Human NLRP1 is a sensor for double-stranded RNA

The Inflammasome

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Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Sun, L., Wu, J., Du, F., Chen, X., & Chen, Z. J. (2013) · Science · doi:10.1126/science.1232458 · Cited by 4,996

Inflammasomes: mechanism of assembly, regulation and signalling

Broz, P., & Dixit, V. M. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.58 · Cited by 3,500

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

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The gasdermins, a protein family executing cell death and inflammation

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Kanneganti, T., Özören, N., Body–Malapel, M., Amer, A. O., Park, J., Franchi, L., Whitfield, J. R., Barchet, W., Colonna, M., Vandenabeele, P., et al. (2006) · Nature · doi:10.1038/nature04517 · Cited by 1,149

Human Keratinocytes That Express hTERT and Also Bypass a p16 INK4a -Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics

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MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Coll, R. C., Hill, J. R., Day, C. J., Zamoshnikova, A., Boucher, D., Massey, N. L., Chitty, J. L., Fraser, J. A., Jennings, M. P., Robertson, A. A. B., et al. (2019) · Nature Chemical Biology · doi:10.1038/s41589-019-0277-7 · Cited by 1,041

Structural mechanism of cytosolic DNA sensing by cGAS

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Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

Schlee, M., Roth, A. H. F. J., Hornung, V., Hagmann, C. A., Wimmenauer, V., Barchet, W., Coch, C., Janke, M., Mihailovic, A., Wardle, G. S., et al. (2009) · Immunity · doi:10.1016/j.immuni.2009.05.008 · Cited by 814

Recent insights into innate immune nucleic acid sensing during viral infection

Guy, C., & Bowie, A. (2022) · Current Opinion in Immunology · doi:10.1016/j.coi.2022.102250 · Cited by 30

Inflammasome activation by viral infection: mechanisms of activation and regulation

Shi, W., Jin, M., Chen, H., Wu, Z., Yuan, L., Liang, S., Wang, X., Memon, F. U., Eldemery, F., Si, H., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1247377 · Cited by 34

Implication of the LRR Domain in the Regulation and Activation of the NLRP3 Inflammasome

Cescato, M., Zhu, Y. Y. J., Corre, L. L., Py, B. F., Georgin‐Lavialle, S., & Rodero, M. P. (2024) · Cells · doi:10.3390/cells13161365 · Cited by 32

Chemical Modulation of Gasdermin-Mediated Pyroptosis and Therapeutic Potential

Ryder, C. B., Kondolf, H. C., O'Keefe, M. E., Zhou, B., & Abbott, D. W. (2021) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.167183 · Cited by 28

Nod-Like Receptors in Host Defence and Disease at the Epidermal Barrier

Danis, J., & Mellett, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094677 · Cited by 28

Inflammasomes in T cells

Linder, A., & Hornung, V. (2021) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.167275 · Cited by 26

Inflammation and Heart Failure: Searching for the Enemy—Reaching the Entelechy

PARASKEVAIDIS, I. A., Farmakis, D. T., Papingiotis, G., & Tsougos, E. (2023) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd10010019 · Cited by 27

Small molecule modulators of immune pattern recognition receptors

Tsukidate, T., Hespen, C. W., & Hang, H. C. (2023) · RSC Chemical Biology · doi:10.1039/d3cb00096f · Cited by 26

Viral sensing by epithelial cells involves PKR- and caspase-3-dependent generation of gasdermin E pores

Guy, C., Baran, M., Ribó-Molina, P., van den Hoogen, B. G., & Bowie, A. (2023) · iScience · doi:10.1016/j.isci.2023.107698 · Cited by 26

The Role of Inflammasomes in Glomerulonephritis

Antón-Pàmpols, P., Diaz-Requena, C., Martínez-Valenzuela, L., Gómez-Preciado, F., Fulladosa, X., Vidal‐Alabró, A., Torrás, J., Lloberas, N., & Draibe, J. B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084208 · Cited by 26

Pyroptosis in glioma: Current management and future application

Guo, Z., Su, Z., Wei, Y., Zhang, X., & Hong, X. (2023) · Immunological Reviews · doi:10.1111/imr.13294 · Cited by 25

Inflammasomes: a rising star on the horizon of COVID-19 pathophysiology

Wang, M., Yu, F., Chang, W., Zhang, Y., Zhang, L., & Li, P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1185233 · Cited by 25

The gasdermins: a pore-forming protein family expressed in the epidermis

Slaufova, M., Karakaya, T., Filippo, M. D., Hennig, P., & Beer, H. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1254150 · Cited by 28

