Possible Environmental Origin of Resistance of Aspergillus fumigatus to Medical Triazoles

National Committee for Clinical Laboratory Standards

Bruck, E. (1980) · PEDIATRICS · doi:10.1542/peds.65.1.187 · Cited by 14,736

Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes

Glass, N. L., & Donaldson, G. C. (1995) · Applied and Environmental Microbiology · doi:10.1128/aem.61.4.1323-1330.1995 · Cited by 4,765

Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism

Snelders, E., van der Lee, H. A. L., Kuijpers, J., Rijs, A. J. M. M., Varga, J., Samson, R. A., Mellado, E., Donders, A. R. T., Melchers, W. J. G., & Verweij, P. E. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050219 · Cited by 726

A New Aspergillus fumigatus Resistance Mechanism Conferring In Vitro Cross-Resistance to Azole Antifungals Involves a Combination of cyp51A Alterations

Mellado, E., Garcia-Effron, G., Alcázar-Fuoli, L., Melchers, W. J. G., Verweij, P. E., Cuenca-Estrella, M., & Rodríguez-Tudela, J. L. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01092-06 · Cited by 490

Multiple-Triazole–Resistant Aspergillosis

Verweij, P. E., Mellado, E., & Melchers, W. J. G. (2007) · New England Journal of Medicine · doi:10.1056/nejmc061720 · Cited by 380

Evolution of antifungal-drug resistance: mechanisms and pathogen fitness

Anderson, J. B. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1179 · Cited by 375

A Point Mutation in the 14α-Sterol Demethylase Gene cyp51A Contributes to Itraconazole Resistance in Aspergillus fumigatus

Diaz-Guerra, T. M., Mellado, E., Cuenca-Estrella, M., & Rodriguez-Tudela, J. L. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.3.1120-1124.2003 · Cited by 281

Polyphasic taxonomy of Aspergillus section Fumigati and its teleomorph Neosartorya

Samson, R. A., Hong, S., Peterson, S. W., Frisvad, J. C., & Varga, J. (2007) · Studies in Mycology · doi:10.3114/sim.2007.59.14 · Cited by 259

Use of a Novel Panel of Nine Short Tandem Repeats for Exact and High-Resolution Fingerprinting of Aspergillus fumigatus Isolates

de Valk, H. A., Meis, J. F. G. M., Curfs-Breuker, I., Muehlethaler, K., Mouton, J. W., & Klaassen, C. H. W. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.8.4112-4120.2005 · Cited by 248

An Aspergillus fumigatus alkaline protease mutant constructed by gene disruption is deficient in extracellular elastase activity

Tang, C. M., Cohen, J., & Holden, D. W. (1992) · Molecular Microbiology · doi:10.1111/j.1365-2958.1992.tb00891.x · Cited by 149

Mechanisms of triazole resistance in Aspergillus fumigatus

Nywening, A. V., Rybak, J. M., Rogers, P. D., & Fortwendel, J. R. (2020) · Environmental Microbiology · doi:10.1111/1462-2920.15274 · Cited by 76

Comparison of Human and Soil Candida tropicalis Isolates with Reduced Susceptibility to Fluconazole

Yang, Y.-L., Lin, C.-C., Chang, T.-P., Lauderdale, T.-L. Y., Chen, H., Lee, C.-F., Hsieh, C.-W., Chen, P., & Lo, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034609 · Cited by 73

High prevalence of clinical and environmental triazole-resistant Aspergillus fumigatus in Iran: is it a challenging issue?

Nabili, M., Shokohi, T., Moazeni, M., Khodavaisy, S., Aliyali, M., Badiee, P., Zarrinfar, H., Hagen, F., & Badali, H. (2016) · Journal of Medical Microbiology · doi:10.1099/jmm.0.000255 · Cited by 74

Occurrence of triazole-resistant Aspergillus fumigatus with TR34/L98H mutations in outdoor and hospital environment in Kuwait

Ahmad, S., Khan, Z., Hagen, F., & Meis, J. F. G. M. (2014) · Environmental Research · doi:10.1016/j.envres.2014.05.009 · Cited by 72

Azole-resistant Aspergillus fumigatus in the environment of northern Italy, May 2011 to June 2012

