadong Hu, Xiaofei Wang, Qingtao Wang, Haiteng Deng · 2018 · Cell chemical biology
- Prohibitin is a positive modulator of mitochondrial function in PC 12 cells under oxidative stressCorey J. Anderson, Anja Kahl, Liping Qian, Анна Степанова, Anatoly A. Starkov, Giovanni Manfredi, Costantino Iadecola, Ping Zhou · 2018 · Journal of Neurochemistry
- The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolismRachel S. Fletcher, Gareth Geoffrey Lavery · 2018 · Journal of Molecular Endocrinology
- Pyruvate Protects against Cellular Senescence through the Control of Mitochondrial and Lysosomal Function in Dermal FibroblastsJeong Yeon Kim, Sung Hoon Lee, Il‐Hong Bae, Dong Wook Shin, Daejin Min, Mira Ham, KyuHan Kim, Tae Ryong Lee, Hyoung-June Kim, Eui Dong Son et al. · 2018 · Journal of Investigative Dermatology
- Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal TransitionWeixuan Wang, Yadong Hu, Changmei Yang, Songbiao Zhu, Xiaofei Wang, Zhenyu Zhang, Haiteng Deng · 2018 · Molecular & Cellular Proteomics
- Nicotinamide riboside supplementation dysregulates redox and energy metabolism in rats: Implications for exercise performanceI. A. Kourtzidis, Christina F. Dolopikou, A. N. Tsiftsis, Nikos V. Margaritelis, Anastasios A. Theodorou, Ioannis A Zervos, Maria P. Tsantarliotou, Aristidis S. Veskoukis, Ioannis S. Vrabas, Vassilis Paschalis et al. · 2018 · Experimental Physiology
- Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacityMorten Dall, Samuel A.J. Trammell, Magnus Asping, Anna S. Hassing, Marianne Agerholm, Sara G. Vienberg, Matthew Paul Gillum, Steen Larsen, Jonas T. Treebak · 2019 · Journal of Biological Chemistry
- Rapamycin maintains NAD+/NADH redox homeostasis in muscle cellsZhigang Zhang, He N. Xu, Siyu Li, Antonio Dávila, Karthikeyani Chellappa, James G. Davis, Yuxia Guan, David W. Frederick, Weiqing Chu, Huaqing Zhao et al. · 2020 · Aging
- Systemic Treatment with Nicotinamide Riboside Is Protective in Two Mouse Models of Retinal Ganglion Cell DamageXian Zhang, Nan Zhang, Micah A. Chrenek, Preston E. Girardot, Jiaxing Wang, Jana T Sellers, Eldon E. Geisert, Charles Brenner, John M. Nickerson, Jeffrey H. Boatright et al. · 2021 · Pharmaceutics
- Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney diseaseArmin Ahmadi, Gwénaëlle Begue, Ana P. Valencia, Jennifer Norman, Benjamin Lidgard, Brian J. Bennett, Matt Van Doren, David Joseph Marcinek, Sili Fan, David K. Prince et al. · 2023 · JCI Insight
- The Emerging Role of Senotherapy in Cancer: A Comprehensive ReviewSarubala Malayaperumal, Francesco Marotta, Makalakshmi Murali Kumar, Indumathi Somasundaram, Antonio Ayala, Mario Faustino Muñoz Pinto, Antara Banerjee, Surajit Pathak · 2023 · Clinics and Practice
- Mitophagy in Alzheimer's disease and other metabolic disorders: A focus on mitochondrial-targeted therapeuticsShadt Skawratananond, Daniel X. Xiong, Charlie Zhang, Sahil S. Tonk, Aljon Pinili, Brad Delacruz, Patrick Pham, Shane C. Smith, Rahul Navab, P. Hemachandra Reddy · 2025 · Ageing Research Reviews
- The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasomeJavier Traba, Michael N. Sack · 2016 · Cellular and Molecular Life Sciences
- Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD)Keisuke Yaku, Keisuke Okabe, Maryam Gulshan, Kiyoshi Takatsu, Hiroshi Okamoto, Takashi Nakagawa · 2019 · Scientific Reports
- Physiological Systems in Promoting FrailtyLaís R. Perazza, Holly M. Brown‐Borg, LaDora V. Thompson · 2022 · Comprehensive physiology
- Current Uncertainties and Future Challenges Regarding NAD+ Boosting StrategiesBorut Poljšak, Vito Kovač, Irina Milisav · 2022 · Antioxidants
- The central role of DNA damage in immunosenescenceLoren Kell, Anna Katharina Simon, Ghada Alsaleh, Lynne S. Cox · 2023 · Frontiers in Aging
- Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trialMary McGrae McDermott, Christopher R. Martens, Kathryn J. Domanchuk, Dongxue Zhang, Clara Bien Peek, Michael H. Criqui, Luigi Ferrucci, Philip Greenland, Jack M. Guralnik, Karen J. Ho et al. · 2024 · Nature Communications
- Roles of Diffusion Dynamics in Stem Cell Signaling and Three-Dimensional Tissue DevelopmentRichard J. McMurtrey · 2017 · Stem Cells and Development
- Estimation of the Mitochondrial Membrane Potential Using Fluorescence Lifetime Imaging MicroscopyIrina A. Okkelman, Dmitri B. Papkovsky, Ruslan I. Dmitriev · 2019 · Cytometry Part A
- Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathwayHyebeen Kim, Sung Chun Cho, Hyeon‐Ju Jeong, Hye‐Young Lee, Myong‐Ho Jeong, Jung‐Hoon Pyun, Dongryeol Ryu, Minseok Kim, Young‐Sam Lee, Minseok S. Kim et al. · 2020 · Journal of Cachexia Sarcopenia and Muscle
- A comparative study of metformin and nicotinamide riboside in alleviating tissue aging in ratsLingling Geng, Bin Zhang, Haisong Liu, Si Wang, Yusheng Cai, Kuan Yang, Zhiran Zou, Xiaoyu Jiang, Zunpeng Liu, Wei Li et al. · 2022 · Life Medicine
- Oxidative Status Predicts Quality in Human Mesenchymal Stem CellsBertolo, Alessandro, Capossela, Simona, Fränkl, Gion, Baur, Martin, Pötzel, Tobias, Stoyanov, Jivko · 2017 · Stem Cell Research & Therapy
- Inhibition of NAMPT decreases cell growth and enhances susceptibility to oxidative stressXu, Renhua, Yuan, Zhenwei, Yang, Lijuan, Li, Lele, Li, Dan, Lv, Changjun · 2017 · Oncology Reports
- Pyridine Dinucleotides from Molecules to ManJoshua P. Fessel, William M. Oldham · 2017 · Antioxidants and Redox Signaling
- CD38 is methylated in prostate cancer and regulates extracellular NAD+Jack Mottahedeh, Michael C. Haffner, Tristan Grogan, Takao Hashimoto, Preston D. Crowell, Himisha Beltran, Andrea Sboner, Rohan Bareja, David Esopi, William B. Isaacs et al. · 2018 · Cancer & Metabolism
- Extracellular signal-regulated kinase 1/2 regulates NAD metabolism during acute kidney injury through microRNA-34a-mediated NAMPT expressionJustin B. Collier, Rick G. Schnellmann · 2019 · Cellular and Molecular Life Sciences
- Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancerTanaya Lahiri, Lara Brambilla, Joshua Andrade, Manor Askenazi, Beatrix M. Ueberheide, David E. Levy · 2021 · Molecular Oncology
- Bifidobacterium adolescentis-derived nicotinic acid improves host skeletal muscle mitochondrial function to ameliorate sarcopeniaZeng Zhang, Quan Guo, Zhihan Yang, Yukai Sun, Shuaiming Jiang, Yangli He, Jiahe Li, Jiachao Zhang · 2025 · Cell Reports
- Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical TrialPremranjan Kumar, Chun Liu, James W. Suliburk, Charles Gene Minard, Raja Muthupillai, Shaji K. Chacko, Jean W.-C. Hsu, Farook Jahoor, Rajagopal V. Sekhar · 2020 · Biomedicines
- Intimate Relations—Mitochondria and AgeingMichael Webb, Dionisia P. Sideris · 2020 · International Journal of Molecular Sciences
- The efficacy of cholesterol-lowering action and side effects of garlic enteric coated tablets in man.Jaivan Tanamai, Sornchai Veeramanomai, Nisa Indrakosas · 2004 · PubMed
- Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammationElizabeth A. Novak, Erin C. Crawford, Heather L. Mentrup, Brian D. Griffith, David M. Fletcher, Meredith R. Flanagan, Corinne Schneider, Brian Firek, Matthew Brian Rogers, Michael J. Morowitz et al. · 2023 · Frontiers in Immunology
- Metabolic Signaling into Chromatin Modifications in the Regulation of Gene ExpressionTian Xiang Gao, Zyanya Díaz-Hirashi, Francisco Verdeguer · 2018 · International Journal of Molecular Sciences
- NAD+ precursor increases aerobic performance in miceBárbara Crisol, Camilla Bertuzzo Veiga, Renata Rosseto Braga, Luciene Lenhare, Igor L. Baptista, Rafael Calais Gaspar, Vítor Rosetto Muñoz, André V. Cordeiro, Adelino Sánchez Ramos da Silva, Dennys E. Cintra et al. · 2019 · European Journal of Nutrition
- The NADase enzyme CD38: an emerging pharmacological target for systemic sclerosis, systemic lupus erythematosus and rheumatoid arthritisThais Peclat, Bo Shi, John Varga, Eduardo N. Chini · 2020 · Current Opinion in Rheumatology
- Exogenous NAD+ Postpones the D-Gal-Induced Senescence of Bone Marrow-Derived Mesenchymal Stem Cells via Sirt1 SignalingJie Wang, Lin Liu, Zhong Jie Ding, Qing Luo, Yang Ju, Guanbin Song · 2021 · Antioxidants
- The Slc25a47 locus is a novel determinant of hepatic mitochondrial function implicated in liver fibrosisNadia Bresciani, Hadrien Demagny, Vera Lemos, Francesca Pontanari, Xiaoxu Li, Yu Sun, Hao Li, Alessia Perino, Johan H. Auwerx, Kristina Schoonjans · 2022 · Journal of Hepatology
- Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial FactorsKatarzyna A. Cieslik, Rajagopal V. Sekhar, Alejandro Granillo, Anilkumar K. Reddy, Guillermo Medrano, Celia Pena Heredia, Mark L. Entman, Dale J. Hamilton, Shumin Li, Erin L. Reineke et al. · 2018 · The Journals of Gerontology Series A
- Psat1-generated α-ketoglutarate and glutamine promote muscle stem cell activation and regenerationVeronica Ciuffoli, Xuesong Feng, Kan Jiang, Natalia Acevedo-Luna, Kyung Dae Ko, A. Hong Jun Wang, Giulia Riparini, Mamduh Khateb, Brian C. Glancy, Stefania Dell’Orso et al. · 2024 · Genes & Development
- NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in Physically Compromised Older AdultsConnell, NJ, Grevendonk, L, Fealy, CE, Moonen-Kornips, E, Bruls, YMH, Schrauwen-Hinderling, VB, de Vogel, J, Hageman, R, Geurts, J, Zapata-Perez, R et al. · 2021 · The Journal of Nutrition
- Context‐dependent roles of cellular senescence in normal, aged, and disease statesMoiseeva, Victoria, Cisneros, Andrés, Cobos, Aina Calls, Tarrega, Aida Beà, Oñate, Claudia Santos, Perdiguero, Eusebio, Serrano, Antonio L., Muñoz‐Cánoves, Pura · 2023 · The FEBS Journal