Role of inflammasomes in acute respiratory distress syndrome

Flower, L., Vozza, E. G., Bryant, C. E., & Summers, C. (2025) · Thorax · doi:10.1136/thorax-2024-222596 · Cited by 26

Tripping the wire: sensing of viral protease activity by CARD8 and NLRP1 inflammasomes

Castro, L. K., & Daugherty, M. D. (2023) · Current Opinion in Immunology · doi:10.1016/j.coi.2023.102354 · Cited by 23

NLRP1 inflammasome promotes senescence and senescence-associated secretory phenotype

Muela‐Zarzuela, I., Suarez-Rivero, J. M., Gallardo-Orihuela, A., Wang, C., Izawa, K., de Gregorio-Procopio, M., Couillin, I., Ryffel, B., Kitaura, J., Sanz, A., et al. (2024) · Inflammation Research · doi:10.1007/s00011-024-01892-7 · Cited by 28

RNA recognition in toll-like receptor signaling

Shimizu, T. (2024) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2024.102913 · Cited by 22

PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

McKee, C. M., Fischer, F. A., Bezbradica, J. S., & Coll, R. C. (2021) · Biochemical Society Transactions · doi:10.1042/bst20200987 · Cited by 23

Aberrant inflammasome activation as a driving force of human autoimmune skin disease

Fetter, T., de Graaf, D. M., Claus, I., & Wenzel, J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1190388 · Cited by 25

Targeting Inflammasome Activation in Viral Infection: A Therapeutic Solution?

Deng, C.-H., Li, T., Zhang, W., Zhao, Q., & Wang, Y. (2023) · Viruses · doi:10.3390/v15071451 · Cited by 23

Effector-triggered immunity in mammalian antiviral defense

Orzalli, M. H., & Parameswaran, P. (2022) · Trends in Immunology · doi:10.1016/j.it.2022.10.004 · Cited by 19

Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans

Hansen, T. J., Fong, S., Day, J. K., Capra, J. A., & Hodges, E. C. (2024) · Cell Genomics · doi:10.1016/j.xgen.2024.100536 · Cited by 20

A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 inflammasome

Parameswaran, P., Payne, L., Powers, J., Rashighi, M., & Orzalli, M. H. (2024) · The Journal of Experimental Medicine · doi:10.1084/jem.20231518 · Cited by 19

Beyond Inhibition: A Novel Strategy of Targeting HIV-1 Protease to Eliminate Viral Reservoirs

Kim, J. G., & Shan, L. (2022) · Viruses · doi:10.3390/v14061179 · Cited by 22

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

Cohen, H., Baram, N., Fridman, C. M., Edry‐Botzer, L., Salomon, D., & Gerlic, M. (2022) · eLife · doi:10.7554/elife.82766 · Cited by 19

ZAKα/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome

Rodríguez‐Ruiz, L., Lozano‐Gil, J. M., Naranjo, E. S., Martínez‐Balsalobre, E., Martínez‐López, A., Lachaud, C., Blanquer, M., Phung, T. K., García‐Moreno, D., Cayuela, M. L., et al. (2023) · EMBO Molecular Medicine · doi:10.15252/emmm.202318142 · Cited by 19

Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes

Hasegawa, T., Noguchi, S., Nakashima, M., Miyai, M., Goto, M., Matsumoto, Y. M., Torii, S., Honda, S., & Shimizu, S. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107173 · Cited by 18

Great balls of fire: activation and signalling of inflammatory caspases

Bateman, G., Hill, B., Knight, R., & Boucher, D. (2021) · Biochemical Society Transactions · doi:10.1042/bst20200986 · Cited by 21

Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome

Kroken, A. R., Klein, K. A., Mitchell, P. S., Nieto, V., Jedel, E., Evans, D. J., & Fleiszig, S. M. J. (2023) · mSphere · doi:10.1128/msphere.00351-23 · Cited by 18

Influenza, SARS-CoV-2, and Their Impact on Chronic Lung Diseases and Fibrosis

Soni, S., Antonescu, L., Ro, K., Horowitz, J. C., Mebratu, Y. A., & Nho, R. S. (2024) · American Journal Of Pathology · doi:10.1016/j.ajpath.2024.06.004 · Cited by 19

Abortive HIV‐1 RNA induces pro‐IL‐1β maturation via protein kinase PKR and inflammasome activation in humans

