Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

Incidence and Outcomes of Acute Lung Injury

Rubenfeld, G. D., Caldwell, E., Peabody, E., Weaver, J., Martin, D. P., Neff, M., Stern, E. J., & Hudson, L. D. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050333 · Cited by 3,684 · see citing works

The global burden of asthma: executive summary of the GINA Dissemination Committee Report

Masoli, M., Fabian, D., Holt, S., Beasley, R. W., & Program, G. I. F. A. (. (2004) · Allergy · doi:10.1111/j.1398-9995.2004.00526.x · Cited by 3,521 · see citing works

Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

Robinson, D. S., Hamid, Q. A., Ying, S., Tsicopoulos, A., Barkans, J. R., Bentley, A. M., Corrigan, C. J., Durham, S. R., & Kay, A. B. (1992) · New England Journal of Medicine · doi:10.1056/nejm199201303260504 · Cited by 2,767 · see citing works

Interleukin-13: Central Mediator of Allergic Asthma

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Requirement for IL-13 Independently of IL-4 in Experimental Asthma

Grünig, G., Warnock, M. L., Wakil, A. E., Venkayya, R., Brombacher, F., Rennick, D. M., Sheppard, D., Mohrs, M., Donaldson, D. D., Locksley, R. M., et al. (1998) · Science · doi:10.1126/science.282.5397.2261 · Cited by 1,837 · see citing works

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

Zhu, Z., Homer, R., Wang, Z., Chen, Q., Geba, G. P., Wang, J., Zhang, Y., & Elias, J. A. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5909 · Cited by 1,704 · see citing works

Monocyte chemoattractant protein 1 in obesity and insulin resistance

Sartipy, P., & Loskutoff, D. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1133870100 · Cited by 1,199 · see citing works

The Global Burden of Asthma

Braman, S. S. (2006) · CHEST Journal · doi:10.1378/chest.130.1_suppl.4s · Cited by 1,178 · see citing works

The cytokine network in asthma and chronic obstructive pulmonary disease

Barnes, P. J. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36130 · Cited by 982 · see citing works

Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1

Lee, C. G., Homer, R. J., Zhu, Z., Lanone, S., Wang, X., Koteliansky, V., Shipley, J. M., Gotwals, P., Noble, P., Chen, Q., et al. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.6.809 · Cited by 940 · see citing works

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

Zurawski, G., & de Vries, J. E. (1994) · Immunology Today · doi:10.1016/0167-5699(94)90021-3 · Cited by 872 · see citing works

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

Hamid, Q. A., Azzawi, M., Ying, S., Moqbel, R., Wardlaw, A. J., Corrigan, C. J., Bradley, B., Durham, S. R., Collins, J. V., & Jeffery, P. K. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115166 · Cited by 833 · see citing works

Interleukin-4, -5, and -6 and Tumor Necrosis Factor-α in Normal and Asthmatic Airways: Evidence for the Human Mast Cell as a Source of these Cytokines

Bradding, P. H., Roberts, J. A., Britten, K. M., Montefort, S., Djukanović, R., Mueller, R., Heusser, C., Howarth, P. H., & Holgate, S. T. (1994) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.10.5.8179909 · Cited by 829 · see citing works

Acidic Mammalian Chitinase in Asthmatic Th2 Inflammation and IL-13 Pathway Activation

Zhu, Z., Zheng, T., Homer, R., Kim, Y., Chen, N. Y., Cohn, L. E., Hamid, Q. A., & Elias, J. A. (2004) · Science · doi:10.1126/science.1095336 · Cited by 805 · see citing works

Chitin induces accumulation in tissue of innate immune cells associated with allergy

Reese, T. A., Liang, H.-E., Tager, A. M., Luster, A. D., van Rooijen, N., Voehringer, D., & Locksley, R. M. (2007) · Nature · doi:10.1038/nature05746 · Cited by 748 · see citing works

Airway remodeling in asthma

Elias, J. A., Zhu, Z., Chupp, G. L., & Homer, R. (1999) · Journal of Clinical Investigation · doi:10.1172/jci8124 · Cited by 696 · see citing works

Interleukin‐13 in asthma pathogenesis

Wills‐Karp, M. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00215.x · Cited by 683 · see citing works

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family.

