Use of Fluconazole as a Surrogate Marker To Predict Susceptibility and Resistance to Voriconazole among 13,338 Clinical Isolates of Candida spp. Tested by Clinical and Laboratory Standards Institute-Recommended Broth Microdilution Methods
Open accessAbstract
Clinical laboratories frequently face the problem of delayed availability of commercially prepared approved reagents for performing susceptibility testing of new antimicrobials. Although this problem is encountered more often with antibacterial agents, it is also an issue with antifungal agents. A current example is voriconazole, a new triazole antifungal with an expanded spectrum and potency against Candida spp., Aspergillus spp., and other opportunistic fungal pathogens. The present study addresses the use of fluconazole as a surrogate marker to predict the susceptibility of Candida spp. to voriconazole. Reference broth microdilution MIC results for 13,338 strains of Candida spp. isolated from more than 200 medical centers worldwide were used. Voriconazole MICs and interpretive categories (susceptible, ≤1 μg/ml; susceptible dose dependent, 2 μg/ml; resistant, ≥4 μg/ml) were compared with those of fluconazole by regression statistics and error rate bounding analyses. For all 13,338 isolates, the absolute categorical agreement was 91.6% (false susceptible or very major error [VME], 0.0%). Since voriconazole is 16- to 32-fold more potent than fluconazole, the performance of fluconazole as a surrogate marker for voriconazole susceptibility was improved by designating those isolates with fluconazole MICs of ≤32 μg/ml as being susceptible to voriconazole, resulting in a categorical agreement of 97% with 0.1% VME. Clinical laboratories performing antifungal susceptibility testing of fluconazole against Candida spp. can reliably use these results as surrogate markers until commercial FDA-approved voriconazole susceptibility tests become available.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Variations in the structure of azoles are responsible for the cross-resistance patterns among Candida species.
“It appears that variations in the structure of azoles are responsible for the cross-resistance patterns among Candida species [92–94].”
From <i>Candida</i>Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents (2013) · cites this paper as [93]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically
Ferraro, M. J. (2000) · Cited by 16,875 · see citing works
National Committee for Clinical Laboratory Standards
Bruck, E. (1980) · PEDIATRICS · doi:10.1542/peds.65.1.187 · Cited by 14,736 · see citing works
Manual of Clinical Microbiology.
(1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-93-6-939_2 · Cited by 14,435 · see citing works
Wikler, M. A., & Clinical (2006) · Clinical and Laboratory Standards Institute eBooks · Cited by 2,842 · see citing works
Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard
Wikler, M. A., & Clinical (2012) · Medical Entomology and Zoology · Cited by 897 · see citing works
Rex, J. H., Pfaller, M. A., Galgiani, J. N., Bartlett, M. S., Espinel-Ingroff, A., Ghannoum, M. A., Lancaster, M., Odds, F. C., Rinaldi, M. G., Walsh, T. J., et al. (1997) · Clinical Infectious Diseases · doi:10.1093/clinids/24.2.235 · Cited by 855 · see citing works
Self-citationVoriconazole: A New Triazole Antifungal Agent
Johnson, L. B., & Kauffman, C. A. (2003) · Clinical Infectious Diseases · doi:10.1086/367933 · Cited by 782 · see citing works
Voriconazole Treatment for Less‐Common, Emerging, or Refractory Fungal Infections
Perfect, J. R., Marr, K. A., Walsh, T. J., Greenberg, R. N., Dupont, B., Torre‐Cisneros, J., Just‐Nübling, G., Schlamm, H. T., Lutsar, I., Espinel‐Ingroff, A., et al. (2003) · Clinical Infectious Diseases · doi:10.1086/374557 · Cited by 672 · see citing works
Kullberg, B., Sobel, J., Ruhnke, M., Pappas, P., Viscoli, C., Rex, J., Cleary, J., Rubinstein, E., Church, L., Brown, J., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67490-9 · Cited by 521 · see citing works
Pfaller, M. A., & Diekema, D. J. (2004) · Clinical Microbiology and Infection · doi:10.1111/j.1470-9465.2004.t01-1-00844.x · Cited by 422 · see citing works
Self-citationBreakthrough Fungal Infections in Stem Cell Transplant Recipients Receiving Voriconazole