Prigitano, A., Venier, V., Cogliati, M., Lorenzis, G. D., Esposto, M. C., & Tortorano, A. M. (2014) · Eurosurveillance · doi:10.2807/1560-7917.es2014.19.12.20747 · Cited by 79

Epidemiology and antifungal resistance in invasive aspergillosis according to primary disease - review of the literature

Mayr, A., & Lass‐Flörl, C. (2011) · European journal of medical research · doi:10.1186/2047-783x-16-4-153 · Cited by 71

A myosin5 dsRNA that reduces the fungicide resistance and pathogenicity of Fusarium asiaticum

Song, X., Gu, K., Duan, X., Xiao, X., Hou, Y., Duan, Y., Wang, J., & Zhou, M. (2018) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2018.07.004 · Cited by 70

Isolation of azole-resistant Aspergillus fumigatus from the environment in the south-eastern USA

Hurst, S. F., Berkow, E. L., Stevenson, K. L., Litvintseva, A. P., & Lockhart, S. R. (2017) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx168 · Cited by 66

First Description of Azole-Resistant Aspergillus fumigatus Due to TR 46 /Y121F/T289A Mutation in France

Lavergne, R., Morio, F., Favennec, L., Dominique, S., Meis, J. F. G. M., Gargala, G., Verweij, P. E., & Pape, P. L. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00127-15 · Cited by 69

Azole-resistant Aspergillus fumigatus: A global phenomenon originating in the environment?

Jeanvoine, A., Rocchi, S., Bellanger, A., Reboux, G., & Millon, L. (2019) · Médecine et Maladies Infectieuses · doi:10.1016/j.medmal.2019.07.014 · Cited by 73

Development of cross-resistance by Aspergillus fumigatus to clinical azoles following exposure to prochloraz, an agricultural azole

Faria‐Ramos, I., Farinha, S., Neves-Maia, J., Tavares, P. R., Miranda, I. M., Estevinho, L. M., Pina‐Vaz, C., & Rodrigues, A. G. (2014) · BMC Microbiology · doi:10.1186/1471-2180-14-155 · Cited by 68

Triazole fungicides and the selection of resistance to medical triazoles in the opportunistic mould Aspergillus fumigatus

Verweij, P. E., Kema, G. H., Zwaan, B., & Melchers, W. J. (2013) · Pest Management Science · doi:10.1002/ps.3390 · Cited by 67

Azole-Resistant Invasive Aspergillosis: Relationship to Agriculture

Stensvold, C. R., Jørgensen, L. N., & Arendrup, M. C. (2012) · Current Fungal Infection Reports · doi:10.1007/s12281-012-0097-7 · Cited by 75

Aspergillosis, Avian Species and the One Health Perspective: The Possible Importance of Birds in Azole Resistance

Melo, A. M., Stevens, D. A., Tell, L. A., Veríssimo, C., Sabino, R., & Xavier, M. O. (2020) · Microorganisms · doi:10.3390/microorganisms8122037 · Cited by 68

Emerging Fungal Threats to Plants and Animals Challenge Agriculture and Ecosystem Resilience

Fones, H. N., Fisher, M. C., & Gurr, S. J. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.funk-0027-2016 · Cited by 74

Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?

Alanio, A., Desnos‐Ollivier, M., Garcia‐Hermoso, D., & Bretagne, S. (2017) · Clinical Microbiology Reviews · doi:10.1128/cmr.00043-16 · Cited by 69

Azole-resistantAspergillus fumigatusin sawmills of Eastern France

Jeanvoine, A., Rocchi, S., Reboux, G., Morin‐Crini, N., Crini, G., & Millon, L. (2017) · Journal of Applied Microbiology · doi:10.1111/jam.13488 · Cited by 71

High Azole Resistance in Aspergillus fumigatus Isolates from Strawberry Fields, China, 2018

Chen, Y., Dong, F., Zhao, J., Fan, H. S., Qin, C., Li, R., Verweij, P. E., Zheng, Y., & Han, L. (2019) · Emerging infectious diseases · doi:10.3201/eid2601.190885 · Cited by 70

Elevated prevalence of azole resistant Aspergillus fumigatus in urban versus rural environments in the United Kingdom

Sewell, T. R., Zhang, Y., Brackin, A. P., Shelton, J. M. G., Rhodes, J., & Fisher, M. C. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00548-19 · Cited by 62

