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Julich-Brain: A 3D probabilistic atlas of the human brain’s cytoarchitecture
Abstract
A present-day atlas of the human brain: Defining brain regions and demarking their spatial extent are important goals in neuroscience. A modern map of the brain's cellular structure, a cytoarchitectonic atlas, should provide maps of areas in three dimensions, integrate recent knowledge about brain parcellation, consider variations between individual brains, rely on reproducible workflows, and provide web-based links to other resources and databases. Amunts et al. created such an atlas based on serial histological sections of brain. They developed a computational framework and refined the current boundaries of the human brain based on cytoarchitectural patterns. This technique can easily be transferred to build brain atlases for other species or a spatial framework for other organs, other modalities, or multimodal maps for regions of interest at higher spatial scales. This research makes similar future attempts simultaneously reproducible and flexible. Science , this issue p. 988
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“While atlases describing inter-subject variability of human cortex exist for the micro- and macroscopic scales (61), a lack of human datasets at the nanometer scale means that inter-subject variability of human cortical microcircuits is currently not known.”
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A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution
Shapson-Coe, A., Januszewski, M., Berger, D. R., Pope, A., Wu, Y., Blakely, T., Schalek, R. L., Li, P. H., Wang, S., Maitin-Shepard, J., et al. (2024) · Science · doi:10.1126/science.adk4858 · Cited by 361
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Transcriptomic cytoarchitecture reveals principles of human neocortex organization
Jorstad, N. L., Close, J., Johansen, N., Yanny, A. M., Barkan, E. R., Travaglini, K. J., Bertagnolli, D., Campos, J., Casper, T., Crichton, K., et al. (2023) · Science · doi:10.1126/science.adf6812 · Cited by 209
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The macaque ventral intraparietal area has expanded into three homologue human parietal areas
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Reduced age-related gray matter loss in the subgenual cingulate cortex in long-term meditators.
Kurth, F., Zsadanyi, S. E., & Luders, E. (2021) · Brain Imaging and Behavior · doi:10.1007/s11682-021-00578-6 · Cited by 11
Synthesizing Multi-Modal Imaging for Enhanced Brain Mapping in Neurology: a State-of-the-art Review
Kumar, P., Mohammad, T. K., Pramod Kumar, A., Kassym, R., A. S., T., & Akmaral, T. (2024) · 2024 5th International Conference on Communications, Information, Electronic and Energy Systems (CIEES) · doi:10.1109/ciees62939.2024.10811448 · Cited by 4
Metadata
- Authors
- Amunts, K., Mohlberg, H., Bludau, S., & Zilles, K.
- Affiliations
- Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
- Venue
- Science
- Published
- 2020-08-21
- Volume
- 369
- Issue
- 6506
- Pages
- 988-992
- ISSN
- 0036-8075
- 1095-9203
- Cited by
- 644
- References
- 7
- Language
- en
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