Skin Effector Memory T Cells Do Not Recirculate and Provide Immune Protection in Alemtuzumab-Treated CTCL Patients

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

Sallusto, F., Lenig, D., Förster, R., Lipp, M., & Lanzavecchia, A. (1999) · Nature · doi:10.1038/44385 · Cited by 5,846 · cited 2×

WHO-EORTC classification for cutaneous lymphomas

Willemze, R. (2005) · Blood · doi:10.1182/blood-2004-09-3502 · Cited by 3,803

Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

Sallusto, F., Geginat, J., & Lanzavecchia, A. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104702 · Cited by 3,067

Reshaping human antibodies for therapy

Riechmann, L., Clark, M., Waldmann, H., & Winter, G. P. (1988) · Nature · doi:10.1038/332323a0 · Cited by 1,565

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

Gebhardt, T., Wakim, L. M., Eidsmo, L., Reading, P. C., Heath, W. R., & Carbone, F. R. (2009) · Nature Immunology · doi:10.1038/ni.1718 · Cited by 1,157

The Vast Majority of CLA+ T Cells Are Resident in Normal Skin

Clark, R. A., Chong, B., Mirchandani, N., Brinster, N. K., Yamanaka, K.-I., Dowgiert, R. K., & Kupper, T. S. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.7.4431 · Cited by 796

Naive and memory T cells show distinct pathways of lymphocyte recirculation.

Mackay, C. R., Marston, W. L., & Dudler, L. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.171.3.801 · Cited by 787

Long-term Outcome of 525 Patients With Mycosis Fungoides and Sézary Syndrome

Kim, Y. H., Liu, H. L., Mraz‐Gernhard, S., Varghese, A., & Hoppe, R. T. (2003) · Archives of Dermatology · doi:10.1001/archderm.139.7.857 · Cited by 652

Sézary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors

Campbell, J. J., Clark, R. A., Watanabe, R., & Kupper, T. S. (2010) · Blood · doi:10.1182/blood-2009-11-251926 · Cited by 519

The window of therapeutic opportunity in multiple sclerosis

Coles, A. J., Cox, A., Page, E. L., Jones, J., Trip, S. A., Deans, J., Seaman, S. R., Miller, D. H., Hale, G., Waldmann, H., et al. (2005) · Journal of Neurology · doi:10.1007/s00415-005-0934-5 · Cited by 506

The human tissue-resident CCR5 + T cell compartment maintains protective and functional properties during inflammation

Davis, A. S. W., Roozen, H. N., Dufort, M. J., DeBerg, H. A., Delaney, M. A., Mair, F., Erickson, J. R., Slichter, C. K., Berkson, J. D., Klock, A. M., et al. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aaw8718 · Cited by 61

Benign T cells drive clinical skin inflammation in cutaneous T cell lymphoma

Vieyra-Garcia, P. A., Crouch, J. D., O’Malley, J. T., Seger, E. W., Yang, C., Teague, J. E., Vromans, A. M., Gehad, A. E., Win, T. S., Yu, Z., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.124233 · Cited by 58

Human dendritic cell subsets in vaccination

Palucka, K., & Banchereau, J. (2013) · Current Opinion in Immunology · doi:10.1016/j.coi.2013.05.001 · Cited by 57

Circulating and skin-derived Sézary cells: clonal but with phenotypic plasticity

Roelens, M., Delord, M., Ram‐Wolff, C., Marie‐Cardine, A., Alberdi, A., Maki, G., Homyrda, L., Bensussan, A., Bagot, M., Toubert, A., et al. (2017) · Blood · doi:10.1182/blood-2017-03-772996 · Cited by 57

Tissue‐resident T cells, in situ immunity and transplantation

Turner, D., Gordon, C. L., & Färber, D. L. (2014) · Immunological Reviews · doi:10.1111/imr.12149 · Cited by 57

Human skin-resident host T cells can persist long term after allogeneic stem cell transplantation and maintain recirculation potential

de Almeida, G. P., Lichtner, P., Eckstein, G., Brinkschmidt, T., Chu, C.-F., Sun, S., Reinhard, J., Mädler, S. C., Kloeppel, M., Verbeek, M., et al. (2022) · Science Immunology · doi:10.1126/sciimmunol.abe2634 · Cited by 58

Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection

Chen, C., Pouliquen, É., Broisat, A., Andreata, F., Racapé, M., Bruneval, P., Kessler, L., Ahmadi, M., Bacot, S., Saison, C., et al. (2017) · Journal of Clinical Investigation · doi:10.1172/jci93542 · Cited by 55

Immune status following alemtuzumab treatment in human CD52 transgenic mice

Turner, M. J., LaMorte, M. J., Chrétien, N., Havari, E., Roberts, B., Kaplan, J. M., & Siders, W. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.04.018 · Cited by 54

Dermal Regulatory T Cells Display Distinct Migratory Behavior That Is Modulated during Adaptive and Innate Inflammation

Chow, Z., Mueller, S. N., Deane, J. A., & Hickey, M. J. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203205 · Cited by 54

Epigenetic therapy overcomes treatment resistance in T cell prolymphocytic leukemia

Hasanali, Z. S., Saroya, B. S., Stuart, A., Shimko, S., Evans, J. J., Shah, M. V., Sharma, K., Leshchenko, V. V., Parekh, S. S., Loughran, T. P., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa5079 · Cited by 53

Pathogenesis and Therapy of Primary Cutaneous T-Cell Lymphoma: Collegium Internationale Allergologicum (CIA) Update 2020

Bobrowicz, M., Fassnacht, C., Ignatova, D., Chang, Y., Dimitriou, F., & Guenova, E. (2020) · International Archives of Allergy and Immunology · doi:10.1159/000509281 · Cited by 53

Central memory T cells are the most effective precursors of resident memory T cells in human skin

Matos, T. R., Gehad, A. E., Teague, J. E., Dyring‐Andersen, B., Benezeder, T., Dowlatshahi, M., Crouch, J. D., Watanabe, Y., O’Malley, J. T., Kupper, T. S., et al. (2022) · Science Immunology · doi:10.1126/sciimmunol.abn1889 · Cited by 52

Neutrophil perversion in demyelinating autoimmune diseases: Mechanisms to medicine

Casserly, C. S., Nantes, J. C., Hawkins, R. W., & Vallières, L. (2017) · Autoimmunity Reviews · doi:10.1016/j.autrev.2017.01.013 · Cited by 52

Skin-Resident Memory T Cells: Pathogenesis and Implication for the Treatment of Psoriasis

Vu, T. T., Koguchi‐Yoshioka, H., & Watanabe, R. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10173822 · Cited by 52

Modulation of tissue resident memory T cells by glucocorticoids after acute cellular rejection in lung transplantation

Snyder, M. E., Moghbeli, K., Bondonese, A., Craig, A., Popescu, I., Fan, L., Tabib, T., Lafyatis, R., Chen, K., Bittar, H. E. T., et al. (2022) · The Journal of Experimental Medicine · doi:10.1084/jem.20212059 · Cited by 49

More Than Skin Deep: Autophagy Is Vital for Skin Barrier Function

Sil, P., Wong, S., & Martinez, J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01376 · Cited by 48

Defining Th‐cell subsets in a classical and tissue‐specific manner: Examples from the skin

Eyerich, S., & Zielinski, C. E. (2014) · European Journal of Immunology · doi:10.1002/eji.201444891 · Cited by 52

Human Bone Marrow-Resident Natural Killer Cells Have a Unique Transcriptional Profile and Resemble Resident Memory CD8+ T Cells

Melsen, J. E., Lugthart, G., Vervat, C., Kiełbasa, S. M., van der Zeeuw, S. A. J., Buermans, H. P. J., Dam, M. M. V. O.-T., Lankester, A. C., & Schilham, M. W. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01829 · Cited by 49

Development and Function of Protective and Pathologic Memory CD4 T Cells

Jaigirdar, S. A., & MacLeod, M. K. L. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00456 · Cited by 49

Alemtuzumab Therapy for Leukemic Cutaneous T-Cell Lymphoma

Watanabe, R., Teague, J. E., Fisher, D. C., Kupper, T. S., & Clark, R. A. (2014) · JAMA Dermatology · doi:10.1001/jamadermatol.2013.10099 · Cited by 46

Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets

Saulīte, I., Hoetzenecker, W., Weidinger, S., Cozzio, A., Guenova, E., & Wehkamp, U. (2016) · BioMed Research International · doi:10.1155/2016/9717530 · Cited by 48

