Ilkayeva, Olga

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, J., Duncan, A. E., Kau, A. L., Griffin, N. W., Lombard, V., Henrissat, B., Bain, J. R., et al. (2013) · Science

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 3,788

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

Newgard, C. B., An, J., Bain, J. R., Muehlbauer, M. J., Stevens, R. D., Lien, L. F., Haqq, A. M., Shah, S. H., Arlotto, M., Slentz, C. A., et al. (2009) · Cell Metabolism

Diet, Metabolism, and DiseaseAdipokines, Inflammation, and Metabolic Diseases

Cited by 3,165

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Koves, T. R., Ussher, J. R., Noland, R. C., Slentz, D., Mosedale, M., Ilkayeva, O., Bain, J., Stevens, R., Dyck, J. R. B., Newgard, C. B., et al. (2008) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 1,990

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Hirschey, M. D., Shimazu, T., Goetzman, E., Jing, E., Schwer, B., Lombard, D. B., Grueter, C. A., Harris, C., Biddinger, S., Ilkayeva, O. R., et al. (2010) · Nature

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 1,687

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

Tan, M., Peng, C., Anderson, K. A., Chhoy, P., Xie, Z., Dai, L., Park, J., Chen, Y., Huang, H., Zhang, Y., et al. (2014) · Cell Metabolism

Sirtuins and Resveratrol in MedicineCancer-related gene regulation

Cited by 844

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition

Charbonneau, M. R., O’Donnell, D., Blanton, L. V., Totten, S. M., Davis, J. C. C., Barratt, M. J., Cheng, J., Guruge, J., Talcott, M., Bain, J. R., et al. (2016) · Cell

Infant Nutrition and HealthGut microbiota and health

Cited by 606

Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

Yurdagul, A., Subramanian, M., Wang, X., Crown, S. B., Ilkayeva, O. R., Darville, L., Kolluru, G. K., Rymond, C. C., Gerlach, B. D., Zheng, Z., et al. (2020) · Cell Metabolism

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 525

Peroxisome Proliferator-activated Receptor-γ Co-activator 1α-mediated Metabolic Remodeling of Skeletal Myocytes Mimics Exercise Training and Reverses Lipid-induced Mitochondrial Inefficiency

Koves, T. R., Li, P., An, J., Akimoto, T., Slentz, D., Ilkayeva, O., Dohm, G. L., Yan, Z., Newgard, C. B., & Muoio, D. M. (2005) · Journal of Biological Chemistry

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 464

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

Gehrig, J. L., Venkatesh, S., Chang, H.-W., Hibberd, M. C., Kung, V. L., Cheng, J., Chen, R. Y., Subramanian, S., Cowardin, C. A., Meier, M. F., et al. (2019) · Science

Gut microbiota and healthChild Nutrition and Water Access

Cited by 431

Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

Muoio, D. M., Noland, R. C., Kovalik, J.-P., Seiler, S. E., Davies, M. N., DeBalsi, K. L., Ilkayeva, O. R., Stevens, R. D., Kheterpal, I., Zhang, J., et al. (2012) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 372

The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos

Sommer, F., Ståhlman, M., Ilkayeva, O., Arnemo, J. M., Kindberg, J., Josefsson, J., Newgard, C. B., Fröbert, O., & Bäckhed, F. (2016) · Cell Reports

Gut microbiota and healthAnimal Nutrition and Physiology

Cited by 370

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase

White, P. J., McGarrah, R. W., Grimsrud, P. A., Tso, S.-C., Yang, W.-H., Haldeman, J. M., Grenier-Larouche, T., An, J., Lapworth, A. L., Astapova, I., et al. (2018) · Cell Metabolism

Biochemical Acid Research StudiesMetabolism, Diabetes, and Cancer

Cited by 365

Leptin therapy in insulin-deficient type I diabetes

Wang, M.-Y., Chen, L., Clark, G. O., Lee, Y., Stevens, R. D., Ilkayeva, O. R., Wenner, B. R., Bain, J. R., Charron, M. J., Newgard, C. B., et al. (2010) · Proceedings of the National Academy of Sciences

Diabetes Management and ResearchRegulation of Appetite and Obesity

Cited by 327

SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion

Anderson, K. A., Huynh, F. K., Fisher-Wellman, K., Stuart, J. D., Peterson, B. S., Douros, J. D., Wagner, G. R., Thompson, J. W., Madsen, A. S., Green, M. F., et al. (2017) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAutophagy in Disease and Therapy

Cited by 326

Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control

Noland, R. C., Koves, T. R., Seiler, S. E., Lum, H., Lust, R. M., Ilkayeva, O., Stevens, R. D., Hegardt, F. G., & Muoio, D. M. (2009) · Journal of Biological Chemistry

Metabolism and Genetic DisordersAdipose Tissue and Metabolism

Cited by 317

A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation

Wagner, G. R., Bhatt, D. P., O’Connell, T. M., Thompson, J. W., Dubois, L. G., Backos, D. S., Yang, H., Mitchell, G. A., Ilkayeva, O. R., Stevens, R. D., et al. (2017) · Cell Metabolism

Cancer, Lipids, and MetabolismAdvanced Proteomics Techniques and Applications

Cited by 258

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance

Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., et al. (2012) · Cell Metabolism

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 245

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Softic, S., Meyer, J. G., Wang, G.-X., Gupta, M. K., Batista, T. M., Lauritzen, H. P. M. M., Fujisaka, S., Serra, D., Herrero, L., Willoughby, J., et al. (2019) · Cell Metabolism

Diet, Metabolism, and DiseaseMetabolism, Diabetes, and Cancer

Cited by 227

Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation

Michalek, R. D., Gerriets, V. A., Nichols, A. G., Inoue, M., Kazmin, D., Chang, C.-Y., Dwyer, M. A., Nelson, E. R., Pollizzi, K. N., Ilkayeva, O., et al. (2011) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 216

Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal

Burkewitz, K., Morantte, I., Weir, H. J. M., Yeo, R., Zhang, Y., Huynh, F. K., Ilkayeva, O. R., Hirschey, M. D., Grant, A. R., & Mair, W. B. (2015) · Cell

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 186

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells

Ferdaoussi, M., Dai, X., Jensen, M. V., Wang, R., Peterson, B. S., Huang, C., Ilkayeva, O., Smith, N., Miller, N., Hajmrle, C., et al. (2015) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 169

Prior dietary practices and connections to a human gut microbial metacommunity alter responses to diet interventions

Griffin, N. W., Ahern, P. P., Cheng, J., Heath, A. C., Ilkayeva, O., Newgard, C. B., Fontana, L., & Gordon, J. I. (2017) · Cell Host & Microbe

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 164

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77

Chao, L. C., Wroblewski, K., Zhang, Z., Pei, L., Vergnes, L., Ilkayeva, O. R., Ding, S. Y., Reue, K., Watt, M. J., Newgard, C. B., et al. (2009) · Diabetes

Nuclear Receptors and SignalingMetabolism, Diabetes, and Cancer

Cited by 154

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase

Ussher, J. R., Koves, T. R., Jaswal, J. S., Zhang, L., Ilkayeva, O., Dyck, J. R. B., Muoio, D. M., & Lopaschuk, G. D. (2009) · Diabetes

Cardiovascular Function and Risk FactorsCancer, Lipids, and Metabolism

Cited by 135