Cancer modeling meets human organoid technology

Cited by (938)

Items 501–600 of 938

1. Phenethyl Isothiocyanate Enhances the Cytotoxic Effects of PARP Inhibitors in High-Grade Serous Ovarian Cancer Cells
   Yaxun Jia, Min Wang, Xiaolin Sang, Pixu Liu, Jingchun Gao, Kui Jiang, Hai-Ling Margaret Cheng · 2022 · Frontiers in Oncology
2. Co-implantation of Tumor and Extensive Surrounding Tissue Improved the Establishment Rate of Surgical Specimens of Human-Patient Cancer in Nude Mice: Toward the Goal of Universal Individualized Cancer Therapy
   Takuya Murata, CHIHIRO HOZUMI, Yukihiko Hiroshima, Koichiro Shimoya, Atsushi Hongo, Sachiko Inubushi, Hirokazu Tanino, Robert M. Hoffman · 2020 · In Vivo
3. Double-negative T cells: a promising avenue of adoptive cell therapy in transplant oncology
   Zhihang Hu, Modan Yang, Hao Chen, Chiyu He, Zuyuan Lin, Xinyu Yang, Huigang Li, Wei Shen, Di Lu, Xiao Xu · 2023 · Journal of Zhejiang University SCIENCE B
4. Repurposing Metabolic Inhibitors in the Treatment of Colon Adenocarcinoma Patient-Derived Models
   Bora Lee, ChuHee Lee, Hae-Min Moon, Se‐Young Jo, Se Jin Jang, Young‐Ah Suh · 2023 · Cells
5. LncRNAs in melanoma phenotypic plasticity: emerging targets for promising therapies
   Beatriz Cristina Biz Tonin, Castro-Silva Carolina de Sousa, Slack Frank John, Miriam Galvonas Jasiulionis · 2024 · RNA Biology
6. Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2
   Zhilin Sui, Xianxian Wu, Jiaxin Wang, ShihJye Tan, Chao Zhao, Zhentao Yu, Chuanyue Wu, Xiaoxiao Wang, Ling Guo · 2025 · Stem Cell Research & Therapy
7. Osalmid sensitizes clear cell renal cell carcinoma to navitoclax through a STAT3/BCL-XL pathway
   Yizheng Xue, Tianyi Chen, Zehua Ma, Xinyuan Pu, Junyao Xu, Shuanfeng Zhai, Xinxing Du, Yiyi Ji, Marie Celeste Simon, Wei Zhai et al. · 2025 · Cancer Letters
8. Treatment Response to Oncolytic Virus in Patient-Derived Breast Cancer and Hypopharyngeal Cancer Organoids: Evaluation via a Microfluidics Organ-on-a-Chip System
   Yu Sun, Jiaqi Liu, Li Zhu, Fang Huang, Yanbo Dong, Shuang Liu, Si‐Yi Chen, Wei Ji, Jingjing Lu, Liangfa Liu et al. · 2025 · Bioengineering
9. Combinatorial screening of nanomedicines in patient-derived cancer organoids facilitates efficient cancer therapy
   Jie Liang, Dong‐Kun Zhao, Hao-Ming Yin, Tai-Yu Tian, Jian-Kang Kang, Song Shen, Jun Wang · 2025 · Nano Today
10. Organ‐on‐chip for advancing CAR therapy
    Lightson Ngashangva, Sunil Martin · 2025 · Clinical & Translational Immunology
11. Resveratrol suppresses growth and VCAN expression in a Cancer-associated fibroblast-breast Cancer hybrid organoid
    Yixin Shi, Gengxi Cai, Chuling Zhang, Haipeng Li, Yichu Nie, Sifei Yu, Beiying Zhang, Mo‐Li Wu, Weibo Luo, Jia Liu et al. · 2025 · International Immunopharmacology
12. Organoid-based single cell sequencing revealed the lineage evolution during docetaxel treatment in gastric cancer
    Yang Dejun, Xin Zhang, Zunqi Hu, Qiang Sun, Hongbing Fu, Jun Yao, Binbin Zheng, Xin Zhang, Weijun Wang · 2025 · Cancer Letters