EPIDEMIOLOGY OF INVASIVE FUNGAL INFECTIONS IN THE MEDITERRANEAN AREA

Binder, U., & Lass‐Flörl, C. (2011) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2011.016 · Cited by 61

Antifungal azoles and azole resistance in the environment: current status and future perspectives—a review

Assress, H. A., Selvarajan, R., Nyoni, H. H., Mamba, B. B., & Msagati, T. A. M. (2021) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-021-09594-w · Cited by 69

Rapid Diagnosis of Azole-Resistant Aspergillosis by Direct PCR Using Tissue Specimens

van der Linden, J. W. M., Snelders, E., Arends, J. P., Daenen, S. M. G. J., Melchers, W. J. G., & Verweij, P. E. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.02221-09 · Cited by 60

Multicentre validation of 4-well azole agar plates as a screening method for detection of clinically relevant azole-resistant Aspergillus fumigatus

Arendrup, M. C., Verweij, P. E., Mouton, J. W., Lagrou, K., & Meletiadis, J. (2017) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx319 · Cited by 61

Azole Resistance of Environmental and Clinical Aspergillus fumigatus Isolates from Switzerland

Riat, A., Plojoux, J., Gindro, K., Schrenzel, J., & Sanglard, D. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02088-17 · Cited by 63

Evolution of cross-resistance to medical triazoles inAspergillus fumigatusthrough selection pressure of environmental fungicides

Zhang, J., van den Heuvel, J., Debets, A. J. M., Verweij, P. E., Melchers, W. J. G., Zwaan, B. J., & Schoustra, S. E. (2017) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2017.0635 · Cited by 59

Emergence of azole resistant Aspergillus fumigatus and One Health: time to implement environmental stewardship

Chowdhary, A., & Meis, J. F. G. M. (2018) · Environmental Microbiology · doi:10.1111/1462-2920.14055 · Cited by 64

In vitro–in vivo correlation of voriconazole resistance due to G448S mutation (cyp51A gene) in Aspergillus fumigatus

Krishnan Natesan, S., Wu, W., Cutright, J. L., & Chandrasekar, P. H. (2012) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2012.06.030 · Cited by 58

First determination of azole resistance in Aspergillus fumigatus strains carrying the TR34/L98H mutations in Turkey

Özmerdiven, G. E., Aksoy, S. A., Ener, B., Ağca, H., Cılo, B. D., Tunca, B., & Akalın, H. (2015) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2015.04.012 · Cited by 58

Insight into the Significance of Aspergillus fumigatus cyp51A Polymorphisms

Garcia‐Rubio, R., Alcázar‐Fuoli, L., Monteiro, M. C., Monzón, S., Cuesta, I., Peláez, T., & Mellado, E. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00241-18 · Cited by 61

Scientific Opinion on the maintenance of the list of QPS microorganisms intentionally added to food or feed (2009 update)

(BIOHAZ), E. P. O. B. H. (2009) · EFSA Journal · doi:10.2903/j.efsa.2009.1431 · Cited by 57

Does agricultural use of azole fungicides contribute to resistance in the human pathogen Aspergillus fumigatus ?

Hollomon, D. (2017) · Pest Management Science · doi:10.1002/ps.4607 · Cited by 57

Prevalence of Azole-Resistant Aspergillus fumigatus is Highly Associated with Azole Fungicide Residues in the Fields

Cao, D., Wang, F., Yu, S., Dong, S., Wu, R., Cui, N., Ren, J., Xu, T., Wang, S., Wang, M., et al. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.0c03958 · Cited by 57

Aspergillus fumigatus Strains with Mutations in the cyp51A Gene Do Not Always Show Phenotypic Resistance to Itraconazole, Voriconazole, or Posaconazole

Escribano, P., Recio, S., Peláez, T., Bouza, E., & Guinea, J. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01358-10 · Cited by 57

Invasive Fungal Infections in Patients with Hematological Malignancies: Emergence of Resistant Pathogens and New Antifungal Therapies

Gamaletsou, M. N., Walsh, T. J., & Sipsas, N. V. (2018) · Turkish Journal of Hematology · doi:10.4274/tjh.2018.0007 · Cited by 59

Aspergillus fumigatus harbouring the sole Y121F mutation shows decreased susceptibility to voriconazole but maintained susceptibility to itraconazole and posaconazole