Imhof, A., Balajee, S. A., Fredricks, D. N., Englund, J. A., & Marr, K. A. (2004) · Clinical Infectious Diseases · doi:10.1086/423274 · Cited by 402 · see citing works
Has antifungal susceptibility testing come of age
Rex, J. H., & Pfaller, M. A. (2002) · Clinical Infectious Diseases · doi:10.1086/342384 · Cited by 361 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., & Sheehan, D. J. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.19.2.435-447.2006 · Cited by 298 · see citing works
Self-citationPfaller, M. A., & Diekema, D. J. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.10.3551-3557.2002 · Cited by 269 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., Rex, J. H., Espinel-Ingroff, A., Johnson, E. M., Andes, D., Chaturvedi, V., Ghannoum, M. A., Odds, F. C., Rinaldi, M. G., et al. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.44.3.819-826.2006 · Cited by 258 · see citing works
Self-citationCandida, Cryptococcus, and Other Yeasts of Medical Importance
Howell, S. A., & Hazen, K. C. (2011) · Wiley eBooks · doi:10.1128/9781555816728.ch115 · Cited by 249 · see citing works
Self-citationPfaller, M. A., Messer, S. A., Hollis, R. J., Jones, R. N., & Diekema, D. J. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.6.1723-1727.2002 · Cited by 232 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., Messer, S. A., Boyken, L. B., & Hollis, R. J. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.4.1440-1446.2003 · Cited by 185 · see citing works
Self-citationIn Vivo Pharmacodynamics of Antifungal Drugs in Treatment of Candidiasis
Andes, D. R. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.4.1179-1186.2003 · Cited by 170 · see citing works
Voriconazole: A New Triazole Antifungal Agent
Pearson, M., Rogers, P. D., Cleary, J. D., & Chapman, S. W. (2003) · Annals of Pharmacotherapy · doi:10.1345/aph.1c261 · Cited by 145 · see citing works
Clinical Significance of Azole Antifungal Drug Cross-Resistance in Candida glabrata
Panackal, A. A., Gribskov, J. L., Staab, J. F., Kirby, K. A., Rinaldi, M. G., & Marr, K. A. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.44.5.1740-1743.2006 · Cited by 144 · see citing works
Magill, S. S., Shields, C. E., Sears, C. L., Choti, M. A., & Merz, W. G. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.44.2.529-535.2006 · Cited by 137 · see citing works
Espinel‐Ingroff, A., Pfaller, M. A., Messer, S. A., Knapp, C. C., Killian, S. B., Norris, H. A., & Ghannoum, M. A. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.3.591-595.1999 · Cited by 133 · see citing works
Self-citationVoriconazole Salvage Treatment of Invasive Candidiasis
Ostrosky‐Zeichner, L., Lashof, A. M. L. O., Kullberg, B. J., & Rex, J. H. (2003) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-003-1014-3 · Cited by 125 · see citing works
Genetic Basis for Differential Activities of Fluconazole and Voriconazole against Candida krusei
Fukuoka, T., Johnston, D. A., Winslow, C. A., de Groot, M. J., Burt, C., Hitchcock, C. A., & Filler, S. G. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.4.1213-1219.2003 · Cited by 97 · see citing works
Candida glabrata Fungemia in Transplant Patients Receiving Voriconazole after Fluconazole
Alexander, B. D., Schell, W. A., Miller, J. L., Long, G. D., & Perfect, J. R. (2005) · Transplantation · doi:10.1097/01.tp.0000173771.47698.7b · Cited by 78 · see citing works
Joly, S., Pujol, C., Rysz, M. W., Vargas, K. G., & Soll, D. R. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.4.1035-1044.1999 · Cited by 76 · see citing works
Pfaller, M. A., Messer, S. A., Boyken, L., Rice, C., Tendolkar, S., Hollis, R. J., & Diekema, D. J. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.7.3137-3141.2004 · Cited by 66 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., Boyken, L. B., Messer, S. A., Tendolkar, S., & Hollis, R. J. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.5.1875-1880.2003 · Cited by 51 · see citing works
Self-citationJones, R. N., & Pfaller, M. A. (2001) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/s0732-8893(01)00229-2 · Cited by 22 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., Messer, S. A., Boyken, L. B., Huynh, H. K., & Hollis, R. J. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.5.1694-1697.2002 · Cited by 15 · see citing works
Self-citationVoriconazole for candidosis: an important addition?
