The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Human COL7A1 -corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa
Open accessAbstract
Patient-specific iPSCs were derived, corrected, and differentiated into human skin grafts for the treatment of recessive dystrophic epidermolysis bullosa.
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“Furthermore, skin organoids can be readily generated from patient-derived cells and used to model genetic disorders, such as epidermolysis bullosa”
From Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells (2022) · cites this paper as [60]
Experimental — accuracy not yet measuredIn the citing paper
“It has been shown that human skin equivalents can be created entirely from fibroblasts and keratinocytes generated from patients’ iPSCs, and that healthy cells can be generated from reprogrammed cells from patients with RDEB (153, 154).”
From Wound repair and regeneration: Mechanisms, signaling, and translation (2014) · cites this paper as [154]
In the citing paper
“and that healthy cells can be generated from reprogrammed cells from patients with RDEB (153, 154).”
From Wound repair and regeneration: Mechanisms, signaling, and translation (2014) · cites this paper as [154]
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Cites
The Sequence Alignment/Map format and SAMtools
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Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nature Protocols · doi:10.1038/nprot.2008.211 · Cited by 35,890
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
Wang, K., Li, M., & Hakonarson, H. H. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq603 · Cited by 14,724
Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification
Fine, J., Bruckner‐Tuderman, L., Eady, R. A. J., Bauer, E. A., Bauer, J. W., Has, C., Heagerty, A., Hintner, H., Hovnanian, A., Jonkman, M. F., et al. (2014) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2014.01.903 · Cited by 934
Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette
Sommer, C. A., Stadtfeld, M., Murphy, G. J., Hochedlinger, K., Kotton, D. N., & Mostoslavsky, G. (2009) · Stem Cells · doi:10.1634/stemcells.2008-1075 · Cited by 676
Mavilio, F., Pellegrini, G., Ferrari, S., Nunzio, F. D., Iorio, E. D., Recchia, A., Maruggi, G., Ferrari, G., Provasi, E., Bonini, C., et al. (2006) · Nature Medicine · doi:10.1038/nm1504 · Cited by 668
Somers, A., Jean, J.-C., Sommer, C. A., Omari, A., Ford, C. C., Mills, J. A., Ying, L., Sommer, A. G., Jean, J. M., Smith, B. W., et al. (2010) · Stem Cells · doi:10.1002/stem.495 · Cited by 423
iPS cells: a game changer for future medicine
Inoue, H., Nagata, N., Kurokawa, H., & Yamanaka, S. (2014) · The EMBO Journal · doi:10.1002/embj.201387098 · Cited by 414
Sebastiano, V., Maeder, M. L., Angstman, J. F., Haddad, B., Khayter, C., Yeo, D. T., Goodwin, M. J., Hawkins, J. S., Ramirez, C. L., Batista, L. F. Z., et al. (2011) · Stem Cells · doi:10.1002/stem.718 · Cited by 311
Self-citation
Research works printed but not linked: 1
- Siprashvili Z., Nguyen N., Gorell E., Khuu P., Furukawa L., Lorenz H., Leung T., Keene D., Khavari P., Marinkovich M., Lane A., Phase I clinical trial of genetically corrected autologous epidermal keratinocytes for recessive dystrophic epidermolysis bullosa. J. Invest. Dermatol. 134, S75 (2014).
Cited by
Sorted by citations
Wound repair and regeneration: Mechanisms, signaling, and translation
Eming, S. A., Martin, P., & Tomic-Canic, M. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009337 · Cited by 3,562
Genome-editing Technologies for Gene and Cell Therapy
Maeder, M. L., & Gersbach, C. A. (2016) · Molecular Therapy · doi:10.1038/mt.2016.10 · Cited by 736
Advanced drug delivery systems and artificial skin grafts for skin wound healing
Kim, H. S., Sun, X., Lee, J., Kim, H., Fu, X., & Leong, K. W. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.12.014 · Cited by 639
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion
Huang, Y.-W. A., Zhou, B., Wernig, M., & Südhof, T. C. (2017) · Cell · doi:10.1016/j.cell.2016.12.044 · Cited by 528
Self-citationInduced Pluripotent Stem Cells Meet Genome Editing
Hockemeyer, D., & Jaenisch, R. (2016) · Cell Stem Cell · doi:10.1016/j.stem.2016.04.013 · Cited by 499
“, 2016) and to derive isogeneic cell pairs of COL7A1-corrected iPSCs derived from patients with dystrophic epidermolysis bullosa (Sebastiano et al., 2014).”
Background
Metadata
- Authors
- Sebastiano, V., Zhen, H. H., Haddad, B., Bashkirova, E., Melo, S. P., Wang, P., Leung, T. L., Siprashvili, Z., Tichy, A., Li, J., Ameen, M., Hawkins, J., Lee, S., Li, L., Schwertschkow, A., Bauer, G., Lisowski, L., Kay, M. A., Kim, S. K., Lane, A. T., Wernig, M., & Oro, A. E.
- Affiliations
- Institute for Stem Cell Biology and Regenerative Medicine (US)
- Stanford Medicine (US)
- Stanford University (US)
- University of California, Davis (US)
- Corresponding author
- Sebastiano, Vittorio
- Zhen, Hanson Hui
- Wernig, Marius
- Oro, Anthony E.
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2014-11-26
- Volume
- 6
- Issue
- 264
- Pages
- 264ra163-264ra163
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4428910
- OpenAlex
- W2085600205
- Cited by
- 213
- References
- 39
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 9 · 2023: 12 · 2022: 17 · 2021: 29 · 2020: 15 · 2019: 21 · 2018: 23 · 2017: 27 · 2016: 22 · 2015: 23 · 2014: 3
- FWCI
- 10.26
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- National Heart, Lung, and Blood Institute (R01HL064274)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR055914, K08AR066661, T32AR007422)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Pluripotent Stem Cells Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
- Keywords
- recessive dystrophic epidermolysis bullosa, COL7A1, type VII collagen, induced pluripotent stem cells, genome editing, keratinocytes, organotypic culture, genodermatosis, squamous cell carcinoma
- MeSH terms
- Animals, Base Sequence, Genes, Recessive, Humans, Molecular Sequence Data, Mutation, Genetic Therapy, Keratinocytes, Genome, Human, Epidermolysis Bullosa Dystrophica, Sequence Analysis, DNA, Genetic Predisposition to Disease, Collagen Type VII, Mice, Induced Pluripotent Stem Cells, Homologous Recombination
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