The ABCs of Candida albicans multidrug transporter Cdr1

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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

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Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus

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Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene

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Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals

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Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in <i>Candida albicans</i> Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients

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Genome-Wide Fitness Test and Mechanism-of-Action Studies of Inhibitory Compounds in Candida albicans

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Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters

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Yeast ATP-Binding Cassette Transporters Conferring Multidrug Resistance

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AP1-mediated Multidrug Resistance in Saccharomyces cerevisiae Requires FLR1 Encoding a Transporter of the Major Facilitator Superfamily

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ABC Transporters in Saccharomyces cerevisiae and Their Interactors: New Technology Advances the Biology of the ABCC (MRP) Subfamily

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A common drug‐responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2 , two genes involved in antifungal drug resistance

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Efflux pump proteins in antifungal resistance

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Rapid, Transient Fluconazole Resistance in <i>Candida albicans</i> Is Associated with Increased mRNA Levels of <i>CDR</i>

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Candida and candidiasis in HIV-infected patients: where commensalism, opportunistic behavior and frank pathogenicity lose their borders

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Fungal PDR transporters: Phylogeny, topology, motifs and function

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ABC Transporter Cdr1p Contributes More than Cdr2p Does to Fluconazole Efflux in Fluconazole-Resistant Candida albicans Clinical Isolates

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Genetic Separation of FK506 Susceptibility and Drug Transport in the Yeast Pdr5 ATP-binding Cassette Multidrug Resistance Transporter

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A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5

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Functional Characterization of <i>Candida albicans</i> ABC Transporter Cdr1p

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Role of Translocases in the Generation of Phosphatidylserine Asymmetry

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Molecular aspects of fluconazole resistance development in <i>Candida albicans</i>

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Relative Contributions of the <i>Candida albicans</i> ABC Transporters Cdr1p and Cdr2p to Clinical Azole Resistance

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Multidrug Transporters CaCdr1p and CaMdr1p of <i>Candida albicans</i> Display Different Lipid Specificities: both Ergosterol and Sphingolipids Are Essential for Targeting of CaCdr1p to Membrane Rafts

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Multidrug efflux pumps: Substrate selection in ATP‐binding cassette multidrug efflux pumps – first come, first served?

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Genome-Wide Expression and Location Analyses of the Candida albicans Tac1p Regulon

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Genomewide Location Analysis of <i>Candida albicans</i> Upc2p, a Regulator of Sterol Metabolism and Azole Drug Resistance

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Curcumin Modulates Efflux Mediated by Yeast ABC Multidrug Transporters and Is Synergistic with Antifungals

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The Quorum-Sensing Molecule Farnesol Is a Modulator of Drug Efflux Mediated by ABC Multidrug Transporters and Synergizes with Drugs in Candida albicans

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Identification of the <i>Candida albicans</i> Cap1p Regulon

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ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators

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Inducible Azole Resistance Associated with a Heterogeneous Phenotype in Candida albicans

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MFS transportome of the human pathogenic yeast Candida albicans

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Cellular and Molecular Biology of Candida albicans Estrogen Response

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CaNdt80 Is Involved in Drug Resistance in Candida albicans by Regulating CDR1

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Expression of CDR1, a multidrug resistance gene of Candida albicans: transcriptional activation by heat shock, drugs and human steroid hormones

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Analysis of a fungus‐specific transcription factor family, the <i><scp>C</scp>andida albicans</i> zinc cluster proteins, by artificial activation

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Complete Inventory of ABC Proteins in Human Pathogenic Yeast, Candida albicans

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Mutations Define Cross-talk between the N-terminal Nucleotide-binding Domain and Transmembrane Helix-2 of the Yeast Multidrug Transporter Pdr5

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Resistance of artificial biofilms of Pseudomonas aeruginosa to imipenem and tobramycin

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Characterisation of human steroid hormone transport mediated by Cdr1p, a multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family

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Heterogeneous mechanisms of azole resistance in Candida albicans clinical isolates from an HIV-infected patient on continuous fluconazole therapy for oropharyngeal candidosis

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Functional analysis of a vacuolar ABC transporter in wild‐type Candida albicans reveals its involvement in virulence

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Disulfiram is a potent modulator of multidrug transporter Cdr1p of Candida albicans

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SRE1 and SRE2 are two specific steroid‐responsive modules of Candida drug resistance gene 1 (CDR1) promoter

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A Ste6p/P‐glycoprotein homologue from the asexual yeast Candida albicans transports the a‐factor mating pheromone in Saccharomyces cerevisiae

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Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a d ‐octapeptide derivative inhibitor

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Insight into Pleiotropic Drug Resistance ATP-binding Cassette Pump Drug Transport through Mutagenesis of Cdr1p Transmembrane Domains*

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Purification and Characterization of the N-Terminal Nucleotide Binding Domain of an ABC Drug Transporter of Candida albicans: Uncommon Cysteine 193 of Walker A Is Critical for ATP Hydrolysis

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Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux

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Role of ABC Transporters in Aureobasidin A Resistance

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The Signaling Interface of the Yeast Multidrug Transporter Pdr5 Adopts a Cis Conformation, and There Are Functional Overlap and Equivalence of the Deviant and Canonical Q-Loop Residues

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CDR1, a multidrug resistance gene from Candida albicans, contains multiple regulatory domains in its promoter and the distal AP-1 element mediates its induction by miconazole

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Transcriptional Activation and Increased mRNA Stability Contribute to Overexpression of CDR1 in Azole-Resistant Candida albicans