Graybill, J. R. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67579-4 · Cited by 11 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Solomkin, J. S., Mazuski, J. E., Bradley, J. S., Rodvold, K. A., Goldstein, E. J. C., Baron, E. J., O’Neill, P. J., Chow, A. W., Dellinger, E. P., Eachempati, S. R., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/649554 · Cited by 1,571 · see citing works
DEPARTMENT OF HEALTH & HUMAN SERVICES
Schuchat, A. (2015) · Pharmacy Today · doi:10.1016/s1042-0991(15)32122-8 · Cited by 1,108 · see citing works
Epidemiology of Invasive Mycoses in North America
Pfaller, M. A., & Diekema, D. J. (2010) · Critical Reviews in Microbiology · doi:10.3109/10408410903241444 · Cited by 901 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., Turnidge, J. D., Castanheira, M., & Jones, R. N. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofy358 · Cited by 825 · see citing works
Self-citationSolomkin, J. S., Mazuski, J. E., Bradley, J. S., Rodvold, K. A., Goldstein, E. J. C., Baron, E. J., O’Neill, P. J., Chow, A. W., Dellinger, E. P., Eachempati, S. R., et al. (2010) · Surgical Infections · doi:10.1089/sur.2009.9930 · Cited by 620 · see citing works
Resistance to Antifungal Agents: Mechanisms and Clinical Impact
Kanafani, Z. A., & Perfect, J. R. (2008) · Clinical Infectious Diseases · doi:10.1086/524071 · Cited by 619 · see citing works
Spampinato, C., & Leonardi, D. (2013) · BioMed Research International · doi:10.1155/2013/204237 · Cited by 411 · see citing works
Pfaller, M. A., Diekema, D. J., Gibbs, D. L., Newell, V. A., Hu, B., Dzierzanowska, D., Климко, Н. Н., Letscher‐Bru, V., Lisalová, M., Muehlethaler, K., et al. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.01747-08 · Cited by 370 · see citing works
Self-citationNett, J. E., & Andes, D. R. (2016) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2015.10.012 · Cited by 351 · see citing works
Garcia-Effron, G., Lee, S., Park, S., Cleary, J. D., & Perlin, D. S. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00443-09 · Cited by 323 · see citing works
Pfaller, M. A., Andes, D., Diekema, D. J., Espinel-Ingroff, A., & Sheehan, D. (2010) · Drug Resistance Updates · doi:10.1016/j.drup.2010.09.002 · Cited by 314 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., Gibbs, D. L., Newell, V. A., Meis, J. F. G. M., Gould, I. M., Fu, W., Colombo, A. L., & Rodríguez-Noriega, E. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.00409-07 · Cited by 287 · see citing works
Self-citationGarcia-Effron, G., Park, S., & Perlin, D. S. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01162-08 · Cited by 256 · see citing works
Pfaller, M. A., Andes, D., Arendrup, M. C., Diekema, D. J., Espinel-Ingroff, A., Alexander, B. D., Brown, S. D., Chaturvedi, V., Fowler, C. L., Ghannoum, M. A., et al. (2011) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2011.03.002 · Cited by 130 · see citing works
Self-citationPfaller, M. A., Messer, S. A., Hollis, R. J., Boyken, L. B., Tendolkar, S., Kroeger, J. S., & Diekema, D. J. (2009) · Journal of Clinical Microbiology · doi:10.1128/jcm.00946-09 · Cited by 128 · see citing works