13. Interactions Between Non-Coding RNAs and HIF-1alpha in the Context of Colorectal Cancer
    Lianfeng Gong, Haixia Zhang, Ying Liu, Xianwang Wang, Ruohan Xia · 2025 · Biomolecules
14. Patient-derived tumoroids from CIC::DUX4 rearranged sarcoma identify MCL1 as a therapeutic target
    Willemijn B. Breunis, Eva Katharina Brack, Anna C. Ehlers, Ingrid Bechtold, Samanta Kisele, Jakob Wurth, Lieke Mous, Dorita Zabėlė, Fabio D. Steffen, Felina Zahnow et al. · 2025 · Nature Communications
15. AI-identified CD133-targeting natural compounds demonstrate differential anti-tumor effects and mechanisms in pan-cancer models
    Yibo Hou, Zixian Wang, Wenlin Wang, Qing Tang, Yongde Cai, Siyang Yu, J.A. Wang, Yan Xiu, Guo‐Cai Wang, Peter Edward Lobie et al. · 2025 · EMBO Molecular Medicine
16. Pancreatic Cancer Organoids: Modeling Disease and Guiding Therapy
    Franck Morceau, Victoria El‐Khoury, Kyeong Lee, Marc Jean Berna, Yong‐Jun Kwon · 2025 · Cancers
17. Colorectal Air–Liquid Interface Organoids Preserve Tumour-Immune Architecture and Reveal Local Treg Expansion After PD-1 Blockade
    Laura Córdoba, Francisco J. Cueto, Ramón Cantero-Cid, Ravan Moret, Esteban Díaz, Jaime Alvarez-Benayas, Jesús Fernández-Felipe, Jesús Jiménez-Rodríguez, Daniel Arvelo-Rosario, Pablo Mata-Martínez et al. · 2025 · Cancers
18. Engineered Akkermansia muciniphila vesicles for targeted pyroptosis and trained immunity to enhance immunotherapy in hepatocellular carcinoma
    Lanxiang Huang, Yuan Rong, Minghui Guo, Min Liu, Fei Long, Wei Zhong, Yue Hu, Xin He, Jiurong He, Diwei Zheng et al. · 2026 · Cell Reports Medicine
19. Use of patient‐derived tumor organoid platform to predict the benefit of postoperative adjuvant chemotherapy for poor responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancer
    Weisong Xue, Ting Wang, Jiaxin Yao, Wei Wu, Dexin Chen, Botao Yan, Xiaoyu Dong, Yuting Tang, Yunli Zeng, Yueyu He et al. · 2023 · Bioengineering & Translational Medicine
20. 3D-printed scaffold harboring copper ions combined with near-infrared irradiation for local therapy of cancer
    Hao Wei, Dong Chen, Bin Han, Peng Li, Jia Hao, Lizhang Zhu, Hao Yang, Deren Lan, Wei Wei, Haibo Chen et al. · 2023 · iScience
21. Engineering redirected NF-κB/OIP5 expression programs to enhance tumor responses to chemotherapy in bladder cancer
    Binbin Zheng, Liman Niu, Haibo Xu, Yubin Yang, Yanping Chen, Chenguang Wang, Wei Chen, Weiren Huang · 2023 · 中国科学通报：英文版
22. Tissue Engineering Modalities and Nanotechnology
    Hoda A. Elkhenany, M. Abd Elkodous, Steven D. Newby, Azza M. El-Derby, Madhu S Dhar, Nagwa El‐Badri · 2020 · Learning materials in biosciences
23. Convergence of human pluripotent stem cell, organoid, and genome editing technologies
    Lin Wang, Zhaohui Ye, Yoon-Young Jang · 2021 · Experimental Biology and Medicine
24. Prospect of reprogramming replication licensing for cancer drug development
    Isaac Kyei-Barffour, Desmond Omane Acheampong · 2021 · Biomedicine & Pharmacotherapy
25. Endoscopic Ultrasound-Guided Sampling for Personalized Pancreatic Cancer Treatment
