Cutaneous T cell immunity

Sex differences in immune responses

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Topographical and Temporal Diversity of the Human Skin Microbiome

Grice, E. A., Kong, H. H., Conlan, S., Deming, C. B., Davis, J., Young, A. C., Program, N. C. S., Bouffard, G. G., Blakesley, R. W., Murray, P. R., et al. (2009) · Science · doi:10.1126/science.1171700 · Cited by 2,953 · see citing works

Innate or adaptive immunity? The example of natural killer cells

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The skin: an indispensable barrier

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Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis

Kong, H. H., Oh, J., Deming, C., Conlan, S., Grice, E. A., Beatson, M. A., Nomicos, E., Polley, E. C., Komarow, H. D., Program, N. C. S., et al. (2012) · Genome Research · doi:10.1101/gr.131029.111 · Cited by 1,808 · see citing works

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

Davar, D., Dzutsev, A. K., McCulloch, J. A., Rodrigues, R. R., Chauvin, J.-M., Morrison, R. M., Deblasio, R. N., Menna, C., Ding, Q., Pagliano, O., et al. (2021) · Science · doi:10.1126/science.abf3363 · Cited by 1,781 · cited 1× · see citing works

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

Baruch, E. N., Youngster, I., Ben-Betzalel, G., Ortenberg, R., Lahat, A., Katz, L., Adler, K., Dick-Necula, D., Raskin, S., Bloch, N., et al. (2021) · Science · doi:10.1126/science.abb5920 · Cited by 1,757 · see citing works

Skin immune sentinels in health and disease

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The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

Mackay, L. K., Rahimpour, A., Ma, J. Z., Collins, N., Stock, A. T., Hafon, M.-L., Vega-Ramos, J., Lauzurica, P., Mueller, S. N., Stefanovic, T., et al. (2013) · Nature Immunology · doi:10.1038/ni.2744 · Cited by 1,331 · cited 5× · see citing works

Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin

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Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

Gebhardt, T., Wakim, L. M., Eidsmo, L., Reading, P. C., Heath, W. R., & Carbone, F. R. (2009) · Nature Immunology · doi:10.1038/ni.1718 · Cited by 1,157 · see citing works

Compartmentalized Control of Skin Immunity by Resident Commensals

Naik, S., Bouladoux, N., Wilhelm, C., Molloy, M. J., Salcedo, R., Kastenmuller, W., Deming, C., Quinones, M., Koo, L., Conlan, S., et al. (2012) · Science · doi:10.1126/science.1225152 · Cited by 1,092 · see citing works

Normalizing the environment recapitulates adult human immune traits in laboratory mice

Beura, L. K., Hamilton, S. E., Bi, K., Schenkel, J. M., Odumade, O. A., Casey, K. A., Thompson, E. A., Fraser, K. A., Rosato, P. C., Filali-Mouhim, A., et al. (2016) · Nature · doi:10.1038/nature17655 · Cited by 1,072 · see citing works

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

Kumar, B. V., Ma, W., Miron, M., Granot, T., Guyer, R. S., Carpenter, D. J., Senda, T., Sun, X., Ho, S.-H., Lerner, H., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.08.078 · Cited by 1,068 · see citing works

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

Mackay, L. K., Minnich, M., Kragten, N. A. M., Liao, Y., Nota, B., Seillet, C., Zaid, A., Man, K., Preston, S., Freestone, D., et al. (2016) · Science · doi:10.1126/science.aad2035 · Cited by 1,010 · see citing works

Psoriasis pathogenesis and the development of novel targeted immune therapies

Hawkes, J. E., Chan, T. C.-C., & Krueger, J. G. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.07.004 · Cited by 981 · see citing works

Epithelial antimicrobial defence of the skin and intestine

Gallo, R. L., & Hooper, L. V. (2012) · Nature reviews. Immunology · doi:10.1038/nri3228 · Cited by 959 · see citing works

Mechanisms regulating skin immunity and inflammation

Pasparakis, M., Haase, I., & Nestle, F. O. (2014) · Nature reviews. Immunology · doi:10.1038/nri3646 · Cited by 943 · see citing works