- Metabolic regulation of the neural stem cell fate: Unraveling new connections, establishing new conceptsIoannis Angelopoulos, Georgios Gakis, Kyriakos Birmpas, Christina Kyrousi, Evagelia E Habeos, Konstantina Kaplani, Zoi Lygerou, Ioannis G. Habeos, Stavros L. Taraviras · 2022 · Frontiers in Neuroscience
- Targeting NAD Metabolism for the Therapy of Age-Related Neurodegenerative DiseasesFeifei Li, Chou Wu, Gelin Wang · 2023 · Neuroscience Bulletin
- Cellular senescence in chronic obstructive pulmonary disease: Molecular mechanisms and therapeutic interventionsSapana Subedi, Mounika Guntipally, Newton Suwal, Rajan Thapa, Saroj Bashyal, Nisha Panth, Gaurav Gupta, Ronan J. MacLoughlin, Brian Gregory George Oliver, Kamal Dua et al. · 2025 · Ageing Research Reviews
- Immunotherapy and senolytics in head and neck squamous cell carcinoma: phase 2 trial resultsNiu Liu, Jiaying Wu, Enze Deng, Jianglong Zhong, Bin Wei, Tingting Cai, Zhijun Xie, Xiaohui Duan, Sha Fu, David O. Osei-Hwedieh et al. · 2025 · Nature Medicine
- Rejuvenating stem cells to restore muscle regeneration in agingEyal Bengal, Eusebio Perdiguero, Antonio L. Serrano, Pura Muñoz‐Cánoves · 2017 · F1000Research
- Genetic cartography of longevity in humans and mice: Current landscape and horizonsMichael Hook, Suheeta Roy, Evan G. Williams, Maroun S. Bou Sleiman, Khyobeni Mozhui, James F. Nelson, Lu Lu, Johan H. Auwerx, Robert W. Williams · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Transcriptome analysis reveals a molecular understanding of nicotinamide and butyrate sodium on meat quality of broilers under high stocking densityYuqin Wu, Youli Wang, Dafei Yin, Tahir Mahmood, Jianmin Yuan · 2020 · BMC Genomics
- Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver diseaseJean-Christophe Simard, Jean-François Thibodeau, Martin Leduc, Mikaël Tremblay, Alexandre Laverdure, François Sarra‐Bournet, William Gagnon, Jugurtha Ouboudinar, Liette Gervais, Alexandra Felton et al. · 2020 · Scientific Reports
- Construction of an Alternative NAD + De Novo Biosynthesis PathwayYong Ding, Xinli Li, Geoff P. Horsman, Pengwei Li, Min Wang, Jine Li, Zhilong Zhang, Weifeng Liu, Bian Wu, Yong Tao et al. · 2021 · Advanced Science
- Adipogenic progenitors in different organs: Pathophysiological implicationsFrancesca Favaretto, S. Bettini, Luca Busetto, Gabriella Milan, Roberto Vettor · 2021 · Reviews in Endocrine and Metabolic Disorders
- Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc DegenerationWenning Xu, Chun Liu, Huo‐Liang Zheng, Haixia Xu, Runze Yang, Sheng‐Dan Jiang, Li-xin Zhu · 2023 · International Journal of Biological Sciences
- A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinomaKuan‐Ting Lin, Wai Kit Ma, Juergen Scharner, Yun‐Ru Liu, Adrian R. Krainer · 2018 · Genome Research
- Rejuvenation of Mesenchymal Stem Cells to Ameliorate Skeletal AgingMingjia Cheng, Weihao Yuan, Alireza Moshaverinia, Bo Yu · 2023 · Cells
- Molecular hallmarks of ageing in amyotrophic lateral sclerosisCyril Jones Jagaraj, Sina Shadfar, Sara Assar Kashani, Sayanthooran Saravanabavan, Fabiha Farzana, Julie D. Atkin · 2024 · Cellular and Molecular Life Sciences