    Eisuke Iwasaki, Seiichiro Fukuhara, Masayasu Horibe, Shintaro Kawasaki, Takashi Seino, Yoichi Takimoto, Hiroki Tamagawa, Yujiro Machida, Atsuto Kayashima, Marin Noda et al. · 2021 · Diagnostics
26. Extra chromosomal DNA in different cancers: Individual genome with important biological functions
    Mohsen Karami Fath, Mahsa Akbari Oryani, Arefeh Ramezani, Fatemeh Barjoie Mojarad, Bahman Khalesi, Sina Delazar, Mehran Anjomrooz, Arvin Taghizadeh, S. Taghizadeh, Zahra Payandeh et al. · 2021 · Critical Reviews in Oncology/Hematology
27. Current status and clinical application of patient-derived tumor organoid model in kidney and prostate cancers
    Eunjeong Seo, Minyong Kang · 2022 · BMB Reports
28. Modelling the Tumour Microenvironment, but What Exactly Do We Mean by “Model”?
    Constantino Carlos Reyes‐Aldasoro · 2023 · Cancers
29. Genome‐scale metabolic models applied for human health and biopharmaceutical engineering
    Feiran Li, Yu Chen, Johan Gustafsson, Hao Wang, Yi Wang, Chong Zhang, Xin‐Hui Xing · 2023 · Quantitative Biology
30. MicroRNA-34a-5p: A pivotal therapeutic target in gallbladder cancer
    Oda T, Koichiro Tsutsumi, Taisuke Obata, Eijiro Ueta, Tatsuya Kikuchi, Soichiro Ako, Yuki Fujii, Tatsuhiro Yamazaki, Daisuke Uchida, Kazuyuki Matsumoto et al. · 2024 · Molecular Therapy Oncology
31. Inverse design of three-dimensional multicellular biobots with target functions
    Hui-Kai Zhang, Bowen Xu, Zi-Yao Jia, Bo Li, Xi‐Qiao Feng · 2024 · Journal of the Mechanics and Physics of Solids
32. Emerging In Vitro and In Vivo Models: Hope for the Better Understanding of Cancer Progression and Treatment
    Rachana Yadav, Srushti Mahajan, Hoshiyar Singh, Neelesh Kumar Mehra, Jitender Madan, Nandkumar S. Doijad, Pankaj Kumar Singh, Santosh Kumar Guru · 2024 · Advanced Biology
33. Intracellular domain of epithelial cell adhesion molecule induces Wnt receptor transcription to promote colorectal cancer progression
    Sushree Shankar Panda, Chi‐Chiu Lee, Khamushavalli Geevimaan, Kai-Chi Chen, Shung‐Haur Yang, Chia‐Ning Shen, Wei‐Chun HuangFu, Han‐Chung Wu · 2024 · Journal of Biomedical Science
34. Recent advances in CRISPR-Cas systems for colorectal cancer research and therapeutics
    Saeideh Khorshid Sokhangouy, Farzaneh Lal Alizadeh, Malihe Lotfi, Samaneh Sharif, Atefeh Ashouri, Yasamin Yoosefi, Saeed Bozorg Qomi, Mohammad Reza Abbaszadegan · 2024 · Expert Review of Molecular Diagnostics
35. Organoids in Haematologic Research: Advances and Future Directions
    Liangzheng Chang, Lu Li, Yuling Han, Hui Cheng, Liuliu Yang · 2025 · Cell Proliferation
36. A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates In Vivo Tumor Phenotypes and Heterogeneity
    Michael J. Buckenmeyer, Elizabeth A. Brooks, Madison S. Taylor, Ireolu K. Orenuga, Liping Yang, Ronald J. Holewinski, Thomas Joshua Meyer, Melissa Galloux, Marcial Garmendia‐Cedillos, Thomas J. Pohida et al. · 2025 · Cancer Research
37. Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening
    Minkyu Shin, Joungpyo Lim, Seewoo Kim, Sangeun Lee, Wei Su, Jinho Yoon, Jeong‐Woo Choi · 2025 · Advanced Science
38. Harnessing induced pluripotent stem cells and organoids for disease modeling and precision medicine
    Lee, Chang-Jin, Nam, Yoojun, Rim, Yeri Alice, Ju, Ji Hyeon · 2026 · Stem Cell Research & Therapy
39. A tumour-derived organoid biobank maps cancer gene dependencies
    Carmen Herranz‐Ors, Shriram G. Bhosle, A. E. Beck, James G. R. Gilbert, Gabriele Picco, Jose Espejo Valle-Inclán, Francesc Muyas, S. Valentini, A. E. Andres, R. Ansari et al. · 2026 · Nature
40. Integration of Genomic Profiling and Organoid Development in Precision Oncology
    Hyunho Yoon, Sanghoon Lee · 2021 · International Journal of Molecular Sciences
41. Disease Modeling of Pituitary Adenoma Using Human Pluripotent Stem Cells
    Ryusaku Matsumoto, Hidetaka Suga, Hiroshi Arima, Takuya Yamamoto · 2022 · Cancers
42. Systems Biology
    Leszek Konieczny, Irena Roterman-Konieczna, Paweł Spólnik · 2023 · Springer eBooks
43. Fractional Dynamics and Recurrence Analysis in Cancer Model
    Enrique Chipicoski Gabrick, Matheus Rolim Sales, Elaheh Sayari, José Trobia, Ervin Kaminski Lenzi, Fernando S. Borges, José Danilo Szezech Junior, Kelly C. Iarosz, Ricardo Luiz Viana, Iberê Luiz Caldas et al. · 2023 · Brazilian Journal of Physics
44. Organoids and metastatic orthotopic mouse model for mismatch repair-deficient colorectal cancer
    Yurong Song, Travis D. Kerr, Chelsea Sanders, Lisheng Dai, Shaneen S. Baxter, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn et al. · 2023 · Frontiers in Oncology
45. Tissue Spatial Omics Dissects Organoid Biomimicry
    Nicholas Y. Zhang, Denis J. Ohlstrom, Sicheng Pang, Nivik Sanjay Bharadwaj, Aaron Qu, Hans E. Grossniklaus, Ahmet F. Coskun · 2023 · GEN Biotechnology
46. Bibliometrics analysis based on the Web of Science: Current trends and perspective of gastric organoid during 2010-2023
    Kailin Jiang, Yue-Bo Jia, Xuejiao Liu, Qingling Jia, Li-Kun Guo, Xiangxiang Wang, Keming Yang, Chen-Heng Wu, Bei-Bei Liang, Jianghong Ling · 2024 · World Journal of Gastroenterology
47. The reprotoxic adverse side effects of neurogenic and neuroprotective drugs: current use of human organoid modeling as a potential alternative to preclinical models
    Mariam Mahmoud Abady, Ji‐Seon Jeong, Ha‐Jeong Kwon, Abdullah M. Assiri, Jongki Cho, Islam M. Saadeldin · 2024 · Frontiers in Pharmacology
48. Pre-clinical models of small cell lung cancer and the validation of therapeutic targets
    Jane Sze Yin Sui, Petra Martin, Steven G. Gray · 2020 · Expert Opinion on Therapeutic Targets
49. Profiling of conditionally reprogrammed cell lines for in vitro chemotherapy response prediction of pancreatic cancer
    Hee Seung Lee, Eun‐Young Kim, Jin‐Young Lee, Seung Joon Park, Ho Kyoung Hwang, Chan Hee Park, Se-Young Jo, Chang Moo Kang, Seung‐Mo Hong, Huapyong Kang et al. · 2021 · EBioMedicine
50. COVID-19 Pandemic: Advances in Diagnosis, Treatment, Organoid Applications and Impacts on Cancer Patient Management