Self-citationTrends in antifungal susceptibility testing using CLSI reference and commercial methods
Cantón, E., Espinel‐Ingroff, A., & Pemán, J. (2009) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.7.1.107 · Cited by 113 · see citing works
Impact of New Antifungal Breakpoints on Antifungal Resistance in Candida Species
Fothergill, A. W., Sutton, D. A., McCarthy, D. I., & Wiederhold, N. P. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.03044-13 · Cited by 96 · see citing works
Meng, F.-Y., Zuo, G., Hao, X., Wang, G., Xiao, H., Zhang, J., & Xu, G.-L. (2009) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2009.07.029 · Cited by 88 · see citing works
Pfaller, M. A., Diekema, D. J., Procop, G. W., & Rinaldi, M. G. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.01986-06 · Cited by 76 · see citing works
Self-citationPfaller, M. A., Messer, S. A., Diekema, D. J., Jones, R. N., & Castanheira, M. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.02481-13 · Cited by 74 · see citing works
Self-citationMoellering, R. C., Graybill, J. R., McGowan, J. E., & Corey, L. (2007) · The American Journal of Medicine · doi:10.1016/j.amjmed.2007.04.001 · Cited by 73 · see citing works
Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
Bow, E. J., Evans, G. A., Fuller, J., Laverdière, M., Rotstein, C., Rennie, R. P., Shafran, S. D., Sheppard, D. C., Carle, S., Phillips, P., et al. (2010) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2010/357076 · Cited by 68 · see citing works
Melhem, M. D. S. C., Bertoletti, A. C. D., Lucca, H., Silva, R., Meneghin, F., & Szeszs, M. (2013) · Brazilian Journal of Microbiology · doi:10.1590/s1517-83822014005000018 · Cited by 62 · see citing works
St‐Germain, G., Laverdière, M., Pelletier, R., René, P., Bourgault, A., Lemieux, C., & Libman, M. (2007) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2008/634046 · Cited by 61 · see citing works
Rautemaa‐Richardson, R., Richardson, M. D., Pfaller, M. A., Koukila-Kähkölä, P., Perheentupa, J., & Saxén, H. (2007) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkm299 · Cited by 59 · see citing works
Self-citationSchmalreck, A., Willinger, B., Haase, G., Blum, G., Lass‐Flörl, C., Fegeler, W., Becker, K., & for the Antifungal Susceptibility Testing (AFST) Study Group (2012) · Mycoses · doi:10.1111/j.1439-0507.2011.02165.x · Cited by 57 · see citing works
Azole‐resistant Candida spp. – emerging pathogens?
Tobudic, S., Kratzer, C., & Presterl, E. (2012) · Mycoses · doi:10.1111/j.1439-0507.2011.02146.x · Cited by 57 · see citing works
Pfaller, M. A., Messer, S. A., Boyken, L. B., Tendolkar, S., Hollis, R. J., & Diekema, D. J. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.01952-07 · Cited by 55 · see citing works
Self-citationPfaller, M. A., Diekema, D. J., Jones, R. N., & Castanheira, M. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.00782-14 · Cited by 51 · see citing works
Self-citationEspinel‐Ingroff, A., Cantón, R., Pemán, J., Rinaldi, M. G., & Fothergill, A. W. (2009) · Journal of Clinical Microbiology · doi:10.1128/jcm.00654-09 · Cited by 49 · see citing works
Isavuconazole, a broad-spectrum triazole for the treatment of systemic fungal diseases