Hakala, B. E., White, C., & Recklies, A. D. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74461-5 · Cited by 643 · see citing works

A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma

Chupp, G. L., Lee, C. G., Jarjour, N. N., Shim, Y. M., Holm, C. T., He, S., Dziura, J. D., Reed, J., Coyle, A. J., Kiener, P. A., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa073600 · Cited by 546 · see citing works

Identification of a Novel Acidic Mammalian Chitinase Distinct from Chitotriosidase*

Boot, R., Blommaart, E., Swart, E., der Vlugt, K. G.-V., Bijl, N., Moe, C., Place, A., & Aerts, J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009886200 · Cited by 530 · see citing works

Human enzymatic activities related to the therapeutic administration of chitin derivatives

Muzzarelli, R. (1997) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/pl00000584 · Cited by 519 · see citing works

Prevalence and etiology of asthma

Beasley, R. W., Crane, J., Lai, C. K. W., & Pearce, N. E. (2000) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(00)90044-7 · Cited by 477 · see citing works

Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage

Garnero, P., Piperno, M., Gineyts, E., Christgau, S., Delmas, P. D., & Vignon, E. (2001) · Annals of the Rheumatic Diseases · doi:10.1136/ard.60.6.619 · Cited by 475 · see citing works

Effect of Variation in CHI3L1 on Serum YKL-40 Level, Risk of Asthma, and Lung Function

Ober, C., Tan, Z., Sun, Y., Possick, J. D., Pan, L., Nicolae, R. I., Radford, S., Parry, R. R., Heinzmann, A., Deichmann, K. A., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0708801 · Cited by 467 · see citing works

Cloning of a cDNA Encoding Chitotriosidase, a Human Chitinase Produced by Macrophages (*)

Boot, R., Renkema, G., Strijland, A., van Zonneveld, A. V., & Aerts, J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.44.26252 · Cited by 443 · see citing works

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

Lee, C. G., Hartl, D., Lee, G. R., Koller, B., Matsuura, H., Silva, C. A. D., Sohn, M. H., Cohn, L. E., Homer, R., Kozhich, A., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20081271 · Cited by 433 · see citing works

Genetic variants of IL-13 signalling and human asthma and atopy

Heinzmann, A. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.4.549 · Cited by 428 · see citing works

CD4+ Invariant T-Cell–Receptor+ Natural Killer T Cells in Bronchial Asthma

Akbari, O., Faul, J. L., Hoyte, E. G., Berry, G. J., Wahlström, J., Kronenberg, M., DeKruyff, R. H., & Umetsu, D. T. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa053614 · Cited by 420 · see citing works

The Human Chitotriosidase Gene

Boot, R. G., Renkema, G. H., Verhoek, M., Strijland, A., Bliek, J., de Meulemeester, T. M. A. M. O., Mannens, M. M. A. M., & Aerts, J. M. F. G. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.40.25680 · Cited by 416 · see citing works

IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells.

Bochner, B. S., Klunk, D. A., Sterbinsky, S. A., Coffman, R. L., & Schleimer, R. P. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.154.2.799 · Cited by 412 · see citing works

New insights into the pathogenesis of asthma

Elias, J. A., Lee, C. G., Zheng, T., Ma, B., Homer, R. J., & Zhu, Z. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17748 · Cited by 407 · see citing works

The role of IL-13 and its receptor in allergy and inflammatory responses

de Vries, J. E. (1998) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(98)70080-6 · Cited by 405 · see citing works

Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer.

Johansen, J. S. (2006) · PubMed · Cited by 404 · see citing works

Immunological activity of chitin and its derivatives

Nishimura, K., Nishimura, S., Nishi, N., SAIKI, I., Tokura, S., & Azuma, I. (1984) · Vaccine · doi:10.1016/s0264-410x(98)90039-1 · Cited by 394 · see citing works

Chitin regulation of immune responses: an old molecule with new roles

Lee, C. G., Silva, C. A. D., Lee, J.-Y., Hartl, D., & Elias, J. A. (2008) · Current Opinion in Immunology · doi:10.1016/j.coi.2008.10.002 · Cited by 393 · see citing works

Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD.