Staphylococcus aureus in the lesions of atopic dermatitis

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Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

Jiang, X., Clark, R. A., Liu, L., Wagers, A. J., Fuhlbrigge, R. C., & Kupper, T. S. (2012) · Nature · doi:10.1038/nature10851 · Cited by 883 · see citing works

Innate lymphoid cells: A new paradigm in immunology

Eberl, G., Colonna, M., Di Santo, J. P., & McKenzie, A. N. J. (2015) · Science · doi:10.1126/science.aaa6566 · Cited by 878 · see citing works

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

Naik, S., Bouladoux, N., Linehan, J. L., Han, S.-J., Harrison, O. J., Wilhelm, C., Conlan, S., Himmelfarb, S., Byrd, A. L., Deming, C., et al. (2015) · Nature · doi:10.1038/nature14052 · Cited by 820 · see citing works

Immune surveillance in the skin: mechanisms and clinical consequences

Kupper, T. S., & Fuhlbrigge, R. C. (2004) · Nature reviews. Immunology · doi:10.1038/nri1310 · Cited by 805 · see citing works

The Vast Majority of CLA+ T Cells Are Resident in Normal Skin

Clark, R. A., Chong, B., Mirchandani, N., Brinster, N. K., Yamanaka, K.-I., Dowgiert, R. K., & Kupper, T. S. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.7.4431 · Cited by 796 · see citing works

Stratum Corneum Defensive Functions: An Integrated View

Elias, P. M. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23668.x · Cited by 781 · see citing works

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

Szabo, P. A., Levitin, H. M., Miron, M., Snyder, M. E., Senda, T., Yuan, J., Cheng, Y. L., Bush, E. C., Dogra, P., Thapa, P., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12464-3 · Cited by 756 · see citing works

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

Naik, S., Larsen, S. B., Gomez, N. C., Alaverdyan, K., Sendoel, A., Yuan, S., Polak, L., Kulukian, A., Chai, S., & Fuchs, E. (2017) · Nature · doi:10.1038/nature24271 · Cited by 745 · see citing works

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

Schenkel, J. M., Fraser, K. A., Beura, L. K., Pauken, K. E., Vezys, V., & Masopust, D. (2014) · Science · doi:10.1126/science.1254536 · Cited by 731 · see citing works

Dermcidin: A novel human antibiotic peptide secreted by sweat glands

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Macrophage heterogeneity in tissues: phenotypic diversity and functions

Gordon, S., Plüddemann, A., & Martínez, F. O. (2014) · Immunological Reviews · doi:10.1111/imr.12223 · Cited by 713 · see citing works

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light.

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Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation

Ali, N., Zirak, B., Rodriguez, R. S., Pauli, M. L., Truong, H.-A., Lai, K., Ahn, R., Corbin, K., Lowe, M. M., Scharschmidt, T. C., et al. (2017) · Cell · doi:10.1016/j.cell.2017.05.002 · Cited by 680 · see citing works

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

Cheuk, S., Schlums, H., Gallais Sérézal, I., Martini, E., Chiang, S. C., Marquardt, N., Gibbs, A., Detlofsson, E., Introini, A., Forkel, M., et al. (2017) · Immunity · doi:10.1016/j.immuni.2017.01.009 · Cited by 678 · see citing works

Location, location, location: Tissue resident memory T cells in mice and humans

Szabo, P. A., Miron, M., & Farber, D. L. (2019) · Science Immunology · doi:10.1126/sciimmunol.aas9673 · Cited by 651 · see citing works

Sensing and alarm function of resident memory CD8+ T cells

Schenkel, J., Fraser, K. A., Vezys, V., & Masopust, D. (2013) · Nature Immunology · doi:10.1038/ni.2568 · Cited by 648 · see citing works

A Role for Skin γδ T Cells in Wound Repair

Jameson, J., Ugarte, K., Chen, N., Yachi, P. P., Fuchs, E. V., Boismenu, R., & Havran, W. L. (2002) · Science · doi:10.1126/science.1069639 · Cited by 639 · see citing works

