The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.
Effects of microbiota-directed foods in gnotobiotic animals and undernourished children
Open accessAbstract
To examine the contributions of impaired gut microbial community development to childhood undernutrition, we combined metabolomic and proteomic analyses of plasma samples with metagenomic analyses of fecal samples to characterize the biological state of Bangladeshi children with severe acute malnutrition (SAM) as they transitioned, after standard treatment, to moderate acute malnutrition (MAM) with persistent microbiota immaturity. Host and microbial effects of microbiota-directed complementary food (MDCF) prototypes targeting weaning-phase bacterial taxa underrepresented in SAM and MAM microbiota were characterized in gnotobiotic mice and gnotobiotic piglets colonized with age- and growth-discriminatory bacteria. A randomized, double-blind controlled feeding study identified a lead MDCF that changes the abundances of targeted bacteria and increases plasma biomarkers and mediators of growth, bone formation, neurodevelopment, and immune function in children with MAM.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Supplementing children with moderate acute malnutrition with a microbiota-directed complementary food prototype shifted the microbiota as well as markers of neurodevelopment toward that of healthy children, indicating that the immature microbiota is causally linked to unhealthy growth and development, but can be rescued by microbiota-targeted food therapy (282).”
From Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health (2021) · cites this paper as [282]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Love, M. I., Huber, W., & Anders, S. (2014) · Genome Biology · doi:10.1186/s13059-014-0550-8 · Cited by 95,106
limma powers differential expression analyses for RNA-sequencing and microarray studies
Ritchie, M. E., Phipson, B., Wu, D., Hu, Y., Law, C. W., Shi, W., & Smyth, G. K. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv007 · Cited by 40,458
KEGG: Kyoto Encyclopedia of Genes and Genomes
Kanehisa, M. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.1.27 · Cited by 37,077
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
Yu, G., Wang, L.-G., Han, Y., & He, Q.-Y. (2012) · OMICS: A Journal of Integrative Biology · doi:10.1089/omi.2011.0118 · Cited by 36,259
QIIME allows analysis of high-throughput community sequencing data
Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887
Self-citationCutadapt removes adapter sequences from high-throughput sequencing reads
Martin, M. (2011) · EMBnet.journal · doi:10.14806/ej.17.1.200 · Cited by 33,889
KEGG: Kyoto Encyclopedia of Genes and Genomes
Ogata, H., Goto, S., Sato, K., Fujibuchi, W., Bono, H., & Kanehisa, M. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.1.29 · Cited by 31,232
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
Liao, Y., Smyth, G. K., & Shi, W. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btt656 · Cited by 27,219
SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing
Bankevich, A., Nurk, S., Antipov, D., Gurevich, A. A., Dvorkin, M. V., Kulikov, A. S., Lesin, V. M., Nikolenko, S., Pham, S., Prjibelski, A. D., et al. (2012) · Journal of Computational Biology · doi:10.1089/cmb.2012.0021 · Cited by 26,312
Search and clustering orders of magnitude faster than BLAST
Edgar, R. C. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq461 · Cited by 21,098
Flagged first, then by citations
Research works printed but not linked: 1
- MAL-ED Network Investigators, The Malnutrition and Enteric Disease Study (MAL-ED): Understanding the Consequences for Child Health and Development. Clin. Infect. Dis. 59, S193–S206 (2014).
