Cancer modeling meets human organoid technology

Cited by (938)

Items 301–400 of 938

  1. Microfluidic Platform for Generating and Releasing Patient‐Derived Cancer Organoids with Diverse Shapes: Insight into Shape‐Dependent Tumor Growth
    Sina Kheiri, Ilya Yakavets, Jennifer Cruickshank, Fatemeh Ahmadi, Hal K. Berman, David W. Cescon, Edmond W. K. Young, Eugenia Kumacheva · 2024 · Advanced Materials
  2. Current status and future outlook for patient‐derived cancer models from a rare cancer research perspective
    Tadashi Kondo · 2020 · Cancer Science
  3. Personalized treatment for hepatocellular carcinoma in the era of targeted medicine and bioengineering
    Hang Sun, Huayu Yang, Yilei Mao · 2023 · Frontiers in Pharmacology
  4. Cutoff value of IC50 for drug sensitivity in patient-derived tumor organoids in colorectal cancer
    Yuting Tang, Ting Wang, Yaowen Hu, Hongli Ji, Botao Yan, Xiarong Hu, Yunli Zeng, Yifan Hao, Weisong Xue, Zexin Chen et al. · 2023 · iScience
  5. Mesenchymal Stem Cells Inhibits Migration and Vasculogenic Mimicry in Nasopharyngeal Carcinoma Via Exosomal MiR-125a
    Fangzhu Wan, Haojiong Zhang, Jiyi Hu, Li Chen, Shikai Geng, Lin Kong, Jiade Jay Lu · 2022 · Frontiers in Oncology
  6. Spheroids and organoids derived from colorectal cancer as tools for in vitro drug screening
    Sahira Syamimi Ahmad Zawawi, Elyn Amiela Salleh, Marahaini Musa · 2024 · Exploration of Targeted Anti-tumor Therapy
  7. Applications of Organoids in Advancing Drug Discovery and Development
    Indiwari Gopallawa, Charu Gupta, Rayan Jawa, Arya Cyril, Vibha Jawa, Narendra B. Chirmule, Vikramsingh Gujar · 2024 · Journal of Pharmaceutical Sciences
  8. Stem Cells and Organoid Technology in Precision Medicine in Inflammation: Are We There Yet?
    Florian Tran, Christine Klein, Alexander Arlt, Simon Imm, Evelyn Knappe, Alison Simmons, Philip C Rosenstiel, Philip Seibler · 2020 · Frontiers in Immunology
  9. Neutrophil-mediated clinical nanodrug for treatment of residual tumor after focused ultrasound ablation
    Jian Shen, Junnian Hao, Yini Chen, Hairong Liu, Jianrong Wu, Bing Quan Hu, Yan Wang, Yuanyi Zheng, Xiaojun Cai · 2021 · Journal of Nanobiotechnology
  10. Application Progress of Organoids in Colorectal Cancer
    Lianxiang Luo, Yucui Ma, Yilin Zheng, Jiating Su, Guoxin Huang · 2022 · Frontiers in Cell and Developmental Biology
  11. 3D imaging for driving cancer discovery
    Ravian L. van Ineveld, Esmée J. van Vliet, Ellen J. Wehrens, María Alieva, Anne C. Rios · 2022 · The EMBO Journal
  12. Cell Culture Model Evolution and Its Impact on Improving Therapy Efficiency in Lung Cancer
    Viviana Roman, Mirela Antonela Mihaila, Nicoleta Radu, Stefania Marineata, Carmen Cristina Diaconu, Marinela Bostan · 2023 · Cancers
  13. Three-Dimensional Printed Stamps for the Fabrication of Patterned Microwells and High-Throughput Production of Homogeneous Cell Spheroids
    Tomas Gonzalez‐Fernandez, Alejandro J. Tenorio, Jonathan Kent Leach · 2020 · 3D Printing and Additive Manufacturing
  14. The Evolution of Anticancer 3D In Vitro Models: The Potential Role of Machine Learning and AI in the Next Generation of Animal-Free Experiments
    Carolina Momoli, Beatrice Costa, Lorenzo Lenti, Matilde Tubertini, Marco Parenti, Elisa Martella, Greta Varchi, Claudia Ferroni · 2025 · Cancers
