The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Signaling inflammation across the gut-brain axis
Abstract
The brain and gastrointestinal tract are critical sensory organs responsible for detecting, relaying, integrating, and responding to signals derived from the internal and external environment. At the interface of this sensory function, immune cells in the intestines and brain consistently survey environmental factors, eliciting responses that inform on the physiological state of the body. Recent research reveals that cross-talk along the gut-brain axis regulates inflammatory nociception, inflammatory responses, and immune homeostasis. Here, we discuss molecular and cellular mechanisms involved in the signaling of inflammation across the gut-brain axis. We further highlight interactions between the gut and the brain in inflammation-associated diseases.
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Self-citationNicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
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Cited by
Facchin, S., Bertin, L., Bonazzi, E., Lorenzon, G., De Barba, C., Barberio, B., Zingone, F., Maniero, D., Scarpa, M., Ruffolo, C., et al. (2024) · Life · doi:10.3390/life14050559 · Cited by 380
The gut microbiome modulates the transformation of microglial subtypes
Huang, Y., Wu, J., Zhang, H., Li, Y., Wen, L., Tan, X., Cheng, K., Liu, Y., Pu, J., Liu, L., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02017-y · Cited by 111
Zhao, Q., Chen, J., Wu, M., Yin, X., Jiang, Q., Gao, H., & Zheng, H. (2023) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2023.110638 · Cited by 49
Gut-brain axis in the pathogenesis of sepsis-associated encephalopathy
Wang, X., Wen, X., Yuan, S., & Zhang, J. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106499 · Cited by 47
Copper neurotoxicity: Induction of cognitive dysfunction: A review
Feng, D., Zhao, Y., Li, W., Li, X., Wan, J., & Wang, F. (2023) · Medicine · doi:10.1097/md.0000000000036375 · Cited by 38
Metadata
- Authors
- Agirman, G., Yu, K. B., & Hsiao, E. Y.
- Venue
- Science
- Published
- 2021-11-26
- Volume
- 374
- Issue
- 6571
- Pages
- 1087-1092
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W3216805703
- Cited by
- 832
- References
- 65
- FWCI
- 76.16
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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