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

Mackay, L. K., Stock, A. T., Ma, J., Jones, C. M., Kent, S., Mueller, S. N., Heath, W., Carbone, F., & Gebhardt, T. (2012) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1202288109 · Cited by 638 · see citing works

Dynamic T cell migration program provides resident memory within intestinal epithelium

Masopust, D., Choo, D., Vezys, V., Wherry, E. J., Duraiswamy, J., Akondy, R., Wang, J., Casey, K. A., Barber, D. L., Kawamura, K. S., et al. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20090858 · Cited by 628 · see citing works

CD8+CD103+ Tumor–Infiltrating Lymphocytes Are Tumor-Specific Tissue-Resident Memory T Cells and a Prognostic Factor for Survival in Lung Cancer Patients

Djenidi, F., Adam, J., Goubar, A., Durgeau, A., Meurice, G., de Montpréville, V., Validire, P., Besse, B., & Mami-Chouaib, F. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402711 · Cited by 622 · see citing works

Functional Specializations of Human Epidermal Langerhans Cells and CD14+ Dermal Dendritic Cells

Klechevsky, E., Morita, R., Liu, M., Cao, Y., Coquery, S., Thompson-Snipes, L., Brière, F., Chaussabel, D., Zurawski, G., Palucka, K., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.07.013 · Cited by 616 · see citing works

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

Mackay, L. K., Wynne-Jones, E., Freestone, D., Pellicci, D. G., Mielke, L. A., Newman, D. M., Braun, A., Masson, F., Kallies, A., Belz, G. T., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.11.008 · Cited by 597 · see citing works

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

Watanabe, R., Gehad, A., Yang, C., Scott, L. L., Teague, J. E., Schlapbach, C., Elco, C. P., Huang, V., Matos, T. R., Kupper, T. S., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.3010302 · Cited by 569 · see citing works

MAIT cells are imprinted by the microbiota in early life and promote tissue repair

Constantinides, M. G., Link, V. M., Tamoutounour, S., Wong, A. C., Perez-Chaparro, P. J., Han, S.-J., Chen, Y. E., Li, K., Farhat, S., Weckel, A., et al. (2019) · Science · doi:10.1126/science.aax6624 · Cited by 567 · see citing works

Skin-resident memory CD8 + T cells trigger a state of tissue-wide pathogen alert

Ariotti, S., Hogenbirk, M. A., Dijkgraaf, F. E., Visser, L. L., Hoekstra, M. E., Song, J., Jacobs, H., Haanen, J. B. A. G., & Schumacher, T. N. (2014) · Science · doi:10.1126/science.1254803 · Cited by 534 · see citing works

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

Gebhardt, T., Whitney, P. G., Zaid, A., Mackay, L. K., Brööks, A. G., Heath, W. R., Carbone, F. R., & Mueller, S. N. (2011) · Nature · doi:10.1038/nature10339 · Cited by 529 · see citing works

Spontaneous Development of Psoriasis in a New Animal Model Shows an Essential Role for Resident T Cells and Tumor Necrosis Factor-α

Boyman, O., Hefti, H. P., Conrad, C., Nickoloff, B. J., Suter, M., & Nestle, F. O. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031482 · Cited by 521 · see citing works

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells

Roediger, B., Kyle, R. L., Yip, K. H., Sumaria, N., Guy, T. V., Kim, B., Mitchell, A. J., Tay, S. S., Jain, R., Forbes‐Blom, E., et al. (2013) · Nature Immunology · doi:10.1038/ni.2584 · Cited by 492 · see citing works

Immune checkpoint inhibitor–related dermatologic adverse events

Geisler, A. N., Phillips, G. S., M.S, D. M. B., Wu, J., Leung, D. Y. M., Moy, A. P., Kern, J. A., & Lacouture, M. E. (2020) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2020.03.132 · Cited by 490 · see citing works

TLR7 Ligands Induce Higher IFN-α Production in Females

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High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo

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Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of Haptens