  15. Combining molecular characteristics and therapeutic analysis of PDOs predict clinical responses and guide PDAC personalized treatment
    Peng Li, Minli Huang, Mengyao Li, Gen Li, Yifan Ma, Yong Xiang Zhao, Xiaowu Wang, Yongbin Zhang, Changhong Shi · 2025 · Journal of Experimental & Clinical Cancer Research
  16. Proton-Sensing G Protein-Coupled Receptors: Detectors of Tumor Acidosis and Candidate Drug Targets
    Paul A. Insel, Krishna Sriram, Cristina Salmerón, Shu Z. Wiley · 2020 · Future Medicinal Chemistry
  17. Interstitial Lung Disease in Patients With Systemic Sclerosis: Toward Personalized-Medicine-Based Prediction and Drug Screening Models of Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD)
    Padmini P. S. J. Khedoe, Emiel R. Marges, Pieter Sicco Hiemstra, Maarten K. Ninaber, Miranda Geelhoed · 2020 · Frontiers in Immunology
  18. Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug‐Resistant Model and Genome‐Wide siRNA Screening
    Fangyuan Shao, Xueying Lyu, Kai Miao, Lisi Xie, Haitao Wang, Hao Xiao, Jie Li, Qiang Chen, Ren‐Bo Ding, Ping Chen et al. · 2020 · Advanced Science
  19. 3D printed porous microgel for lung cancer cells culture in vitro
    Qipeng Hu, Xuan Liu, Haofan Liu, Ling Yang, Xin Yuan, Yuwen Chen, Wenbi Wu, Jing Cong Luo, Jianlin Long, Meijuan Huang et al. · 2021 · Materials & Design
  20. Specific metabolic response of patient-derived organoids to curcumin of colorectal cancer
    Lin Chen, Zhihui Dai, Chengyang Ge, Dong Huang, Xi Zhou, Kailing Pan, Wenxia Xu, Jianfei Fu, Jin lin Du · 2022 · Journal of Chromatography B
  21. Role of in vitro two-dimensional (2D) and three-dimensional (3D) cell culture systems for ADME-Tox screening in drug discovery and development: a comprehensive review
    Venkatesh Chunduri, Srinivas Maddi · 2022 · ADMET & DMPK
  22. Emerging strategy towards mucosal healing in inflammatory bowel disease: what the future holds?
    Min Wang, Jingyan Shi, Chao Yu, Xinyi Zhang, Gaoxin Xu, Ziyan Xu, Yong Ma · 2023 · Frontiers in Immunology
  23. Organoids in domestic animals: with which stem cells?
    Bertrand Pain · 2021 · Veterinary Research
  24. Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening
    Meghan J. O’Melia, Adriana Mulero‐Russe, Jihoon Kim, Alyssa F. Pybus, Deborah DeRyckere, Levi Benjamin Wood, Douglas K. Graham, Edward A. Botchwey, Andrés J. Garcı́a, Susan N. Thomas · 2022 · Advanced Materials
  25. Translational organoid technology – the convergence of chemical, mechanical, and computational biology
    Weijie Zhang, Jiawei Li, Jiaqi Zhou, Abhay Rastogi, Shaohua Ma · 2022 · Trends in biotechnology
  26. Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer
    Sadanori Watanabe, Akitada Yogo, Tsuguteru Otsubo, Hiroki Umehara, Jun Oishi, Toru Kodo, Toshihiko Masui, Shigeo Takaishi, Hiroshi Seno, Shinji Üemoto et al. · 2022 · BMC Cancer
  27. Unveiling Epigenetic Vulnerabilities in Triple-Negative Breast Cancer through 3D Organoid Drug Screening
    Xinxin Rao, Zhibin Qiao, Yang Yang, Yun Deng, Zhen Zhang, Xiaoli Yu, Xiaomao Guo · 2024 · Pharmaceuticals
  28. Colorectal carcinoma peritoneal metastases-derived organoids: results and perspective of a model for tailoring hyperthermic intraperitoneal chemotherapy from bench-to-bedside
    Luca Varinelli, Davide Battistessa, Marcello Guagliò, Susanna Zanutto, Oscar Illescas, Ewelina Lorenc, Federica Pisati, Shigeki Kusamura M. D, Laura Cattaneo, Giovanna Sabella et al. · 2024 · Journal of Experimental & Clinical Cancer Research