Lescar, J., Meyer, I., Akshita, K., Srinivasaraghavan, K., Verma, C., Palous, M., Mazier, D., Datry, A., & Fekkar, A. (2014) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dku316 · Cited by 54

Extensive Genetic Diversity and Widespread Azole Resistance in Greenhouse Populations of Aspergillus fumigatus in Yunnan, China

Zhou, D., Korfanty, G. A., Mo, M., Wang, R., Li, X., Li, H., Li, S., Wu, J., Zhang, K., Zhang, Y., et al. (2021) · mSphere · doi:10.1128/msphere.00066-21 · Cited by 57

The Emerging Threat of Antifungal Resistance in Transplant Infectious Diseases

Schwartz, I. S., & Patterson, T. F. (2018) · Current Infectious Disease Reports · doi:10.1007/s11908-018-0608-y · Cited by 56

Detection of TR 34 /L98H CYP51A Mutation through Passive Surveillance for Azole-Resistant Aspergillus fumigatus in the United States from 2015 to 2017

Berkow, E. L., Nunnally, N. S., Bandea, A., Kuykendall, R. J., Beer, K. D., & Lockhart, S. R. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02240-17 · Cited by 54

Fruits as the vehicle of drug resistant pathogenic yeasts

Lo, H., Tsai, S.-H., Chu, W.-L., Chen, Y.-Z., Zhou, Z.-L., Chen, H.-F., Lee, C.-F., & Yang, Y.-L. (2017) · Journal of Infection · doi:10.1016/j.jinf.2017.06.005 · Cited by 53

The fading boundaries between patient and environmental routes of triazole resistance selection in Aspergillus fumigatus

Buil, J. B., Hare, R. K., Zwaan, B. J., Arendrup, M. C., Melchers, W. J. G., & Verweij, P. E. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007858 · Cited by 53

Multiresistant Fusarium Pathogens on Plants and Humans: Solutions in (from) the Antifungal Pipeline?

Al-Hatmi, A., de Hoog, G. S., & Meis, J. F. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s180912 · Cited by 47

Occurrence of azole-resistant species of Aspergillus in the UK environment

Bromley, M., van Muijlwijk, G. H., Fraczek, M. G., Robson, G., Verweij, P. E., Denning, D. W., & Bowyer, P. (2014) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2014.05.004 · Cited by 51

SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus

Joehnk, B., Bayram, Ö., Abelmann, A., Heinekamp, T., Mattern, D. J., Brakhage, A. A., Jacobsen, I. D., Valerius, O., & Braus, G. H. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005899 · Cited by 49

Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance

Bottery, M. J., van Rhijn, N., Chown, H., Rhodes, J. L., Celia-Sanchez, B. N., Brewer, M. T., Momany, M., Fisher, M. C., Cg, K., & Bromley, M. (2024) · Nature Communications · doi:10.1038/s41467-024-54568-5 · Cited by 55

Antifungal Resistance: Specific Focus on Multidrug Resistance in Candida auris and Secondary Azole Resistance in Aspergillus fumigatus

Arıkan-Akdağlı, S., Ghannoum, M. A., & Meis, J. F. G. M. (2018) · Journal of Fungi · doi:10.3390/jof4040129 · Cited by 49

Prevalence and Therapeutic Challenges of Fungal Drug Resistance: Role for Plants in Drug Discovery

Marquez, L., & Quave, C. L. (2020) · Antibiotics · doi:10.3390/antibiotics9040150 · Cited by 55

In Vitro Acquisition of Secondary Azole Resistance in Aspergillus fumigatus Isolates after Prolonged Exposure to Itraconazole: Presence of Heteroresistant Populations

Escribano, P., Recio, S., Peláez, T., González-Rivera, M., Bouza, E., & Guinea, J. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00301-11 · Cited by 48

Azole resistance in Aspergillus fumigatus- comprehensive review

Dladla, M., Gyzenhout, M., Marais, G. J., & Ghosh, S. (2024) · Archives of Microbiology · doi:10.1007/s00203-024-04026-z · Cited by 49

Aspergilosis. Formas clínicas y tratamiento

Fortün, J., Meije, Y., Fresco, G., & Moreno, S. (2012) · Enfermedades Infecciosas y Microbiología Clínica · doi:10.1016/j.eimc.2011.12.005 · Cited by 52