(2006) · Journal of Neuroinflammation · doi:10.1186/1742-2094-3-27 · Cited by 393 · see citing works

The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways

Recklies, A. D., White, C., & Ling, H. (2002) · Biochemical Journal · doi:10.1042/bj20020075 · Cited by 389 · see citing works

IL-13 expression at the sites of allergen challenge in patients with asthma

Huang, S. K., Xiao, H., Kleine‐Tebbe, J., Paciotti, G. F., Marsh, D. G., Lichtenstein, L. M., & Liu, M. C. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.5.2688 · Cited by 371 · see citing works

ANTIBIOTICS THAT INHIBIT FUNGAL CELL WALL DEVELOPMENT

Debono, M., & Gordee, R. S. (1994) · Annual Review of Microbiology · doi:10.1146/annurev.mi.48.100194.002351 · Cited by 371 · see citing works

Purification and Characterization of Human Chitotriosidase, a Novel Member of the Chitinase Family of Proteins (*)

Renkema, G., Boot, R., Muijsers, A. O., Donker-Koopman, W., & Aerts, J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.5.2198 · Cited by 364 · see citing works

Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family

Funkhouser, J. D., & Aronson, N. N. (2007) · BMC Evolutionary Biology · doi:10.1186/1471-2148-7-96 · Cited by 341 · see citing works

Serum YKL-40, A New Prognostic Biomarker in Cancer Patients?

Johansen, J. S., Jensen, B. V., Roslind, A., Nielsen, D. L., & Price, P. A. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0011 · Cited by 340 · see citing works

Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity.

van Eijk, M., van Roomen, C., Renkema, G., Bussink, A. P., Andrews, L., Blommaart, E., Sugar, A., Verhoeven, A., Boot, R., & Aerts, J. (2005) · International Immunology · doi:10.1093/intimm/dxh328 · Cited by 331 · see citing works

Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma

Humbert, M. J. C., Durham, S. R., Kimmitt, P. T., Powell, N., Assoufi, B., Pfister, R., Menz, G., Kay, A. B., & Corrigan, C. J. (1997) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(97)70028-9 · Cited by 314 · see citing works

Evolution of Mammalian Chitinase(-Like) Members of Family 18 Glycosyl Hydrolases

Bussink, A. P., Speijer, D., Aerts, J., & Boot, R. (2007) · Genetics · doi:10.1534/genetics.107.075846 · Cited by 301 · see citing works

Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation.

Rehli, M., Krause, S., & Andreesen, R. (1997) · Genomics · doi:10.1006/geno.1997.4778 · Cited by 297 · see citing works

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

Shao, R., Hamel, K. M., Petersen, L. M., Cao, Q. J., Arenas, R. B., Bigelow, C., Bentley, B. A., & Yan, W. (2009) · Oncogene · doi:10.1038/onc.2009.292 · Cited by 293 · see citing works

Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 production

Shibata, Y., Metzger, W. J., & Myrvik, Q. N. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.5.2462 · Cited by 285 · see citing works

Chitin Is a Size-Dependent Regulator of Macrophage TNF and IL-10 Production

Silva, C. A. D., Chalouni, C. M., Williams, A., Hartl, D., Lee, C. G., & Elias, J. A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0802113 · Cited by 279 · see citing works

Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease.

Shahabuddin, M., Toyoshima, T., Aikawa, M., et al. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.9.4266 · Cited by 279 · see citing works

A Macrophage Protein, Ym1, Transiently Expressed during Inflammation Is a Novel Mammalian Lectin*

Chang, N., Hung, S.-I., Hwa, K., Kato, I., Chen, J.-E., Liu, C.-H., & Chang, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010417200 · Cited by 276 · see citing works

Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation

Ray, A., & Cohn, L. E. (1999) · Journal of Clinical Investigation · doi:10.1172/jci8204 · Cited by 273 · see citing works

A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells

Kawamura, K., Shibata, T., Saget, O., Peel, D. A., & Bryant, P. J. (1999) · Development · doi:10.1242/dev.126.2.211 · Cited by 271 · see citing works

Identification of proteins secreted by human osteoblastic cells in culture

Johansen, J. S., Williamson, M. K., Rice, J. S., et al. (1992) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650070506 · Cited by 269 · see citing works

Chitinase and Fizz Family Members Are a Generalized Feature of Nematode Infection with Selective Upregulation of Ym1 and Fizz1 by Antigen-Presenting Cells

Nair, M. G., Gallagher, I. J., Taylor, M. D., Loke, P., Coulson, P. S., Wilson, R. A., Maizels, R. M., & Allen, J. E. (2004) · Infection and Immunity · doi:10.1128/iai.73.1.385-394.2005 · Cited by 252 · see citing works

