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A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components
Open accessAbstract
YAP and FOXM1 are mediators of EGFR inhibitor resistance, and spindle proteins are therapeutic targets for this multidrug-resistant phenotype.
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“Particularly, YAP/TAZ plays a crucial role in the intrinsic and acquired resistance to inhibitors targeting RTK/MAPK pathway (24, 28–32).”
From YAP/TAZ mediates resistance to KRAS inhibitors through inhibiting proapoptosis and activating the SLC7A5/mTOR axis (2024) · cites this paper as [28]
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“accumulating evidence suggests that the dysregulation of the Hippo-YAP/TAZ pathway serves as a central resistance mechanism in multiple therapies, particularly in the intrinsic and acquired resistance to RTK, RAF, or MEK inhibitors (24, 28, 29).”
From YAP/TAZ mediates resistance to KRAS inhibitors through inhibiting proapoptosis and activating the SLC7A5/mTOR axis (2024) · cites this paper as [28]
Experimental — accuracy not yet measuredIn the citing paper
“Nilsson et al. identified activation of a YAP/FOXM1 axis in EMT EGFR TKI-resistant models [91]. This was associated with dysregulation of spindle assembly checkpoint (SAC) proteins, including polo-like kinase 1, aurora kinases, and kinesin spindle protein, and rendered cells vulnerable to SAC inhibitors.”
From Emerging Insights into Targeted Therapy-Tolerant Persister Cells in Cancer (2021) · cites this paper as [91]
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Cites
The Sequence Alignment/Map format and SAMtools
Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., Durbin, R., & 1000 Genome Project Data Processing Subgroup (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp352 · Cited by 62,041
Fast and accurate short read alignment with Burrows-Wheeler transform
Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
Wang, K., Li, M., & Hakonarson, H. H. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq603 · Cited by 14,724
Fast and accurate long-read alignment with Burrows-Wheeler transform.
Li, H., & Durbin, R. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp698 · Cited by 12,063
Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
Mok, T. S., Wu, Y.-L., Thongprasert, S., Yang, C.-H., Chu, D.-T., Saijo, N., Sunpaweravong, P., Han, B., Margono, B., Ichinose, Y., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810699 · Cited by 8,261
Comprehensive molecular profiling of lung adenocarcinoma
The Cancer Genome Atlas Research Network (2014) · Nature · doi:10.1038/nature13385 · Cited by 5,732
Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR
Maemondo, M., Inoue, A., Kobayashi, K., Sugawara, S., Oizumi, S., Isobe, H., Gemma, A., Harada, M., Yoshizawa, H., Kinoshita, I., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0909530 · Cited by 5,525
Osimertinib in Untreated EGFR -Mutated Advanced Non–Small-Cell Lung Cancer
Soria, J.-C., Ohe, Y., Vansteenkiste, J., Reungwetwattana, T., Chewaskulyong, B., Lee, K. H., Dechaphunkul, A., Imamura, F., Nogami, N., Kurata, T., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1713137 · Cited by 5,508
Rosell, R., Carcereny, E., Gervais, R., Vergnenegre, A., Massuti, B., Felip, E., Palmero, R., Garcia-Gomez, R., Pallares, C., Sanchez, J. M., et al. (2012) · The Lancet Oncology · doi:10.1016/s1470-2045(11)70393-x · Cited by 5,489
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencingPreprint
Koboldt, D. C., Zhang, Q., Larson, D. E., Shen, D., McLellan, M. D., Lin, L., Miller, C. A., Mardis, E. R., Ding, L., & Wilson, R. K. (2012) · Genome Research · doi:10.1101/gr.129684.111 · Cited by 4,954
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
Engelman, J. A., Zejnullahu, K., Mitsudomi, T., Song, Y., Hyland, C., Park, J. O., Lindeman, N., Gale, C.-M., Zhao, X., Christensen, J., et al. (2007) · Science · doi:10.1126/science.1141478 · Cited by 4,496
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
Kobayashi, S., Boggon, T. J., Dayaram, T., Jänne, P. A., Kocher, O., Meyerson, M., Johnson, B. E., Eck, M. J., Tenen, D. G., & Halmos, B. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa044238 · Cited by 3,964
Pao, W., Miller, V. A., Politi, K. A., Riely, G. J., Somwar, R., Zakowski, M. F., Kris, M. G., & Varmus, H. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020073 · Cited by 3,527 · cited 1×
“The most frequently observed resistance mechanisms are the emergence of secondary T790M mutations and MET amplification (8, 14, 24, 45).”
BackgroundGenotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
Sequist, L. V., Waltman, B. A., Dias-Santagata, D., Digumarthy, S., Turke, A. B., Fidias, P., Bergethon, K., Shaw, A. T., Gettinger, S., Cosper, A. K., et al. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002003 · Cited by 3,499
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
Mok, T. S., Wu, Y.-L., Ahn, M.-J., Garassino, M. C., Kim, H. R., Ramalingam, S. S., Shepherd, F. A., He, Y., Akamatsu, H., Theelen, W. S. M. E., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1612674 · Cited by 3,379
The spindle-assembly checkpoint in space and time
Musacchio, A., & Salmon, E. D. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2163 · Cited by 2,227
Bean, J., Brennan, C., Shih, J.-Y., Riely, G., Viale, A., Wang, L., Chitale, D., Motoi, N., Szoke, J., Broderick, S., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710370104 · Cited by 1,598
Liu-Chittenden, Y., Huang, B., Shim, J. S., Chen, Q., Lee, S.-J., Anders, R. A., Liu, J. O., & Pan, D. (2012) · Genes & Development · doi:10.1101/gad.192856.112 · Cited by 1,452
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
Cordenonsi, M., Zanconato, F., Azzolin, L., Forcato, M., Rosato, A., Frasson, C., Inui, M., Montagner, M., Parenti, A. R., Poletti, A., et al. (2011) · Cell · doi:10.1016/j.cell.2011.09.048 · Cited by 1,381
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
Zhang, Z., Lee, J. C., Lin, L., Olivas, V., Au, V., LaFramboise, T., Abdel-Rahman, M., Wang, X., Levine, A. D., Rho, J. K., et al. (2012) · Nature Genetics · doi:10.1038/ng.2330 · Cited by 1,224
Byers, L. A., Diao, L., Wang, J., Saintigny, P., Girard, L., Peyton, M., Shen, L., Fan, Y., Giri, U., Tumula, P. K., et al. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-1558 · Cited by 1,059
Self-citationChristiansen, J. J., & Rajasekaran, A. K. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0410 · Cited by 1,051
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
Nieto, M. A. (2013) · Science · doi:10.1126/science.1234850 · Cited by 991
Basu, S., Totty, N. F., Irwin, M. S., Sudol, M., & Downward, J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(02)00776-1 · Cited by 843
Sequist, L. V., Martins, R. G., Spigel, D., Grunberg, S. M., Spira, A., Jänne, P. A., Joshi, V. A., McCollum, D., Evans, T. L., Muzikansky, A., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.14.8494 · Cited by 820
Takezawa, K., Pirazzoli, V., Arcila, M. E., Nebhan, C. A., Song, X., de Stanchina, E., Ohashi, K., Janjigian, Y. Y., Spitzler, P. J., Melnick, M. A., et al. (2012) · Cancer Discovery · doi:10.1158/2159-8290.cd-12-0108 · Cited by 710
Oxnard, G. R., Hu, Y., Mileham, K. F., Husain, H., Costa, D. B., Tracy, P., Feeney, N., Sholl, L. M., Dahlberg, S. E., Redig, A. J., et al. (2018) · JAMA Oncology · doi:10.1001/jamaoncol.2018.2969 · Cited by 686
Thomson, S., Buck, E. A., Petti, F., Griffin, G., Brown, E., Ramnarine, N., Iwata, K. K., Gibson, N. W., & Haley, J. D. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1058 · Cited by 663
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
Niederst, M. J., Sequist, L. V., Poirier, J. T., Mermel, C. H., Lockerman, E. L., Garcia, A. R., Katayama, R., Costa, C., Ross, K. N., Moran, T., et al. (2015) · Nature Communications · doi:10.1038/ncomms7377 · Cited by 647
Pao, W. J., & Miller, V. A. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.07.799 · Cited by 637
Wang, I.-C., Chen, Y.-J., Hughes, D., Petrovic, V., Major, M. L., Park, H. J., Tan, Y., Ackerson, T., & Costa, R. H. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.24.10875-10894.2005 · Cited by 627
Aigner, K., Dampier, B., Descovich, L., Mikula, M., Sultan, A., Schreiber, M., Mikulits, W., Brabletz, T., Strand, D., Obrist, P., et al. (2007) · Oncogene · doi:10.1038/sj.onc.1210508 · Cited by 618