Cited by
Sorted by citations
Items 201–300 of 433
Chai, L., Wang, H., Li, X., & Wang, H. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-23671-9 · Cited by 17
Persistent delay in maturation of the developing gut microbiota in infants with cystic fibrosis
Verster, A. J., Salerno, P., Valls, R. A., Barrack, K. E., Price, C. E., McClure, E. A., Madan, J. C., O’Toole, G. A., Sanville, J. L., & Ross, B. D. (2025) · mBio · doi:10.1128/mbio.03420-24 · Cited by 26
Orihara, K., Yahagi, K., Saito, Y., Watanabe, Y., Sasai, T., Hara, T., Tsukuda, N., Oki, K., Fujimoto, J., & Matsuki, T. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2207455 · Cited by 16
Davies, M. R., Greenberg, Z., van Vuurden, D. G., Cross, C., Zannettino, A. C. W., Bardy, C., & Wardill, H. R. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.10.013 · Cited by 17
Schwartz, D. J., Langdon, A. E., Sun, X., Langendorf, C., Berthé, F., Grais, R. F., Trehan, I., Isanaka, S., & Dantas, G. A. (2023) · The Lancet Microbe · doi:10.1016/s2666-5247(23)00213-6 · Cited by 16
Gut microbiota in regulation of childhood bone growth
Lui, J. C. K. (2023) · Experimental Physiology · doi:10.1113/ep091620 · Cited by 17
Qu, Z., Zhang, B., Lin, G., Guo, M., Tian, P., Wang, L., Chen, W., Zhang, H., & Wang, G. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.141333 · Cited by 16
Gut microbiota: a crucial player in the combat against tuberculosis
Jie, L., Chen, D., Yan, Y., Pi, J., Xu, J.-F., Chen, L., & Zheng, B. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1442095 · Cited by 16
Drosophila as a model system for deciphering the ‘host physiology–nutrition–microbiome’ axis
Lee, J.-H., Lee, K., & Lee, W. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2020.09.005 · Cited by 17
Microbial and nutritional influence on endocrine control of growth
Vadder, F. D., Joly, A., & Leulier, F. (2021) · Journal of Molecular Endocrinology · doi:10.1530/jme-20-0288 · Cited by 16
Immunological Impact of Intestinal T Cells on Metabolic Diseases
Zhou, H., Wang, L., & Liu, F. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.639902 · Cited by 19
Gut microbiota profiles of young South Indian children: Child sex-specific relations with growth
Shivakumar, N., Sivadas, A., Devi, S., Jahoor, F., McLaughlin, J. T., Smith, C. P., Kurpad, A. V., & Mukhopadhyay, A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0251803 · Cited by 18
Heuven, L. A. J., Pyle, S., Greyling, A., Melse‐Boonstra, A., & Eilander, A. (2021) · Current Developments in Nutrition · doi:10.1093/cdn/nzab124 · Cited by 20
Schneider, D. J., Lynch, S. A., Gelinas, A. D., Ostroff, R. M., Rohloff, J. C., Williams, P., Janjić, N., & Drolet, D. W. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821595-1.00007-5 · Cited by 14
Extracellular vesicle miRNAs as key mediators in diet-gut microbiome-host interplay
Dong, X., Liu, Y., Yang, X., & Li, T. (2023) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2023.05.005 · Cited by 16
Malnutrition, poor post-natal growth, intestinal dysbiosis and the developing lung
Underwood, M. A., Lakshminrusimha, S., Steinhorn, R. H., & Wedgwood, S. (2020) · Journal of Perinatology · doi:10.1038/s41372-020-00858-x · Cited by 16
Gut microbiome dysbiosis in malnutrition
Chawla, M., Gupta, R., & Das, B. (2022) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2022.07.011 · Cited by 16
Vlasova, A. N., Rajashekara, G., & Saif, L. J. (2018) · Drug Discovery Today Disease Models · doi:10.1016/j.ddmod.2019.08.006 · Cited by 15
Gut microbiota and bronchopulmonary dysplasia
Yang, K., He, S., & Dong, W. (2021) · Pediatric Pulmonology · doi:10.1002/ppul.25508 · Cited by 14
Understanding of the efficacy of gut microbiota-directed foods on human health
Fang, Q., Yu, L., Tian, F., Chen, W., & Zhai, Q. (2023) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2023.04.005 · Cited by 15
