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Immunomodulatory role of thrombin in cancer progression

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Platelets subvert antitumor efficacy of T cell-recruiting bispecific antibodies

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Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

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Soluble immune checkpoint molecules in cancer risk, outcomes prediction, and therapeutic applications

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Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy

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GARP as a Therapeutic Target for the Modulation of Regulatory T Cells in Cancer and Autoimmunity

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The Complex Role of Thrombin in Cancer and Metastasis: Focus on Interactions with the Immune System

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Treatment with therapeutic anticoagulation is not associated with immunotherapy response in advanced cancer patients

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Therapeutic activity of GARP:TGF-β1 blockade in murine primary myelofibrosis

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Protein Corona Gold Nanoparticles Fingerprinting Reveals a Profile of Blood Coagulation Proteins in the Serum of HER2-Overexpressing Breast Cancer Patients

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Precise fibrin decomposition and tumor mechanics modulation with hydroxyethyl starch-based smart nanomedicine for enhanced antitumor efficacy

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Biodegradable electrospun nanofibrous platform integrating antiplatelet therapy-chemotherapy for preventing postoperative tumor recurrence and metastasis

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Interactions between platelets and the cancer immune microenvironment

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Systemic inflammation is associated with inferior disease control and survival in stage III non-small cell lung cancer

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Interplay of stromal tumor-infiltrating lymphocytes, normal colonic mucosa, cancer-associated fibroblasts, clinicopathological data and the immunoregulatory molecules of patients diagnosed with colorectal cancer

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Platelets in cancer and immunotherapy: functional dynamics and therapeutic opportunities

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Concomitant Medication Effects on Immune Checkpoint Inhibitor Efficacy and Toxicity

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Engineering Cell‐Based Systems for Smart Cancer Therapy

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Exploitation of platelets for antitumor drug delivery and modulation of the tumor immune microenvironment

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Improved survival of advanced melanoma patients receiving immunotherapy with concomitant antithrombotic therapy – A multicenter study on 2419 patients from the prospective skin cancer registry ADOReg

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Platelets for advanced drug delivery in cancer

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GARP: A Key Target to Evaluate Tumor Immunosuppressive Microenvironment

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Artificial Intelligence–Powered Hematoxylin and Eosin Analyzer Reveals Distinct Immunologic and Mutational Profiles among Immune Phenotypes in Non–Small-Cell Lung Cancer

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Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets of Oncogenic NF-κB Signaling

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Coagulation Protease-Driven Cancer Immune Evasion: Potential Targets for Cancer Immunotherapy

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Single‐Domain Antibody‐Based TCR‐Like CAR‐T: A Potential Cancer Therapy

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Decoding the role of platelets in tumour metastasis: enigmatic accomplices and intricate targets for anticancer treatments

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Mean platelet volume, thrombocytosis, and survival in non-small cell lung cancer patients treated with first-line pembrolizumab alone or with chemotherapy

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mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer

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Large-Scale Transcriptome Data Analysis Identifies KIF2C as a Potential Therapeutic Target Associated With Immune Infiltration in Prostate Cancer

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Cancer progression and tumor hypercoagulability: a platelet perspective

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O-GlcNAcylation: Crosstalk between Hemostasis, Inflammation, and Cancer

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Circulating Proteins Associated with Response and Resistance to Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer

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Unlocking the intricacies: Exploring the complex interplay between platelets and ovarian cancer

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Bioengineering Platelets Presenting PD‐L1, Galectin‐9 and BTLA to Ameliorate Type 1 Diabetes

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Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges

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Prognostic Value of Platelet Distribution Width and Mean Platelet Volume in Patients with Laryngeal Cancer

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Relationship between tumorigenesis, metastasis, immune evasion, and chemoresistance in osteosarcoma therapy

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Reversibly size-switchable polyion complex micelles for antiangiogenic cancer therapy

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Coagulation-Targeted TGF-β Signaling Pathway Inhibitor Nanomedicine for Inhibiting the Growth and Lung Metastasis of Breast Cancer

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Unveiling the “Dark Matter” of platelet involvement in tumor microenvironment

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A biomaterial-based platform of pancreatic cancer reveals kallikrein-related peptidase 6 (KLK6) as a mediator of neutrophil recruitment and immunosuppression

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Key platelet genes play important roles in predicting the prognosis of sepsis

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Transforming Growth Factors in Venous Thrombus Formation and Resolution

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FVIIa-PAR2 signaling facilitates immune escape by reducing phagocytic potential of macrophages in breast cancer

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Adjuvant chemotherapy for lymph node positive esophageal squamous cell cancer: The prediction role of low mean platelet volume

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Tumor-educated platelets as liquid biopsy: Uncovering the mechanisms of cancer progression

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Tumor-platelet cross talk in cancer: mechanisms, thrombotic risk, and translational opportunities

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A novel immune-related gene signature for diagnosis and potential immunotherapy of microsatellite stable endometrial carcinoma

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Integrative Quantitative Analysis of Platelet Proteome and Site-Specific Glycoproteome Reveals Diagnostic Potential of Platelet Glycoproteins for Liver Cancer

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An artificial-enzyme-equipped immunoregulator blocks platelet-mediated breast cancer hematogenous metastasis

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GARP Regulates the Immune Capacity of a Human Autologous Platelet Concentrate

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Tregs and Platelets Play Synergistic Roles in Tumor Immune Escape and Inflammatory Diseases

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Lentinan Alleviated PM2.5 Exposure-Induced Epithelial–Mesenchymal Transition in Pulmonary Epithelial Cells by Inhibiting the GARP/TGF-β/Smad Pathway

Wang, Z., Xu, S., Bian, B., Hu, Z., Wu, F., Zhao, S., Wang, X., Wang, L., & Ma, T. (2025) · Toxics · doi:10.3390/toxics13030166 · Cited by 4 · see citing works

Coagulation proteases modulate nucleic acid uptake and cGAS-STING-IFN induction in the tumor microenvironment

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TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

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Drug-drug interactions in anticoagulant therapy: a focus on oncology patients

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Platelets in the tumor microenvironment: potential mediators of immune exclusion and resistance to immune checkpoint inhibitor therapy

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Synergistic effects of anticoagulants and platelet aggregation inhibitors with immune checkpoint inhibitors in cancer therapy: a comprehensive review of preclinical and clinical evidence

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Characterization of Platelet Function-Related Gene Predicting Survival and Immunotherapy Efficacy in Gastric Cancer

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Small but mighty: Platelets as multifunctional architects of tumor metastasis and immune regulation

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New insight into GARP striking role in cancer progression: application for cancer therapy

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ADNP is associated with immune infiltration and radiosensitivity in hepatocellular carcinoma for predicting the prognosis

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Associations Between Immune-Related Venous Thromboembolism and Efficacy of Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis

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Anticoagulation for the treatment of immune checkpoint inhibitor–associated venous thromboembolism

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Spatial Distribution of Non-Immune Cells Expressing Glycoprotein A Repetitions Predominant in Human and Murine Metastatic Lymph Nodes

Rouaud, L., Baudin, L., Gautier‐Isola, M., Meerbeeck, P. V., Feyereisen, É., Blacher, S., van Baren, N., Kridelka, F., Lucas, S., & Noël, A. (2023) · Cancers · doi:10.3390/cancers15235621 · Cited by 3 · see citing works

Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP for LTGF-β activation

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GARP-TGFβ Axis on Activated Platelets Supports Tumor Progression

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Platelets subvert T cell immunity against cancer via GARP-TGFβ axis

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Immunomodulatory role of thrombin in cancer progression

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Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer

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