Next-Generation Sequencing in the Mycology Lab

Zoll, J., Snelders, E., Verweij, P. E., & Melchers, W. J. G. (2016) · Current Fungal Infection Reports · doi:10.1007/s12281-016-0253-6 · Cited by 47

Prevalence, mechanisms and genetic relatedness of the human pathogenic fungus Aspergillus fumigatus exhibiting resistance to medical azoles in the environment of Taiwan

Wang, H., Huang, J., Lin, Y., Chen, Y., Hsieh, M., Choi, P., Lo, H., Liu, W., Hsu, C., Shih, H., et al. (2017) · Environmental Microbiology · doi:10.1111/1462-2920.13988 · Cited by 49

Genome-Wide Comparative Analysis of Aspergillus fumigatus Strains: The Reference Genome as a Matter of Concern

Garcia‐Rubio, R., Monzón, S., Alcázar‐Fuoli, L., Cuesta, I., & Mellado, E. (2018) · Genes · doi:10.3390/genes9070363 · Cited by 48

Susceptibility Test Methods: Yeasts and Filamentous Fungi

Johnson, E. M., & Arendrup, M. C. (2015) · ASM Press eBooks · doi:10.1128/9781555817381.ch131 · Cited by 45

Azole Resistance in Aspergillus fumigatus in Patients with Cystic Fibrosis: A Matter of Concern?

Hamprecht, A. G., Morio, F., Bader, O., Pape, P. L., Steinmann, J., & Dannaoui, É. (2017) · Mycopathologia · doi:10.1007/s11046-017-0162-4 · Cited by 48

Azole-resistant Aspergillus fumigatus in the Italian environment

Prigitano, A., Esposto, M. C., Romanò, L., Auxilia, F., & Tortorano, A. M. (2018) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2018.10.017 · Cited by 49

Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161

Monk, B. C., Keniya, M. V., Sabherwal, M., Wilson, R. K., Graham, D. O., Hassan, H. F., Chen, D., & Tyndall, J. D. A. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02114-18 · Cited by 46

Fungicide-driven alterations in azole-resistantAspergillus fumigatusare related to vegetable crops in Colombia, South America

Álvarez, C., Lavergne, R., Hagen, F., Morio, F., Meis, J. F. G. M., & Pape, P. L. (2019) · Mycologia · doi:10.1080/00275514.2018.1557796 · Cited by 47

Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14α-Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B

Martel, C. M., Parker, J. E., Warrilow, A. G. S., Rolley, N. J., Kelly, S. L., & Kelly, D. E. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00349-10 · Cited by 46

Epidemiología general de la enfermedad fúngica invasora

Pemán, J., & Salavert, M. (2011) · Enfermedades Infecciosas y Microbiología Clínica · doi:10.1016/j.eimc.2011.09.004 · Cited by 44

Determination of the Prevalence of Triazole Resistance in Environmental Aspergillus fumigatus Strains Isolated in South Wales, UK

Tsitsopoulou, A., Posso, R. B., Vale, L., Bebb, S., Johnson, E. M., & White, P. L. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01395 · Cited by 44

Tebuconazole induces triazole-resistance in Aspergillus fumigatus in liquid medium and soil

Cui, N., He, Y., Yao, S., Zhang, H., Ren, J., Fang, H., & Yu, Y. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.08.247 · Cited by 45

First Reported Case of Azole-Resistant Aspergillus fumigatus Due to the TR/L98H Mutation in Germany

Rath, P., Buchheidt, D., Spieß, B., Arfanis, E., Buer, J., & Steinmann, J. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01017-12 · Cited by 42

Asexual sporulation facilitates adaptation: The emergence of azole resistance inAspergillus fumigatus

Zhang, J., Debets, A. J. M., Verweij, P. E., Melchers, W. J. G., Zwaan, B. J., & Schoustra, S. E. (2015) · Evolution · doi:10.1111/evo.12763 · Cited by 44

Invasive aspergillosis: A comprehensive review

Machado, M., Fortün, J., & Muñóz, P. (2024) · Medicina Clínica · doi:10.1016/j.medcli.2024.01.045 · Cited by 41