Transcriptional Regulation of CHI3L1, a Marker Gene for Late Stages of Macrophage Differentiation

Rehli, M., Niller, H. H., Ammon, C., Langmann, S., Schwarzfischer, L., Andreesen, R., & Krause, S. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306792200 · Cited by 249 · see citing works

Serum YKL-40 is increased in patients with hepatic fibrosis

Johansen, J. S., Christoffersen, P., Møller, S., Price, P. A., Henriksen, J. H., Garbarsch, C., & Bendtsen, F. (2000) · Journal of Hepatology · doi:10.1016/s0168-8278(00)80095-1 · Cited by 249 · see citing works

TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation

Silva, C. A. D., Hartl, D., Liu, W., Lee, C. G., & Elias, J. A. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.6.4279 · Cited by 245 · see citing works

Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts

Horowitz, J. C., Rogers, D. S., Sharma, V., Vittal, R., White, E. S., Cui, Z., & Thannickal, V. J. (2006) · Cellular Signalling · doi:10.1016/j.cellsig.2006.10.001 · Cited by 241 · see citing works

Pitfalls, Problems, and Progress in Bronchopulmonary Dysplasia

Bhandari, A., & Bhandari, V. (2009) · PEDIATRICS · doi:10.1542/peds.2008-1962 · Cited by 239 · see citing works

Crystal Structure and Carbohydrate-binding Properties of the Human Cartilage Glycoprotein-39

Fusetti, F., Pijning, T., Kalk, K. H., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303137200 · Cited by 239 · see citing works

TH2 Cytokines and Allergic Challenge Induce Ym1 Expression in Macrophages by a STAT6-dependent Mechanism

Welch, J. S., Escoubet‐Lozach, L., Sykes, D. B., Liddiard, K., Greaves, D. R., & Glass, C. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205873200 · Cited by 233 · see citing works

The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha

Ling, H., & Recklies, A. D. (2004) · Biochemical Journal · doi:10.1042/bj20040099 · Cited by 225 · see citing works

Identification of a 38-kDa Heparin-binding Glycoprotein (gp38k) in Differentiating Vascular Smooth Muscle Cells as a Member of a Group of Proteins Associated with Tissue Remodeling

Shackelton, L. M., Mann, D., & Millis, A. J. T. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.13076 · Cited by 219 · see citing works

YKL-40 Is Elevated in Patients with Chronic Obstructive Pulmonary Disease and Activates Alveolar Macrophages

Letuve, S., Kozhich, A., Arouche, N., Grandsaigne, M., Reed, J., Dombret, M.-C., Kiener, P. A., Aubier, M., Coyle, A. J., & Pretolani, M. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.7.5167 · Cited by 217 · see citing works

Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway.

Kzhyshkowska, J., Mamidi, S., Gratchev, A., Kremmer, E., Schmuttermaier, C., Krusell, L., Haus, G., Utikal, J., Schledzewski, K., Scholtze, J., et al. (2006) · Blood · doi:10.1182/blood-2005-07-2843 · Cited by 216 · see citing works

Human cartilage glycoprotein‐39 as a candidate autoantigen in rheumatoid arthritis

Verheijden, G. F. M., Rijnders, A. W. M., Bos, E. S., et al. (1997) · Arthritis & Rheumatism · doi:10.1002/art.1780400616 · Cited by 210 · see citing works

Isolation and Sequence of a Novel Human Chondrocyte Protein Related to Mammalian Members of the Chitinase Protein Family

Hu, B., Trinh, K., Figueira, W. F., et al. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.32.19415 · Cited by 203 · see citing works

neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors.

