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Fluoride exposure alters Ca 2+ signaling and mitochondrial function in enamel cells

Aulestia, Francisco J., Groeling, Johnny, Bomfim, Guilherme H. S., Costiniti, Veronica, Manikandan, Vinu, Chaloemtoem, Ariya, Concepcion, Axel R., Li, Yi, Wagner, Larry E., Idaghdour, Youssef, Yule, David I., Lacruz, Rodrigo S.·2020·Science Signaling
DOI 10.1126/scisignal.aay0086PMC PMC7173621
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Abstract

The mechanisms by which excessive fluoride causes defects in tooth enamel mineralization are revealed.

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Metadata

Authors
Aulestia, F. J., Groeling, J., Bomfim, G. H. S., Costiniti, V., Manikandan, V., Chaloemtoem, A., Concepcion, A. R., Li, Y., Wagner, L. E., Idaghdour, Y., Yule, D. I., & Lacruz, R. S.
Affiliations
  • Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY 10010, USA.
  • Biology Program, Division of Science and Mathematics, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
  • Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.
  • Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14526, USA.
ORCID
Venue
Science Signaling
Publisher
American Association for the Advancement of Science (AAAS)
Published
2020-02-18
Volume
13
Issue
619
ISSN
  • 1945-0877
  • 1937-9145
DOI
10.1126/scisignal.aay0086
PMC
PMC7173621
Cited by
61
References
1
Language
en
Funders
  • National Institutes of Dental and Craniofacial Research (R01DE025639 and R01DE027679)
  • National Institutes for Dental and Craniofacial Research (R01DE014756)

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CoChat. (2026). Citation check: Fluoride exposure alters Ca 2+ signaling and mitochondrial function in enamel cells. https://app.cochat.ai/papers/10.1126/scisignal.aay0086
The paper
Aulestia, F. J., Groeling, J., Bomfim, G. H. S., Costiniti, V., Manikandan, V., Chaloemtoem, A., Concepcion, A. R., Li, Y., Wagner, L. E., Idaghdour, Y., Yule, D. I., & Lacruz, R. S. (2020). Fluoride exposure alters Ca 2+ signaling and mitochondrial function in enamel cells. Science Signaling. https://doi.org/10.1126/scisignal.aay0086