Failure of Posaconazole Therapy in a Renal Transplant Patient with Invasive Aspergillosis Due to Aspergillus fumigatus with Attenuated Susceptibility to Posaconazole

Kuipers, S., Brüggemann, R. J. M., de Sévaux, R. G. L., Heesakkers, J. P. F. A., Melchers, W. J. G., Mouton, J. W., & Verweij, P. E. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01544-10 · Cited by 41

Emergence ofAspergillus fumigatusazole resistance in azole-naïve patients with chronic obstructive pulmonary disease and their homes

Dauchy, C., Bautin, N., Nseir, S., Reboux, G., Wintjens, R. T., Rouzic, O. L., Sendid, B., Viscogliosi, É., Pape, P. L., Arendrup, M. C., et al. (2017) · Indoor Air · doi:10.1111/ina.12436 · Cited by 41

Surveillance for azole resistance in clinical and environmental isolates of Aspergillus fumigatus in Australia and cyp51A homology modelling of azole-resistant isolates

Talbot, J. J., Subedi, S., Halliday, C. L., Hibbs, D. E., Lai, F., López-Ruiz, F. J., Harper, L., Park, R., Cuddy, W. S., Biswas, C., et al. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dky187 · Cited by 42

A single-centre, retrospective study of the incidence of invasive fungal infections during 85 years of autopsy service in Brazil

Dantas, K. C., Mauad, T., de André, C. D. S., Bierrenbach, A. L., & Saldiva, P. H. N. (2021) · Scientific Reports · doi:10.1038/s41598-021-83587-1 · Cited by 39

Composite Survival Index to Compare Virulence Changes in Azole-Resistant Aspergillus fumigatus Clinical Isolates

Mavridou, E., Meletiadis, J., Jancura, P., Abbas, S., Arendrup, M. C., Melchers, W. J. G., Heskes, T., Mouton, J. W., & Verweij, P. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072280 · Cited by 38

Yeast microbiota of raptors: a possible tool for environmental monitoring

Brilhante, R. S. N., Castelo‐Branco, D. D. S. C. M., Duarte, G. P. S., Paiva, M. D. A. N., Teixeira, C. E. C., Zeferino, J. P. O., Monteiro, A. J., Cordeiro, R. D. A., Sidrim, J. J. C., & Rocha, M. F. G. (2012) · Environmental Microbiology Reports · doi:10.1111/j.1758-2229.2011.00319.x · Cited by 37

Azole Drug Import into the Pathogenic Fungus Aspergillus fumigatus

Esquivel, B. D., Smith, A. R., Zavřel, M., & White, T. C. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05003-14 · Cited by 37

Genetic diversity of Aspergillus fumigatus in indoor hospital environments

Araújo, R., Amorim, A., & Gusmão, L. (2010) · Medical Mycology · doi:10.3109/13693780903575360 · Cited by 37

Species Distribution and Antifungal Susceptibilities of Aspergillus Section Fumigati Isolates in Clinical Samples from the United States

Badali, H., Cañete-Gibas, C. F., McCarthy, D. I., Patterson, H. P., Sanders, C. J., David, M. P., Mele, J., Fan, H., & Wiederhold, N. P. (2022) · Journal of Clinical Microbiology · doi:10.1128/jcm.00280-22 · Cited by 37

Antifungals in Clinical Use and the Pipeline

Johnson, M. D. (2021) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2021.03.005 · Cited by 35

High prevalence of fluconazole resistant Candida tropicalis among candiduria samples in China: An ignored matter of concern

Fan, X., Tsui, C. K. M., Chen, X., Wang, P., Liu, Z.-J., & Yang, C. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1125241 · Cited by 33

Prevalence of azole-resistantAspergillus fumigatusin the environment of Thailand

Tangwattanachuleeporn, M., Minarin, N., Saichan, S., Sermsri, P., Mitkornburee, R., Groß, U., Chindamporn, A., & Bader, O. (2016) · Medical Mycology · doi:10.1093/mmy/myw090 · Cited by 36

Genetic Diversity and In Vitro Antifungal Susceptibility of 200 Clinical and Environmental Aspergillus flavus Isolates

Armaki, M. T., Hedayati, M. T., Ansari, S., Omran, S. M., Saber, S., Rafati, H., Zoll, J., van der Lee, H. A., Melchers, W. J. G., Verweij, P. E., et al. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00004-17 · Cited by 37