Seyedmousavi, S., Verweij, P. E., & Mouton, J. W. (2014) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2015.990382 · Cited by 47 · see citing works
Castanheira, M., Messer, S. A., Rhomberg, P. R., Dietrich, R. D., Jones, R. N., & Pfaller, M. A. (2014) · Mycopathologia · doi:10.1007/s11046-014-9772-2 · Cited by 46 · see citing works
Self-citationdos Santos, E. R., Forno, C. F. D., Liscano, M. G. H., Kubiça, T. F., Venturini, T. P., Chassot, F., Santurio, J. M., & Alves, S. H. (2014) · Revista do Instituto de Medicina Tropical de São Paulo · doi:10.1590/s0036-46652014000600004 · Cited by 42 · see citing works
Costa, C., Ribeiro, J., Miranda, I. M., Silva-Dias, A., Cavalheiro, M., Costa-de-Oliveira, S., Rodrigues, A. G., & Teixeira, M. C. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00526 · Cited by 43 · see citing works
Johnson, E. M., Espinel‐Ingroff, A., Székely, A., Hockey, H. P., & Troke, P. F. (2008) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2008.05.023 · Cited by 43 · see citing works
In Vitro Susceptibilities of Candida albicans Isolates to Antifungal Agents in Tokat, Turkey
Yenisehirli, G., Bulut, N., Yenisehirli, A., & Bulut, Y. (2015) · Jundishapur Journal of Microbiology · doi:10.5812/jjm.28057 · Cited by 42 · see citing works
Intra-abdominal Sepsis: Newer Interventional and Antimicrobial Therapies
Solomkin, J. S., & Mazuski, J. E. (2009) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2009.04.007 · Cited by 41 · see citing works
Razzaghi‐Abyaneh, M., Sadeghi, G., Zeinali, E., Alirezaee, M., Shams‐Ghahfarokhi, M., Amani, A., Mirahmadi, R., & Tolouei, R. (2014) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2014.01.004 · Cited by 39 · see citing works
Moellering, R. C., Graybill, J. R., McGowan, J. E., & Corey, L. (2007) · American Journal of Infection Control · doi:10.1016/j.ajic.2007.08.001 · Cited by 38 · see citing works
Chong, Y., Ito, Y., Kamimura, T., Shimoda, S., Miyamoto, T., Akashi, K., Yakushiji, H., & Shimono, N. (2012) · Journal of Infection and Chemotherapy · doi:10.1007/s10156-012-0412-9 · Cited by 35 · see citing works
Antifungal Susceptibility of Bloodstream Candida Isolates in Sfax Hospital: Tunisia
Sellami, A., Sellami, H., Néji, S., Makni, F., Abbes, S., Cheikhrouhou, F., Chelly, H., Bouaziz, M., Hammami, B., Jemâa, M. B., et al. (2010) · Mycopathologia · doi:10.1007/s11046-010-9388-0 · Cited by 32 · see citing works
Chen, T., Chen, Y., Chen, Y., & Lu, P. (2012) · The Kaohsiung Journal of Medical Sciences · doi:10.1016/j.kjms.2011.11.011 · Cited by 30 · see citing works
Marcos‐Arias, C., Eraso, E., Madariaga, L., Carrillo‐Muñoz, A. J., & Quindós, G. (2011) · Mycopathologia · doi:10.1007/s11046-011-9460-4 · Cited by 26 · see citing works
Epidemiology of nosocomial candidaemia in a university hospital: a 12-year study
Gürcüoğlu, E., Ener, B., Akalın, H., SINIRTAŞ, M., Evci, C., Akçağlar, S., Yılmaz, E., & Heper, Y. (2010) · Epidemiology and Infection · doi:10.1017/s0950268809991531 · Cited by 25 · see citing works
A global evaluation of voriconazole activity tested against recent clinical isolates of Candida spp.