  29. New Scenarios in Pharmacological Treatments of Head and Neck Squamous Cell Carcinomas
    Cristina Porcheri, Thimios A. Mitsiadis · 2021 · Cancers
  30. Modeling the Effects of Maternal Diabetes on the Developing Human Heart Using Pluripotent Stem Cell–Derived Heart Organoids
    Yonatan R. Lewis‐Israeli, Mishref Abdelhamid, Isoken Nicholas Olomu, Aitor Aguirre · 2022 · Current Protocols
  31. Organoids technology for advancing the clinical translation of cancer nanomedicine
    Dong‐Kun Zhao, Jie Liang, Xiao‐Yi Huang, Song Shen, Jun Wang · 2023 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  32. Antitumor effect of luteolin proven by patient‐derived organoids of gastric cancer
    Xinyu Hao, Ming Zu, Jing Ning, Xin Zhou, Yueqing Gong, Xiurui Han, Qiao Meng, Dong Li, Shigang Ding · 2023 · Phytotherapy Research
  33. In Vitro Models of Head and Neck Cancer: From Primitive to Most Advanced
    Irina V. Arutyunyan, Enar D. Jumaniyazova, А. В. Макаров, Timur Fatkhudinov · 2023 · Journal of Personalized Medicine
  34. Bioprinted research models of urological malignancy
    Guanyi Wang, Xiongmin Mao, Wang Wang, Wang Xiaolong, Sheng Li, Zijian Wang · 2024 · Exploration
  35. Hypoxia at 3D organoid establishment selects essential subclones within heterogenous pancreatic cancer
    Koichiro Kumano, Hiromitsu Nakahashi, Pakavarin Louphrasitthiphol, Yukihito Kuroda, Yoshihiro Miyazaki, Osamu Shimomura, Shinji Hashimoto, Yoshimasa Akashi, Bryan James Mathis, Jaejeong Kim et al. · 2024 · Frontiers in Cell and Developmental Biology
  36. Segmentation and Multi-Timepoint Tracking of 3D Cancer Organoids from Optical Coherence Tomography Images Using Deep Neural Networks
    Francesco Branciforti, Massimo Salvi, Filippo D’Agostino, Francesco Marzola, Sara Cornacchia, Maria Olimpia De Titta, Girolamo Mastronuzzi, Isotta Meloni, Miriam Moschetta, Niccolò Porciani et al. · 2024 · Diagnostics
  37. Leveraging Patient-Derived Organoids for Personalized Liver Cancer Treatment
    Jianhua Rao, Chao Song, Yangyang Hao, Zaozao Chen, Sidu Feng, Shihui Xu, Xiaoyue Wu, Zhengfeng Xuan, Ye Fan, Wenzhu Li et al. · 2024 · International Journal of Biological Sciences
  38. Organoids for the Study of Liver Cancer
    Haichuan Wang, Diego Francesco Calvisi, Xin Chen · 2021 · Seminars in Liver Disease
  39. Organoid Models of SARS-CoV-2 Infection: What Have We Learned about COVID-19?
    Bang M. Tran, Georgia Deliyannis, Abderrahman Hachani, Linda Earnest, Joseph Torresi, Elizabeth Vincan · 2022 · Organoids
  40. Revisiting characteristics of oncogenic extrachromosomal DNA as mobile enhancers on neuroblastoma and glioma cancers
    Mohsen Karami Fath, Nastaran Karimfar, Andarz Fazlollahpour Naghibi, Shahriyar Shafa, Melika Ghasemi Shiran, Mehran Ataei, Hossein Dehghanzadeh, Mohsen Nabi‐Afjadi, Tahereh Ghadiri, Zahra Payandeh et al. · 2022 · Cancer Cell International
  41. Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
    Åsmund Flobak, Sigrid Strand Skånland, Eivind J. Hovig, Kjetil Taskén, Hege Giercksky Russnes · 2022 · Trends in Pharmacological Sciences
  42. Constructing 3D In Vitro Models of Heterocellular Solid Tumors and Stromal Tissues Using Extrusion-Based Bioprinting
