Cited by 333Gut microbiota and healthFrailty in Older AdultsProbiotics and Fermented Foods

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Fecal Microbiota Composition and Frailty

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van Tongeren, Sandra P., Slaets, Joris P. J., Harmsen, H. J. M., Welling, Gjalt W.·2005·Applied and Environmental Microbiology

DOI 10.1128/aem.71.10.6438-6442.2005PMC PMC1265947

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Abstract

The relationship between fecal microbiota composition and frailty in the elderly was studied. Fecal samples from volunteers with high frailty scores showed a significant reduction in the number of lactobacilli (26-fold). At much higher population levels, both the Bacteroides/Prevotella(threefold) and the Faecalibacterium prausnitzii(fourfold) groups showed a significant reduction in percentage of total number of hybridizable bacteria in the elderly with high frailty scores. In contrast to this, the number of Enterobacteriaceae was significantly higher (sevenfold) in samples from very frail volunteers.

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Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics
Gibson, G. R., & Roberfroid, M. B. (1995) · Journal of Nutrition · doi:10.1093/jn/125.6.1401 · Cited by 7,659
Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations
Amann, R., Binder, B. J., Olson, R. J., Chisholm, S. W., Devereux, R., & Stahl, D. A. (1990) · Applied and Environmental Microbiology · doi:10.1128/aem.56.6.1919-1925.1990 · Cited by 4,049
Gut flora in health and disease
Guarner, F., & Malagelada, J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12489-0 · Cited by 3,480
Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut
Suau, A., Bonnet, R., Sutren, M., Godon, J.-J., Gibson, G. R., Collins, M. D., & Doré, J. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.11.4799-4807.1999 · Cited by 1,490
Temperature Gradient Gel Electrophoresis Analysis of 16S rRNA from Human Fecal Samples Reveals Stable and Host-Specific Communities of Active Bacteria
Zoetendal, E. G., Akkermans, A. D. L., & de Vos, W. M. (1998) · Applied and Environmental Microbiology · doi:10.1128/aem.64.10.3854-3859.1998 · Cited by 1,360
Analysis of Intestinal Flora Development in Breast-Fed and Formula-Fed Infants by Using Molecular Identification and Detection Methods
Harmsen, H. J. M., Wildeboer-Veloo, A. C. M., Raangs, G. C., Wagendorp, A. A., Klijn, N., BINDELS, J. G., & Welling, G. W. (2000) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200001000-00019 · Cited by 1,326
Self-citation
Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum cytophaga-flavobacter-bacteroides in the natural environment
Manz, W., Amann, R., Ludwig, W., Vancanneyt, M., & SCHLEIFER, K. H. (1996) · Microbiology · doi:10.1099/13500872-142-5-1097 · Cited by 1,176
Variations of Bacterial Populations in Human Feces Measured by Fluorescent In Situ Hybridization with Group-Specific 16S rRNA-Targeted Oligonucleotide Probes
Franks, A. H., Harmsen, H. J. M., Raangs, G. C., Jansen, G. J., Schut, F., & Welling, G. W. (1998) · Applied and Environmental Microbiology · doi:10.1128/aem.64.9.3336-3345.1998 · Cited by 1,056
Self-citation
Quantitative fluorescence in situ hybridization of Bifidobacterium spp. with genus-specific 16S rRNA-targeted probes and its application in fecal samples
Langendijk-Genevaux, P. S., Schut, F., Jansen, G. J., Raangs, G. C., Kamphuis, G. R., Wilkinson, M. H. F., & Welling, G. W. (1995) · Applied and Environmental Microbiology · doi:10.1128/aem.61.8.3069-3075.1995 · Cited by 974
Self-citation
Characterization of Bacterial Communities in Feces from Healthy Elderly Volunteers and Hospitalized Elderly Patients by Using Real-Time PCR and Effects of Antibiotic Treatment on the Fecal Microbiota
Bartosch, S., Fite, A., Macfarlane, G. T., & McMurdo, M. E. T. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.6.3575-3581.2004 · Cited by 762 · cited 3×
“(3) characterized bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by real-time PCR.”
Background

Show all 37 references

Research works printed but not linked: 2

Mitsuoka, T. 1992. Intestinal flora and ageing. Nutr. Rev.50:438-446.
Sullivan Å., R. Bennet, M. Viitanen, A.-C. Palmgren, and C. E. Nord. 2002. Influence of Lactobacillus F19 on intestinal microflora in children and elderly persons and impact on Helicobacter pylori infections. Microb. Ecol. Health Dis.3:17-21.

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Smith, B., Li, N., Andersen, A. S., Slotved, H., & Krogfelt, K. A. (2011) · The Open Microbiology Journal · doi:10.2174/1874285801105010014 · Cited by 91
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Chen, X., Pan, S., Li, F., Xu, X., & Hua, X. (2022) · Biomolecules · doi:10.3390/biom12121871 · Cited by 86
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Jayakumar, S., & Loomba, R. S. (2019) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.15314 · Cited by 87
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Candela, M., Biagi, E., Brigidi, P., O’Toole, P. W., & de Vos, W. M. (2013) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2013.12.004 · Cited by 87
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Chew, W., Lim, Y. P., Lim, W. S., Chambers, E. S., Frost, G. S., Wong, S. H., & Ali, Y. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2022.1065365 · Cited by 84
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Capri, M., Monti, D., Salvioli, S., Lescai, F., Pierini, M., Altilia, S., Sevini, F., Valensin, S., Ostan, R., Bucci, L., et al. (2006) · Artificial Organs · doi:10.1111/j.1525-1594.2006.00295.x · Cited by 81
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Lee, M., Tu, Y.-T., Lee, C., Tsai, S.-C., Hsu, H., Tsai, T., Liu, T., Young, S.-L., Lin, J., & Huang, C. (2021) · Microorganisms · doi:10.3390/microorganisms9071466 · Cited by 82
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Reeve, E., Trenaman, S. C., Rockwood, K. J., & Hilmer, S. N. (2017) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2017.1325873 · Cited by 87

Authors: van Tongeren, S. P., Slaets, J. P. J., Harmsen, H. J. M., & Welling, G. W.
Affiliations: Department of Medical Microbiology
University Medical Center Groningen (NL)
ORCID: Slaets, Joris P. J.
Harmsen, H. J. M.
Venue: Applied and Environmental Microbiology
Publisher: American Society for Microbiology
Published: 2005-10
Volume: 71
Issue: 10
Pages: 6438-6442
ISSN: 0099-2240 (ISSN-L)
1098-5336
DOI: 10.1128/aem.71.10.6438-6442.2005
PMC: PMC1265947
OpenAlex: W2129130754
Cited by: 333
References: 37
Citations by year: 2026: 6 · 2025: 14 · 2024: 21 · 2023: 15 · 2022: 28 · 2021: 39 · 2020: 24 · 2019: 26 · 2018: 28 · 2017: 22 · 2016: 18 · 2015: 15 · 2014: 16 · 2013: 9 · 2012: 6
FWCI: 1.76
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Applied and Environmental Microbiology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, other-oa)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords: fecal microbiota, frailty, older adults, lactobacilli, Bacteroides-Prevotella, Faecalibacterium prausnitzii, Enterobacteriaceae, gut microbiota, microbial diversity
MeSH terms: Aged, Aged, 80 and over, Bifidobacterium, Enterobacteriaceae, Feces, Humans, Lactobacillus, Colony Count, Microbial, Frail Elderly, Prevotella

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