First azole‐resistant Aspergillus fumigatus isolates with the environmental TR46/Y121F/T289A mutation in Iran

Ahangarkani, F., Puts, Y., Nabili, M., Khodavaisy, S., Moazeni, M., Salehi, Z., Kargar, M. L., Badali, H., & Meis, J. F. G. M. (2020) · Mycoses · doi:10.1111/myc.13064 · Cited by 35

Understanding the environmental drivers of clinical azole resistance in Aspergillus species

Sen, P., Vijay, M., Singh, S., Hameed, S., & Vijayaraghavan, P. (2022) · Drug Target Insights · doi:10.33393/dti.2022.2476 · Cited by 37

Molecular Characterization of a Voriconazole-Resistant, Posaconazole-Susceptible Aspergillus fumigatus Isolate in a Lung Transplant Recipient in the United States

Vázquez, J. A., & Manavathu, E. K. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01130-15 · Cited by 34

Invasive Aspergillosis: Resistance to Antifungal Drugs

Hadrich, I., Makni, F., Neji, S., Abbes, S., Cheikhrouhou, F., Trabelsi, H., Sellami, H., & Ayadi, A. (2012) · Mycopathologia · doi:10.1007/s11046-012-9526-y · Cited by 33

Algorithm to assess the presence of Aspergillus fumigatus resistant strains: The case of Norwegian sawmills

Viegas, C. S. B., Almeida, B., Caetano, L. A., Afanou, A. K., Straumfors, A., Veríssimo, C., Gonçalves, P., & Sabino, R. (2020) · International Journal of Environmental Health Research · doi:10.1080/09603123.2020.1810210 · Cited by 36

New antifungal strategies and drug development against WHO critical priority fungal pathogens

Li, Y., Liu, Y., Jiang, Y., Yang, Y., Ni, W., Zhang, W., & Tan, L. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1662442 · Cited by 38

Comparison of Two Highly Discriminatory Typing Methods to Analyze Aspergillus fumigatus Azole Resistance

Garcia‐Rubio, R., Escribano, P., Gómez, A., Guinea, J., & Mellado, E. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01626 · Cited by 33

Occupational Exposures to Organic Dust in Irish Bakeries and a Pizzeria Restaurant

Viegas, C. S. B., Fleming, G. T. A., Kadir, A. R., Almeida, B., Caetano, L. A., Gomes, A. Q., Twarużek, M., Kosicki, R., Viegas, S., & Coggins, M. A. (2020) · Microorganisms · doi:10.3390/microorganisms8010118 · Cited by 35

Azole antifungal resistance in fungal isolates from wastewater treatment plant effluents

Assress, H. A., Selvarajan, R., Nyoni, H. H., Ogola, H. J. O., Mamba, B. B., & Msagati, T. A. M. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-10688-1 · Cited by 35

Pan-azole- and multi-fungicide-resistant Aspergillus fumigatus is widespread in the United States

Celia-Sanchez, B. N., Mangum, B., Londoño, L. G., Wang, C., Shuman, B., Brewer, M. T., & Momany, M. (2024) · Applied and Environmental Microbiology · doi:10.1128/aem.01782-23 · Cited by 31

Antagonism of the Azoles to Olorofim and Cross-Resistance Are Governed by Linked Transcriptional Networks in Aspergillus fumigatus

van Rhijn, N., Hemmings, S., Storer, I. S. R., Valero, C., Shuraym, H. B., Goldman, G. H., Gsaller, F., Amich, J., & Bromley, M. (2022) · mBio · doi:10.1128/mbio.02215-22 · Cited by 31

Detecting Azole-Antifungal Resistance in Aspergillus fumigatus by Pyrosequencing

van der Torre, M. H., Frazer, L. N., & Rautemaa‐Richardson, R. (2020) · Journal of Fungi · doi:10.3390/jof6010012 · Cited by 31

Quantitative Analysis of Single-Nucleotide Polymorphism for Rapid Detection of TR 34 /L98H- and TR 46 /Y121F/T289A-Positive Aspergillus fumigatus Isolates Obtained from Patients in Iran from 2010 to 2014

