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Julich-Brain: A 3D probabilistic atlas of the human brain’s cytoarchitecture

Amunts, Katrin, Mohlberg, Hartmut, Bludau, Sebastian, Zilles, Karl·2020·Science

Abstract

A present-day atlas of the human brain: Defining brain regions and demarking their spatial extent are important goals in neuroscience. A modern map of the brain's cellular structure, a cytoarchitectonic atlas, should provide maps of areas in three dimensions, integrate recent knowledge about brain parcellation, consider variations between individual brains, rely on reproducible workflows, and provide web-based links to other resources and databases. Amunts et al. created such an atlas based on serial histological sections of brain. They developed a computational framework and refined the current boundaries of the human brain based on cytoarchitectural patterns. This technique can easily be transferred to build brain atlases for other species or a spatial framework for other organs, other modalities, or multimodal maps for regions of interest at higher spatial scales. This research makes similar future attempts simultaneously reproducible and flexible. Science , this issue p. 988

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Metadata

Authors
Amunts, K., Mohlberg, H., Bludau, S., & Zilles, K.
Affiliations
Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Venue
Science
Published
2020-08-21
Volume
369
Issue
6506
Pages
988-992
ISSN
  • 0036-8075
  • 1095-9203
Cited by
644
References
7
Language
en

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CoChat. (2026). Citation check: Julich-Brain: A 3D probabilistic atlas of the human brain’s cytoarchitecture. https://app.cochat.ai/papers/10.1126/science.abb4588
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Amunts, K., Mohlberg, H., Bludau, S., & Zilles, K. (2020). Julich-Brain: A 3D probabilistic atlas of the human brain’s cytoarchitecture. Science. https://doi.org/10.1126/science.abb4588