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Virulence Factors of Clostridioides (Clostridium) difficile Linked to Recurrent Infections

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Screening for Asymptomatic Clostridioides difficile Carriage Among Hospitalized Patients: A Narrative Review

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What’s a Biofilm?—How the Choice of the Biofilm Model Impacts the Protein Inventory of Clostridioides difficile

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Characterisation of Clostridium difficile strains isolated from Groote Schuur Hospital, Cape Town, South Africa

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Assembly of the exosporium layer in Clostridioides difficile spores

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A High-Carbohydrate Diet Prolongs Dysbiosis and Clostridioides difficile Carriage and Increases Delayed Mortality in a Hamster Model of Infection

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The small acid-soluble proteins of spore-forming organisms: similarities and differences in function

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Subboiling Moist Heat Favors the Selection of Enteric PathogenClostridium difficilePCR Ribotype 078 Spores in Food

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Pilin Vaccination Stimulates Weak Antibody Responses and Provides No Protection in a C57Bl/6 Murine Model of Acute Clostridium difficile Infection

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The Burden of Clostridium difficile after Cervical Spine Surgery

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Cysteine Protease-Mediated Autocleavage of Clostridium difficile Toxins Regulates Their Proinflammatory Activity

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Mucosal Vaccination Strategies against Clostridioides difficile Infection

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Reviewing the Clostridioides difficile Mouse Model: Insights into Infection Mechanisms

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Clostridioides difficile spores stimulate inflammatory cytokine responses and induce cytotoxicity in macrophages

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Long-Term Use of Antibiotics and Risk of Parkinson’s Disease in the Nurses’ Health Study

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Outbreaks of Typhlocolitis Caused by Hypervirulent Group ST1 Clostridioides difficile in Highly Immunocompromised Strains of Mice

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The blueprint for building a biofilm the Clostridioides difficile way

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Clostridium difficile toxin B intoxicated mouse colonic epithelial CT26 cells stimulate the activation of dendritic cells

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Disparate subcellular location of putative sortase substrates in Clostridium difficile

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Leveraging Quality Improvement Science to Reduce C. difficile Infections in a Community Hospital

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Clostridium difficile shows no trade-off between toxin and spore production within the human host

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How nutrient starvation impacts the gut microbiome

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Berry, E. D., & Wells, J. E. (2018) · ASM Press eBooks · doi:10.1128/9781555819644.ch10 · Cited by 4

PATHOGENIC SPECIES OF CLOSTRIDIA AND THEIR ANTIBIOTIC RESISTANCE, VIRULENCE FACTORS, AND GENOMIC FEATURES

Bezborodova, N. A., Sokolova, O. N., Kozhukhovskaya, V. V., Tomskikh, O. G., Pechura, E., & Suzdaltseva, M. A. (2023) · Innovations and Food Safety · doi:10.31677/2311-0651-2023-41-3-39-51 · Cited by 4

Epizootic of enterocolitis and clostridial overgrowth in NSG and NSG-related mouse strains

Arthur, J. D., Mullen, J. L., Uzal, F. A., Nagamine, C. M., & Casey, K. M. (2023) · Veterinary Pathology · doi:10.1177/03009858231217197 · Cited by 4

Contribution des modèles mathématiques à la compréhension de la dynamique de diffusion des bactéries multi-résistantes à l’hôpital

Opatowski, L., de Cellès, M. D., Souissi, S., Kardaś-Słoma, L., Temime, L., & Guillemot, D. (2013) · Journal des Anti-infectieux · doi:10.1016/j.antinf.2013.09.002 · Cited by 4

Socializing, networking and development: a report from the second ‘ Y oung M icrobiologists S ymposium on M icrobe S ignalling, O rganization and P athogenesis’

Caly, D. L., Coulthurst, S. J., Geoghegan, J. A., Malone, J. G., & Ryan, R. P. (2012) · Molecular Microbiology · doi:10.1111/mmi.12016 · Cited by 4

Incidence, risk factors, and outcome of Clostridioides difficile infection following urological surgeries

Nguyen, K. A., Le, D. Q., Bui, Y., Advani, S. D., Renzulli, J., Kenney, P. A., & Leapman, M. (2021) · World Journal of Urology · doi:10.1007/s00345-020-03551-y · Cited by 4

Diet-Induced Alteration of the Murine Intestinal Microbiome Following Antibiotic Ablation

Irvin, A. P., Cockburn, A., Primerano, D. A., Denvir, J., Bošković, G., Infante, A. M., Wu, G. D., & Cuff, C. F. (2017) · Advances in Microbiology · doi:10.4236/aim.2017.77043 · Cited by 5

Outbreak of Murine Infection with Clostridium difficile Associated with the Administration of a Pre- and Perinatal Methyl Donor Diet