Gjerdrum, C., Tiron, C., Høiby, T., Stefansson, I., Haugen, H., Sandal, T., Collett, K., Li, S., McCormack, E., Gjertsen, B. T., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909333107 · Cited by 594
Yang, Z., Yang, N., Ou, Q., Xiang, Y., Jiang, T., Wu, X., Bao, H., Tong, X., Wang, X., Shao, Y. W., et al. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-2310 · Cited by 542
Sànchez‐Tilló, E., Lázaro, A., Torrent, R., Cuatrecasas, M., Vaquero, E. C., Castells, A., Engel, P., & Postigo, A. A. (2010) · Oncogene · doi:10.1038/onc.2010.102 · Cited by 526
Kurppa, K. J., Liu, Y., To, C., Zhang, T., Fan, M., Vajdi, A., Knelson, E. H., Xie, Y., Lim, K., Cejas, P., et al. (2020) · Cancer Cell · doi:10.1016/j.ccell.2019.12.006 · Cited by 475
Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways
Arbiser, J. L., Moses, M. A., Fernández, C. A., Ghiso, N., Cao, Y., Klauber, N., Frank, D. A., Brownlee, M., Flynn, E. A., Parangi, S., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.3.861 · Cited by 469
Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor–Resistant Disease
Ohashi, K., Maruvka, Y. E., Michor, F., & Pao, W. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.43.3912 · Cited by 467
Sànchez‐Tilló, E., de Barrios, O., Siles, L., Cuatrecasas, M., Castells, A., & Postigo, A. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1108977108 · Cited by 458
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
McDonald, O. G., Wu, H., Timp, W., Doi, A., & Feinberg, A. P. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2084 · Cited by 398
Le, X., Puri, S., Negrao, M. V., Nilsson, M. B., Robichaux, J., Boyle, T., Hicks, J. K., Lovinger, K. L., Roarty, E., Rinsurongkawong, W., et al. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-18-1542 · Cited by 387
Self-citationShah, K. N., Bhatt, R., Rotow, J., Rohrberg, J., Olivas, V., Wang, V. E., Hemmati, G., Martins, M. M., Maynard, A., Kuhn, J., et al. (2019) · Nature Medicine · doi:10.1038/s41591-018-0264-7 · Cited by 286
Mizuno, T., Murakami, H., Fujii, M., Ishiguro, F., Tanaka, I., Kondo, Y., Akatsuka, S., Toyokuni, S., Yokoi, K., Osada, H., et al. (2012) · Oncogene · doi:10.1038/onc.2012.5 · Cited by 278
Frederick, B. A., Helfrich, B. A., Coldren, C. D., Zheng, D., Chan, D., Bunn, P. A., & Raben, D. (2007) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-07-0138 · Cited by 270
Aurora kinase inhibitors: Progress towards the clinic
Kollareddy, M., Zheleva, D. I., Džubák, P., Brahmkshatriya, P. S., Lepšı́k, M., & Hajdúch, M. (2012) · Investigational New Drugs · doi:10.1007/s10637-012-9798-6 · Cited by 242
Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition
Gormally, M. V., Dexheimer, T. S., Marsico, G., Sanders, D. A., Lowe, C. E., Matak‐Vinković, D., Michael, S., Jadhav, A., Rai, G., Maloney, D. J., et al. (2014) · Nature Communications · doi:10.1038/ncomms6165 · Cited by 223
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo
Ashton, S. E., Song, Y. H., Nolan, J., Cadogan, E. B., Murray, J. A. H., Odedra, R., Foster, J. R., Hall, P. A., Low, S. C., Taylor, P., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aad2355 · Cited by 218
Suda, K., Murakami, I., Katayama, T., Tomizawa, K., Osada, H., Sekido, Y., Maehara, Y., Yatabe, Y., & Mitsudomi, T. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-1371 · Cited by 206
Song, S., Xie, M., Scott, A. W., Jin, J., Ma, L., Dong, X., Skinner, H. D., Johnson, R. L., Ding, S., & Ajani, J. A. (2017) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-17-0560 · Cited by 205
Chung, J.-H., Rho, J. K., Xu, X., Lee, J. S., Yoon, H. I., Lee, C. T., Choi, Y. J., Kim, H.-R., Kim, C. H., & Lee, J. C. (2010) · Lung Cancer · doi:10.1016/j.lungcan.2010.11.011 · Cited by 186
Epithelial-mesenchymal transition in EGFR-TKI acquired resistant lung adenocarcinoma.