Diekema, D. J., Messer, S. A., Hollis, R. J., Boyken, L. B., Tendolkar, S., Kroeger, J. S., Jones, R. N., & Pfaller, M. A. (2008) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2008.11.001 · Cited by 25 · see citing works
Self-citationMetin, D. Y., Polat, S. H., Şamlıoğlu, P., Doganay-Oflazoglu, B., İnci, R., & Tümbay, E. (2011) · Mycopathologia · doi:10.1007/s11046-011-9413-y · Cited by 22 · see citing works
Mario, D. A. N., Denardi, L. B., Bandeira, L. A., Antunes, M. S., Santúrio, J. M., Severo, L. C., & Alves, S. H. (2012) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/s0074-02762012000300022 · Cited by 21 · see citing works
Denardi, L. B., Mario, D. A. N., Loreto, É. S., Nogueira, C. W., Santúrio, J. M., & Alves, S. H. (2013) · Mycopathologia · doi:10.1007/s11046-013-9672-x · Cited by 21 · see citing works
Pakshir, K., Zomorodian, K., Zakaei, A., Motamedi, M., Ghiasi, M. R., & Karamitalab, M. (2015) · Current Medical Mycology · doi:10.18869/acadpub.cmm.1.4.26 · Cited by 19 · see citing works
Tratamiento de las infecciones fúngicas en pacientes con neoplasias hematológicas
Mensa, J., de la Cámara, R., Carreras, E., Estrella, M. C., Rodríguez, J. Á. G., Gobernado, M., Picazo, J., Aguado, J. M., & Sanz, M. Á. (2009) · Medicina Clínica · doi:10.1016/j.medcli.2009.01.008 · Cited by 16 · see citing works
Biswas, M., John, S., Jinda, P., & Sukasem, C. (2023) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2023.2203860 · Cited by 15 · see citing works
Hii, I.-M., Liu, C.-E., Lee, Y.-L., Liu, W., Wu, P.-F., Hsieh, M.-H., Ho, M., Chen, Y., & Wang, F. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s184884 · Cited by 15 · see citing works
Structure–activity relationship study of nitrosopyrimidines acting as antifungal agents
Olivella, M. S., Marchal, A., Nogueras, M., Sánchez, A., Melguizo, M., Raimondi, M., Zacchino, S. A., Giannini, F., Cobo, J., & Enriz, R. D. (2012) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2012.08.033 · Cited by 13 · see citing works
Lei, J., Xu, J., & Wang, T. (2018) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2018.03.005 · Cited by 11 · see citing works
Quindós, G., Carrillo‐Muñoz, A. J., Eraso, E., Cantón, E., & Pemán, J. (2007) · Revista Iberoamericana de Micología · doi:10.1016/s1130-1406(07)70043-8 · Cited by 11 · see citing works
New antifungal agents for the treatment of candidaemia
Muñóz, P., Guinea, J., Rojas, L., & Bouza, E. (2010) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2010.11.007 · Cited by 10 · see citing works
Antifungal Activity of the Essential Oil of Echinops kebericho Mesfin: An In Vitro Study
Beressa, T. B., Deyno, S., & Alele, P. E. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/3101324 · Cited by 10 · see citing works
Invasive Fungal Infections and Approaches to Their Diagnosis
Pfaller, M. A. (2015) · Methods in microbiology · doi:10.1016/bs.mim.2015.05.002 · Cited by 10 · see citing works
Self-citationDistribution and antifungal susceptibility of yeasts isolates from intensive care unit patients
Hrabovský, V., Takáčová, V., Schréterová, E., Pastvová, L., Hrabovská, Z., Čurová, K., & Siegfried, L. (2017) · Folia Microbiologica · doi:10.1007/s12223-017-0525-8 · Cited by 10 · see citing works
Nett, J. E., & Andes, D. R. (2014) · ASM Press eBooks · doi:10.1128/9781555817176.ch22 · Cited by 10 · see citing works
New developments in the antifungal susceptibility testing of Candida
Pfaller, M. A. (2008) · Current Fungal Infection Reports · doi:10.1007/s12281-008-0019-x · Cited by 9 · see citing works
Self-citationDam characteristics associated with pre-weaning diarrhea in mink (Neovison vison)
Birch, J. M., Agger, J. F. G., Aalbæk, B., Struve, T., Hammer, A. S., & Jensen, H. E. (2018) · Acta veterinaria Scandinavica · doi:10.1186/s13028-018-0427-z · Cited by 8 · see citing works
Antifungal Susceptibility of Candida albicans Isolates at a Tertiary Care Hospital in Bulgaria
Hitkova, H. Y., Georgieva, D. S., Hristova, P. M., & Sredkova, M. (2019) · Jundishapur Journal of Microbiology · doi:10.5812/jjm.92079 · Cited by 8 · see citing works
