The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Diagnosis of Plasmodium falciparum Malaria at Delivery: Comparison of Blood Film Preparation Methods and of Blood Films with Histology
Open accessAbstract
We compared peripheral and placental blood films (made by different techniques) with placental histology for diagnosis of Plasmodium falciparum malaria in pregnancy. Samples from 464 women were examined, of whom 124 (26.7%) had active P. falciparum infection and 148 (31.9%) had past infection. Placental histology was more sensitive (91%) than peripheral blood film (47%) or placental blood film (63%) examination and also detected past infection. Few women had microscopically detectable infection without a positive histology. Infection detected by histology only and past infection were both associated with significantly lower infant birth weight and with lower hemoglobin concentrations compared to the results for uninfected women. Thick blood films were prepared with blood obtained by placental incision or scraping of the incision margin (263 samples) or by washing of placental tissue (235 samples). Each gave similar sensitivities (76 to 78%), specificities (98 to 99%), positive predictive values (92 to 98%), and negative predictive values (93 to 94%); but the median levels of parasitemia were lower for incision samples (840 parasites/ micro l) than scrapings (2,295 parasites/ micro l) (P = 0.02). Placental histology is the most sensitive method for the diagnosis of malaria in pregnancy. Methods for preparation of placental films may affect the density, but not the prevalence, of P. falciparum infection detected.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In other contexts, satisfactory accuracy parameters have been reported for P. falciparum PM even in low (less than 1000 parasites/µL) and moderate (1000–10,000 parasites/µL) parasitemia, with sensitivity ranging between 76% and 78% [30].”
From Diagnostic Accuracy of a Thick Blood Smear Compared to qPCR for Malaria Associated with Pregnancy in Colombia (2023) · cites this paper as [30]
In the citing paper
“which is novel in this field of research, where evaluations of diagnostic accuracy predominate in areas with a higher frequency of P. falciparum [28,29,30]”
From Diagnostic Accuracy of a Thick Blood Smear Compared to qPCR for Malaria Associated with Pregnancy in Colombia (2023) · cites this paper as [30]
In the citing paper
“Placental histology was also found to be more sensitive than placental BS in several studies, with diagnoses by histology occurring at a rate 1.2–1.7-fold higher than placental BS [16,69–71].”
From Diagnosing malaria in pregnancy: An update (2012) · cites this paper as [70]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Snounou, G., Viriyakosol, S., Zhu, X. P., Jarra, W., Pinheiro, L., do Rosario, V. E., Thaithong, S., & Brown, K. N. (1993) · Molecular and Biochemical Parasitology · doi:10.1016/0166-6851(93)90077-b · Cited by 1,591
Adherence of Plasmodium falciparum to Chondroitin Sulfate A in the Human Placenta
Fried, M., & Duffy, P. E. (1996) · Science · doi:10.1126/science.272.5267.1502 · Cited by 1,108
The burden of malaria in pregnancy in malaria-endemic areas
Steketee, R., Nahlen, B., Parise, M., & Menendez, C. (2001) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2001.64.28 · Cited by 1,063
Parise, M. E., Ayisi, J., Nahlen, B. L., Schultz, L. J., Roberts, J. M., Misore, A. O., Muga, R., Oloo, A. J., & Steketee, R. W. (1998) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1998.59.813 · Cited by 387
Shulman, C. E., Dorman, E. K., Cutts, F. T., Kawuondo, K., Bulmer, J. N., Peshu, N. M., & Marsh, K. (1999) · The Lancet · doi:10.1016/s0140-6736(98)07318-8 · Cited by 386
Adhesion of Plasmodium falciparum-infected erythrocytes to hyaluronic acid in placental malaria
Beeson, J. G., Rogerson, S. J., Cooke, B. M., Reeder, J. C., Chai, W., Lawson, A. M., Molyneux, M. E., & Brown, G. V. (2000) · Nature Medicine · doi:10.1038/71582 · Cited by 310
Self-citationROGERSON, S. J., POLLINA, E., GETACHEW, A., TADESSE, E., LEMA, V. M., & MOLYNEUX, M. E. (2003) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2003.68.1.0680115 · Cited by 275
Self-citationBeeson, J. G., Brown, G. V., Molyneux, M. E., Mhango, C., Dzinjalamala, F., & Rogerson, S. J. (1999) · The Journal of Infectious Diseases · doi:10.1086/314899 · Cited by 266
Self-citationSteketee, R. W., Chilima, B., Chitsulo, L., Bloland, P. B., Breman, J. G., Mermin, J., & Wirima, J. J. (1996) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1996.55.42 · Cited by 258
Placental pathologic changes in malaria. A histologic and ultrastructural study.