    Salvador Flores-Torres, Tao Jiang, Jacqueline Kort-Mascort, Yun Kai Yang, Omar Peza-Chavez, Sanjima Pal, Alisia Mainolfi, Lucas Antonio Pardo, Lorenzo Edwin Ferri, Nicholas Bertos et al. · 2023 · ACS Biomaterials Science & Engineering
  43. Patient-derived models facilitate precision medicine in liver cancer by remodeling cell-matrix interaction
    Kaiwen Chen, Yanran Li, Bingran Wang, Xuehan Yan, Yiying Tao, Weizhou Song, Zhifeng Xi, Kang He, Qiang Xia · 2023 · Frontiers in Immunology
  44. Organoids: Construction and Application in Gastric Cancer
    Chengdong Huo, Xiaoxia Zhang, Yanmei Gu, Daijun Wang, Shining Zhang, Tao Liu, Yumin Li, Wenting He · 2023 · Biomolecules
  45. MiRNA and mRNA-Controlled Double-Cascaded Amplifying Circuit Nanosensor for Accurate Discrimination of Breast Cancers in Living Cells, Animals, and Organoids
    Huihui Yang, Dong Chen, Yanfei Zhang, Peixiu Yuan, Ni Xie, Zong Dai · 2024 · Analytical Chemistry
  46. Bridging the organoid translational gap: integrating standardization and micropatterning for drug screening in clinical and pharmaceutical medicine
    Haowei Yang, Jiawei Li, Zitian Wang, Davit Khutsishvili, Jiyuan Tang, Yu Zhu, Yongde Cai, Xiaoyong Dai, Shaohua Ma · 2024 · Life Medicine
  47. A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation
    Tom J. Harryvan, Lukas J.A.C. Hawinkels, Akin Inderson, Jeanin Elise van Hooft, Patrick Micke, J.S. Johansen, Tom van Wezel, Stijn Crobach, Victor M. Baart, Brook Quist et al. · 2022 · Gastro Hep Advances
  48. Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution
    Guanglong Chen, Ting Gong, Zhe Wang, Zeyu Wang, Xiaolin Lin, Sunrui Chen, Chu Sun, Weijie Zhao, Ye Kong, Huihan Ai et al. · 2022 · Cellular Oncology
  49. Organoids: Principle, application and perspective
    Kaizheng Liu, Xinyi Fang, Abdellah Aazmi, Qingzhe Wang, Xiaofeng Gong, Zhengkun Chen, Minghao Qin, Chunyi Pu, Ying Zhao, Xiaozhong Qiu et al. · 2024 · The Innovation Life
  50. Robotic micromanipulation for patterned and complex organoid biofabrication
    Mingsi Tong, Gang Huang, Songlin Zhuang, Xinghu Yu, Delin Hu, Weiyang Lin, Yang Wu, Yu‐Chen Chen, Shijia Cheng, Meng Jiang et al. · 2025 · Science Advances
  51. In vitro models as tools for screening treatment options of head and neck cancer
    Barbara Seliger, Ahmed Al‐Samadi, Bo Yang, Tuula Anneli Salo, Claudia Wickenhauser · 2022 · Frontiers in Medicine
  52. Patient-derived parathyroid organoids as a tracer and drug-screening application model
    Milou E. Noltes, Luc H. J. Sondorp, Laura Kracht, Ines Farinha Antunes, René Wardenaar, Wendy Kelder, Annelies Kemper, Wiktor Szymański, Wouter T. Zandee, Liesbeth Jansen et al. · 2022 · Stem Cell Reports
  53. Engineering Heterogeneous Tumor Models for Biomedical Applications
    Zhuhao Wu, Danqing Huang, Jinglin Wang, Yuanjin Zhao, Weijian Sun, Xian Shen · 2023 · Advanced Science
  54. Organoids: An Emerging Precision Medicine Model for Prostate Cancer Research
    Mohammad Waseem, Bi‐Dar Wang · 2024 · International Journal of Molecular Sciences
  55. Initiation of Cancer: The Journey From Mutations in Somatic Cells to Epigenetic Changes in Tissue-resident VSELs
    Deepa Bhartiya, Sherif Raouf, Kshama Pansare, Anish Tripathi, Ashish Tripathi · 2024 · Stem Cell Reviews and Reports
  56. Trends in organ-on-a-chip for pharmacological analysis
    Xinmei Xu, Suet Cheung, Xiaomeng Jia, Gang Fan, Yongjian Ai, Yi Zhang, Qionglin Liang · 2024 · TrAC Trends in Analytical Chemistry