Mechanisms of Resistance to Antifungal Agents
Perlin, D. S. (2015) · ASM Press eBooks · doi:10.1128/9781555817381.ch130 · Cited by 7 · see citing works
In vitroactivity of voriconazole against Mexican oral yeast isolates
Vargas, L. O. S., Eraso, E., Carrillo‐Muñoz, A. J., Aguirre, J. M., Gaitán-Cepeda, L. A., & Quindós, G. (2009) · Mycoses · doi:10.1111/j.1439-0507.2009.01702.x · Cited by 7 · see citing works
Shabeer, M., Barbosa, L. C. A., Karak, M., Coelho, A. C. S., & Takahashi, J. A. (2018) · Medicinal Chemistry Research · doi:10.1007/s00044-017-2126-0 · Cited by 5 · see citing works
SPECIES DISTRIBUTION AND ANTIFUNGAL SUSCEPTIBILITY OF YEASTS ISOLATED FROM VAGINAL MUCOSA
Moreira, D., Auler, M. E., Ruiz, L. D. S., da Silva, E. H., Hahn, R. C., & Paula, C. R. (2014) · Revista de Patologia Tropical / Journal of Tropical Pathology · doi:10.5216/rpt.v43i1.29371 · Cited by 6 · see citing works
Biographical Feature: Michael A. Pfaller, M.D
Moser, S. A. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.03125-12 · Cited by 4 · see citing works
Prostatic Abscess With Candida glabrata Treated With Micafungin
Gupta, S., Liu-Young, G., Mahnensmith, R. L., & Topal, J. E. (2008) · Infectious Diseases in Clinical Practice · doi:10.1097/ipc.0b013e31816613f1 · Cited by 3 · see citing works
Jones, R. N., Castanheira, M., & Pfaller, M. A. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00330-10 · Cited by 3 · see citing works
Self-citationDrug susceptibility of Candida isolated from the surfaces of mobile phones and hands
Kordecka, A., Krajewska-Kułak, E., Łukaszuk, C. R., Kraszyński, M., & Kraszyńska, B. (2017) · Progress in Health Sciences · doi:10.5604/01.3001.0010.1861 · Cited by 2 · see citing works
Antifungal Susceptibility of Non-albicans Candida Species in A Tertiary Care Hospital, Bulgaria
Hitkova, H. Y., Georgieva, D. S., Hristova, P. M., Marinova-Bulgaranova, T. V., Borisov, B. K., & Попов, В. Г. (2020) · Jundishapur Journal of Microbiology · doi:10.5812/jjm.101767 · Cited by 2 · see citing works
Andes, D. R., & Dismukes, W. E. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6640-7_5 · Cited by 3 · see citing works
L’albumine endogène : un pouvoir anti-oxydant majeur
Mira, J. P. (2008) · Réanimation · doi:10.1016/s1624-0693(08)73934-3 · Cited by 1 · see citing works
Issues in Anti-infective Management
Forrest, G. N., & Kleinberg, M. E. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-415-5_13
Anidulafungine : une nouvelle option thérapeutique dans les candidoses systémiques
Lanternier, F., & Lortholary, O. (2010) · Médecine et Maladies Infectieuses · doi:10.1016/j.medmal.2009.12.002
Spectrum of Activity, Pharmacology, and Clinical Indications
Nett, J. E., & Andes, D. R. (2015)
- Authors
- Pfaller, M. A., Messer, S. A., Boyken, L., Rice, C., Tendolkar, S., Hollis, R. J., & Diekema, D. J.
- Affiliations
- University of Iowa (US)
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2007-01
- Volume
- 45
- Issue
- 1
- Pages
- 70-75
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- PMC
- PMC1828974
- OpenAlex
- W2148641130
- Cited by
- 77
- References
- 32
- Citations by year
- 2023: 1 · 2020: 2 · 2019: 3 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 7 · 2014: 8 · 2013: 4 · 2012: 7
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Clinical Microbiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Funders
- Pfizer
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Fungal Plant Pathogen Control
- Keywords
- voriconazole, fluconazole, Candida, surrogate markers, antifungal susceptibility testing, triazole antifungals, minimum inhibitory concentration, very major errors, categorical agreement, clinical isolates
- MeSH terms
- Antifungal Agents, Candida, Humans, Laboratories, Microbial Sensitivity Tests, Predictive Value of Tests, Pyrimidines, Reference Standards, Triazoles, Fluconazole, Drug Resistance, Fungal, Voriconazole
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
