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Fecal Microbiota Composition and Frailty
Open accessAbstract
The relationship between fecal microbiota composition and frailty in the elderly was studied. Fecal samples from volunteers with high frailty scores showed a significant reduction in the number of lactobacilli (26-fold). At much higher population levels, both the Bacteroides/Prevotella(threefold) and the Faecalibacterium prausnitzii(fourfold) groups showed a significant reduction in percentage of total number of hybridizable bacteria in the elderly with high frailty scores. In contrast to this, the number of Enterobacteriaceae was significantly higher (sevenfold) in samples from very frail volunteers.
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Additional file 2 of The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut
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Additional file 3 of The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut
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Additional file 4 of The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut
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Additional file 1 of The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut
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Additional file 6 of The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut
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Metadata
- Authors
- van Tongeren, S. P., Slaets, J. P. J., Harmsen, H. J. M., & Welling, G. W.
- Affiliations
- Department of Medical Microbiology
- University Medical Center Groningen (NL)
- Venue
- Applied and Environmental Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2005-10
- Volume
- 71
- Issue
- 10
- Pages
- 6438-6442
- ISSN
- 0099-2240 (ISSN-L)
- 1098-5336
- PMC
- PMC1265947
- OpenAlex
- W2129130754
- Cited by
- 333
- References
- 37
- Citations by year
- 2026: 6 · 2025: 14 · 2024: 21 · 2023: 15 · 2022: 28 · 2021: 39 · 2020: 24 · 2019: 26 · 2018: 28 · 2017: 22 · 2016: 18 · 2015: 15 · 2014: 16 · 2013: 9 · 2012: 6
- FWCI
- 1.76
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Applied and Environmental Microbiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, other-oa)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- fecal microbiota, frailty, older adults, lactobacilli, Bacteroides-Prevotella, Faecalibacterium prausnitzii, Enterobacteriaceae, gut microbiota, microbial diversity
- MeSH terms
- Aged, Aged, 80 and over, Bifidobacterium, Enterobacteriaceae, Feces, Humans, Lactobacillus, Colony Count, Microbial, Frail Elderly, Prevotella
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