  57. Advances of immune-checkpoint inhibition of CTLA-4 in pancreatic cancer
    Ran Ni, Zhiming Hu, Ran Tao · 2024 · Biomedicine & Pharmacotherapy
  58. Adult tissue-resident stem cells—fact or fiction?
    Deepa Bhartiya · 2021 · Stem Cell Research & Therapy
  59. The potential application of organoids in breast cancer research and treatment
    Nasim Ebrahimi, Alireza Nasr Esfahani, Setare Samizade, Atena Mansouri, Masoud Ghanaatian, Samaneh Adelian, Vida Shadman-Manesh, Michael Richard Hamblin · 2021 · Human Genetics
  60. Hybrid computational models of multicellular tumour growth considering glucose metabolism
    Inês G. Gonçalves, José Manuel García‐Aznar · 2023 · Computational and Structural Biotechnology Journal
  61. Advances in organoid-on-a-chip for recapitulation of human physiological events
    Bum Jun Park, Junseo Park, Sanghun Han, Taeyeon Kwon, Ju Yong Sung, Jigyeong Kim, Moein Safarkhani, Kyung-Hyun Min, Eun-Ho Lee, Sung‐Min Kang et al. · 2025 · Materials Today
  62. Rational design matrix materials for organoid development and application in biomedicine
    Yue Fei Huang, Xiaoyu Zhang, Wanjun Zhang, Jinglong Tang, Jing Liu · 2025 · Regenerative Biomaterials
  63. Phenotype transition of fibroblasts incorporated into patient‐derived oral carcinoma organoids
    Xu Chen, Rui Li, Hui Zhao, Xinmiao Wang, Zhe Shao, Zhengjun Shang · 2021 · Oral Diseases
  64. Pancreatic Cancer Patient-Derived Organoid Platforms: A Clinical Tool to Study Cell- and Non-Cell-Autonomous Mechanisms of Treatment Response
    Geny Piro, Antonio Agostini, Alberto Larghi, Giuseppe Quero, Carmine Carbone, Annachiara Esposito, Gianenrico Rizzatti, Fabia Attili, Sergio Alfieri, Guido Costamagna et al. · 2021 · Frontiers in Medicine
  65. Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation
    Jonathan D. Humphries, Junzhe Zha, Jessica Burns, Janet A. Askari, Christopher Below, Megan R. Chastney, Matt Jones, Aleksandr Mironov, David Knight, Derek A O'Reilly et al. · 2022 · Matrix Biology
  66. Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells
    Dieuwke Louise Marvin, Li You, Laura Bornes, Maarten van Dinther, Niek A. Peters, Hao Dang, Sarah K. Hakuno, Marten Hornsveld, Onno Kranenburg, Jacco van Rheenen et al. · 2022 · Cancers
  67. Advances in liver organoids: model systems for liver disease
    Jaeseo Lee, Seon Ju Mun, Yongbo Shin, Seonbhin Lee, Myung Jin Son · 2022 · Archives of Pharmacal Research
  68. Breast cancer cells interact with tumor-derived extracellular matrix in a molecular subtype-specific manner
    Qiuwen Tan, Li Xu, Junhui Zhang, Liang‐Ju Ning, Yanling Jiang, Tao He, Jingcong Luo, Jie Chen, Qing Lv, Xiaoqin Yang et al. · 2023 · Biomaterials Advances
  69. Recent advances of three-dimensional bioprinting technology in hepato-pancreato-biliary cancer models
    Xiaomei Zhuang, Gang Deng, Xiaoying Wu, Juping Xie, Dong Li, Songlin Peng, Di Tang, Guoying Zhou · 2023 · Frontiers in Oncology
  70. Establishing mouse and human oral esophageal organoids to investigate the tumor immune response
    Yuan Jiang, Hua Zhao, Shuai Kong, Dan Zhou, Jinxiu Dong, Yulan Cheng, Shuo Zhang, Fei Wang, Andrew Kalra, Nina Yang et al. · 2024 · Disease Models & Mechanisms
  71. A pancreatic cancer organoid-in-matrix platform shows distinct sensitivities to T cell killing
    Anton Lahusen, Jierui Cai, Reinhold Schirmbeck, Anton Wellstein, Alexander Kleger, Thomas Theodor Werner Seufferlein, Tim Eiseler, Yuan‐Na Lin · 2024 · Scientific Reports