Morrison, B. W., & Leder, P. (1994) · PubMed · Cited by 200 · see citing works

Airway wall remodelling in asthma

Redington, A. E., & Howarth, P. H. (1997) · Thorax · doi:10.1136/thx.52.4.310 · Cited by 200 · see citing works

Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice

Shibata, Y., Foster, L. A., Metzger, W. J., et al. (1997) · Infection and Immunity · doi:10.1128/iai.65.5.1734-1741.1997 · Cited by 198 · see citing works

Studies on YKL-40 in knee joints of patients with rheumatoid arthritis and osteoarthritis. Involvement of YKL-40 in the joint pathology

Volck, B., Johansen, J. S., Stoltenberg, M., et al. (2001) · Osteoarthritis and Cartilage · doi:10.1053/joca.2000.0377 · Cited by 185 · see citing works

YKL-40, a biomarker of inflammation, is elevated in patients with type 2 diabetes and is related to insulin resistance

Rathcke, C. N., Johansen, J. S., & Vestergaard, H. (2006) · Inflammation Research · doi:10.1007/s00011-005-0010-8 · Cited by 179 · see citing works

Interleukin (IL)-4–independent Induction of Immunoglobulin (Ig)E, and Perturbation of T Cell Development in Transgenic Mice Expressing IL-13

Emson, C. L., Bell, S. E., Jones, A., Wisden, W., & McKenzie, A. N. J. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.2.399 · Cited by 177 · see citing works

Synthesis, sorting, and processing into distinct isoforms of human macrophage chitotriosidase.

Renkema, G., Boot, R., Strijland, A., Donker-Koopman, W., van den Berg, M., Muijsers, A. O., & Aerts, J. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00279.x · Cited by 176 · see citing works

Expression of the Ym2 Lectin-binding Protein Is Dependent on Interleukin (IL)-4 and IL-13 Signal Transduction

Webb, D. C., McKenzie, A. N. J., & Foster, P. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106223200 · Cited by 175 · see citing works

The chitin crystallite in arthropod cuticle

Neville, A. C., Parry, D. A. D., & Woodhead-Galloway, J. (1976) · Journal of Cell Science · doi:10.1242/jcs.21.1.73 · Cited by 172 · see citing works

Human Chitinases and Chitinase-Like Proteins as Indicators for Inflammation and Cancer

Kzhyshkowska, J. G., Gratchev, A. N., & Goerdt, S. (2007) · Biomarker Insights · doi:10.1177/117727190700200023 · Cited by 171 · see citing works

Oral Administration of Chitin Down-Regulates Serum IgE Levels and Lung Eosinophilia in the Allergic Mouse

Shibata, Y., Foster, L. A., Bradfield, J. F., et al. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.3.1314 · Cited by 168 · see citing works

Inflammatory Cytokines Induce Production of CHI3L1 by Articular Chondrocytes

Recklies, A. D., Ling, H., White, C., & Bernier, S. M. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510146200 · Cited by 165 · see citing works

Serum YKL-40, a Potential New Marker of Disease Activity in Patients with Inflammatory Bowel Disease

Vind, I., Johansen, J. S., Price, P. A., et al. (2003) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310000537 · Cited by 156 · see citing works

Human chitinases and chitinase-like proteins as indicators for inflammation and cancer.

Kzhyshkowska, J. G., Gratchev, A. N., & Goerdt, S. (2007) · PubMed Central · Cited by 154 · see citing works

Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease

Saitou, Y. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i4.476 · Cited by 154 · see citing works

Biochemical Characterization of Endogenously Formed Eosinophilic Crystals in the Lungs of Mice*

Guo, L., Johnson, R. S., & Schuh, J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.11.8032 · Cited by 149 · see citing works

Serum levels of YKL-40 and PIIINP as prognostic markers in patients with alcoholic liver disease

Nøjgaard, C., Johansen, J. S., Christensen, E., Skovgaard, L. T., Price, P. A., & Becker, U. (2003) · Journal of Hepatology · doi:10.1016/s0168-8278(03)00184-3 · Cited by 146 · see citing works

Marked Differences in Tissue-specific Expression of Chitinases in Mouse and Man

Boot, R., Bussink, A. P., Verhoek, M., de Boer, P. D., Moorman, A., & Aerts, J. (2005) · Journal of Histochemistry and Cytochemistry · doi:10.1369/jhc.4a6547.2005 · Cited by 146 · see citing works

Chitinase 3-Like-1 (CHI3L1): A Putative Disease Marker at the Interface of Proteomics and Glycomics

Coffman, F. D. (2008) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408360802334743 · Cited by 146 · see citing works

Polymorphisms and haplotypes of acid mammalian chitinase are associated with bronchial asthma.

Bierbaum, S., Nickel, R., Koch, A., Lau, S., Deichmann, K., Wahn, U., Superti-Furga, A., & Heinzmann, A. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200506-890oc · Cited by 145 · see citing works

Chitinases in biological control

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