Stunnenberg, M., van Hamme, J. L., Trimp, M., Gringhuis, S. I., & Geijtenbeek, T. B. H. (2021) · European Journal of Immunology · doi:10.1002/eji.202149275 · Cited by 18

SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity

Hou, G., Beatty, W. L., Ren, L., Ooi, Y. S., Son, J., Zhu, Y., Sheng, Q., Huang, W., Li, D., Liu, C., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59090-w · Cited by 16

Metabolic regulators of enigmatic inflammasomes in autoimmune diseases and crosstalk with innate immune receptors

Jimenez‐Duran, G., & Triantafilou, M. (2021) · Immunology · doi:10.1111/imm.13326 · Cited by 17

SARS-CoV-2 Spike-Mediated Entry and Its Regulation by Host Innate Immunity

Yu, S., Hu, H., Ai, Q., Bai, R., Ma, K., Zhou, M., & Wang, S. (2023) · Viruses · doi:10.3390/v15030639 · Cited by 20

Vitamin B12 attenuates leukocyte inflammatory signature in COVID-19 via methyl-dependent changes in epigenetic markings

Cassiano, L. M. G., Cavalcante‐Silva, V., Oliveira, M. D. S., Prado, B. V. O., Cardoso, C. G., Salim, A. C. M., Franco, G. R., D’Almeida, V., Francisco, S. C., & Coimbra, R. S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1048790 · Cited by 17

Phenome-wide and expression quantitative trait locus associations of coronavirus disease 2019 genetic risk loci

Moon, C. Y., Schilder, B. M., Raj, T., & Huang, K. (2021) · iScience · doi:10.1016/j.isci.2021.102550 · Cited by 16

Pathway of Cell Death and Its Role in Virus Infection

Chen, X., Zhang, W., Yi, W., Liu, Y., Bi, X., Lin, Y., Deng, W., Dong, J., Li, M., & Xie, Y. (2022) · Viral Immunology · doi:10.1089/vim.2022.0010 · Cited by 16

Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox inflammasome activation

Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., Vallese, A., Cervellati, F., & Valacchi, G. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102440 · Cited by 16

Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing

Singh, R., Wu, Y., Herrero del Valle, A., Leigh, K. E., Mong, S., Cheng, M. T. K., Ferguson, B. J., & Modis, Y. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.105711 · Cited by 16

Inflammasomes as the molecular hub of cardiovascular-metabolic-immune comorbidity networks

Qian, X., Sun, J. M., Li, F., Li, X., Hu, X., Dong, N., & Li, G. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1690443 · Cited by 18

Inflammasome and gasdermin signaling in neutrophils

Yow, S. J., Yeap, H. W., & Chen, K. W. (2022) · Molecular Microbiology · doi:10.1111/mmi.14891 · Cited by 17

Posttranslational Regulation of Inflammasomes, Its Potential as Biomarkers and in the Identification of Novel Drugs Targets

Nanda, S. K., Vollmer, S., & Pérez‐Oliva, A. B. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.887533 · Cited by 15

DPP9 restrains NLRP1 activation

Bauernfried, S., & Hornung, V. (2021) · Nature Structural & Molecular Biology · doi:10.1038/s41594-021-00580-y · Cited by 15

NLRP1 under pressure: An overview of the NLRP1 inflammasome as a sensor of cellular stress

Yap, J. K. Y., Duszyc, K., & Schroder, K. (2025) · Molecular Cell · doi:10.1016/j.molcel.2025.09.018 · Cited by 15

High p62 expression suppresses the NLRP1 inflammasome and increases stress resistance in cutaneous SCC cells

Hennig, P., Filippo, M. D., Bilfeld, G., Mellett, M., & Beer, H. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05530-0 · Cited by 14

Ferroptosis and pyroptosis: Mediating mechanisms of the cGAS/STING pathway and therapeutic strategies in heart failure

Zhang, Z., Yang, Z., Wang, S., Wang, X., & Mao, J. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102932 · Cited by 13

Inflammasomes during SARS-CoV-2 infection and development of their corresponding inhibitors

Diarimalala, R. O., Wei, Y., Hu, D., & Hu, K. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1218039 · Cited by 12

Advances in the mechanism of inflammasomes activation in herpes virus infection

Chen, H., Jian, Z., Xu, T. W., Xu, L., Deng, L., Shao, L., Zhang, L., He, L. Q., Li, Y., & Zhu, L. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1346878 · Cited by 13

CARD8: A Novel Inflammasome Sensor with Well-Known Anti-Inflammatory and Anti-Apoptotic Activity