Gao, X., Xu, F., Li, T., Huang, P., Yu, L., Tian, F., Zhao, J., Chen, W., & Zhai, Q. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.128694 · Cited by 13
Malique, A., Sun, S., Chandwe, K., Amadi, B., Haritunians, T., Jain, U., Muegge, B. D., Frein, J., Sasaki, Y., Foster, A., et al. (2024) · Science Translational Medicine · doi:10.1126/scitranslmed.abq4145 · Cited by 15
Xu, Q., Wang, J., Zhang, Y., Li, Y., Qin, X., Xin, Y., Li, Y., Xu, K., Yang, X., & Wang, X. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c09511 · Cited by 14
Chehab, R. F., Cross, T.-W., & Forman, M. R. (2020) · Advances in Nutrition · doi:10.1093/advances/nmaa146 · Cited by 16
Weagley, J. S., Zaydman, M. A., Venkatesh, S., Sasaki, Y., Damaraju, N., Yenkin, A. L., Buchser, W., Rodionov, D. A., Osterman, A. L., Ahmed, T., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110738 · Cited by 13
Adaptive Responses in Severe Acute Malnutrition: Endocrinology, Metabolomics, Mortality, and Growth
PAGE, L. C., McCain, E., & Freemark, M. (2025) · Nutrients · doi:10.3390/nu17172864 · Cited by 15
Feeding Drosophila gut microbiomes from young and old flies modifies the microbiome
Wesseltoft, J. B., Danielsen, C. D., Andersen, A. M., de Jonge, N., Olsen, A., Rohde, P. D., & Kristensen, T. N. (2024) · Scientific Reports · doi:10.1038/s41598-024-58500-1 · Cited by 10
Matos, Y. A. S., Cano, J., Shafiq, H., Williams, C., Sunny, J., & Cowardin, C. A. (2024) · Microbiome · doi:10.1186/s40168-024-01783-3 · Cited by 12
Lalli, M., Salo, T. E., Hakola, L., Knip, M., Virtanen, S. M., & Vatanen, T. (2024) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2024.11.011 · Cited by 14
Complementary Feeding and Infant Gut Microbiota: A Narrative Review
Noles, D. L., Matzeller, K. L., Frank, D. N., Krebs, N. F., & Tang, M. (2025) · Nutrients · doi:10.3390/nu17050743 · Cited by 17
Lee, J. W., Lee, K.-A., Jang, I.-H., Nam, K.-B., Kim, S., Kyung, M., Cho, K.-C., Lee, J.-H., You, H., Kim, E. K., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57484-4 · Cited by 13
Millet-based supplement restored gut microbial diversity of acute malnourished pigs
Li, X., Yan, H., Leng, B., Ren, J., Song, Y., Che, L., Peng, X., Huang, B., Liu, S., Li, L., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250423 · Cited by 15
Metabolomic Comparison of Patients With Colorectal Cancer at Different Anticancer Treatment Stages
Li, Z., Deng, X., Luo, J., Lei, Y., Jin, X., Zhu, J., & Lv, G. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2021.574318 · Cited by 12
Microbial Normal Flora: Its Existence And Their Contribution To Homeostasis
Sunarti, L. S. (2022) · Journal of Advances in Microbiology · doi:10.9734/jamb/2022/v22i930483 · Cited by 13
Hendrixson, D. T., Naskidashvili, N., Stephenson, K. B., Laury, M. L., Koroma, A. S., & MANARY, M. J. (2022) · Journal of Nutrition · doi:10.1093/jn/nxac207 · Cited by 11
Iablokov, S. N., Novichkov, P. S., Osterman, A. L., & Rodionov, D. A. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.653314 · Cited by 11
Guild and Niche Determination Enable Targeted Alteration of the MicrobiomePreprint
Moyne, O., Al‐Bassam, M. M., Lieng, C., Thiruppathy, D., Norton, G. J., Kumar, M., Haddad, E., Zaramela, L. S., & Zengler, K. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.11.540389 · Cited by 12
Coley, E. J. L., Lum, G. R., Pronovost, G. N., Yu, L. W., Özcan, E., Yu, K. B., McDermott, J., Chakhoyan, A., Goldman, E., Vuong, H. E., et al. (2025) · Nature Microbiology · doi:10.1038/s41564-025-02022-7 · Cited by 13
Gut Microbes and Circulating Cytokines in Preterm Infants with Growth Failure
Strobel, K. M., Vecchio, G. D., Devaskar, S. U., & Calkins, K. L. (2022) · Journal of Nutrition · doi:10.1016/j.tjnut.2022.10.005 · Cited by 12