The Neutrophil: The Underdog That Packs a Punch in the Fight against Cancer

Avtenyuk, N. U., Visser, N., Bremer, E., & Wiersma, V. R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21217820 · Cited by 48

Insights into phenotypic and functional CD8 + TRM heterogeneity

Heeg, M., & Goldrath, A. W. (2023) · Immunological Reviews · doi:10.1111/imr.13218 · Cited by 45

A Perspective on the Interplay of Ultraviolet-Radiation, Skin Microbiome and Skin Resident Memory TCRαβ+ Cells

Patra, V., Laoubi, L., Nicolas, J.-F., Vocanson, M., & Wolf, P. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00166 · Cited by 42

Doxycycline is an NF-κB inhibitor that induces apoptotic cell death in malignant T-cells

Alexander‐Savino, C. V., Hayden, M. S., Richardson, C. T., Zhao, J., & Poligone, B. (2016) · Oncotarget · doi:10.18632/oncotarget.12488 · Cited by 42

Recent advances in understanding and managing cutaneous T-cell lymphomas

Brunner, P. M., Jonak, C., & Knobler, R. (2020) · F1000Research · doi:10.12688/f1000research.21922.1 · Cited by 42

Maintenance of quiescent immune memory in the bone marrow

Chang, H., & Radbruch, A. (2021) · European Journal of Immunology · doi:10.1002/eji.202049012 · Cited by 43

Rapid and sustained control of itch and reduction in Th2 bias by dupilumab in a patient with Sézary syndrome

Steck, O., Bertschi, N., Luther, F., van den Berg, J., Winkel, D. J., Holbro, A., & Schlapbach, C. (2020) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.17001 · Cited by 41

Mycosis fungoides and Sézary syndrome

Jonak, C., Tittes, J., Brunner, P. M., & Guenova, E. (2021) · JDDG Journal der Deutschen Dermatologischen Gesellschaft · doi:10.1111/ddg.14610 · Cited by 41

Lack of Type 2 Innate Lymphoid Cells Promotes a Type I-Driven Enhanced Immune Response in Contact Hypersensitivity

Rafei-Shamsabadi, D. A., van de Poel, S., Dorn, B., Kunz, S., Martin, S. F., Klose, C. S. N., Arnold, S. J., Tanriver, Y., Ebert, K., Diefenbach, A., et al. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.03.001 · Cited by 40

Naïve/memory T‐cell phenotypes in leukemic cutaneous T‐cell lymphoma: Putative cell of origin overlaps disease classification

Horna, P., Moscinski, L. C., Sokol, L., & Shao, H. (2018) · Cytometry Part B Clinical Cytometry · doi:10.1002/cyto.b.21738 · Cited by 40

Brentuximab vedotin in T-cell lymphoma

van der Weyden, C., Dickinson, M. J., Whisstock, J. C., & Prince, H. M. (2018) · Expert Review of Hematology · doi:10.1080/17474086.2019.1558399 · Cited by 40

Tissue-Resident Memory T Cells in the Liver—Unique Characteristics of Local Specialists

Bartsch, L. M., Damasio, M. P. S., Subudhi, S., & Drescher, H. K. (2020) · Cells · doi:10.3390/cells9112457 · Cited by 44

Cutaneous T-Cell Lymphoma: A Review with a Focus on Targeted Agents

Devata, S., & Wilcox, R. A. (2016) · American Journal of Clinical Dermatology · doi:10.1007/s40257-016-0177-5 · Cited by 40

Implications of Resident Memory T Cells for Transplantation

Beura, L. K., Rosato, P. C., & Masopust, D. (2016) · American Journal of Transplantation · doi:10.1111/ajt.14101 · Cited by 40

Tissue Immunity in the Bladder

Bowyer, G., Loudon, K. W., Suchánek, O., & Clatworthy, M. R. (2022) · Annual Review of Immunology · doi:10.1146/annurev-immunol-101220-032117 · Cited by 43

Skin resident memory CD8+ T cells are phenotypically and functionally distinct from circulating populations and lack immediate cytotoxic function

Seidel, J. A., Vukmanovic‐Stejic, M., Müller-Durovic, B., Patel, N. P., Fuentes‐Duculan, J., Henson, S. M., Krueger, J. G., Rustin, M. H. A., Nestle, F. O., Lacy, K. E., et al. (2018) · Clinical & Experimental Immunology · doi:10.1111/cei.13189 · Cited by 39

