The DOI matches its Crossref record; 199 of the 199 references it cites were found in a registry or an index.
Axonal transport: Driving synaptic function
Open accessAbstract
From trafficking to maintenance: Neurons are remarkably polarized in that proteins made in the cytosol often need to travel many tens or hundreds of cell body lengths along axons to their sites of action in the synapse. Axonal transport of these components is driven by molecular motors along axonal microtubules. Guedes-Dias and Holzbaur review the cell biology of axonal transport and highlight the roles this fundamental process plays in organismal health. Science , this issue p. eaaw9997
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“Further, given that the centrum semiovale had the second highest estimated effect size (Cohen’s d of 0.51) and that we saw an effect of intervention duration for the centrum semiovale, we cannot exclude that the SSRI intervention could have an effect on the specific binding in the white matter, e.g. due to increased axonal transport of newly synthesized synaptic vesicle precursors [56].”
From Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial (2023) · cites this paper as [56]
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Self-citationQuantitative ultrastructural analysis of hippocampal excitatory synapses
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Metadata
- Authors
- Guedes-Dias, P., & Holzbaur, E. L. F.
- Affiliations
- Technical University of Munich (DE)
- University of Pennsylvania (US)
- Corresponding author
- Holzbaur, Erika L. F.
- Venue
- Science
- Published
- 2019-10-11
- Volume
- 366
- Issue
- 6462
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC6996143
- OpenAlex
- W2979904465
- Cited by
- 355
- References
- 199
- Citations by year
- 2026: 43 · 2025: 65 · 2024: 61 · 2023: 43 · 2022: 63 · 2021: 44 · 2020: 31 · 2019: 3
- FWCI
- 4.68
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (R35 GM126950)
- Alexander von Humboldt-Stiftung
- Deutsche Forschungsgemeinschaft (EXC 2145 SyNergy)
- Elite Network Bavaria
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Keywords
- axonal transport, kinesin motors, dynein motor, microtubules, vesicle trafficking, presynaptic terminals, synaptic function, synaptic transmission, growth factor transport, protein aggregation, learning and memory
- MeSH terms
- Animals, Axonal Transport, Humans, Microtubules, Protein Processing, Post-Translational, Synapses, Tubulin, Protein Isoforms, Mice
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