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ILC1 Confer Early Host Protection at Initial Sites of Viral Infection

Weizman, O.-E., Adams, N. M., Schuster, I. S., Krishna, C., Pritykin, Y., Lau, C. M., Degli‐Esposti, M. A., Leslie, C. S., Sun, J. C.-Y., & O’Sullivan, T. E. (2017) · Cell · doi:10.1016/j.cell.2017.09.052 · Cited by 454 · see citing works

Nociceptive Sensory Fibers Drive Interleukin-23 Production from CD301b+ Dermal Dendritic Cells and Drive Protective Cutaneous Immunity

Kashem, S. W., Riedl, M. S., Yao, C., Honda, C. N., Vulchanova, L., & Kaplan, D. H. (2015) · Immunity · doi:10.1016/j.immuni.2015.08.016 · Cited by 448 · see citing works

CD103+ Tumor-Resident CD8+ T Cells Are Associated with Improved Survival in Immunotherapy-Naïve Melanoma Patients and Expand Significantly During Anti–PD-1 Treatment

Edwards, J. J., Wilmott, J. S., Madore, J., Gide, T. N., Quek, C. Y. J., Tasker, A. T., Ferguson, A. L., Chen, J., Hewavisenti, R., Hersey, P., et al. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-2257 · Cited by 446 · see citing works

Resident memory T cells in human health and disease

Clark, R. A. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.3010641 · Cited by 445 · see citing works

Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

Cheuk, S., Wikén, M., Blomqvist, L., Nylén, S., Talme, T., Ståhle, M., & Eidsmo, L. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1302313 · Cited by 421 · see citing works

Androgen receptor activity in T cells limits checkpoint blockade efficacy

Guan, X., Polesso, F., Wang, C., Sehrawat, A., Hawkins, R. M., Murray, S., THOMAS, G. V., Caruso, B., Thompson, R. F., Wood, M. A., et al. (2022) · Nature · doi:10.1038/s41586-022-04522-6 · Cited by 396 · see citing works

Microbial Symbiosis with the Innate Immune Defense System of the Skin

Gallo, R. L., & Nakatsuji, T. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.182 · Cited by 387 · see citing works

Cutting edge: IL-17-secreting innate lymphoid cells are essential for host defense against fungal infection

Gladiator, A., Wangler, N., Trautwein-Weidner, K., & LeibundGut-Landmann, S. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202924 · Cited by 382 · see citing works

Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin

Park, S. L., Buzzai, A. C., Rautela, J., Hor, J. L., Hochheiser, K., Effern, M., McBain, N., Wagner, T., Edwards, J. J., McConville, R., et al. (2018) · Nature · doi:10.1038/s41586-018-0812-9 · Cited by 378 · see citing works

Skin Effector Memory T Cells Do Not Recirculate and Provide Immune Protection in Alemtuzumab-Treated CTCL Patients

Clark, R. A., Watanabe, R., Teague, J. E., Schlapbach, C., Tawa, M. C., Adams, N., Dorosario, A. A., Chaney, K. S., Cutler, C. S., LeBoeuf, N. R., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003008 · Cited by 367 · see citing works

Antigen-Presenting Cells in the Skin

Kashem, S. W., Haniffa, M. A., & Kaplan, D. H. (2017) · Annual Review of Immunology · doi:10.1146/annurev-immunol-051116-052215 · Cited by 363 · see citing works

Mast cells in atopic dermatitis

Kawakami, T., Ando, T., Kimura, M., Wilson, B. S., & Kawakami, Y. (2009) · Current Opinion in Immunology · doi:10.1016/j.coi.2009.09.006 · Cited by 360 · see citing works

Vitiligo

Taı̈eb, A., & Picardo, M. (2009) · New England Journal of Medicine · doi:10.1056/nejmcp0804388 · Cited by 352 · see citing works

The Skin Immune System (SIS): Distribution and Immunophenotype of Lymphocyte Subpopulations in Normal Human Skin

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Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation

Zhu, J., Koelle, D. M., Cao, J., Vazquez, J., Huang, M. L., Hladik, F., Wald, A., & Corey, L. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20061792 · Cited by 340 · see citing works

A role for human skin–resident T cells in wound healing

Toulon, A., Breton, L., Taylor, K. R., Tenenhaus, M., Bhavsar, D., Lanigan, C., Rudolph, R., Jameson, J., & Havran, W. L. (2009) · Journal of Experimental Medicine · doi:10.1084/jem.20081787 · Cited by 339 · see citing works

A commensal strain of Staphylococcus epidermidis protects against skin neoplasia

Nakatsuji, T., Chen, T. H., Butcher, A. M., Trzoss, L., Nam, S., Shirakawa, K. T., Zhou, W. L., Oh, J., Otto, M. J., Fenical, W., et al. (2018) · Science Advances · doi:10.1126/sciadv.aao4502 · Cited by 327 · see citing works

Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

Adachi, T., Kobayashi, T., Sugihara, E., Yamada, T., Ikuta, K., Pittaluga, S., Saya, H., Amagai, M., & Nagao, K. (2015) · Nature Medicine · doi:10.1038/nm.3962 · Cited by 326 · see citing works

Basophils and allergic inflammation

Siracusa, M. C., Kim, B., Spergel, J. M., & Artis, D. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.07.046 · Cited by 320 · see citing works

Half- vs Full-Dose Trivalent Inactivated Influenza Vaccine (2004-2005)

Engler, R. J. M. (2008) · Archives of Internal Medicine · doi:10.1001/archinternmed.2008.513 · Cited by 319 · see citing works

Fermentation of Propionibacterium acnes, a Commensal Bacterium in the Human Skin Microbiome, as Skin Probiotics against Methicillin-Resistant Staphylococcus aureus

Shu, M., Wang, Y., Yu, J., Kuo, S., Coda, A. B., Jiang, Y., Gallo, R. L., & Huang, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055380 · Cited by 318 · see citing works

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

Park, S. L., Zaid, A., Hor, J. L., Christo, S. N., Prier, J. E., Davies, B., Alexandre, Y. O., Gregory, J. L., Russell, T., Gebhardt, T., et al. (2018) · Nature Immunology · doi:10.1038/s41590-017-0027-5 · Cited by 317 · see citing works

Persistence of skin-resident memory T cells within an epidermal niche

Zaid, A., Mackay, L. K., Rahimpour, A., Braun, A., Veldhoen, M., Carbone, F. R., Manton, J. H., Heath, W. R., & Mueller, S. N. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1322292111 · Cited by 306 · see citing works

Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

Richmond, J. M., Strassner, J. P., Zapata, L., Garg, M., Riding, R. L., Refat, M. A., Fan, X., Azzolino, V. N., Tovar‐Garza, A., Tsurushita, N., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aam7710 · Cited by 306 · see citing works

An update on the role of the sebaceous gland in the pathogenesis of acne

Makrantonaki, E., Gancevičienė, R., & Zouboulis, C. C. (2011) · Dermato-Endocrinology · doi:10.4161/derm.3.1.13900 · Cited by 301 · see citing works

Clinically resolved psoriatic lesions contain psoriasis-specific IL-17–producing αβ T cell clones

Matos, T. R., O’Malley, J. T., Lowry, E. L., Hamm, D. E., Kirsch, I. R., Robins, H. S., Kupper, T. S., Krueger, J. G., & Clark, R. A. (2017) · Journal of Clinical Investigation · doi:10.1172/jci93396 · Cited by 286 · see citing works

Developmental plasticity allows outside-in immune responses by resident memory T cells

Fonseca, R., Beura, L. K., Quarnstrom, C. F., Ghoneim, H. E., Fan, Y., Zebley, C. C., Scott, M. C., Fares-Frederickson, N. J., Wijeyesinghe, S., Thompson, E. A., et al. (2020) · Nature Immunology · doi:10.1038/s41590-020-0607-7 · Cited by 286 · see citing works

