The DOI matches its Crossref record; 73 of the 74 references it cites were found in a registry or an index.
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes
Open accessAbstract
A nanofibrous cell encapsulation device containing rodent/human islets or human stem cell–derived β cells treats diabetes in rodents.
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“Similarly, mice transplant outcomes for SC-islets within a microencapsulation device were more favorable in the intraperitoneal cavity than in the subcutaneous space due to a much lower fibrotic response.102”
From Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes (2023) · cites this paper as [102]
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Cites
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Hydrogels for biomedical applications
Hoffman, A. S. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00239-3 · Cited by 4,864
Hydrogels for biomedical applications
Hoffman, A. S. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.010 · Cited by 3,396
Generation of Functional Human Pancreatic β Cells In Vitro
Pagliuca, F. W., Millman, J. R., Gürtler, M., Segel, M., Van Dervort, A., Ryu, J. H., Peterson, Q. P., Greiner, D., & Melton, D. A. (2014) · Cell · doi:10.1016/j.cell.2014.09.040 · Cited by 2,025
Self-citationInternational trial of the Edmonton protocol for islet transplantation
Shapiro, A. M. J., Ricordi, C., Hering, B. J., Auchincloss, H., Lindblad, R., Robertson, R. P., Secchi, A., Brendel, M. D., Berney, T., Brennan, D. C., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa061267 · Cited by 1,942
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Wen, L., Ley, R. E., Volchkov, P. Y., Stranges, P. B., Avanesyan, L., Stonebraker, A. C., Hu, C., Wong, F. S., Szot, G. L., Bluestone, J. A., et al. (2008) · Nature · doi:10.1038/nature07336 · Cited by 1,921
Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
Rezania, A., Bruin, J. E., Arora, P., Rubin, A., Batushansky, I., Asadi, A., O'Dwyer, S., Quiskamp, N., Mojibian, M., Albrecht, T., et al. (2014) · Nature Biotechnology · doi:10.1038/nbt.3033 · Cited by 1,575
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Self-citationInactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
Niu, D., Wei, H.-J., Lin, L., George, H., Wang, T., Lee, I.-H., Zhao, H.-Y., Wang, Y., Kan, Y., Shrock, E., et al. (2017) · Science · doi:10.1126/science.aan4187 · Cited by 717
Self-citationVegas, A. J., Veiseh, O., Gürtler, M., Millman, J. R., Pagliuca, F. W., Bader, A. R., Doloff, J. C., Li, J., Chen, M., Olejnik, K., et al. (2016) · Nature Medicine · doi:10.1038/nm.4030 · Cited by 710
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Items 101–119 of 119
Schäfer‐Korting, M. (2023) · Handbook of experimental pharmacology · doi:10.1007/164_2023_696 · Cited by 1
Islet Macroencapsulation: Strategies to Boost Islet Graft Oxygenation
Ludwig, B., Heller, C., Sarangova, V., & Welzel, P. B. (2023) · Springer eBooks · doi:10.1007/978-3-031-41943-0_12 · Cited by 1
Scaffolds for Encapsulation of Stem Cell-Derived β Cells
de Vries, R. H. W., & van Apeldoorn, A. A. (2023) · Springer eBooks · doi:10.1007/978-3-031-41943-0_7 · Cited by 2
Targeting clonal mutations with synthetic microbes
Renteln, M. (2024) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2024.104572 · Cited by 5
Subcutaneous Implantation of Open Microwell Islet Delivery Devices in Pigs
Tol, M. C., de Vries, R. H. W., Engelse, M. A., Carlotti, F., van Apeldoorn, A. A., de Koning, E. J. P., & Huurman, V. A. L. (2024) · Surgical Innovation · doi:10.1177/15533506241306491 · Cited by 1
