Mutational signatures associated with tobacco smoking in human cancer

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Items 501–600 of 1,000

1. Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers
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2. Characteristics of genomic mutations and signaling pathway alterations in thymic epithelial tumors
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3. DNA adduct formation and reduced EIF4A3expression contributes to benzo[a]pyrene-induced DNA damage in human bronchial epithelial BEAS-2B cells
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4. Smoking-associated Downregulation of FILIP1L Enhances Lung Adenocarcinoma Progression Through Mucin Production, Inflammation, and Fibrosis
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6. Novel targeted strategies to overcome resistance in small-cell lung cancer: focus on PARP inhibitors and rovalpituzumab tesirine
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7. Subtyping of head and neck squamous cell cancers based on immune signatures
   Dandan Song, Haoyu Lyu, Qiushi Feng, Jiangti Luo, Lin Li, Xiaosheng Wang · 2021 · International Immunopharmacology
8. Genetics and Molecular Biology of Head and Neck Cancer
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9. Exploratory genomic analysis of high-grade neuroendocrine neoplasms across diverse primary sites
   Thomas Yang Sun, Lan Zhao, Paul Van Hummelen, Brock A. Martin, Kathleen Hornbacker, HoJoon Lee, Li C Xia, Sukhmani Kaur Padda, Hanlee P. Ji, Pamela L. Kunz · 2022 · Endocrine Related Cancer
10. Artificial Intelligence (AI) and Ethics in Medicine at a Global Level: Benefits and Risks
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11. Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans
    Kathleen M. Hudson, Leszek J. Klimczak, Joan F. Sterling, Adam Burkholder, Marat D. Kazanov, Natalie Saini, Piotr A. Mieczkowski, Dmitry A. Gordenin · 2023 · Nucleic Acids Research
12. Precision medicine for pancreatic cancer: characterizing the clinicogenomic landscape and outcomes of KRAS G12C-mutated disease
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13. Deciphering the dynamic code: DNA recognition by transcription factors in the ever-changing genome
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14. Integrated genomic/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin
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15. NGS-based analysis of base-substitution signatures created by yeast DNA polymerase eta and zeta on undamaged and abasic DNA templates in vitro
    Yizhang Chen, Tomohiko Sugiyama · 2017 · DNA repair
16. Making headlines: an analysis of US government-funded cancer research mentioned in online media
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17. Defining relative mutational difficulty to understand cancer formation
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18. Smoking status-based efficacy difference in anti-PD-1/PD-L1 immunotherapy: a systematic review and meta-analysis
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19. Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity
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20. A phylogenetic approach to study the evolution of somatic mutational processes in cancer
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21. CHRNA5 and CHRNA3 polymorphism and lung cancer susceptibility in Palestinian population
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22. Short-term regulation of the hepatic activities of cytochrome P450 and glutathione S-transferase by nose-only cigarette smoke exposure in mice
    Chang Seon Ryu, Young Jae Choi, Hyo Seon Nam, Jang Su Jeon, Taeyoon Jung, Ji‐Eun Park, Seong‐Jin Choi, Kyuhong Lee, Moo‐Yeol Lee, Sang Kyum Kim · 2019 · Food and Chemical Toxicology
23. Prenatal exposure to particulate matter and ozone: Bulky DNA adducts, plasma isoprostanes, allele risk variants, and neonate susceptibility in the Mexico City Metropolitan Area
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24. Interaction of tobacco chewing and smoking habit with interleukin 6 promoter polymorphism in oral precancerous lesions and oral cancer
    Yadvendra Shahi, Sayali Mukherjee, Fahad Mansoor Samadi · 2021 · European Archives of Oto-Rhino-Laryngology
25. Woody leguminous trees: New uses for sustainable development of drylands
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26. Smoking history influences the prognostic value of peripheral naïve CD4+ T cells in advanced non-small cell lung cancer
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27. Initial whole-genome sequencing of plasma cell neoplasms in first responders and recovery workers exposed to the World Trade Center attack of September 11, 2001
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28. Oxidative Stress and the Intersection of Oncogenic Signaling and Metabolism in Squamous Cell Carcinomas
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29. In Utero and Childhood/Adolescence Exposure to Tobacco Smoke, Genetic Risk, and Cancer Incidence in Adulthood: A Prospective Cohort Study
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30. Predicting functional UTR variants by integrating region-specific features
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31. Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution
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32. APOBEC affects tumor evolution and age at onset of lung cancer in smokers
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33. Smoke signals in the DNA of normal lung cells
    Gerd P. Pfeifer · 2020 · Nature
34. A New TTZ Feature Extracting Algorithm to Decipher Tobacco Related Mutation Signature Genes for the Personalized Lung Adenocarcinoma Treatment
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35. The benefits of smoking cessation on survival in cancer patients by integrative analysis of multi‐omics data
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36. Distinct Patterns of Somatic Genomic Alterations and Mutational Signatures in Central and Peripheral-Type Small-Cell Lung Cancer
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37. Exposure to Tobacco Smoking Induces a subset of Activated Tumor-resident Tregs in Non-Small Cell Lung Cancer
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38. Lung Cancer in Non-Smokers: Clinicopathological and Survival Differences from Smokers
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39. Inherited pulmonary cylindromas: extending the phenotype of CYLD mutation carriers
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40. The development of new pigments: Colorful g-C3N4-based catalysts for nicotine removal
    Shujun Chen, Wangyang Lü, Haibin Shen, Shasha Xu, Xia Chen, Tiefeng Xu, Yu Wang, Yi Chen, Yan Gu, Chun Wang et al. · 2019 · Applied Catalysis B: Environmental
41. CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations
    Andrew M. Leader, John A. Grout, Christie Chang, Barbara B. Maier, Alexandra Tabachnikova, Laura A. Walker, Alona Lansky, Jessica Le Bérichel, Naussica Malissen, Melanie Davila et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