Resident memory T cells in the skin mediate durable immunity to melanoma

Malik, B. T., Byrne, K. T., Vella, J. L., Zhang, P., Shabaneh, T. B., Steinberg, S. M., Molodtsov, A. K., Bowers, J. S., Angeles, C. V., Paulos, C. M., et al. (2017) · Science Immunology · doi:10.1126/sciimmunol.aam6346 · Cited by 278 · see citing works

Tissue-resident memory CD8 + T cells continuously patrol skin epithelia to quickly recognize local antigen

Ariotti, S., Beltman, J. B., Chodaczek, G., Hoekstra, M. E., van Beek, A. E., Gomez, R., Ritsma, L., van Rheenen, J., Marée, A. F. M., Żal, T., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208927109 · Cited by 274 · see citing works

Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1

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Percutaneous Penetration of Quaternary Ammonium Compounds (QACs) Using in Vitro Three-Dimensional Human Skin Equivalents: Transport Mechanisms and Health Implications

Ran, M., Leng, X., Lv, Z., Xie, Y., Chen, W., Wang, X., Hu, M., Guo, X., Dong, Z., Xiang, J., et al. (2026) · Environmental Science & Technology · doi:10.1021/acs.est.5c16588

Development and Evaluation of Fluconazole-Loaded Nano-Emulgel for Enhanced Topical Therapy

Pandey, P., Gupta, D. N., Alam, M. S., & Bani, K. S. (2026) · Current pharmacogenomics and personalized medicine (Online)/Current pharmacogenomics and personalized medicine · doi:10.2174/0118756921419095260303081205

Fibroblast-encoded inflammatory memory orchestrates recurrent skin inflammation via NNMT-dependent metabolic remodelingPreprint

Zhou, Y., Li, K., Xie, Y., Su, C., Li, Z., Yang, Y., Qiao, P., Liu, W., Bai, Y., Xue, K., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.27.721223

Polyglutamic Acid‐Based Injectable Hydrogel: Design, Fabrication, and Evaluation in Accelerating Infected Wound Repair

Sun, Y., Lv, S., Lv, C., Ren, T., Wang, Y., Xiong, Y., Lu, Y., Li, R., Shi, Y., & Hou, X. (2026) · MedComm – Biomaterials and Applications · doi:10.1002/mba2.70054

Engineered bacterial membrane vesicles as transdermal cancer vaccines

Lu, J., Zhao, W., Shao, M., Chen, J., Xu, Y. J., Xu, H., Yan, X., Yin, C., Ma, Y., Yu, W., et al. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.115122

Human epidermal resident memory T cells: beyond the dermal perspective

Ogawa, Y., Sato, T., Minai, L., Kinoshita, M., Shimada, S., & Kawamura, T. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1903376

Dual anti-inflammatory topical therapy via drug co-encapsulation in solid lipid nanoparticles: enhanced cutaneous delivery and cytokine suppression

Morais, M. F., Silvestrini, A. V. P., Ramos, A. P., & Bentley, M. V. L. B. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108768

Chinese botanical drugs for mitigating epidermal growth factor receptor-targeted therapy-associated cutaneous toxicity: immune mechanisms and translational pathways

Lu, L., Yu, H., Yu, X., & Ren, W. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1931462

Female hormones enhance skin T cell expansion and suppress IFN-γ production

Bahri, R., Tontini, C., Kiss, O., Langton, A. K., Newton, V. L., Bell, M., & Bulfone‐Paus, S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1903552

MrgprD+ and MrgprA3+ afferents: Opposing neuroimmune control of psoriasiform inflammation

Yu, S., & Lee, C. (2026) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2026.08.005

Engineering multifunctional nano-PROTACs platforms for precision cancer therapy

Ning, Y., Wu, Y., Su, L., Liu, J., & Huang, F. (2026) · Science China Materials · doi:10.1007/s40843-026-4383-8

Tissue-Resident T Cells: Dynamic Players in Skin Immunity

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T Cells Make the Skin Home

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The Skin-Resident Immune Network

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Skin-resident T cells: the ups and downs of on site immunity

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T cells and the skin: from protective immunity to inflammatory skin disorders

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