Schneider, E., Schmidt, R., Cryan, J. F., & Hilbert, A. (2024) · International Journal of Eating Disorders · doi:10.1002/eat.24326 · Cited by 11
Fischer, N., Darmstadt, G. L., Shahunja, K. M., Crowther, J. M., Kendall, L., Gibson, R. A., Ahmed, T., & Relman, D. A. (2021) · Journal of Global Health · doi:10.7189/jogh.11.04047 · Cited by 12
Zhang, Y., Zhang, Y., Chen, Z., Jia, Z., Yu, Y., Wang, J., & Liang, H. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1527765 · Cited by 10
Zhou, C., Hibberd, M. C., Lee, E. M., Pilgaard, B., Vuillemin, M., Kiehn, E., Henrissat, S., Crane, M., Cheng, J., Pfaff, L., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2521522122 · Cited by 9
Mostafa, I., Fahim, S. M., Das, S., Gazi, M. A., Hasan, M. M., Saqeeb, K. N., Mahfuz, M., Lynn, H. M., Barratt, M. J., Gordon, J. I., et al. (2022) · BMC Pediatrics · doi:10.1186/s12887-022-03436-6 · Cited by 10
Cancer and nutrition among children and adolescents in low- and middle-income countries
Barr, R. D., & Antillón‐Klussmann, F. (2022) · Hematology · doi:10.1080/16078454.2022.2115437 · Cited by 10
The regulatory effects of specific polyphenols on Akkermansia are dependent on uridine
Gao, X., Yue, C., Tian, R., Yu, L., Tian, F., Zhao, J., Chen, W., & Zhai, Q. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.135367 · Cited by 10
Melding microbiome and nutritional science with early child development
Chen, R. Y., Mostafa, I., Hibberd, M. C., Das, S., Lynn, H. M., Webber, D. M., Mahfuz, M., Barratt, M. J., Ahmed, T., & Gordon, J. I. (2021) · Nature Medicine · doi:10.1038/s41591-021-01451-1 · Cited by 10
Microbial Interventions to Improve Neonatal Gut Health
Nakandalage, R., Guan, L. L., & Malmuthuge, N. (2023) · Microorganisms · doi:10.3390/microorganisms11051328 · Cited by 10
Building better barriers: how nutrition and undernutrition impact pediatric intestinal health
Andres, S. F., Zhang, Y., Kuhn, M. R., & Scottoline, B. P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1192936 · Cited by 11
Controlled Complexity: Optimized Systems to Study the Role of the Gut Microbiome in Host Physiology
Glowacki, R. W. P., Engelhart, M. J., & Ahern, P. P. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.735562 · Cited by 10
Turning the “Phage” on Malnutrition and Stunting
Bolte, E., & Aagaard, K. M. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.01.020 · Cited by 9
Veeraraghavan, B., Dinh, D. M., Kane, A. V., Soofi, S. B., Ahmed, I., Rizvi, A., Chatterjee, M., Babji, S., Duara, J. L., Moy, J. X., et al. (2023) · Nutrients · doi:10.3390/nu15051213 · Cited by 8
Food-breastmilk combinations alter the colonic microbiome of weaning infants: an in silico study
da Silva, V. G., Smith, N. W., Mullaney, J. A., Wall, C. R., Roy, N. C., & McNabb, W. C. (2024) · mSystems · doi:10.1128/msystems.00577-24 · Cited by 9
Predicting competition and substrate preferences for targeted microbiome alteration
Moyne, O., Norton, G. J., Al‐Bassam, M. M., Lieng, C., Thiruppathy, D., Kumar, M., Haddad, E., Weng, Y., Raffatellu, M., Zaramela, L. S., et al. (2026) · Cell · doi:10.1016/j.cell.2026.03.036 · Cited by 10
van den Brink, D. A., de Meij, T. G. J., Brals, D., Bandsma, R., Thitiri, J., Ngari, M. M., Mwalekwa, L., de Boer, N. K. H., Wicaksono, A., Covington, J. A., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-75515-6 · Cited by 8
Bacterial Infections and Nutrition: A Primer
Berkley, J. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-56913-6_4 · Cited by 8
Rodriguez‐Sillke, Y., Visekruna, A., Glauben, R., Siegmund, B., & Steinhoff, U. (2021) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2021.151493 · Cited by 8
Intersections of the microbiome and early neurodevelopment
Vuong, H. E. (2022) · International review of neurobiology · doi:10.1016/bs.irn.2022.06.004 · Cited by 9