42. Multi-omic stratification of the missense variant cysteinome
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43. ICI-based therapies: A new strategy for oral potentially malignant disorders
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44. Molecular classification of small cell lung cancer subtypes: Characteristics, prognostic factors, and clinical translation
    Hanfei Guo, Wenqian Li, Ye Guo, Naifei Chen, Jiuwei Cui · 2023 · Chinese Medical Journal
45. Deconstructing cancer with precision genome editing
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46. The impact of nicotine smoking on spondyloarthritis and rheumatoid arthritis
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47. Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNK
    Michael Korenjak, Nuri A. Temiz, Stéphane Keïta, Bérénice Chavanel, Claire Renard, Cécilia Sirand, Vincent Cahais, Tanguy Mayel, Karin R. Vevang, Foster C. Jacobs et al. · 2026 · Genome Medicine
48. Comprehensive genomic and spatial immune infiltration analysis of survival outliers in extensive-stage small cell lung cancer receiving first-line chemoimmunotherapy
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49. Cigarette Smoke-Induced Epithelial-to-Mesenchymal Transition: Insights into Cellular Mechanisms and Signaling Pathways
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50. Oncogenic RAS in Cancers from the DNA Replication Stress and Senescence Perspective
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51. TrackSigFreq: subclonal reconstructions based on mutation signatures and allele frequencies
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52. The Association of Modifiable Breast Cancer Risk Factors and Somatic Genomic Alterations in Breast Tumors: The Cancer Genome Atlas Network
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53. Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N–OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts
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54. 3D in vitro co-culture disc for spatiotemporal image analysis of cancer–stromal cell interaction
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55. Carcinogen-induced DNA structural distortion differences in the RAS gene isoforms; the importance of local sequence
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56. Investigation of somatic mutation profiles and tumor evolution of primary oropharyngeal cancer and sequential lymph node metastases using multiregional whole‐exome sequencing
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57. Gender differences in smoking-induced changes in the tumor immune microenvironment
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58. Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma
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59. Multiomic analysis of oral keratinocytes chronically exposed to shisha
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60. Do the Number of Cigarettes Smokes per day Contribute to the Incident of Malignant Cancer?
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61. The mutREAD method detects mutational signatures from low quantities of cancer DNA
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62. Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma
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63. Smoking habit and chemo-radiotherapy and/or surgery affect the sensitivity of EGFR plasma test in non-small cell lung cancer
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66. Quantifying smoking exposure, genomic correlates, and related risk of treatment failure in p16 + squamous cell carcinoma of the oropharynx
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67. Genetic mutations in smoking‐associated prostate cancer
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68. RB1 Mutations Induce Smoking‐Related Bladder Cancer by Modulating the Cytochrome P450 Pathway
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70. The epigenetic landscape shapes smoking-induced mutagenesis by modulating DNA damage susceptibility and repair efficiency
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71. Smoking and XPC Gene Polymorphism Interact to Modulate the Risk of Oral Cancer
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73. HNF1A POU Domain Mutations Found in Japanese Liver Cancer Patients Cause Downregulation of HNF4A Promoter Activity with Possible Disruption in Transcription Networks
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80. Molecular profiling identifies distinct subtypes across TP53 mutant tumors
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82. Sodium Valproate Inhibits Small Cell Lung Cancer Tumor Growth on the Chicken Embryo Chorioallantoic Membrane and Reduces the p53 and EZH2 Expression
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86. Mutation signatures to Pan-Cancer Atlas: Investigation of the genomic landscape of muscle-invasive bladder cancer
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87. New Breeding Techniques: Detection and Identification of the Techniques and Derived Products
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88. Clinicopathologic characteristics and outcomes for patients with KRAS G12D-mutant NSCLC
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89. Mutational landscape induced by chronic exposure to environmental PM10 and PM2.5 in A549 lung epithelial cell
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90. From COPD to Smoke-Related Arteriopathy: The Mechanical and Immune–Inflammatory Landscape Underlying Lung Cancer Distant Spreading—A Narrative Review
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91. Mutation of CMTR2 in Lung Adenocarcinoma Alters RNA Alternative Splicing and Reveals Therapeutic Vulnerabilities
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92. Genomic Analysis of Waterpipe Smoke-Induced Lung Tumor Autophagy and Plasticity
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93. Evaluating cancer etiology and risk with a mathematical model of tumor evolution
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94. Influence network model uncovers relations between biological processes and mutational signatures
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95. Computational Methods Summarizing Mutational Patterns in Cancer: Promise and Limitations for Clinical Applications
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96. TM4SF19 controls GABP-dependent YAP transcription in head and neck cancer under oxidative stress conditions
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97. Oncogene-Driven Non–Small Cell Lung Cancers in Patients with a History of Smoking Lack Smoking-Induced Mutations
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98. Mutational signature analyses in multi-child families reveal sources of age-related increases in human germline mutations
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99. Checkpoint based immunotherapy in non-small cell lung cancer: a real-world retrospective study
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100. Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma
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