Uramoto, H., Iwata, T., Onitsuka, T., Shimokawa, H., Hanagiri, T., & Oyama, T. (2010) · PubMed · Cited by 168
Nilsson, M. B., Sun, H., Diao, L., Tong, P., Liu, D., Li, L., Fan, Y., Poteete, A., Lim, S.-O., Howells, K., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aao4307 · Cited by 146
Self-citationChiu, W., Huang, Y.-F., Tsai, H.-Y., Chen, C., Chang, C.-H., Huang, S.-C., Hsu, K., & Chou, C.-Y. (2014) · Oncotarget · doi:10.18632/oncotarget.2957 · Cited by 144
AURKB as a target in non-small cell lung cancer with acquired resistance to anti-EGFR therapy
Bertrán-Alamillo, J., Cattan, V., Schoumacher, M., Codony‐Servat, J., Giménez-Capitán, A. A., Cantero, F., Burbridge, M. F., Rodríguez, S., Teixidó, C., Roman, R. A., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09734-5 · Cited by 139
FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair
Park, Y., Jung, S. Y., Jennings, N. B., Rodriguez‐Aguayo, C., Peng, G., Lee, S.-R., Kim, S. B., Kim, K., Leem, S.-H., Lin, S., et al. (2012) · Carcinogenesis · doi:10.1093/carcin/bgs167 · Cited by 135
YAP promotes erlotinib resistance in human non-small cell lung cancer cells
Hsu, P., You, B., Yang, Y., Zhang, W., Wang, Y., Xu, Z., Dai, Y., Liu, S., Yang, C., Li, H., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.10458 · Cited by 121
Reciprocal Regulation of c-Src and STAT3 in Non-Small Cell Lung Cancer
Byers, L. A., Sen, B., Saigal, B., Diao, L., Wang, J., Nanjundan, M., Cascone, T., Mills, G. B., Heymach, J. V., & Johnson, F. M. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0767 · Cited by 120
Self-citationYAP-Dependent AXL Overexpression Mediates Resistance to EGFR Inhibitors in NSCLC
Ghiso, E., Migliore, C., Ciciriello, V., Morando, E., Petrelli, A., Corso, S., Luca, E. D., Gatti, G., Volante, M., & Giordano, S. (2017) · Neoplasia · doi:10.1016/j.neo.2017.10.003 · Cited by 101
Yoshida, T., Song, L., Bai, Y., Kinose, F., Li, J., Ohaegbulam, K. C., Muñoz-Antonia, T., Qu, X., Eschrich, S. A., Uramoto, H., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147344 · Cited by 96
A genetic cell context-dependent role for ZEB1 in lung cancer
Zhang, T., Guo, L., Creighton, C. J., Lü, Q., Gibbons, D. L., Yi, E. S., Deng, B., Molina, J. R., Sun, Z., Yang, P., et al. (2016) · Nature Communications · doi:10.1038/ncomms12231 · Cited by 73
Self-citationTian, L., Zhao, Z., Xie, L., & Zhu, J. (2017) · Oncotarget · doi:10.18632/oncotarget.23513 · Cited by 71
Nanjundan, M., Byers, L. A., Carey, M. S., Siwak, D. R., Raso, M. G., Diao, L., Wang, J., Coombes, K. R., Roth, J. A., Mills, G. B., et al. (2010) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e3181f2a266 · Cited by 68
Self-citationEnhanced YAP expression leads to EGFR TKI resistance in lung adenocarcinomas
Lee, T., Tseng, Y.-C., Nguyễn, P. A., Li, Y., Ho, C., & Wu, C.-W. (2018) · Scientific Reports · doi:10.1038/s41598-017-18527-z · Cited by 60
Lin, S. H., Wang, J., Saintigny, P., Wu, C.-C., Giri, U. P., Zhang, J., Menju, T., Diao, L., Byers, L. A., Weinstein, J. N., et al. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-1079 · Cited by 54
Self-citationFan, Q., Cai, Q., & Xu, Y. (2015) · Oncotarget · doi:10.18632/oncotarget.4280 · Cited by 46
Oxnard, G. R., Cantarini, M., Frewer, P., Hawkins, G., Peters, J., Howarth, P., Ahmed, G. F., Sahota, T., Hartmaier, R. J., Li-Sucholeiki, X., et al. (2019) · Journal of Clinical Oncology · doi:10.1200/jco.2019.37.15_suppl.tps9119 · Cited by 37
Osimertinib in EGFR T790M–Positive Lung Cancer
Mok, T. S., Wu, Y.-L., & Papadimitrakopoulou, V. A. (2017) · New England Journal of Medicine · doi:10.1056/nejmc1703339 · Cited by 35