The human memory T cell compartment changes across tissues of the female reproductive tract

Davis, A. S. W., Vick, S. C., Pattacini, L., Voillet, V., Hughes, S. M., Lentz, G. M., Kirby, A. C., Fialkow, M. F., Gottardo, R., Hladik, F., et al. (2021) · Mucosal Immunology · doi:10.1038/s41385-021-00406-6 · Cited by 37

Generating long‐lived CD8+ T‐cell memory: Insights from epigenetic programs

Dogra, P., Ghoneim, H. E., Abdelsamed, H. A., & Youngblood, B. (2016) · European Journal of Immunology · doi:10.1002/eji.201545550 · Cited by 38

Human Anti-CCR4 Minibody Gene Transfer for the Treatment of Cutaneous T-Cell Lymphoma

Han, T. K., Abdel‐Motal, U. M., Chang, D.-K., Sui, J., Muvaffak, A., Campbell, J. J., Zhu, Q. K., Kupper, T. S., & Marasco, W. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044455 · Cited by 36

The Meaning of Immune Reconstitution after Alemtuzumab Therapy in Multiple Sclerosis

Rolla, S., Maglione, A., Mercanti, S. F. D., & Clerico, M. (2020) · Cells · doi:10.3390/cells9061396 · Cited by 36

Immunology Taught by Humans

Davis, M. M. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003385 · Cited by 35

Cat and Mouse: HIV Transcription in Latency, Immune Evasion and Cure/Remission Strategies

Delannoy, A., Poirier, M., & Bell, B. (2019) · Viruses · doi:10.3390/v11030269 · Cited by 35

Cusatuzumab for treatment of CD70‐positive relapsed or refractory cutaneous T‐cell lymphoma

Leupin, N., Zinzani, P. L., Morschhauser, F., Dalle, S., Maerevoet, M., Michot, J., Ribrag, V., Offner, F. C., Beylot-Barry, M., Moins‐Teisserenc, H., et al. (2021) · Cancer · doi:10.1002/cncr.34005 · Cited by 35

CCR4 + T cell recruitment to the skin in mycosis fungoides: potential contributions by thymic stromal lymphopoietin and interleukin-16

Tuzova, M. N., Richmond, J. M., Wolpowitz, D., Curiel‐Lewandrowski, C. N., Chaney, K. S., Kupper, T. S., & Cruikshank, W. W. (2014) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428194.2014.919634 · Cited by 35

A new molecular paradigm in mycosis fungoides and Sézary syndrome

Elenitoba‐Johnson, K. S. J., & Wilcox, R. A. (2016) · Seminars in Diagnostic Pathology · doi:10.1053/j.semdp.2016.11.002 · Cited by 35

Tissue-Resident Lymphocytes in Solid Organ Transplantation

Prosser, A., Kallies, A., & Lucas, M. (2017) · Transplantation · doi:10.1097/tp.0000000000002001 · Cited by 36

Alemtuzumab therapy changes immunoglobulin levels in peripheral blood and CSF

Möhn, N., Pfeuffer, S., Ruck, T., Groß, C. C., Skripuletz, T., Klotz, L., Wiendl, H., Stangel, M., & Meuth, S. G. (2019) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000000654 · Cited by 34

Skin Immunology and Rejection in VCA and Organ Transplantation

Leonard, D. A., Amin, K., Giele, H. P., Fildes, J. E., & Wong, J. K. F. (2020) · Current Transplantation Reports · doi:10.1007/s40472-020-00310-1 · Cited by 37

Two sides of the same coin: Protective versus pathogenic CD4 + resident memory T cells

Oja, A. E., van Lier, R. A. W., & Hombrink, P. (2022) · Science Immunology · doi:10.1126/sciimmunol.abf9393 · Cited by 35

Revealing the Complexity in CD8 T Cell Responses to Infection in Inbred C57B/6 versus Outbred Swiss Mice

Martin, M. D., Danahy, D. B., Hartwig, S. M., Harty, J. T., & Badovinac, V. P. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01527 · Cited by 35

Skin Resident Memory T Cells May Play Critical Role in Delayed-Type Drug Hypersensitivity Reactions

Schunkert, E. M., Shah, P. N., & Divito, S. J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.654190 · Cited by 34

