An orally available non-nucleotide STING agonist with antitumor activity

Pan, Bo-Sheng, Perera, Samanthi A., Piesvaux, Jennifer A., Presland, Jeremy P., Schroeder, Gottfried K., Cumming, Jared N., Trotter, B. Wesley, Altman, Michael D. +33 more·2020·Science

Cited by (709)

Items 701–709 of 709

  1. BindingDB Entry 50023247: Discovery of Potent STING Inhibitors Bearing a Difluorobenzodioxol Structural Motif as Potent Anti-Inflammatory Agents.
    BindingDB · 2026 · UC San Diego
  2. BindingDB Entry 50017730: Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor.
    BindingDB · 2023 · UC San Diego
  3. BindingDB Entry 50013465: Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists.
    BindingDB · 2022 · UC San Diego
  4. BindingDB Entry 50023611: Design, Synthesis, and Biological Evaluation of Selective STING Synergists That Enhance cGAMP-STING Pathway Activation without Inherent Agonist Activity.
    BindingDB · 2026 · UC San Diego
  5. BindingDB Entry 50015958: Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists.
    BindingDB · 2023 · UC San Diego
  6. BindingDB Entry 50023773: Design of an Oral STING Agonist through Intramolecular Hydrogen Bond Ring Mimicking to Achieve Complete Tumor Regression.
    BindingDB · 2026 · UC San Diego
  7. cGAS–STING signaling in immunity and disease: molecular mechanisms, context-dependent functions, and therapeutic modulation
    Jiaxin Zhao, Cheng‐long Zhu, Yue Shu, Biaoyu Guo, Wenyun Xu · 2026 · Medicine Plus
  8. Development of 18F-Labeled Cyclic Peptides for PET Imaging of STING Expression
    Jianyang Fang, Jingru Zhang, Lingxin Meng, Huan Lu, 洪开其, Ziying Zhou, Yesen Li, Xianzhong Zhang, Zhide Guo · 2026 · Journal of Pharmaceutical Analysis
  9. Discovery of tricyclic analogues as novel stimulator of interferon genes (STING) receptor agonists via structural optimization of a repurposed drug
    Nan-Nan Chen, Qiangsheng Zhu, Wenjing Bian, Lin-Lin Li, Chen Tong, Guo-Feng Xin, Zi-Wen Feng, Shi-Duo Zhang, De-Chang Li, Chen-Yu Wang et al. · 2026 · Chinese Chemical Letters