Advocating an attack against severe malaria: a cost-effectiveness analysis
Greenhalgh, S., & Chandwani, V. (2020) · BMC Public Health · doi:10.1186/s12889-019-8141-y · Cited by 8
Diet should be a tool for researchers, not a treatment
Turnbaugh, P. J. (2020) · Nature · doi:10.1038/d41586-020-00202-5 · Cited by 8
Mostafa, I., Sthity, R. A., Lamiya, U. H., Tariqujjaman, M., Mahfuz, M., Hasan, S. M. T., & Ahmed, T. (2024) · Children · doi:10.3390/children11010069 · Cited by 7
How nutrient starvation impacts the gut microbiome
Estrela, S., Long, J. Z., & Huang, K. C. (2025) · Nature Microbiology · doi:10.1038/s41564-025-02139-9 · Cited by 11
Kupkova, K., Shetty, S. J., Pray-Grant, M. G., Grant, P. A., Haque, R., Petri, W. A., & Auble, D. (2023) · Clinical Epigenetics · doi:10.1186/s13148-023-01548-z · Cited by 7
Gao, X., Zhao, J., Chen, W., & Zhai, Q. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106867 · Cited by 8
Massaquoi, M. S., & Guillemin, K. J. (2019) · Developmental Cell · doi:10.1016/j.devcel.2019.09.013 · Cited by 7
Social and environmental predictors of gut microbiome age in wild baboonsPreprint
Dasari, M. R., Roche, K. E., Jansen, D., Anderson, J. A., Alberts, S. C., Tung, J., Gilbert, J. A., Blekhman, R., Mukherjee, S., & Archie, E. A. (2024) · eLife · doi:10.7554/elife.102166 · Cited by 8
Paiandeh, M., Maghalian, M., Mohammad‐Alizadeh‐Charandabi, S., & Mirghafourvand, M. (2024) · BMC Pediatrics · doi:10.1186/s12887-024-05179-y · Cited by 12
The human gut microbiome in enteric infections: from association to translation
Yin, Q., Gupta, S., Muller, E., & Almeida, A. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2612836 · Cited by 8
Worming into infancy: Exploring helminth-microbiome interactions in early life
Bogza, A., King, I. L., & Maurice, C. F. (2024) · Cell Host & Microbe · doi:10.1016/j.chom.2024.04.009 · Cited by 6
Microbiome and pediatric obesity, malnutrition, and nutrition
Valentine, G. C., Hair, A. B., & Martin, C. R. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820602-7.00008-8 · Cited by 6
Brüssow, H. (2023) · Microbiome Research Reports · doi:10.20517/mrr.2022.20 · Cited by 7
Yang, J., Qin, K., Wang, Q., & Yang, X. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130677 · Cited by 7
Persistent delay in maturation of the developing gut microbiota in infants with cystic fibrosisPreprint
Salerno, P., Verster, A. J., Valls, R. A., Barrack, K. E., Price, C. E., Madan, J. C., O’Toole, G. A., & Ross, B. D. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.02.539134 · Cited by 6
Disruption and adaptation: infant gut microbiota’s dynamic response to SARS-CoV-2 infection
Zhu, L., Zhao, L., Zhu, Y., Xu, X., Lin, J., Duan, Y., Long, L., Wu, Y.-Y., Xu, W.-J., Chen, J., et al. (2025) · Microbiome · doi:10.1186/s40168-025-02029-6 · Cited by 5
B vitamins as adjunct therapies for depressive disorder
Zheng, Z.-Q., Shen, L., Zhao, L., & Ji, H. (2025) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2025.04.007 · Cited by 6
Pediatric and adult point of view on the gut-kidney axis in CKD
Holle, J. B., Behrens, F., & Koppe, L. (2025) · Pediatric Nephrology · doi:10.1007/s00467-025-06780-8 · Cited by 6
Understanding the influence of the microbiome on childhood infections
Heston, S. M., Hurst, J. H., & Kelly, M. S. (2024) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2024.2340664 · Cited by 5
multiMiAT: an optimal microbiome-based association test for multicategory phenotypes
Sun, H. L., Wang, Y., Xiao, Z. Z., Huang, X., Wang, H., He, T., & Jiang, X. (2023) · Briefings in Bioinformatics · doi:10.1093/bib/bbad012 · Cited by 7
Moderate variations in the human diet impact the gut microbiota in humanized mice
Schoeler, M., Chakaroun, R., Brolin, H., Larsson, I., Perkins, R., Marschall, H., Caesar, R., & Bäckhed, F. (2024) · Acta Physiologica · doi:10.1111/apha.14100 · Cited by 5