  72. The use of patient-derived xenografts and patient-derived organoids in the search for new therapeutic regimens for pancreatic carcinoma. A review
    Emin Gayibov, Tomas Sychra, Alžběta Spálenková, Pavel Souček, Martin Oliverius · 2024 · Biomedicine & Pharmacotherapy
  73. Emerging Biomimetic Materials for Studying Tumor and Immune Cell Behavior
    Logan A. Northcutt, Alejandra Suarez‐Arnedo, Marjan Rafat · 2019 · Annals of Biomedical Engineering
  74. Conversion Therapy of Intrahepatic Cholangiocarcinoma Is Associated with Improved Prognosis and Verified by a Case of Patient-Derived Organoid
    Zhiwei Wang, Yun Jin, Yinghao Guo, Zhenhua Tan, Xiaoxiao Zhang, Dan Ye, Yuanquan Yu, Shu-you Peng, Lei Zheng, Jiangtao Li · 2021 · Cancers
  75. Pancreatic organoids as cancer avatars for true personalized medicine
    Johann Gout, Menar Ekizce, Élodie Roger, Alexander Kleger · 2025 · Advanced Drug Delivery Reviews
  76. Exploring personalized prediction of clinical chemotherapy efficacy and revealing tumor heterogeneity using patient-derived 3D bioprinting gastric cancer models
    Liwei Du, Zicheng Zheng, Kai Zhang, Hang Sun, Yan Lü, Minghao Sun, Mingchang Pang, Shangze Jiang, Yixuan He, Shunda Du et al. · 2025 · Molecular Cancer
  77. Patient-derived xenograft models of BRCA-associated pancreatic cancers
    Talia Golan, Dikla Atias, Chani Stossel, Maria Raitses‐Gurevich · 2021 · Advanced Drug Delivery Reviews
  78. Novel strategy for primary epithelial cell isolation: Combination of hyaluronidase and collagenase I
    Zhewen Hu, Yi‐Ming Chen, Min Gao, Xiaopei Chi, Ying He, Chenguang Zhang, Yue Yang, Yuman Li, Yan Yun Lv, Ying Sheng Huang et al. · 2022 · Cell Proliferation
  79. Engineering the Immune Microenvironment into Organoid Models
    Kathleen A. Luckett, Karuna Ganesh · 2023 · Annual Review of Cancer Biology
  80. Reconstruction of tumor microenvironment via in vitro three-dimensional models
    Zhenzhen Zhou, Jianyu He, Yuan Pang, Wei Yan Sun · 2023 · Biofabrication
  81. Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids
    Wan, Ledong, Kral, Alexander J., Voss, Dillon, Schäfer, Balázs, Sudheendran, Kavitha, Danielsen, Mathias, Caruthers, Marvin H., Krainer, Adrian R. · 2024 · Nucleic Acid Therapeutics
  82. Facilitation of Tumor Stroma-Targeted Therapy: Model Difficulty and Co-Culture Organoid Method
    Qiu-Shi Feng, Xiaofeng Shan, Vicky Yau, Zhigang Cai, Shang Xie · 2025 · Pharmaceuticals
  83. Patient-derived organoid co-culture systems as next-generation models for bladder cancer stem cell research
    Ruici Yang, Shanzhao Wang, Zhichao Li, Cong Yin, Wei Huang, Weiren Huang · 2025 · Cancer Letters
  84. Vascularized organoid-on-a-chip for centimeter-scale organoid cultivation
    X.Y. Gong, Yang Chen, Jianchen Peng, Xiao Lan Ding, Hui Yang, Aaron Gerald Wang, Emmanuel Enoch Dzakah, Bing Tian Zhao · 2025 · Bio-Design and Manufacturing
  85. Patient-derived organotypic tumor spheroids, tumoroids, and organoids: advancing immunotherapy using state-of-the-art 3D tumor model systems
    David J. Bozym, David X. Zheng, Or‐Yam Revach, Amir Reza Aref, Russell William Jenkins · 2025 · Lab on a Chip
  86. Epigenetic reprogramming as the nexus of cancer stemness and therapy resistance: implications for biomarker discovery