    Chenyang Ye, Lina Qi, Wang Ji, Shu Sen Zheng · 2021 · Frontiers in Medicine
51. High-resolution radioluminescence microscopy of FDG uptake in an engineered 3D tumor-stoma model
    Syamantak Khan, Sungwoo Kim, Yunzhi Yang, Guillem Pratx · 2021 · European Journal of Nuclear Medicine and Molecular Imaging
52. A live single-cell reporter assay links intratumor heterogeneity to metastatic proclivity in Ewing sarcoma
    Tugba Keskin, Beatrice Rucci, Sandrine Cornaz-Buros, Patricia Martin, Carlo Fusco, Liliane C. Broye, Katarina Vizar Cisarova, Elizabeth M. Perez, Igor Letovanec, Stefano La Rosa et al. · 2021 · Science Advances
53. Advances in preclinical evaluation of experimental antibody-drug conjugates
    Scott K. Lyons, Dennis Plenker, Lloyd C. Trotman · 2021 · Cancer Drug Resistance
54. Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis
    Sampath Kumar Katakam, Santosh Kumar Anand, Patricia Martin, Nicolò Riggi, Ivan Stamenkovic · 2022 · Life Science Alliance
55. 3D magnetic field guided sunflower-like nanocatalytic active swarm targeting patients-derived organoids
    Dong Liu, Ruirui Guo, Shuangshuang Mao, Yanjie Huang, Bin Wang, Zijian Wu, Xuanjie Xia, Jian Dong, Yu Xin, Ruiyang Xie et al. · 2022 · Nano Research
56. Assessment of stromal SCD-induced drug resistance of PDAC using 3D-printed zPDX model chips
    Chuntao Wu, Beiyuan Hu, Lei Wang, Xia Wu, Haitao Gu, Hanguang Dong, Jiuliang Yan, Zihao Qi, Qi Zhang, Huan Chen et al. · 2022 · iScience
57. Organoid models of breast cancer in precision medicine and translational research
    Vahid Niazi, Benyamin Parseh · 2024 · Molecular Biology Reports
58. Bridging the gap between tumor and disease: Innovating cancer and glioma models
    Stéfano M. Cirigliano, Howard Alan Fine · 2024 · The Journal of Experimental Medicine
59. The pros and cons of mechanical dissociation and enzymatic digestion in patient-derived organoid cultures for solid tumor
    Jing Ren, Mengli Liu, Mingjie Rong, Xuan Zhang, Gang Wang, Yihan Liu, Haijun Li, Shichao Duan · 2024 · Cell organoid (Print)
60. Current applications, future Perspectives and challenges of Organoid technology in oral cancer research
    Yunyi Wang, Xiang Ying Sun, Bingxu Lu, Danya Zhang, Yaping Yin, Shuguang Liu, Lei Chen, Zhaoqiang Zhang · 2025 · European Journal of Pharmacology
61. Hepatobiliary organoid research: the progress and applications
    Rui-Qi Zou, Yu-Shi Dai, Fei Liu, Siqi Yang, Hai‐Jie Hu, Fu‐Yu Li · 2025 · Frontiers in Pharmacology
62. Discovery of WEE1 Kinase Inhibitors with Potent Activity against Patient-Derived, Metastatic Colorectal Cancer Organoids
    Joel L. Syphers, Josephine A. Wright, Shen Liu, Yi Sing Gee, Fan Gao, Ramesh Mudududdla, Da Qing Che, Aeson Chang, Erica K. Sloan, Vignesh Narasimhan et al. · 2025 · Journal of Medicinal Chemistry
63. Endocrine cancer organoids in basic and translational medical research
    Dong Chen, Zhulan Chen, Huihui Yang, Lei Zhang, Chenchen Hu, Zhuo Yang, Peng Li, Xi Su, Xiaoling Liu, Wei Wei et al. · 2025 · Science China Life Sciences