Functional heterogeneity of human skin‐resident memory T cells in health and disease

Strobl, J., & Haniffa, M. A. (2023) · Immunological Reviews · doi:10.1111/imr.13213 · Cited by 34

Skin CD4+ Trm cells distinguish acute cutaneous lupus erythematosus from localized discoid lupus erythematosus/subacute cutaneous lupus erythematosus and other skin diseases

Zhao, Z., Zhu, H., Li, Q., Liao, W., Chen, K., Yang, M., Long, D., He, Z., Zhao, M., Wu, H., et al. (2022) · Journal of Autoimmunity · doi:10.1016/j.jaut.2022.102811 · Cited by 32

Novel therapies for cutaneous T-cell lymphoma: what does the future hold?

Guenova, E., Hoetzenecker, W., Rozati, S., Levesque, M. P., Dummer, R., & Cozzio, A. (2014) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2014.876407 · Cited by 32

Herpes simplex virus‐2 dynamics as a probe to measure the extremely rapid and spatially localized tissue‐resident T‐cell response

Schiffer, J. T., Swan, D. A., Prlic, M., & Lund, J. M. (2018) · Immunological Reviews · doi:10.1111/imr.12672 · Cited by 32

Formation of Tissue-Resident CD8+ T-Cell MemoryPreprint

Dijkgraaf, F. E., Kok, L., & Schumacher, T. N. (2021) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a038117 · Cited by 33

Skin T cells maintain their diversity and functionality in the elderly

Koguchi‐Yoshioka, H., Hoffer, E., Cheuk, S., Matsumura, Y., Vo, S., Kjellman, P., Grema, L., Ishitsuka, Y., Nakamura, Y., Okiyama, N., et al. (2021) · Communications Biology · doi:10.1038/s42003-020-01551-7 · Cited by 31

Safety and Danger Considerations of Novel Treatments for Atopic Dermatitis in Context of Primary Cutaneous Lymphomas

Kołkowski, K., Trzeciak, M., & Sokołowska-Wojdyło, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413388 · Cited by 30

Petri Net computational modelling of Langerhans cell Interferon Regulatory Factor Network predicts their role in T cell activation

Polak, M. E., Ung, C. Y., Masapust, J., Freeman, T. C., & Ardern‐Jones, M. R. (2017) · Scientific Reports · doi:10.1038/s41598-017-00651-5 · Cited by 32

Single-cell analysis of Sézary syndrome reveals novel markers and shifting gene profiles associated with treatment

Borcherding, N. C., Severson, K. J., Henderson, N., Ortolan, L. D. S., Rosenthal, A. C., Bellizzi, A. M., Liu, V., Link, B. K., Mangold, A. R., & Jabbari, A. (2022) · Blood Advances · doi:10.1182/bloodadvances.2021005991 · Cited by 30

Tissue-Specific Control of Tissue-Resident Memory T Cells

Liu, Y., Ma, C., & Zhang, N. (2018) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.2018025653 · Cited by 32

Transcriptional Analysis of T Cells Resident in Human Skin

Li, J., Olshansky, M., Carbone, F. R., & Ma, J. Z.-I. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148351 · Cited by 31

Diminished CD103 (aEb7) Expression on Resident T cells from the Female Genital Tract of HIV-positive women

Moylan, D. C., Goepfert, P., Kempf, M.-C., Saag, M. S., Richter, H. E., Mestecky, J. F., & Sabbaj, S. (2017) · Pathogens and Immunity · doi:10.20411/pai.v1i2.166 · Cited by 29

Monoclonal Antibodies

Geskin, L. J. (2015) · Dermatologic Clinics · doi:10.1016/j.det.2015.05.015 · Cited by 29

Cutaneous T cell immunity

Zareie, P., Weiss, E. S., Kaplan, D. H., & Mackay, L. K. (2025) · Nature Immunology · doi:10.1038/s41590-025-02145-3 · Cited by 29

Cutaneous T cell Lymphoma: an Update on Pathogenesis and Systemic Therapy

Chung, C. G., & Poligone, B. (2015) · Current Hematologic Malignancy Reports · doi:10.1007/s11899-015-0293-y · Cited by 28

The molecular cues regulating immune cell trafficking

Takeda, A., Sasaki, N., & Miyasaka, M. (2017) · Proceedings of the Japan Academy Series B · doi:10.2183/pjab.93.012 · Cited by 29

