The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Nucleotide sequence and genome organization of human parvovirus B19 isolated from the serum of a child during aplastic crisis
Open accessAbstract
The nucleotide sequence of an almost-full-length clone of human parvovirus B19 was determined. Whereas the extreme left and right ends of this genomic clone are incomplete, the sequence clearly indicates that the two ends of viral DNA are related by inverted terminal repeats similar to those of the Dependovirus genus. The coding regions are complete in the cloned DNA, and the two large open reading frames which span almost the entire genome are restricted to one strand, as has been found for all other parvoviruses characterized to date. From the DNA sequence we conclude that the organization of the B19 transcription units is similar although not identical to those of other parvoviruses. In particular, we predict that the B19 genome may utilize a fourth promoter to transcribe mRNA encoding the major structural polypeptide, VP2. Analysis of the putative polypeptides confirms that B19 is only distantly related to the other parvoviruses but reveals that there is a small region in the gene probably encoding the major nonstructural protein of B19, which is closely conserved between all of the parvovirus genomes for which sequence information is currently available.
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Cites
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PARVOVIRUS-LIKE PARTICLES IN HUMAN SERA
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Nucleotide sequence and organization of the adeno-associated virus 2 genome
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Self-citation
Cited by
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Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein
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The Autonomously Replicating Parvoviruses of Vertebrates
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Metadata
- Authors
- Shade, R. O., Blundell, M. C., Cotmore, S. F., Tattersall, P., & Astell, C. R.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1986-06
- Volume
- 58
- Issue
- 3
- Pages
- 921-936
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- OpenAlex
- W1480400711
- Cited by
- 433
- References
- 29
- FWCI
- 19.21
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Nucleotide sequence and genome organization of human parvovirus B19 isolated from the serum of a child during aplastic crisis. https://app.cochat.ai/papers/10.1128/jvi.58.3.921-936.1986
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- Shade, R. O., Blundell, M. C., Cotmore, S. F., Tattersall, P., & Astell, C. R. (1986). Nucleotide sequence and genome organization of human parvovirus B19 isolated from the serum of a child during aplastic crisis. Journal of Virology. https://doi.org/10.1128/jvi.58.3.921-936.1986
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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