64. Breast cancer metastasis: Is it a matter of OMICS and proper ex-vivo models?
    Mario Cioce, Andrea Sacconi, Sara Donzelli, Claudia Bonomo, Letizia Perracchio, Mariantonia Carosi, Stefano Maria Telera, Vito Michele Fazio, Claudio Botti, Sabrina Strano et al. · 2022 · Computational and Structural Biotechnology Journal
65. A multispectral 3D live organoid imaging platform to screen probes for fluorescence guided surgery
    Bernadette Jeremiasse, Ravian L. van Ineveld, Veerle Bok, Michiel Kleinnijenhuis, Sam de Blank, María Alieva, Hannah R. Johnson, Esmée J. van Vliet, Amber L. Zeeman, Lianne M. Wellens et al. · 2024 · EMBO Molecular Medicine
66. The application of organoids in colorectal diseases
    Yanxin Liu, Dongxu Wang, Yanhong Luan, Boqiang Tao, Qirong Li, Qiang Feng, Hengzong Zhou, Jianfeng Mu, Jinhai Yu · 2024 · Frontiers in Pharmacology
67. Mathematical Modeling of Tumor Growth in Preclinical Mouse Models with Applications in Biomarker Discovery and Drug Mechanism Studies
    Huajun Zhou, Binchen Mao, Sheng Jie Guo · 2024 · Cancer Research Communications
68. A Primary Cell and Organoid Platform for Evaluating Pharmacological Responses in Mammary Epithelial Cells
    Teneale A. Stewart, Felicity M. Davis · 2020 · ACS Pharmacology & Translational Science
69. Genome Engineering Evolves Brain Tumor Modeling
    Tomoyuki Koga, Clark C. Chen, Frank B. Furnari · 2020 · Neurologia medico-chirurgica
70. Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids
    Julia L. Steinmetz, Wojciech Senkowski, Johan Lengqvist, Jenny Rubin, Elena Ossipova, Stephanie Herman, Rolf L. Larsson, Per‐Johan Jakobsson, Mårten Fryknäs, Kim Kultima · 2020 · ACS Omega
71. Cancer Patient Tissueoid with Self‐Homing Nano‐Targeting of Metabolic Inhibitor
    Hyo‐Jin Yoon, Young Shin Chung, Yong Jae Lee, Seung Eun Yu, Sewoom Baek, Hye‐Seon Kim, Sang Wun Kim, Jung‐Yun Lee, Sunghoon Kim, Hak‐Joon Sung · 2021 · Advanced Science
72. Context Matters—Why We Need to Change From a One Size Fits all Approach to Made-to-Measure Therapies for Individual Patients With Pancreatic Cancer
    Sushmitha Sankarasubramanian, Ulrike Pfohl, Christian R. A. Regenbrecht, Christoph Reinhard, Lena Wedeken · 2021 · Frontiers in Cell and Developmental Biology
73. In‐depth analysis of the relationship between bovine intestinal organoids and enteroids based on morphology and transcriptome
    Juntao Zhang, Juanjuan Li, Penghui Yan, Laizeng He, Xuemei Zhang, Xiaolong Wang, Yake Shi, Lixin Deng, Zhiping Zhang, Baoyu Zhao · 2022 · Journal of Tissue Engineering and Regenerative Medicine
74. Single Cell RNA Sequencing: A New Frontier in Pancreatic Ductal Adenocarcinoma
    Maroun Bou Zerdan, Malek Shatila, Dhruv Sarwal, Youssef Bouferraa, Morgan Bou Zerdan, Sabine Allam, Merima Ramovic-Zobic, Stephen L. Graziano · 2022 · Cancers