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Mutational Analysis of Intracellular Loops Identify Cross Talk with Nucleotide Binding Domains of Yeast ABC Transporter Cdr1p

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ABC multidrug transporter Cdr1p of has divergent nucleotide-binding domains which display functional asymmetry

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Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans

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Conserved Asp327 of Walker B Motif in the N-Terminal Nucleotide Binding Domain (NBD-1) of Cdr1p ofCandida albicansHas Acquired a New Role in ATP Hydrolysis

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Candida Drug Resistance Protein 1, a Major Multidrug ATP Binding Cassette Transporter of Candida albicans, Translocates Fluorescent Phospholipids in a Reconstituted System

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PAP1 [poly(A) polymerase 1] homozygosity and hyperadenylation are major determinants of increased mRNA stability of CDR1 in azole-resistant clinical isolates of Candida albicans

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The DNA-binding domain of CaNdt80p is required to activate CDR1 involved in drug resistance in Candida albicans

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Chimeras of the ABC drug transporter Cdr1p reveal functional indispensability of transmembrane domains and nucleotide-binding domains, but transmembrane segment 12 is replaceable with the corresponding homologous region of the non-drug transporter Cdr3p

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Functional Characterization of N-Terminal Nucleotide Binding Domain (NBD-1) of a Major ABC Drug Transporter Cdr1p of Candida albicans: Uncommon but Conserved Trp326 of Walker B Is Important for ATP Binding

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Cloning and characterization of 1,3‐β‐glucanase‐encoding genes from non‐conventional yeasts

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Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeable

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Vaginal yeast infections during pregnancy.

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Another Link between Phospholipid Transmembrane Migration and ABC Transporter Gene Family, Inferred from a Rare Inherited Disorder of Phosphatidylserine Externalization

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Ncb2 Is Involved in Activated Transcription of CDR1 in Azole-Resistant Clinical Isolates of Candida albicans

Shukla, S., Yadav, V., Mukhopadhyay, G., & Prasad, R. (2011) · Eukaryotic Cell · doi:10.1128/ec.05041-11 · Cited by 19 · see citing works

A novel catalytic mechanism for ATP hydrolysis employed by the N-terminal nucleotide-binding domain of Cdr1p, a multidrug ABC transporter of Candida albicans

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ABC transporter Cdr1p harbors charged residues in the intracellular loop and nucleotide-binding domain critical for protein trafficking and drug resistance

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Biofilm of Candida albicans : formation, regulation and resistance

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Diagnosis of invasive fungal infections: challenges and recent developments

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Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal

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Biofilm formation in medically important Candida species

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Molecular and genetic basis of azole antifungal resistance in the opportunistic pathogenic fungus<i>Candida albicans</i>

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Fungal Drug Response and Antimicrobial Resistance

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ABC Transporter Genes Show Upregulated Expression in Drug-Resistant Clinical Isolates of Candida auris: A Genome-Wide Characterization of ATP-Binding Cassette (ABC) Transporter Genes

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River bacterial community structure and co-occurrence patterns under the influence of different domestic sewage types

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Multiple roles of ABC transporters in yeast

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Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens

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Small molecule II-6s synergises with fluconazole against Candida albicans

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An A666G mutation in transmembrane helix 5 of the yeast multidrug transporter Pdr5 increases drug efflux by enhancing cooperativity between transport sites

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Generation of antifungals to combat drug resistance using language models and diffusion models

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Unravelling Drug Resistance in Candida Species: Genetic, Biofilm, Transcriptional, and Epigenetic Perspectives

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Inventory of ABC proteins and their putative role in salt and drug tolerance in Debaryomyces hansenii

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Transcriptome Analysis of mfs2-Defective Penicillium digitatum Mutant to Reveal Importance of Pdmfs2 in Developing Fungal Prochloraz Resistance

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Genomic landscape of the DHA1 family in Candida auris and mapping substrate repertoire of CauMdr1

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Acquired resistance or tolerance? – in search of mechanisms underlying changes in the resistance profile of Candida albicans and Candida parapsilosis as a result of exposure to methotrexate

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A State-of-the-art Review and Prospective Therapeutic Applications of Prenyl Flavonoids as Chemosensitizers against Antifungal Multidrug Resistance in Candida albicans

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Bioinformatic Identification of ABC Transporters in Candida auris

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The E-helix is a central core in a conserved helical bundle involved in nucleotide binding and transmembrane domain intercalation in the ABC transporter superfamily

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Antifungal peptide APTs exerts its fungistatic effect against Candida albicans through interaction with lipid rafts

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Computational Approaches for Discovering Virulence Factors in Coccidioides

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Nanotechnology-driven synergy: research effects of curcumin nanosuspension and fluconazole combination in overcoming azole resistance in Candida albicans

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Dual inhibition of ERG11 and CDR2 in drug-resistant Candida albicans by Indian phytochemicals: a combined in silico–in vitro approach

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Coordinated regulation of Mdr1- and Cdr1-mediated protection from antifungals by the Mrr1 transcription factor in emerging Candida spp.

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ABC-finder: A containerized web server for the identification and topology prediction of ABC proteins

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Gene Expression Analysis of Key Players Associated with Fluconazole Resistance in Candida albicans

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Metabolic fitness of Candida albicans is indispensable for functional drug efflux, ergosterol, and chitin biosynthesis

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Crosstalk between iron and flavins in the opportunistic fungal pathogen Candida albicans

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