The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Identification of a novel rickettsial infection in a patient diagnosed with murine typhus
Open accessAbstract
Identification of ELB agent-infected fleas and rodents within several foci of murine typhus in the United States has prompted a retrospective investigation for this agent among human murine typhus patients. This agent is a recently described rickettsia which is indistinguishable from Rickettsia typhi with currently available serologic reagents. Molecular analysis of the 17-kDa antigen gene and the citrate synthase gene has discriminated this bacterium from other typhus group and spotted fever group rickettsiae. Current sequencing of its 16S ribosomal DNA gene indicates a homology of 98.5% with R. typhi and 99.5% with R. rickettsii. Through a combination of restriction fragment length polymorphism and Southern hybridization analysis of rickettsia-specific PCR products, one of five tested patient blood samples was shown to be infected with ELB while R. typhi infections were confirmed in the remaining samples. This is the first reported observation of a human infection by the ELB agent and underscores the utility of PCR-facilitated diagnosis and discrimination of these closely related rickettsial infections.
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Cites
Amplification of bacterial 16S ribosomal DNA with polymerase chain reaction
Wilson, K. H., Blitchington, R. B., & Greene, R. C. (1990) · Journal of Clinical Microbiology · doi:10.1128/jcm.28.9.1942-1946.1990 · Cited by 647
Phylogenetic diversity of the Rickettsiae
Weisburg, W. G., Dobson, M. E., Samuel, J. E., Dasch, G. A., Mallavia, L. P., Baca, O., Mandelco, L., Sechrest, J. E., Weiss, E., & Woese, C. R. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.8.4202-4206.1989 · Cited by 370
Clinical and Laboratory Features of Murine Typhus in South Texas, 1980 Through 1987
Dumler, J. S. (1991) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1991.03470100057033 · Cited by 258
Self-citationAdams, J. R., Schmidtmann, E. T., & Azad, A. F. (1990) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1990.43.400 · Cited by 195
Self-citationTzianabos, T., Anderson, B. E., & McDade, J. E. (1989) · Journal of Clinical Microbiology · doi:10.1128/jcm.27.12.2866-2868.1989 · Cited by 186
Williams, S. G., Sacci, J. B., Schriefer, M. E., Andersen, E. M., Fujioka, K. K., Sorvillo, F. J., Barr, A. R., & Azad, A. F. (1992) · Journal of Clinical Microbiology · doi:10.1128/jcm.30.7.1758-1762.1992 · Cited by 176
Self-citationDetection of murine typhus infection in fleas by using the polymerase chain reaction
Webb, L., Carl, M., Malloy, D. C., Dasch, G. A., & Azad, A. F. (1990) · Journal of Clinical Microbiology · doi:10.1128/jcm.28.3.530-534.1990 · Cited by 172
Self-citationAzad, A. F., Sacci, J. B., Nelson, W. M., Dasch, G. A., Schmidtmann, E. T., & Carl, M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.1.43 · Cited by 153
Self-citationThe ecology of murine typhus-a critical review.
Traub, R., & Wisseman, C. L. (1978) · PubMed · Cited by 149
Comparative sequence analysis of a genus-common rickettsial antigen gene
ANDERSON, B. E., & Tzianabos, T. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.9.5199-5201.1989 · Cited by 103
Cited by
Rickettsial Pathogens and Their Arthropod Vectors
Azad, A. F., & Beard, C. B. (1998) · Emerging Infectious Diseases · doi:10.3201/eid0402.980205 · Cited by 441
Self-citationFlea-borne Rickettsioses: Ecologic Considerations
Azad, A. F., Radulovic, S., Higgins, J. A., Noden, B. H., & Troyer, J. M. (1997) · Emerging Infectious Diseases · doi:10.3201/eid0303.970308 · Cited by 344
Self-citationEmerging arthropod borne diseases of companion animals in Europe
Beugnet, F., & Marié, J.-L. (2009) · Veterinary Parasitology · doi:10.1016/j.vetpar.2009.03.028 · Cited by 337
Transmission of Flea-Borne Zoonotic Agents
Eisen, R. J., & Gage, K. L. (2012) · Annual Review of Entomology · doi:10.1146/annurev-ento-120710-100717 · Cited by 239
Ecology of Rickettsia felis: A Review
Reif, K. E., & Macaluso, K. R. (2009) · Journal of Medical Entomology · doi:10.1603/033.046.0402 · Cited by 217
Metadata
- Authors
- Schriefer, M. E., Sacci, J. B., Dumler, J. S., Bullen, M. G., & Azad, A. F.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1994-04
- Volume
- 32
- Issue
- 4
- Pages
- 949-954
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W1548849672
- Cited by
- 268
- References
- 16
- FWCI
- 5.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Identification of a novel rickettsial infection in a patient diagnosed with murine typhus. https://app.cochat.ai/papers/10.1128/jcm.32.4.949-954.1994
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- Schriefer, M. E., Sacci, J. B., Dumler, J. S., Bullen, M. G., & Azad, A. F. (1994). Identification of a novel rickettsial infection in a patient diagnosed with murine typhus. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.32.4.949-954.1994
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