75. Engineering Cancer Selective Virotherapies: Are the Pieces of the Puzzle Falling into Place?
    Emma A. Swift, Steven M. Pollard, Alan L. Parker · 2022 · Human Gene Therapy
76. Super-Long SERS Active Single Silver Nanowires for Molecular Imaging in 2D and 3D Cell Culture Models
    Xiao-Tong Pan, Xuanye Yang, Tian-Qi Mao, Kang Liu, Zaozao Chen, Lina Ji, Dechen Jiang, Kang Wang, Zhongze Gu, Xing‐Hua Xia · 2022 · Biosensors
77. Tumor Models and Drug Targeting In Vitro—Where Are We Today? Where Do We Go from Here?
    Marcus Krüger, Sascha Kopp · 2023 · Cancers
78. A gastric cancer patient-derived three-dimensional cell spheroid culture model.
    Hua Zhang, Yufen Qin, Mengting Jia, Lei Li, Wei Zhang, Lu Li, Zhixin Zhang, Yanrong Liu · 2023 · PubMed Central
79. Carcinogenesis: Mechanisms and Evaluation
    Mark James Hoenerhoff, Molly H. Boyle, Sheroy Minocherhomji, Arun R. Pandiri · 2021 · Elsevier eBooks
80. Fabrication of lumen-forming colorectal cancer organoids using a newly designed laminin-derived bioink
    Rosario Pérez-Pedroza, Fatimah Al-Jalih, Jiayi Xu, Manola Moretti, Giuseppina R. Briola, Charlotte A. E. Hauser · 2022 · International Journal of Bioprinting
81. New focuses of clinical and translational medicine in 2020
    Cheng Xin, Duojiao Wu, Yunfeng Cheng, Tiankui Qiao, Xiangdong Wang · 2020 · Clinical and Translational Medicine
82. ER stress and lipid imbalance drive embryonic cardiomyopathy in a human heart organoid model of pregestational diabetes
    Aleksandra S. Kostina, Yonatan R. Lewis‐Israeli, Mishref Abdelhamid, Mitchell A. Gabalski, Brett D. Volmert, Haley Lankerd, Amanda Huang, Aaron H. Wasserman, Todd A. Lydic, Christina Chan et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
83. Standard: Human intestinal cancer organoids
    Hanqing Lin, Yalong Wang, Chunyan Cheng, Yuxin Qian, Jie Hao, Zhen Zhang, Weiqi Sheng, Linhong Song, Chu‐Xia Deng, Bing Tian Zhao et al. · 2023 · Cell Regeneration
84. A single cell RNAseq benchmark experiment embedding “controlled” cancer heterogeneity
    Maddalena Arigoni, Maria Luisa Ratto, Federica Riccardo, Elisa Balmas, Lorenzo Calogero, Francesca Cordero, Marco Beccuti, Raffaele Calogero, Luca Alessandrì · 2024 · Scientific Data
85. Atherosclerotic three-layer nanomatrix vascular sheets for high-throughput therapeutic evaluation
    Jun Chen, Xixi Zhang, Robbie Cross, Yujin Ahn, Gillian N. Huskin, Will Evans, Patrick T.J. Hwang, Jeong‐a Kim, Brigitta C. Brott, Hanjoong Jo et al. · 2023 · Biomaterials
86. Preliminary study of utilizing a patient derived tumor spheroid model to augment precision therapy in metastatic brain tumors
    Chun-Jen Chang, Kai‐Wen Kan, Yu‐Yin Shih, Yu-Han Nan, Yu-Chung Juan, Chih-Hsiu Tu, Chen-Ting Yang, Wei-Lin Hsu, Der‐Yang Cho, Ming‐You Shie et al. · 2024 · Scientific Reports
87. Preclinical research models for endometrial cancer: development and selection of animal models
    Xue Yang, Wei Kang Shi, Bing Lun, M. I. Kan, Mengling Jia, Yuelin Wu, Yang Li · 2025 · Frontiers in Oncology
88. Differences in chemotherapeutic drug sensitivity before and after patient-derived tumor organoid construction