Karakaya, T., Slaufova, M., Filippo, M. D., Hennig, P., Kündig, T. M., & Beer, H. (2024) · Cells · doi:10.3390/cells13121032 · Cited by 14

IL-18 biology in severe asthma

Thawanaphong, S., Nair, A., Volfson, E., Nair, P. K., & Mukherjee, M. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1486780 · Cited by 13

Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation

Gorse, L., Plessis, L., Wearne, S., Paradis, M., Pinilla, M., Chua, R., Lim, S. S., Pelluz, E., Toh, G. A., Mazars, R., et al. (2025) · EMBO Molecular Medicine · doi:10.1038/s44321-025-00197-4 · Cited by 17

The noncanonical inflammasome in health and disease

Cahoon, J. G., Yang, D., & Wang, P. (2022) · Infectious Medicine · doi:10.1016/j.imj.2022.09.001 · Cited by 12

Inflammasomes in epithelial innate immunity: front line warriors

Robinson, K. S., & Boucher, D. (2024) · FEBS Letters · doi:10.1002/1873-3468.14848 · Cited by 12

Strategies of bacterial detection by inflammasomes

Jastrab, J. B., & Kagan, J. C. (2024) · Cell chemical biology · doi:10.1016/j.chembiol.2024.03.009 · Cited by 14

Innate Immunity Never “NODs” Off: NLRs Regulate the Host Anti‐Viral Immune Response

Woolls, M. K., Mott, M., Poole, C. S., Gregory, J. A., Ivester, H. M., & Allen, I. C. (2025) · Immunological Reviews · doi:10.1111/imr.13429 · Cited by 13

Activation of the NLRP1 inflammasome and its ligand recognition in the antibacterial immune response of common carp (Cyprinus carpio)

Zhao, H., Wang, H., Liu, R., Liang, Y., Li, K., Shan, S., An, L., Yang, G., & Li, H. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.05.019 · Cited by 12

Sensing of viral RNA in plants via a DICER-LIKE RibonucleasePreprint

Nielsen, C. P. S., Han, L., Arribas‐Hernández, L., Karelina, D., Petersen, M., & Brodersen, P. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.10.523395 · Cited by 12

Targeting the NLRP3 Inflammasome-Gasdermin D Axis to Combat Cardiovascular Diseases

Choi, J. S. Y., Pervin, M., Vince, J. E., Sharma, A., & de Haan, J. B. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2025.09.006 · Cited by 15

Unraveling the Role of the NLRP3 Inflammasome in Lymphoma: Implications in Pathogenesis and Therapeutic Strategies

Stergiou, I. Ε., Tsironis, C., Papadakos, S. P., Tsitsilonis, O., Dimopoulos, M. A., & Theocharis, S. E. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042369 · Cited by 11

Recent Progress in Innate Immune Responses to Enterovirus A71 and Viral Evasion Strategies

Wei, J., Lv, L., Wang, T., Gu, W., Luo, Y., & Feng, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115688 · Cited by 11

Inflammasomes and Type 1 Diabetes

Pearson, J. A., Wong, F. S., & Li, W. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.686956 · Cited by 11

Herpesviruses and Inflammasomes: One Sensor Does Not Fit All

Ayush Kumar, A., Stavrakis, G., & Karaba, A. H. (2022) · mBio · doi:10.1128/mbio.01737-21 · Cited by 11

Engineered mRNAs With Stable Structures Minimize Double-stranded RNA Formation and Increase Protein Expression

Qin, Q., Yan, H., Gao, W., Cao, R., Liu, G., Zhang, X., Wang, N., Zuo, W., Yuan, L., Gao, P., et al. (2024) · Journal of Molecular Biology · doi:10.1016/j.jmb.2024.168822 · Cited by 11

Roles of RNA Sensors in Host Innate Response to Influenza Virus and Coronavirus Infections

Li, W., Wang, H., & Zheng, S. J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158285 · Cited by 10

Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain

Moecking, J., Laohamonthonkul, P., Meşe, K., Hagelueken, G., Steiner, A., Harapas, C. R., Sandow, J. J., Graves, J. D., Masters, S. L., & Geyer, M. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102645 · Cited by 10

The regulation of self-tolerance and the role of inflammasome molecules

Qi, K., Greenawalt, A. N., Manukonda, V., Ji, X., & Tisch, R. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1154552 · Cited by 11

Canonical Inflammasomes

Leal, V. N. C., & Pontillo, A. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3350-2_1 · Cited by 10

