The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans
Open accessAbstract
Ecuadorians who have a genetic mutation in the growth hormone receptor almost never die of cancer or diabetes complications, possibly because of high resistance to oxidative damage and low circulating insulin.
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Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
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A C. elegans mutant that lives twice as long as wild type
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Extending Healthy Life Span—From Yeast to Humans
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Self-citationMechanism of activation of protein kinase B by insulin and IGF-1.
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Self-citationGenes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
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Cited by
Fasting: molecular mechanisms and clinical applications
Longo, V. D., & Mattson, M. P. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.12.008 · Cited by 1,425
Self-citationLevine, M. E., Suarez, J. A., Brandhorst, S., Balasubramanian, P., Cheng, C.-W., Madia, F., Fontana, L., Mirisola, M. G., Guevara-Aguirre, J., Wan, J., et al. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.02.006 · Cited by 910
Self-citationThe Critical Role of Metabolic Pathways in Aging
Barzilai, N., Huffman, D. M., Muzumdar, R. H., & Bartke, A. (2012) · Diabetes · doi:10.2337/db11-1300 · Cited by 803
Obesity and diabetes: the increased risk of cancer and cancer-related mortality
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Interventions to slow aging in humans: are we ready?
Longo, V. D., Antebi, A., Bartke, A., Barzilai, N., Brown‐Borg, H. M., Caruso, C., Curiel, T. J., Cabo, R., Franceschi, C., Gems, D., et al. (2015) · Aging Cell · doi:10.1111/acel.12338 · Cited by 592
“(Guevara-Aguirre et al. , 2011; Steuerman et al. , 2011).”
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Metadata
- Authors
- Guevara-Aguirre, J., Balasubramanian, P., Guevara-Aguirre, M., Wei, M., Madia, F., Cheng, C.-W., Hwang, D., Martin-Montalvo, A., Saavedra, J., Ingles, S., de Cabo, R., Cohen, P., & Longo, V. D.
- Venue
- Science Translational Medicine
- Published
- 2011-02-16
- Volume
- 3
- Issue
- 70
- Pages
- 70ra13-70ra13
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- OpenAlex
- W2156136676
- Cited by
- 743
- References
- 74
- FWCI
- 47.31
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans. https://app.cochat.ai/papers/10.1126/scitranslmed.3001845
- The paper
- Guevara-Aguirre, J., Balasubramanian, P., Guevara-Aguirre, M., Wei, M., Madia, F., Cheng, C.-W., Hwang, D., Martin-Montalvo, A., Saavedra, J., Ingles, S., de Cabo, R., Cohen, P., & Longo, V. D. (2011). Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.3001845
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