Mohammadi, F., Hashemi, S. J., Zoll, J., Melchers, W. J. G., Rafati, H., Dehghan, P., Rezaie, S., Tolooe, A., Tamaddon, Y., van der Lee, H. A., et al. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02326-15 · Cited by 30

Environmental azole fungicide, prochloraz, can induce cross-resistance to medical triazoles inCandida glabrata

Faria‐Ramos, I., Tavares, P. R., Farinha, S., Neves-Maia, J., Miranda, I. M., Silva, R. M., Estevinho, L. M., Pina‐Vaz, C., & Rodrigues, A. G. (2014) · FEMS Yeast Research · doi:10.1111/1567-1364.12193 · Cited by 30

Update from the Laboratory

Bataineh, M. T. A., Sutton, D. A., Fothergill, A. W., & Wiederhold, N. P. (2015) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2015.10.014 · Cited by 30

Adoptive T‐cell therapy for fungal infections in haematology patients

Deo, S. S., & Gottlieb, D. J. (2015) · Clinical & Translational Immunology · doi:10.1038/cti.2015.16 · Cited by 30

Determination of azole fungal residues in soils and detection of Aspergillus fumigatus-resistant strains in market gardens of Eastern France

Rocchi, S., Ponçot, M., Morin‐Crini, N., Laboissière, A., Valot, B., Godeau, C., Léchenault-Bergerot, C., Reboux, G., Crini, G., & Millon, L. (2018) · Environmental Science and Pollution Research · doi:10.1007/s11356-018-3177-6 · Cited by 29

Revealing the Virulence Potential of Clinical and Environmental Aspergillus fumigatus Isolates Using Whole-Genome Sequencing

Puértolas-Balint, F., Rossen, J. W. A., dos Santos, C. O., Chlebowicz, M. A., Raangs, E. C., van Putten, M. L., Sola‐Campoy, P. J., Han, L., Schmidt, M., & García-Cobos, S. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01970 · Cited by 29

Isavuconazonium sulfate: a triazole prodrug for invasive fungal infections

Murrell, D. E., Bossaer, J. B., Carico, R. “., Harirforoosh, S., & Cluck, D. B. (2016) · International Journal of Pharmacy Practice · doi:10.1111/ijpp.12302 · Cited by 29

Diversity and origins of Indian multi‐triazole resistant strains of Aspergillus fumigatus

Chang, H., Ashu, E. E., Sharma, C., Kathuria, S., Chowdhary, A., & Xu, J. (2016) · Mycoses · doi:10.1111/myc.12494 · Cited by 27

Future Research Priorities in Fungal Resistance

McCarthy, M. W., Denning, D. W., & Walsh, T. J. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix103 · Cited by 28

Environmental Fate of the Azole Fungicide Fluconazole and Its Persistent and Mobile Transformation Product 1,2,4-Triazole

Fahy, W. D., Zhang, Z., Wang, S., Li, L., & Mabury, S. A. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.4c13539 · Cited by 28

Recent developments in Aspergillus fumigatus research: diversity, drugs, and disease

Kordana, N. E., Johnson, A., Quinn, K., Obar, J. J., & Cramer, R. A. (2025) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00011-23 · Cited by 27

Azole resistance in Aspergillus fumigatus : collateral damage of fungicide use

Snelders, E. (2012) · Radboud Repository (Radboud University) · Cited by 3

Clonal expansion and emergence of environmental multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR34/L98H

Chowdhary, A., Kathuria, S., Xu, J., Sharma, C., Sundar, H., Singh, K., Gaur, S. N., Hagen, F., Klaassen, C. H. W., & Meis, J. F. (2012)

Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?

Verweij, P. E., Snelders, E., Kema, G. H., Mellado, E., & Melchers, W. J. (2009) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(09)70265-8 · Cited by 604

Determination of antifungal susceptibility patterns among the environmental isolates of Aspergillus fumigatus in Iran

Mohammadi, F., Dehghan, P., Nekoeian, S., & Hashemi, S. J. (2016) · Advanced Biomedical Research · doi:10.4103/2277-9175.187410 · Cited by 6

Triazole fungicides and the selection of resistance to medical triazoles in the opportunistic mould Aspergillus fumigatus

Verweij, P. E., Kema, G. H., Zwaan, B., & Melchers, W. J. (2013) · Pest Management Science · doi:10.1002/ps.3390 · Cited by 67