Supramolecular organizing centers at the interface of inflammation and neurodegeneration

Sušjan, P., Ramuta, T. Ž., Boršić, E., Orehek, S., & Hafner‐Bratkovič, I. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.940969 · Cited by 11

Genetic variants determine intrafamilial variability of SARS-CoV-2 clinical outcomes in 19 Italian families

Azzarà, A., Cassano, I., Paccagnella, E., Tirindelli, M. C., Nobile, C., Schittone, V., Lintas, C., Sacco, R., & Gurrieri, F. (2022) · PLoS ONE · doi:10.1371/journal.pone.0275988 · Cited by 10

Collab or Cancel? Bacterial Influencers of Inflammasome Signaling

Herrmann, B. I., Grayczyk, J. P., & Brodsky, I. E. (2023) · Annual Review of Microbiology · doi:10.1146/annurev-micro-032521-024017 · Cited by 9

Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells

Jalloh, S., Hughes, I. A., Akiyama, H., Gojanovich, A. D., Quiñones-Molina, A. A., Yang, M., Henderson, A. J., Mostoslavsky, G., & Gummuluru, S. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003320 · Cited by 9

Activation and manipulation of inflammasomes and pyroptosis during bacterial infections

Bernard, E. M., & Brož, P. (2022) · Biochemical Journal · doi:10.1042/bcj20220051 · Cited by 10

Respiratory viruses and the inflammasome: The double-edged sword of inflammation

Waldstein, K. A., & Varga, S. M. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1011014 · Cited by 10

Stratification of COVID-19 patients based on quantitative immune-related gene expression in whole blood

Persson, J., Andersson, B., van Veen, S., Haks, M. C., Obudulu, O., Torkzadeh, S., Ottenhoff, T. H. M., Kanberg, N., Gisslén, M., Andersson, L., et al. (2022) · Molecular Immunology · doi:10.1016/j.molimm.2022.03.004 · Cited by 9

Activation of the NLRP1B inflammasome by caspase-8

Meade, J. J., Stuart, S. E., Neiman-Zenevich, J., Krustev, C., Girardin, S. E., & Mogridge, J. (2024) · Communications Biology · doi:10.1038/s42003-024-06882-3 · Cited by 8

Chicken GSDME, a major pore-forming molecule responsible for RNA virus-induced pyroptosis in chicken

Chen, Z., Chang, H., Zhang, S., Gao, H., Gao, L., Cao, H., Li, X., Wang, Y., & Zheng, S. J. (2024) · Journal of Virology · doi:10.1128/jvi.01588-24 · Cited by 8

Inflammasomes: potential therapeutic targets in hematopoietic stem cell transplantation

Luo, J., Zhou, Y., Wang, M., Zhang, J. L., & Jiang, E. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01974-3 · Cited by 9

Endogenous double-stranded RNA: Bridging immune activation and cancer therapeutics

Liu, X., Che, L., & Weng, H. (2025) · Cell investigation. · doi:10.1016/j.clnves.2025.100018 · Cited by 10

O-GlcNAc transferase plays dual antiviral roles by integrating innate immunity and lipid metabolism

Dong, H., Liang, C., Zhang, J., Wu, W., Kumar, N., Liu, Z., Sun, Y., Liao, Z., Cheng, X., Yu, Y., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63085-y · Cited by 9

Host–Viral Interactions in the Pathogenesis of Ulcerative Colitis

Bruland, T., Østvik, A. E., Sandvik, A. K., & Hansen, M. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910851 · Cited by 8

Activation of the NLRP1 Inflammasome and Its Role in Transmissible Gastroenteritis Coronavirus Infection

He, H., Wang, W., Li, L., Zhang, X., Shi, H., Chen, J., Shi, D., Xue, M., & Feng, L. (2023) · Journal of Virology · doi:10.1128/jvi.00589-23 · Cited by 8

Can NLRP3 inhibitors improve on dexamethasone for the treatment of COVID-19?

Hooftman, A., & O'Neill, L. A. J. (2021) · Current Research in Pharmacology and Drug Discovery · doi:10.1016/j.crphar.2021.100048 · Cited by 8

Structural mechanisms of inflammasome regulation revealed by cryo-EM studies

Cao, J., Nash, G., & Zhang, L. (2022) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2022.102390 · Cited by 8

NLRP1 in Cutaneous SCCs: An Example of the Complex Roles of Inflammasomes in Cancer Development

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DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection

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