    Fang Shao, Xin Hua Huang, Zhihong Ma, Liqin Li, Chunjian Qi · 2025 · Toxicology and Applied Pharmacology
89. Macrophage-Membrane-Coated Enzyme-Driven Nanorobot for Tumor Organoids Penetration and Cancer Treatment
    Maoshu Zhu, Huijing Chen, Qunying Sheng, Ziwei Zhang, Solomon Wong, Fanwei Zeng, Qian Xu, Jianqian Fu, Zhongquan Qi, Jinlong Liang · 2025 · ACS Applied Nano Materials
90. Optimizing GBM organoid construction with hydrogel-based models: GelMA-HAMA scaffold supports GBM organoids with clonal growth for drug screening
    Min Zhou, Ke Yue, Jingjing Zhao, Shuhua Gong, Yutong Xie, Wenyu Wu, Zhen-zhou Li, Shuo Wu, Zhengliang Gao, Huan Wang et al. · 2025 · Cell Transplantation
91. Advancements and challenges in culturing patient-derived cancer cells for personalized therapeutics
    Yatian Fu, Bee Luan Khoo, Chwee Teck Lim · 2025 · Frontiers in Lab on a Chip Technologies
92. Organoid‐based novel technology for antitumor drug screening
    Yu-Cheng Su, Yuan Chen, Guanning Wei, Yihai Shi · 2025 · Open Research (University of Surrey)
93. Head and neck cancer organoids: a panoramic perspective from basic construction to clinical translation
    Ruoyu Meng, Lianpin Yu, Xiaomei Li, Na Ning, Haibin Hao, Xiaonan Zhang, Wei Song, Wei Song, Xinyu Li · 2025 · Stem Cell Research & Therapy
94. Organoid‐based two‐step drug screening for rapid identification of chemotherapy‐resistant oesophageal squamous cell carcinoma and alternative therapies
    Chenye Shao, Sheng Ju, Xin Tong, Kang Hu, Li Yu, Yi‐xian Zhu, Jian Yang, Chang Li, Yufeng Xie, Yuan‐Lu Cui et al. · 2025 · Clinical and Translational Medicine
95. Organoids, organ-on-a-chip, and microtumors: Biomimetic 3D tumor models advancing drug development and precision medicine
    Mengjiao Xia, Guohua Wu, Di Wu, Wenqi Hu, Hongbin Deng, Shuqi Wang · 2026 · Acta Pharmaceutica Sinica B
96. The utility of 3D models to study cholesterol in cancer: Insights and future perspectives
    Thea-Leonie du Plessis, Naaziyah Abdulla, Mandeep Kaur · 2023 · Frontiers in Oncology
97. Patient-derived melanoma models
    Franziska Karras, Manfred Kunz · 2024 · Pathology - Research and Practice
98. Acquired NF2 mutation confers resistance to TRK inhibition in an ex vivo LMNA :: NTRK1‐ rearranged soft‐tissue sarcoma cell model
    Yanjiang Chen, Sabrina Steiner, Catherine Hagedorn, Sarah Kollar, Alicia Pliego‐Mendieta, Martina Haberecker, Jan A. Plock, Christian Britschgi, Lara Planas‐Paz, Chantal Pauli · 2024 · The Journal of Pathology
99. Clinicopathological Factors as Predictors for Establishment of Patient Derived Head and Neck Squamous Cell Carcinoma Organoids
    W. W. B. de Kort, R. Millen, Else Driehuis, Lot A. Devriese, Robert J.J. van Es, Stefan M. Willems · 2024 · Head and Neck Pathology
100. Establishing a cryopreserved biobank of living tumor tissues for drug sensitivity testing
     Ping Chen, Jingbo Zhou, Xiangpeng Chu, Yangyang Feng, Qibing Zeng, Josh-Haipeng Lei, Ka-Pou Wong, Tai-Ip Chan, Chon-Wa Lam, Wenli Zhu et al. · 2024 · Bioactive Materials