The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
An intrinsic S/G 2 checkpoint enforced by ATR
Open accessAbstract
An additional cell cycle checkpoint: Cell division is controlled by checkpoints that regulate the temporal order of the cell cycle phases, including the G 1 /S, G 2 /M, and metaphase/anaphase transitions. Yet there are no known control mechanisms for a fourth fundamental transition—the S/G 2 transition. Saldivar et al. report a switchlike control mechanism that regulates the S/G 2 transition. The checkpoint kinase ATR senses ongoing DNA replication in S phase and represses the mitotic transcriptional network, ensuring that DNA replication in S phase is completed before mitosis. Science , this issue p. 806
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BEDTools: a flexible suite of utilities for comparing genomic features
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ATR disruption leads to chromosomal fragmentation and early embryonic lethality
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ATR prohibits replication catastrophe by preventing global exhaustion of RPA
Toledo, L. I., Altmeyer, M., Rask, M.-B., Lukas, C., Larsen, D. H., Povlsen, L. K., Bekker-Jensen, S., Mailand, N., Bartek, J., & Lukas, J. (2013) · Cell · doi:10.1016/j.cell.2013.10.043 · Cited by 911
The essential kinase ATR: ensuring faithful duplication of a challenging genome
Saldivar, J. C., Cortez, D., & Cimprich, K. A. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.67 · Cited by 838
Self-citationFoxM1 is required for execution of the mitotic programme and chromosome stability
Laoukili, J., Kooistra, M. R. H., Brás, A., Kauw, J., Kerkhoven, R. M., Morrison, A., Clevers, H., & Medema, R. H. (2005) · Nature Cell Biology · doi:10.1038/ncb1217 · Cited by 807
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Duy, C., Li, M., Teater, M., Meydan, C., Garrett-Bakelman, F. E., Lee, T. C., Chin, C. R., Durmaz, C., Kawabata, K. C., Dhimolea, E., et al. (2021) · Cancer Discovery · doi:10.1158/2159-8290.cd-20-1375 · Cited by 253
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Metadata
- Authors
- Saldivar, J. C., Hamperl, S., Bocek, M. J., Chung, M., Bass, T. E., Cisneros-Soberanis, F., Samejima, K., Xie, L., Paulson, J. R., Earnshaw, W. C., Cortez, D., Meyer, T., & Cimprich, K. A.
- Venue
- Science
- Published
- 2018-08-24
- Volume
- 361
- Issue
- 6404
- Pages
- 806-810
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2888068269
- Cited by
- 308
- References
- 37
- FWCI
- 10.12
- Type
- journal article
- Language
- en
- Open access
- green
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- Saldivar, J. C., Hamperl, S., Bocek, M. J., Chung, M., Bass, T. E., Cisneros-Soberanis, F., Samejima, K., Xie, L., Paulson, J. R., Earnshaw, W. C., Cortez, D., Meyer, T., & Cimprich, K. A. (2018). An intrinsic S/G 2 checkpoint enforced by ATR. Science. https://doi.org/10.1126/science.aap9346
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