Walter, P. R., GARIN, Y. J. F., & Blot, P. (1982) · PubMed · Cited by 253
Guyatt, H., & Snow, R. (2001) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2001.64.36 · Cited by 252
Verhoeff, F. H., Brabin, B. J., Hart, C. A., Chimsuku, L., Kazembe, P. N., & Broadhead, R. (1999) · Tropical Medicine & International Health · doi:10.1046/j.1365-3156.1999.00349.x · Cited by 236
Shulman, C. E., Marshall, T., Dorman, E. K., Bulmer, J. N., Cutts, F., Peshu, N., & Marsh, K. (2001) · Tropical Medicine & International Health · doi:10.1046/j.1365-3156.2001.00786.x · Cited by 182
Rogerson, S. J., Chaluluka, E., Kanjala, M. K., Mkundika, P., Mhango, C. G., & Molyneux, M. E. (2000) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(00)90083-x · Cited by 172
Self-citationGimnig, J. E., KOLCZAK, M. S., Hightower, A. W., VULULE, J. M., Schoute, E., Kamau, L., Phillips‐Howard, P. A., ter Kuile, F. O., Nahlen, B. L., & HAWLEY, W. A. (2003) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2003.68.115 · Cited by 166
Achur, R. N., Valiyaveettil, M., Alkhalil, A., Ockenhouse, C. F., & Gowda, D. C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006398200 · Cited by 165
Leke, R. F. G., Djokam, R. R., Mbu, R., Leke, R. J., Fogako, J., Megnekou, R., Metenou, S., Sama, G., Zhou, Y., Cadigan, T., et al. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.9.2992-2996.1999 · Cited by 118
Diagnosis of Placental Malaria
Mockenhaupt, F. P., Ulmen, U., von Gaertner, C., Bedu-Addo, G., & Bienzle, U. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.1.306-308.2002 · Cited by 108
Malaria and anemia in antenatal women in Blantyre, Malawi: a twelve-month survey.
Rogerson, S. J., van den Broek, N. R., Chaluluka, E., Qongwane, C., Mhango, C., & Molyneux, M. E. (2000) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2000.62.335 · Cited by 107
Self-citationSteketee, R. W., Breman, J. G., Heymann, D. L., Roberts, J. M., Khoromana, C. O., Slutsker, L., & Wirima, J. J. (1996) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1996.55.24 · Cited by 102
Beeson, J. G., Amin, N., Kanjala, M. K., & Rogerson, S. J. (2002) · Infection and Immunity · doi:10.1128/iai.70.10.5412-5415.2002 · Cited by 79
Self-citationMalaria chemoprophylaxis, infection of the placenta and birth weight in Gambian primigravidae.
Menéndez, C., Todd, J., Alonso, P. L., Lulat, S., Francis, N. A., & Greenwood, B. M. (1994) · PubMed · Cited by 68
Mankhambo, L., Kanjala, M., Rudman, S., Lema, V. M., & Rogerson, S. J. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.1.155-158.2002 · Cited by 65
Self-citationPlasmodium falciparum Rosette Formation Is Uncommon in Isolates from Pregnant Women
Rogerson, S. J., Beeson, J. G., Mhango, C. G., Dzinjalamala, F. K., & Molyneux, M. E. (2000) · Infection and Immunity · doi:10.1128/iai.68.1.391-393.2000 · Cited by 33
Self-citationPlasmodium falciparum persists in the placenta after three days' treatment with quinine
Sartelet, H., Milko-Sartelet, I., Garraud, O., & Picot, S. (1997) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(97)90269-8 · Cited by 14
Cited by
Sorted by citations
The Sick Placenta—The Role of Malaria
Brabin, B. J., Romagosa, C., Abdelgalil, S., Menéndez, C., Verhoeff, F. H., McGready, R. M., Fletcher, K. A., Owens, S., d'Alessandro, U., Nosten, F. H., et al. (2004) · Placenta · doi:10.1016/j.placenta.2003.10.019 · Cited by 382
Malaria in Pregnancy: Linking Immunity and Pathogenesis to Prevention
Rogerson, S. J., Mwapasa, V., & Meshnick, S. R. (2007) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.77.6.suppl.14 · Cited by 187
Self-citationMalaria in pregnancy and the endemicity spectrum: what can we learn?
Nosten, F. H., Rogerson, S. J., Beeson, J. G., McGready, R. M., Mutabingwa, T. K., & Brabin, B. J. (2004) · Trends in Parasitology · doi:10.1016/j.pt.2004.06.007 · Cited by 184
Self-citationMaternal Malaria and Gravidity Interact to Modify Infant Susceptibility to Malaria
Mutabingwa, T. K., Bolla, M. C., Li, J., Domingo, G. J., Li, X., Fried, M., & Duffy, P. E. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020407 · Cited by 178
Menéndez, C., Bardají, A., Sigauque, B., Romagosa, C., Sanz, S., Serra-Casas, E., Macete, E., Berenguera, A., David, C., Dobaño, C., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001934 · Cited by 166
Metadata
- Authors
- Rogerson, S. J., Mkundika, P., & Kanjala, M. K.
- Affiliations
- The Royal Melbourne Hospital (AU)
- University of Malawi (MW)
- Corresponding author
- Rogerson, Stephen J.
- ORCID
- Rogerson, Stephen J.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2003-04
- Volume
- 41
- Issue
- 4
- Pages
- 1370-1374
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- PMC
- PMC153918
- OpenAlex
- W2144700918
- Cited by
- 113
- References
- 25
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 7 · 2019: 5 · 2017: 7 · 2016: 7 · 2015: 2 · 2014: 11 · 2013: 5 · 2012: 8
- FWCI
- 5.43
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Microbiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust (046012)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Health Sciences › Medicine › Genetics (clinical) › Hemoglobinopathies and Related Disorders
- Life Sciences › Immunology and Microbiology › Parasitology › Bird parasitology and diseases
- Keywords
- Plasmodium falciparum, malaria in pregnancy, placental histology, peripheral blood smear, parasitemia, birth weight, maternal hemoglobin, diagnostic sensitivity
- MeSH terms
- Animals, Blood, Blood Specimen Collection, Female, Humans, Infant, Low Birth Weight, Infant, Newborn, Placenta, Placenta Diseases, Plasmodium falciparum, Pregnancy, Sensitivity and Specificity, Pregnancy Complications, Parasitic, Malaria, Falciparum, Parasitemia, Delivery, Obstetric
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
