Thinking beyond the Common Candida Species: Need for Species-Level Identification of Candida Due to the Emergence of Multidrug-Resistant Candida auris
Open accessAbstract
Candida species are one of the leading causes of nosocomial infections. Because much of the treatment for Candida infections is empirical, some institutions do not identify Candida to species level. With the worldwide emergence of the multidrug-resistant species Candida auris , identification of Candida to species level has new clinical relevance. Species should be identified for invasive candidiasis isolates, and species-level identification can be considered for selected noninvasive isolates to improve detection of C. auris .
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The relatively low percentage of blood clinical cases in the West might reflect regional differences in case reporting and in testing practices for C. auris in noninvasive body sites.
“The volume of screening cases and frequency of clinical cases was greatest in the West, but the region had a relatively low percentage of clinical cases involving blood; that finding might reflect regional differences in case reporting and in testing practices for C. auris in noninvasive body sites (8).”
From Progression from <i>Candida auris</i> Colonization Screening to Clinical Case Status, United States, 2016–2023 (2025) · cites this paper as [8]
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- Authors
- Lockhart, S. R., Jackson, B. R., Vallabhaneni, S., Ostrosky-Zeichner, L., Pappas, P. G., & Chiller, T.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Division of Infectious Diseases, University of Texas Health Science Center, Houston, Texas, USA
- University of Alabama at Birmingham (US)
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2017-12
- Volume
- 55
- Issue
- 12
- Pages
- 3324-3327
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- PMC
- PMC5703798
- OpenAlex
- W2754863888
- Cited by
- 61
- References
- 19
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 6 · 2020: 10 · 2019: 12 · 2018: 13 · 2017: 1
- FWCI
- 7.58
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Microbiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Keywords
- Candida auris, species identification, Candida, multidrug resistance, invasive candidiasis, nosocomial infections, empirical antifungal therapy, fungal identification
- MeSH terms
- Antifungal Agents, Candida, Candidiasis, Humans, Microbiological Techniques, Drug Resistance, Multiple, Fungal
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