Pediatric Digestive Health and the Gut Microbiome: Existing Therapies and a Look to the Future
Saul, S. A., Füssel, J., & Runde, J. (2021) · Pediatric Annals · doi:10.3928/19382359-20210720-01 · Cited by 5
Xu, R., Liu, P., Zhang, T., Wu, Q., Zeng, M., Ma, Y., Jin, X., Xu, J., Zhang, Z., & Zhang, C. (2020) · medRxiv · doi:10.1101/2020.07.13.20152181 · Cited by 5
Growth and the Microbiome — Integrating Global Health with Basic Science
Xavier, R. J. (2020) · New England Journal of Medicine · doi:10.1056/nejme2017496 · Cited by 5
Microbial Nourishment for Undernutrition
Garrett, W. S. (2021) · New England Journal of Medicine · doi:10.1056/nejme2104212 · Cited by 5
The gut microbiome and early-life growth in a population with high prevalence of stuntingPreprint
Robertson, R. C., Edens, T. J., Carr, L., Mutasa, K., Evans, C., Gough, E. K., Geum, H. M., Baharmand, I., Gill, S. K., Ntozini, R., et al. (2022) · medRxiv · doi:10.1101/2022.04.19.22273587 · Cited by 5
Stunting is associated with persistent and transferable alterations in the gut microbiome
Amimo, J. O., Kunyanga, C. N., Raev, S. A., Kick, M. K., Micheal, H., Saif, L. J., & Vlasova, A. N. (2025) · Gut Pathogens · doi:10.1186/s13099-025-00723-2 · Cited by 5
Jamil, Z., Hanson, G. F., Iqbal, J., Moreau, G. B., Iqbal, N. T., Ahmed, S., Hotwani, A., Kabir, F., Umrani, F. A., Sadiq, K., et al. (2025) · JCI Insight · doi:10.1172/jci.insight.188993 · Cited by 4
Innovations in Addressing Pediatric Diarrhea in Low Resource Settings
Jumani, R. S., Spector, J., Izadnegahdar, R., Kelly, P. M., Diagana, T. T., & Manjunatha, U. H. (2019) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.9b00315 · Cited by 4
Establishing microbiome causality to tackle malnutrition
Walter, J. (2024) · Nature Microbiology · doi:10.1038/s41564-024-01653-6 · Cited by 4
Dai, D. L., Petersen, C., & Turvey, S. E. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1455503 · Cited by 7
Phiri, T. N., Weatherill, J. W., Sánchez, E. M., Serrano-Contreras, J. I., Melvin, C., Kunaka, M., Chisenga, I., Ngalande, P., Mweetwa, M. N., Besa, E. C., et al. (2025) · F1000Research · doi:10.12688/f1000research.154471.2 · Cited by 4
Social and environmental predictors of gut microbiome age in wild baboons
Dasari, M. R., Roche, K. E., Jansen, D., Anderson, J. A., Alberts, S. C., Tung, J., Gilbert, J. A., Blekhman, R., Mukherjee, S., & Archie, E. A. (2025) · eLife · doi:10.7554/elife.102166.3 · Cited by 4
Neurodevelopment and the gut microbiome
Oliphant, K., & Lu, J. N. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820602-7.00006-4 · Cited by 6
Li, H., Zhang, W., Gao, Y., Tian, X., Chu, Z., Cai, Y., & Wang, L. (2021) · Aquaculture Research · doi:10.1111/are.15605 · Cited by 4
Underdevelopment of gut microbiota in failure to thrive infants of up to 12 months of age
Zhang, M., Miao, D., Ma, Q., Chen, T., Wang, T., Yan, S., Zhu, W., Zhou, F., He, J., & Kuang, X. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.1049201 · Cited by 5
Microbiota and growth among infants and children in low-income and middle-income settings
Njunge, J. M., & Walson, J. L. (2023) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000927 · Cited by 4
Probiotic Supplementation for Promotion of Growth in Children: A Systematic Review and Meta-AnalysisPreprint
Catania, J., Pandit, N. G., Ehrlich, J. M., Zaman, M., Stone, E., Franceschi, C., Smith, A. A., Tanner‐Smith, E. E., Zackular, J. P., Bhutta, Z. A., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3924143 · Cited by 4
Prevotella copri -related effects of a therapeutic food for malnutritionPreprint
Chang, H.-W., Lee, E. M., Wang, W. Y., Zhou, C., Pruss, K. M., Henrissat, S., Chen, R. Y., Kao, C.-Y., Hibberd, M. C., Lynn, H. M., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.11.553030 · Cited by 4