- Enhancing healthy aging with small molecules: A mitochondrial perspectiveXiujiao Qin, Hongyuan Li, Huiying Zhao, Le Fang, Xiaohui Wang · 2024 · Medicinal Research Reviews
- Therapeutic potential of systemic brain rejuvenation strategies for neurodegenerative diseaseAlana M. Horowitz, Saul Villeda · 2017 · F1000Research
- Aging and stem cell therapyMohammadhossein Khorraminejad‐Shirazi, Mohammad Farahmandnia, Bahareh Kardeh, AliReza Estedlal, Sina Kardeh, Ahmad Monabati · 2017 · Hematology/Oncology and Stem Cell Therapy
- Sirtuins and Accelerated Aging in SclerodermaAnne E. Wyman, Sergei P. Atamas · 2018 · Current Rheumatology Reports
- Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communicationKnut Husø Lauritzen, Maria Belland Olsen, Mohammed Shakil Ahmed, Kuan Yang, Johanne Egge Rinholm, Linda Hildegard Bergersen, Qin Ying Esbensen, Lars Jansen Sverkeli, Mathias Ziegler, Håvard Attramadal et al. · 2021 · eLife
- Metabolomic Profiling of Poor Ovarian Response Identifies Potential Predictive BiomarkersHaixia Song, Qin Qin, Caixia Yuan, Hong Li, Fang Zhang, Lingling Fan · 2021 · Frontiers in Endocrinology
- Therapeutic Potential of Emerging NAD+-Increasing Strategies for Cardiovascular DiseasesNoemí Rotllán, Mercedes Camacho, Mireia Tondo, Elena M. G. Diarte‐Añazco, Marina Canyelles, Karen Alejandra Méndez‐Lara, Sònia Benı́tez, Núria Alonso, Dı́dac Mauricio, Joan Carles Escolá‐Gil et al. · 2021 · Antioxidants
- Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathyNicole M. Sayles, Nneka Southwell, Kevin J. McAvoy, Kihwan Kim, Alba Pesini, Corey J. Anderson, Catarina Maria Quinzii, Suzanne M. Cloonan, Hibiki Kawamata, Giovanni Manfredi · 2022 · Cell Reports
- Nicotinamide riboside intervention alleviates hematopoietic system injury of ionizing radiation‐induced premature aging miceWenxuan Li, Xinyue Wang, Yinping Dong, Qidong Huo, Tongpeng Yue, Xinyu Wu, Lu Lu, Junling Zhang, Yu Zhao, Hui Dong et al. · 2023 · Aging Cell
- Mitochondria pleiotropism in stem cell senescence: Mechanisms and therapeutic approachesCristina Mas‐Bargues · 2023 · Free Radical Biology and Medicine
- DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiationLucia Latella, Alessandra Dall’Agnese, Francesca Boscolo Sesillo, Chiara Nardoni, Marianna Cosentino, Armin Lahm, Alessandra Sacco, Prem Puri · 2017 · Genes & Development
- NAD + Precursors in Human Health and Disease: Current Status and Future ProspectsKeisuke Yaku, Takashi Nakagawa · 2023 · Antioxidants and Redox Signaling
- Nicotinamide riboside induces a thermogenic response in lean miceBárbara Crisol, Camilla Bertuzzo Veiga, Luciene Lenhare, Renata Rosseto Braga, Vagner Ramon Rodrigues Silva, Adelino Sánchez Ramos da Silva, Dennys E. Cintra, Leandro Pereira de Moura, José Rodrigo Pauli, Eduardo Rochete Ropelle · 2018 · Life Sciences
- Apoptosis inducing factor deficiency causes retinal photoreceptor degeneration. The protective role of the redox compound methylene blueNaveen Kumar Mekala, Jacob Kurdys, Mikayla M. Depuydt, Edwin J. Vazquez, Mariana Georgeta Rosca · 2018 · Redox Biology
- Improved mitochondrial stress response in long‐lived Snell dwarf miceUlas Ozkurede, Richard A. Miller · 2019 · Aging Cell