Editorial: Bioengineered gene and cell therapy for treating cardiovascular diseases
Wang, K., Liu, X., Lian, X. L., Bao, X., & Li, K. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1250175 · Cited by 1
Self-citationTransplantation of Pancreatic Islets
Rao, J. S., Bellin, M. D., & Hering, B. J. (2023) · Wiley eBooks · doi:10.1002/9781119876007.ch166 · Cited by 1
Xenotransplantation von Pankreasinseln – aktueller Stand
Wolf, E., Kemter, E., Buerck, L. W., & Seißler, J. (2022) · Die Diabetologie · doi:10.1007/s11428-022-00949-7
Use of Immunomodulatory Biomaterials in Diabetes Therapy
Kim, B., & Mukherjee, S. (2024) · Synthesis lectures on biomedical engineering · doi:10.1007/978-3-031-50844-8_3
3D Organoids of Mesenchymal Stromal and Pancreatic Islet Cells
Westenfelder, C. S., & Gooch, A. M. (2023) · Springer eBooks · doi:10.1007/978-3-031-41943-0_9
An Autoclavable and Transparent Thermal Cutter for Reliably Sealing Wet Nanofibrous Membranes
Fang, C., Gu, Y., Shi, H., Hu, J. F., Wang, Y., Pan, M., Feng, J., Li, Y., Ma, Y., Wang, T., et al. (2024) · Nano Letters · doi:10.1021/acs.nanolett.4c02096
Self-citationLee, M., Wang, B., Wang, K., Okada, K., Flanders, J. A., Barutis, A., Melero‐Martin, J. M., & Ma, M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.03.730028
Self-citationKasinathan, G. N., Pondugala, P. K., Ruhela, A., Reddy, N., Rao, G. V., Sharma, C. S., Sasikala, M., & Rath, S. N. (2026) · RSC Advances · doi:10.1039/d6ra03535c
Li, H., Long, P., Qin, W., Chen, X., Liao, C., Shi, H., Liu, Y., & Gao, L. (2026) · ACS Materials Letters · doi:10.1021/acsmaterialslett.6c00481
Odorico, J. S., Citro, A., de Koning, E. J. P., Kay, T., Latres, E., Millman, J. R., Nostro, M. C., Piemonti, L., Rickels, M. R., Russ, H. A., et al. (2026) · Transplantation · doi:10.1097/tp.0000000000005783
Self-citationCitro, A., & Piemonti, L. (2026) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2026.1943061
Metadata
- Authors
- Wang, X., Maxwell, K. G., Wang, K., Bowers, D. T., Flanders, J. A., Liu, W., Wang, L.-H., Liu, Q., Liu, C., Naji, A., Wang, Y., Wang, B., Chen, J., Ernst, A. U., Melero-Martin, J. M., Millman, J. R., & Ma, M.
- Affiliations
- Cornell University (US)
- Washington University in St. Louis (US)
- Boston Children's Hospital (US)
- Hospital of the University of Pennsylvania (US)
- University of Virginia (US)
- Department of Cardiac Surgery, Boston Children’s Hospital, Boston, MA 02115, USA.
- Corresponding author
- Millman, Jeffrey R.
- Ma, Minglin
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2021-06-02
- Volume
- 13
- Issue
- 596
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC8563008
- OpenAlex
- W3164081747
- Cited by
- 119
- References
- 74
- Citations by year
- 2026: 10 · 2025: 14 · 2024: 33 · 2023: 25 · 2022: 25 · 2021: 12
- FWCI
- 22.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (1R01DK105967-01A1, 5R01DK114233, T32DK108742)
- National Institute of Diabetes and Digestive and Kidney Diseases (10028044)
- Hartwell Foundation
- JDRF (5-CDA-2017-391-A-N, 2-SRA-2018-472-S-B)
- Novo Nordisk Company
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pancreatic function and diabetes
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Keywords
- type 1 diabetes, stem cell-derived beta cells, cell encapsulation, nanofibrous scaffolds, electrospinning, islet transplantation, xenotransplantation, peritoneal implantation, xenogeneic immune response, diabetes reversal
- MeSH terms
- Animals, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Dogs, Insulin, Islets of Langerhans Transplantation, Insulin-Secreting Cells, Mice, Nanofibers, Insulins
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