The DOI matches its Crossref record.
Amphotericin B: current understanding of mechanisms of action
Open accessAbstract
This minireview describes the problems associated with the use of Amphotericin B and what is known about the mechanism(s) of its action. The efforts to design a more efficient vehicle for AmB are summarized in the following minireview (8)
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Citations
Cited by
Groll, A. H., Piscitelli, S. C., & Walsh, T. J. (1998) · Advances in pharmacology · doi:10.1016/s1054-3589(08)60129-5 · Cited by 377
Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B
Vincent, B. M., Lancaster, A. K., Scherz-Shouval, R., Whitesell, L., & Lindquist, S. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001692 · Cited by 322
“Its potent fungicidal activity derives from its ability to selectively bind the major sterol of fungal membranes, ergosterol [7,8].”
BackgroundLiu, T. T., Lee, R. E. B., Barker, K. S., Lee, R. E., Wei, L., Homayouni, R., & Rogers, P. D. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.6.2226-2236.2005 · Cited by 313
It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug
Mesa-Arango, A. C., Scorzoni, L., & Zaragoza, O. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00286 · Cited by 311
Amphotericin B-induced nephrotoxicity: a review.
Fanos, V., & Cataldi, L. (2000) · Journal of Chemotherapy · doi:10.1179/joc.2000.12.6.463 · Cited by 259
Reactive Oxygen Species-Inducing Antifungal Agents and Their Activity Against Fungal Biofilms
Delattin, N., Cammue, B. P., & Thevissen, K. (2014) · Future Medicinal Chemistry · doi:10.4155/fmc.13.189 · Cited by 189
Efficacy of oral cochleate-amphotericin B in a mouse model of systemic candidiasis
Santangelo, R., Paderu, P., Delmas, G., Chen, Z.-W., Mannino, R., Zarif, L., & Perlin, D. S. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.9.2356-2360.2000 · Cited by 150
Jensen-Pergakes, K. L., Kennedy, M. A., Lees, N. D., Barbuch, R., Koegel, C., & Bard, M. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.5.1160 · Cited by 121
Alteration of Cell Wall Composition Leads to Amphotericin B Resistance in Aspergillus flavus
Seo, K., Akiyoshi, H., & Ohnishi, Y. (1999) · Microbiology and Immunology · doi:10.1111/j.1348-0421.1999.tb01231.x · Cited by 88
Mesa-Arango, A. C., Rueda, C., Román, E., Quintin, J., Terrón, M. C., Luque, D., Netea, M. G., Pla, J., & Zaragoza, O. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02681-15 · Cited by 86
Satish, S., Jiménez-Ortigosa, C., Zhao, Y., Lee, M. H., Dolgov, E., Krüger, T., Park, S., Denning, D. W., Kniemeyer, O., Brakhage, A. A., et al. (2019) · mBio · doi:10.1128/mbio.00779-19 · Cited by 64
Jia, N., Arthington-Skaggs, B., Lee, W., Pierson, C. A., Lees, N. D., Eckstein, J., Barbuch, R., & Bard, M. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.4.947-957.2002 · Cited by 61
Zhu, C., Liao, B., Ye, X., Zhou, Y., Chen, X., Liao, M., Cheng, L., Zhou, X., & Ren, B. (2021) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2021.106394 · Cited by 60
We can do better: a fresh look at echinocandin dosing
Bader, J. C., Bhavnani, S. M., Andes, D. R., & Ambrose, P. G. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx448 · Cited by 46
Enhancement of Amphotericin B Activity Against Candida albicans by Superoxide Radical
Okamoto, Y., Aoki, S., & Mataga, I. (2004) · Mycopathologia · doi:10.1023/b:myco.0000038430.20669.80 · Cited by 35
Metadata
- Authors
- Brajtburg, J., Powderly, W. G., Kobayashi, G. S., & Medoff, G.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1990-02
- Volume
- 34
- Issue
- 2
- Pages
- 183-188
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W2168781246
- Cited by
- 504
- References
- 0
- FWCI
- 13.69
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