Tissue-Resident Memory T Cells in Skin Diseases: A Systematic Review

Emmanuel, T., Mistegård, J., Bregnhøj, A., Johansen, C., & Iversen, L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22169004 · Cited by 30

Epidermal Fatty Acid-Binding Protein: A Novel Marker in the Diagnosis of Dry Eye Disease in Sjögren Syndrome

Shinzawa, M., Doğru, M., Den, S., Ichijima, T., Higa, K., Kojima, T., Seta, N., Nomura, T., Tsubota, K., & Shimazaki, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19113463 · Cited by 28

Understanding the positive benefit:risk profile of alemtuzumab in relapsing multiple sclerosis: perspectives from the Alemtuzumab Clinical Development Program

Havrdová, E., Cohen, J. A., Horáková, D., Kovářová, I., & Meluzínová, E. (2017) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s143509 · Cited by 28

T cells in the skin: Lymphoma and inflammatory skin disease

Roediger, B., & Schlapbach, C. (2022) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2022.02.015 · Cited by 28

The role of chemokines in cutaneous immunosurveillance

Tan, S., Roediger, B., & Weninger, W. (2015) · Immunology and Cell Biology · doi:10.1038/icb.2015.16 · Cited by 28

Novel therapies for memory cells in autoimmune diseases

Bhargava, P., & Calabresi, P. A. (2015) · Clinical & Experimental Immunology · doi:10.1111/cei.12602 · Cited by 26

Protective and pathogenic roles of resident memory T cells in human skin disorders

Watanabe, R. (2019) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2019.06.001 · Cited by 26

Mycosis Fungoides and Sézary Syndrome: Microenvironment and Cancer Progression

Dobos, G., Lazaridou, I., & de Masson, A. (2023) · Cancers · doi:10.3390/cancers15030746 · Cited by 26

Intricate Relationship Between Adaptive and Innate Immune System in Allergic Contact Dermatitis.

Azeem, M., Kader, H. A., Kerstan, A., Hetta, ‏. F., Serfling, E., Goebeler, M., & Muhammad, K. (2020) · PubMed Central · Cited by 26

The Concept of Pathogenic TH2 Cells: Collegium Internationale Allergologicum Update 2021

Bertschi, N., Bazzini, C., & Schlapbach, C. (2021) · International Archives of Allergy and Immunology · doi:10.1159/000515144 · Cited by 26

Elevated Galectin-10 Expression of IL-22-Producing T Cells in Patients with Atopic Dermatitis

Noh, S., Jin, S., Park, C. O., Lee, Y. S., Lee, N., Lee, J., Shin, J. U., Kim, S. H., Yun, K. N., Kim, J. Y., et al. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2015.369 · Cited by 26

Heterogeneity and plasticity of tissue-resident memory T cells in skin diseases and homeostasis: a review

Liu, G., Wang, Z., & Li, S. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1378359 · Cited by 26

Antibody-Based Therapies for Cutaneous T-Cell Lymphoma

Welborn, M. E., & Duvic, M. A. (2018) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-0402-5 · Cited by 25

Tissue-resident memory-like T cells in tumor immunity: Clinical implications

Dhodapkar, M. V., & Dhodapkar, K. M. (2020) · Seminars in Immunology · doi:10.1016/j.smim.2020.101415 · Cited by 25

Advances and challenges in studying the tissue‐resident T cell compartment in the human female reproductive tract

Lund, J. M., Hladik, F., & Prlic, M. (2023) · Immunological Reviews · doi:10.1111/imr.13212 · Cited by 24

Tolerance induction via mixed chimerism in vascularized composite allotransplantation

Cetrulo, C. L., Drijkoningen, T., & Sachs, D. H. (2015) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000248 · Cited by 23

Memories that last: Dynamics of memory T cells throughout the body

Derksen, L. Y., Tesselaar, K., & Borghans, J. A. M. (2023) · Immunological Reviews · doi:10.1111/imr.13211 · Cited by 28

Holding our breath: the promise of tissue-resident memory T cells in lung cancer

Marceaux, C., Weeden, C. E., Gordon, C. L., & Asselin-Labat, M.-L. (2021) · Translational Lung Cancer Research · doi:10.21037/tlcr-20-819 · Cited by 22

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