The DOI matches its Crossref record; 63 of the 64 references it cites were found in a registry or an index.
Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis
Open accessAbstract
Chitinase 3–like 1 protects against lung injury but has a profibrotic role during the repair phase.
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“a relative excess of M1 macrophages leads to epithelial cell death and failure of repair such as that seen in acute exacerbation of IPF (AE-IPF)”
From The Role of Immune and Inflammatory Cells in Idiopathic Pulmonary Fibrosis (2018) · cites this paper as [21]
In the citing paper
“an excess of M2 macrophages leads to the aberrant and dysregulated repair responses that characterize progressive fibrosis (21)”
From The Role of Immune and Inflammatory Cells in Idiopathic Pulmonary Fibrosis (2018) · cites this paper as [21]
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Cites
Raghu, G., Collard, H. R., Egan, J. J., Martinez, F. J., Behr, J., Brown, K. K., Colby, T. V., Cordier, J.-F., Flaherty, K. R., Lasky, J. A., et al. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2009-040gl · Cited by 7,186
Alternative activation of macrophages
Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189
Webb, A. K. (2006) · Cited by 4,369
(2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.2.ats01 · Cited by 4,196
Martínez, F. O., Gordon, S., Locati, M., & Mantovani, A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.10.7303 · Cited by 2,399
Incidence and Prevalence of Idiopathic Pulmonary Fibrosis
Raghu, G., Weycker, D., Edelsberg, J., Bradford, W. Z., & Oster, G. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200602-163oc · Cited by 1,310
Tissue-Engineered Lungs for in Vivo Implantation
Petersen, T. H., Calle, E. A., Zhao, L., Lee, E. J., Gui, L., Raredon, M. S. B., Gavrilov, K., Yi, T., Zhuang, Z. W., Breuer, C. K., et al. (2010) · Science · doi:10.1126/science.1189345 · Cited by 1,189
Self-citationAcute Exacerbations of Idiopathic Pulmonary Fibrosis
Collard, H. R., Moore, B. B., Flaherty, K. R., Brown, K. K., Kaner, R. J., King, T. E., Lasky, J. A., Loyd, J. E., Noth, I., Olman, M. A., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-463pp · Cited by 1,130
Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury
Lee, C. G., Da Silva, C. A., Dela Cruz, C. S., Ahangari, F., Ma, B., Kang, M.-J., He, C.-H., Takyar, S., & Elias, J. A. (2011) · Annual Review of Physiology · doi:10.1146/annurev-physiol-012110-142250 · Cited by 896
Self-citationMechanisms of Pulmonary Fibrosis
Thannickal, V. J., Toews, G. B., White, E. S., Lynch, J. P., & Martínez, F. J. (2004) · Annual Review of Medicine · doi:10.1146/annurev.med.55.091902.103810 · Cited by 819
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Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C.-I., Ren, Z., et al. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201712-2410oc · Cited by 1,203
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C.-I., Anekalla, K. R., Joshi, N., Williams, K. J. N., et al. (2017) · Journal of Experimental Medicine · doi:10.1084/jem.20162152 · Cited by 1,133
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis
Moss, B. J., Ryter, S. W., & Rosas, I. O. (2021) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-042320-030240 · Cited by 852
Mechanisms of Organ Injury and Repair by Macrophages
Vannella, K. M., & Wynn, T. A. (2017) · Annual Review of Physiology · doi:10.1146/annurev-physiol-022516-034356 · Cited by 656
Chitinase-3 like-protein-1 function and its role in diseases
Zhao, T., Su, Z., Li, Y., Zhang, X., & You, Q. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00303-7 · Cited by 536
Metadata
- Authors
- Zhou, Y., Peng, H., Sun, H., Peng, X., Tang, C., Gan, Y., Chen, X., Mathur, A., Hu, B., Slade, M. D., Montgomery, R. R., Shaw, A. C., Homer, R. J., White, E. S., Lee, C.-M., Moore, M. W., Gulati, M., Geun Lee, C., Elias, J. A., & Herzog, E. L.
- Affiliations
- Yale University (US)
- Second Xiangya Hospital of Central South University (CN)
- University of Michigan (US)
- Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Yale School of Medicine, New Haven, CT 06520, USA.
- Brown University (US)
- Corresponding author
- Zhou, Yang
- Peng, Hong
- Sun, Huanxing
- Elias, Jack A.
- Herzog, Erica L.
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2014-06-11
- Volume
- 6
- Issue
- 240
- Pages
- 240ra76-240ra76
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4340473
- OpenAlex
- W2159203930
- Cited by
- 215
- References
- 64
- Citations by year
- 2026: 12 · 2025: 21 · 2024: 21 · 2023: 17 · 2022: 23 · 2021: 34 · 2020: 14 · 2019: 13 · 2018: 17 · 2017: 16 · 2016: 8 · 2015: 14 · 2014: 4
- FWCI
- 11.23
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR000142)
- U.S. Public Health Service (N01-HHS N272201100019C)
- National Institute on Aging (K24AG042489)
- National Heart, Lung, and Blood Institute (R01HL093017, U01HL108638, U01HL111016, U01HL112702, R01HL109233, HL-109033, R01HL109118, HL093017, U01HL109118, R01HL085083, P01HL114501, T32HL007749)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Studies on Chitinases and Chitosanases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Pulmonary Hypertension Research and Treatments
- Keywords
- YKL-40, idiopathic pulmonary fibrosis, pulmonary fibrosis, epithelial damage, fibroproliferation, alternative macrophage activation, myofibroblast transformation, fibroblast proliferation, apoptosis, disease progression, acute exacerbation, bleomycin-induced lung injury, circulating monocytes, extracellular matrix deposition, inflammation
- MeSH terms
- Chitinase-3-Like Protein 1, Animals, Enzyme-Linked Immunosorbent Assay, Female, Fibroblasts, Flow Cytometry, Humans, Lung, Pulmonary Fibrosis, Bone Marrow Transplantation, Apoptosis, Mice, Knockout, In Situ Nick-End Labeling, Lectins, Cell Proliferation, Mice, Adipokines
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