Mau, T., Eckley, S. S., Bergin, I. L., Saund, K., Villano, J., Vendrov, K. C., Snitkin, E. S., Young, V. B., & Yung, R. L. (2019) · mSphere · doi:10.1128/mspheredirect.00138-19 · Cited by 4

Mechanisms of bacterial host-to-host transmission

Zafar, M. A., Hernandez, G. E., & Walker, K. A. (2025) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00259-24 · Cited by 3

Murine Models of Klebsiella pneumoniae Gastrointestinal Infection

Valencia‐Bacca, J. D., Islam, M. M., Haas, K. M., & Zafar, M. A. (2025) · Current Protocols · doi:10.1002/cpz1.70187 · Cited by 3

Effect of Clindamycin on Intestinal Microbiome and Miltefosine Pharmacology in Hamsters Infected with Leishmania infantum

Olías-Molero, A. I., Botías, P., Cuquerella, M., García‐Cantalejo, J., Barcia, E., Torrado, S., Torrado, J. J., & Alunda, J. M. (2023) · Antibiotics · doi:10.3390/antibiotics12020362 · Cited by 3

Cultivation of Spore-Forming Gut Microbes Using a Combination of Bile Acids and Amino Acids

Onizuka, S., Tanaka, M., Mishima, R., & Nakayama, J. (2021) · Microorganisms · doi:10.3390/microorganisms9081651 · Cited by 3

Control ofClostridium difficileinfection in the hospital setting

Wiuff, C., Murdoch, H., & Coia, J. E. (2014) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2014.894459 · Cited by 3

Clostridium difficile – A Pathogen on the Move

Faulds‐Pain, A., Martin, M. J., & Wren, B. W. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397169-2.00058-5 · Cited by 3

Insights into the regulatory mechanisms of Clostridioides difficile biofilm formationPreprint

Buckley, A. M., Ewin, D. J., Moura, I. B., Wilcox, M. H., & Douce, G. R. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.02.19.431970 · Cited by 3

Novel drivers of virulence in Clostridioides difficile identified via context-specific metabolic network analysisPreprint

Jenior, M. L., Leslie, J. L., Powers, D. A., Garrett, E. M., Walker, K. A., Dickenson, M. E., Petri, W. A., Tamayo, R., & Papin, J. A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.09.373480 · Cited by 3

Multiple evolutionary pathways lead to vancomycin resistance in Clostridioides difficilePreprint

Buddle, J. E., Wright, R. C. T., Turner, C. E., Chaudhuri, R. R., Brockhurst, M. A., & Fagan, R. P. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.15.557922 · Cited by 3

Clustering Disease of Clostridioides Difficile Infection: Implication for the Management in Internal Medicine

Crispino, P. (2023) · Microbiology Research · doi:10.3390/microbiolres14030094 · Cited by 2

In vitro characterization of PHICD111_20024_EAD as an engineered endolysin against Clostridioides difficile

Park, J., Yoo, S., An, J., Cho, Y., Park, K., Hwang, J., Chun, S.-I., Kang, N. J., Seo, M., & Yoon, H. (2025) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2025.08.009 · Cited by 2

Host tracheal and intestinal microbiomes inhibit Coccidioides growth in vitro

Tejeda-Garibay, S., Zhao, L., Hum, N. R., Pimentel, M., Diep, A. L., Amiri, B., Sindi, S., Weilhammer, D. R., Loots, G. G., & Hoyer, K. K. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.02978-23 · Cited by 2

The Human Microbiota and Pathogen Interactions

Walker, A. W. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397169-2.00019-6 · Cited by 2

The impact of changing reflexive to clinician-ordered Clostridioides difficile polymerase chain reaction (PCR) testing for indeterminate cases: Cost savings without associated adverse events

Sullivan, E. L., Majumdar, R., Ortiz, C., Riggs, P. K., & Crum‐Cianflone, N. F. (2020) · Infection Control and Hospital Epidemiology · doi:10.1017/ice.2020.56 · Cited by 2

Microbiology: Supershedding mice

(2009) · Nature · doi:10.1038/460155a

Articles of Significant Interest Selected from This Issue by the Editors

(2009) · Infection and Immunity · doi:10.1128/iai.00803-09

Murine models to study Clostridium difficile infection and transmission

Lawley, T. D., & Young, V. B. (2013) · Anaerobe · doi:10.1016/j.anaerobe.2013.09.008 · Cited by 31

The Clostridium difficile spo0A Gene Is a Persistence and Transmission Factor

Fairweather, N. F., Dougan, B. G., & Lawleyd, T. D. (2016)

Toxin-positive Clostridium difficile latently infect mouse colonies and protect against highly pathogenic C. difficile

Etienne‐Mesmin, L., Chassaing, B., Adekunle, O., Mattei, L. M., Bushman, F. D., & Gewirtz, A. T. (2017) · Gut · doi:10.1136/gutjnl-2016-313510 · Cited by 35