Current progress on the microbial therapies for acute liver failure
Huang, J., Xu, T., Quan, G., Li, Y., Yang, X., & Xie, W.-R. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1452663 · Cited by 3
Marconi, S. D., Sinha, B., Apte, A. A., Sasikumar, M., Aggarwal, G., Chabukswar, R., Vasudevan, A., Miyandad, Z., Pandian, S., Shambharkar, P., et al. (2024) · Journal of Nutrition · doi:10.1016/j.tjnut.2024.11.001 · Cited by 3
Shahzad, M. A., Ismail, M., Misselwitz, B., Saidal, A., Andrews, S. C., Iqbal, K., Akarsu, H., & Nabhani, Z. A. (2025) · F1000Research · doi:10.12688/f1000research.158415.2 · Cited by 3
Metadata
- Authors
- Gehrig, J. L., Venkatesh, S., Chang, H.-W., Hibberd, M. C., Kung, V. L., Cheng, J., Chen, R. Y., Subramanian, S., Cowardin, C. A., Meier, M. F., O’Donnell, D., Talcott, M., Spears, L. D., Semenkovich, C. F., Henrissat, B., Giannone, R. J., Hettich, R. L., Ilkayeva, O., Muehlbauer, M., Newgard, C. B., Sawyer, C., Head, R. D., Rodionov, D. A., Arzamasov, A. A., Leyn, S. A., Osterman, A. L., Hossain, M. I., Islam, M., Choudhury, N., Sarker, S. A., Huq, S., Mahmud, I., Mostafa, I., Mahfuz, M., Barratt, M. J., Ahmed, T., & Gordon, J. I.
- Affiliations
- Washington University in St. Louis (US)
- Centre National de la Recherche Scientifique (FR)
- Oak Ridge National Laboratory (US)
- Duke Medical Center (US)
- Russian Academy of Sciences (RU)
- Sanford Burnham Prebys Medical Discovery Institute (US)
- International Centre for Diarrhoeal Disease Research (BD)
- Corresponding author
- Gehrig, Jeanette L.
- Venkatesh, Siddarth
- Chang, Hao-Wei
- Gordon, Jeffrey I.
- ORCID
- Gehrig, Jeanette L.
- Venkatesh, Siddarth
- Chang, Hao-Wei
- Hibberd, Matthew C.
- Kung, Vanderlene L.
- Cheng, Jiye
- Chen, Robert Y.
- Subramanian, Sathish
- Cowardin, Carrie A.
- O’Donnell, David
- Talcott, Michael
- Spears, Larry D.
- Semenkovich, Clay F.
- Henrissat, Bernard
- Giannone, Richard J.
- Hettich, Robert L.
- Ilkayeva, Olga
- Muehlbauer, Michael
- Newgard, Christopher B.
- Sawyer, Christopher
- Head, Richard D.
- Rodionov, Dmitry A.
- Arzamasov, Aleksandr A.
- Leyn, Semen A.
- Osterman, Andrei L.
- Hossain, Md Iqbal
- Islam, Munirul
- Choudhury, Nuzhat
- Sarker, Shafiqul Alam
- Huq, Sayeeda
- Mahmud, Imteaz
- Mostafa, Ishita
- Mahfuz, Mustafa
- Barratt, Michael J.
- Ahmed, Tahmeed
- Gordon, Jeffrey I.
- Venue
- Science
- Published
- 2019-07-12
- Volume
- 365
- Issue
- 6449
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC6683325
- OpenAlex
- W2959398154
- Cited by
- 431
- References
- 120
- Citations by year
- 2026: 38 · 2025: 51 · 2024: 56 · 2023: 57 · 2022: 72 · 2021: 82 · 2020: 56 · 2019: 16
- FWCI
- 18.70
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Science (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Digital Commons@Becker (Washington University School of Medicine) (submittedVersion, cc-by)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion, cc-by)
- HAL (submittedVersion, cc-by)
- Bristol Research (University of Bristol) (submittedVersion, other-oa)
- Greater South Information System
- Funders
- National Institutes of Health (GM007200, P30AR057235)
- Bill and Melinda Gates Foundation (OPP1134649)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- gut microbiota, child undernutrition, severe acute malnutrition, moderate acute malnutrition, gnotobiotic mice, gnotobiotic pigs, plasma biomarkers, bone formation, brain development, immune function, Bangladeshi children
- MeSH terms
- Gastrointestinal Microbiome, Host Microbial Interactions, Animals, Bangladesh, Blood Proteins, Child, Preschool, Germ-Free Life, Humans, Infant, Infant Nutritional Physiological Phenomena, Child Nutrition Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review