Nie, K., Jiang, H., Zhang, C., Geng, C., Xu, X., Zhang, L., Zhang, H., Zhang, Z., Lan, K., & Ji, Y. (2018) · BioMed Research International · doi:10.1155/2018/9010353 · Cited by 35
Cho, J.-H., Oh, A.-Y., Park, S., Kang, S., Yoon, M.-H., Woo, T.-G., Hong, S.-D., Hwang, J., Ha, N., Lee, H., et al. (2018) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-17-1210 · Cited by 34
FOXM1 Regulated by ERK Pathway MediatesTGF-1-Induced EMT in NSCLC
Kong, F., Zhu, Y., Yuan, H.-H., Wang, J., Zhao, M., Gong, X., Liu, F., Zhang, W., Wang, C., & Jiang, B. (2014) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504014x14078436004987 · Cited by 33
Self-citationWang, Y., Singh, R., Wang, L., Nilsson, M. B., Goonatilake, R., Tong, P., Li, L., Giri, U. P., Villalobos, P. A., Mino, B., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.10332 · Cited by 25
Self-citationZheng, L., Chen, L., Liao, X., Xu, Z., Chen, Z., & Sun, J. (2018) · BMC Cancer · doi:10.1186/s12885-018-4991-4 · Cited by 8
Cheng, Y., Zhou, J., Lü, S., Zhang, Y., Zhao, J., Pan, H., Chen, Y., Chian, C., Bruns, R., Johne, A., et al. (2018) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2018.10.024 · Cited by 2
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Metadata
- Authors
- Nilsson, M. B., Sun, H., Robichaux, J., Pfeifer, M., McDermott, U., Travers, J., Diao, L., Xi, Y., Tong, P., Shen, L., Hofstad, M., Kawakami, M., Le, X., Liu, X., Fan, Y., Poteete, A., Hu, L., Negrao, M. V., Tran, H., Dmitrovsky, E., Peng, D., Gibbons, D. L., Wang, J., & Heymach, J. V.
- Affiliations
- The University of Texas MD Anderson Cancer Center (US)
- AstraZeneca (United Kingdom) (GB)
- Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
- Corresponding author
- Heymach, John V.
- ORCID
- Nilsson, Monique B.
- Sun, Huiying
- Robichaux, Jacqulyne
- Pfeifer, Matthias
- McDermott, Ultan
- Travers, Jon
- Diao, Lixia
- Xi, Yuanxin
- Tong, Pan
- Shen, Li
- Hofstad, Mia
- Kawakami, Masanori
- Le, Xiuning
- Liu, Xi
- Fan, Youhong
- Poteete, Alissa
- Hu, Limei
- Negrao, Marcelo V.
- Tran, Hai
- Dmitrovsky, Ethan
- Peng, David
- Gibbons, Don L.
- Wang, Jing
- Heymach, John V.
- Venue
- Science Translational Medicine
- Published
- 2020-09-02
- Volume
- 12
- Issue
- 559
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC8269000
- OpenAlex
- W3082143929
- Cited by
- 177
- References
- 74
- Citations by year
- 2026: 15 · 2025: 34 · 2024: 29 · 2023: 40 · 2022: 31 · 2021: 26 · 2020: 2
- FWCI
- 14.23
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (Lung SPORE grant P50 CA070907, NIH CCSG (CA016672), CA016672, 1R01 CA190628)
- National Cancer Institute (HHSN261200800001E)
- LUNGevity Foundation
- University of Texas MD Anderson Cancer Center (Lung Cancer Moon Shot Program)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Treatments and Mutations
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Hippo pathway signaling and YAP/TAZ
- Health Sciences › Medicine › Oncology › HER2/EGFR in Cancer Research
- Keywords
- epithelial-mesenchymal transition, EGFR tyrosine kinase inhibitor resistance, spindle assembly checkpoint, multidrug resistance, therapeutic vulnerabilities, non-small cell lung cancer, clinical outcomes
- MeSH terms
- Forkhead Box Protein M1, Antineoplastic Agents, Carcinoma, Non-Small-Cell Lung, Humans, Lung Neoplasms, Drug Resistance, Neoplasm, Proteomics, Cell Line, Tumor, Protein Kinase Inhibitors, Epithelial-Mesenchymal Transition, M Phase Cell Cycle Checkpoints, ErbB Receptors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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