    Chu Xin Ng, Shin Yuh Lee, Xin Yi Yap, Yong Hui Wong, Jian Sheng Loh, Kuan Ping Ang, Wen Hwei Lee, Wei Xu, Phelim Voon Chen Yong, Sau Har Lee · 2025 · Discover Oncology
  87. Organoids as a Systems Platform for SCLC Brain Metastasis
    Vito Quaranta, Amanda G. Linkous · 2022 · Frontiers in Oncology
  88. Patient-derived models: Advanced tools for precision medicine in neuroblastoma
    Kristina E. Aaltonen, Katarzyna Radke, Aleksandra Adamska, Alexandra Seger, Adriana Mañas, Daniel Bexell · 2023 · Frontiers in Oncology
  89. Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
    Solveig Pettersen, Geir Frode Øy, Eivind Valen Egeland, Siri Juell, Olav Engebråten, Gunhild Mari Mælandsmo, Lina Prasmickaite · 2023 · Frontiers in Oncology
  90. Microfluidic droplet encapsulation‐guided organoid growth promotes parental tumor phenotype recapitulation
    Weijie Zhang, He Jin, Shitong Lou, Haowei Yang, Xiaoyong Dai, Shaohua Ma · 2023 · International Journal of Cancer
  91. Genetic Alterations of NF-κB and Its Regulators: A Rich Platform to Advance Colorectal Cancer Diagnosis and Treatment
    Faranak Alipourgivi, Aishat Motolani, Ai-Hua Qiu, Wenan Qiang, Guang‐Yu Yang, Shuibing Chen, Tao Lu · 2023 · International Journal of Molecular Sciences
  92. Polydopamine-Based Resveratrol-Hyaluronidase Nanomedicine Inhibited Pancreatic Cancer Cell Invasive Phenotype in Hyaluronic Acid Enrichment Tumor Sphere Model
    Shuo Yu, Lu Zhang, Yanshen Yang, Meijuan Wang, Tingting Liu, Wenwen Ji, Yang Liu, Hao Lv, Yang Zhao, Xi Chen et al. · 2024 · ACS Pharmacology & Translational Science
  93. A platform for rapid patient-derived cutaneous neurofibroma organoid establishment and screening
    Huyen Thi Lam Nguyen, Emily Kohl, Jessica Bade, Stefan E. Eng, Anela Tosevska, Ahmad Al Shihabi, Peyton J. Tebon, Jenny Jimmy Hong, Sarah Dry, Paul Christopher Boutros et al. · 2024 · Cell Reports Methods
  94. Microenvironmental β-TrCP negates amino acid transport to trigger CD8+ T cell exhaustion in human non-small cell lung cancer
    Li Ge, Zhenke Wen, Sidong Xiong · 2025 · Cell Reports
  95. Organoid Models for Cancer Research—From Bed to Bench Side and Back
    Carolin Kastner, Anne Hendricks, Hanna Deinlein, Mohammed K. Hankir, Christoph‐Thomas Germer, Stefanie Schmidt, Armin Wiegering · 2021 · Cancers
  96. Efficacy of temozolomide combined with capecitabine (CAPTEM) on refractory prolactinomas as assessed using an ex vivo 3D spheroid assay
    Atsushi Ishida, Hiroki Shichi, Hidenori Fukuoka, Naoko Inoshita, Wataru Ogawa, Shozo Yamada · 2021 · Pituitary
  97. Diversifying preclinical research tools: expanding patient-derived models to address cancer health disparities
    Nicole Britney Halmai, Luis G. Carvajal‐Carmona · 2022 · Trends in cancer
  98. Barriers and Research Priorities for Implementing Precision Medicine
    David Clement Whitcomb · 2019 · Pancreas
  99. Multiplexed Evaluation of Microdosed Antineoplastic Agents In Situ in the Tumor Microenvironment of Patients with Soft Tissue Sarcoma
    Kenneth R. Gundle, Gary B. Deutsch, Howard J. Goodman, Seth M. Pollack, Matthew J. Thompson, Jessica L. Davis, Mee-Young Lee, Daniel C. Ramirez, William S. Kerwin, Jessica A. Bertout et al. · 2020 · Clinical Cancer Research
  100. Authentication, characterization and contamination detection of cell lines, xenografts and organoids by barcode deep NGS sequencing
    Chen, Xiaobo, Qian, Wubin, Song, Zhenzhen, Li, Qi-Xiang, Guo, Sheng · 2020 · NAR Genomics and Bioinformatics