Cited by 333Gut microbiota and healthFrailty in Older AdultsProbiotics and Fermented Foods

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Fecal Microbiota Composition and Frailty

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van Tongeren, Sandra P., Slaets, Joris P. J., Harmsen, H. J. M., Welling, Gjalt W.·2005·Applied and Environmental Microbiology

DOI 10.1128/aem.71.10.6438-6442.2005PMC PMC1265947

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Abstract

The relationship between fecal microbiota composition and frailty in the elderly was studied. Fecal samples from volunteers with high frailty scores showed a significant reduction in the number of lactobacilli (26-fold). At much higher population levels, both the Bacteroides/Prevotella(threefold) and the Faecalibacterium prausnitzii(fourfold) groups showed a significant reduction in percentage of total number of hybridizable bacteria in the elderly with high frailty scores. In contrast to this, the number of Enterobacteriaceae was significantly higher (sevenfold) in samples from very frail volunteers.

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See all 333

Authors: van Tongeren, S. P., Slaets, J. P. J., Harmsen, H. J. M., & Welling, G. W.
Affiliations: Department of Medical Microbiology
University Medical Center Groningen (NL)
ORCID: Slaets, Joris P. J.
Harmsen, H. J. M.
Venue: Applied and Environmental Microbiology
Publisher: American Society for Microbiology
Published: 2005-10
Volume: 71
Issue: 10
Pages: 6438-6442
ISSN: 0099-2240 (ISSN-L)
1098-5336
DOI: 10.1128/aem.71.10.6438-6442.2005
PMC: PMC1265947
OpenAlex: W2129130754
Cited by: 333
References: 37
Citations by year: 2026: 6 · 2025: 14 · 2024: 21 · 2023: 15 · 2022: 28 · 2021: 39 · 2020: 24 · 2019: 26 · 2018: 28 · 2017: 22 · 2016: 18 · 2015: 15 · 2014: 16 · 2013: 9 · 2012: 6
FWCI: 1.76
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Applied and Environmental Microbiology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, other-oa)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords: fecal microbiota, frailty, older adults, lactobacilli, Bacteroides-Prevotella, Faecalibacterium prausnitzii, Enterobacteriaceae, gut microbiota, microbial diversity
MeSH terms: Aged, Aged, 80 and over, Bifidobacterium, Enterobacteriaceae, Feces, Humans, Lactobacillus, Colony Count, Microbial, Frail Elderly, Prevotella

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Fecal Microbiota Composition and Frailty

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