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A Grad-seq View of RNA and Protein Complexes in Pseudomonas aeruginosa under Standard and Bacteriophage Predation Conditions
Open accessPublished version of a preprint
Abstract
Stable complexes by cellular proteins and RNA molecules lie at the heart of gene regulation and physiology in any bacterium of interest. It is therefore crucial to globally determine these complexes in order to identify and characterize new molecular players and regulation mechanisms.
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Global quantification of mammalian gene expression control
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“For protein quantitation, the intensity-based absolute quantification (iBAQ) intensities were used (104).”
MethodThe External RNA Controls Consortium: a progress report
The External RNA Controls Consortium (2005) · Nature Methods · doi:10.1038/nmeth1005-731 · Cited by 373
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Metadata
- Authors
- Gerovac, M., Wicke, L., Chihara, K., Schneider, C., Lavigne, R., & Vogel, J.
- Affiliations
- University of Würzburg (DE)
- Helmholtz Centre for Infection Research (DE)
- KU Leuven (BE)
- Corresponding author
- Lavigne, Rob
- Vogel, Jörg
- Venue
- mBio
- Publisher
- American Society for Microbiology
- Published
- 2021-02-23
- Volume
- 12
- Issue
- 1
- ISSN
- 2150-7511 (ISSN-L)
- 2161-2129
- PMC
- PMC8545117
- OpenAlex
- W3128693665
- Cited by
- 40
- References
- 2
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 7 · 2023: 5 · 2022: 13 · 2021: 6
- FWCI
- 4.19
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- mBio (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Lirias (acceptedVersion, other-oa)
- Lirias (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Online Publication Service of Würzburg University (Würzburg University) (submittedVersion, cc-by)
- HZI (Helmholtz Centre for Infection Research) (submittedVersion, cc-by)
- Funders
- European Commission (HORIZON2020, 819800)
- Deutsche Forschungsgemeinschaft (Vo875, Vo875/18)
- Fonds Wetenschappelijk Onderzoek (11D8920N, 819800)
- Gottfried Wilhelm Leibniz Universität Hannover (DFG Vo875/18)
- Bayerisches Staatsministerium für Wirtschaft und Medien, Energie und Technologie (0703/89374/3/2017, 0703/68674/5/2017 and 0703/89374/3/2017, 0703/68674/5/2017)
- Leibniz-Gemeinschaft
- Topics
- Life Sciences › Immunology and Microbiology › Virology › Bacteriophages and microbial interactions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Keywords
- Pseudomonas aeruginosa, phage infection, phage predation, protein-RNA complex, ribosome profiling, specialized translation, phage-host interactions, physiological stress response
- MeSH terms
- Animals, Bacterial Proteins, Pseudomonas aeruginosa, Ribosomes, RNA, Bacterial, RNA, Messenger, RNA, Transfer, Mass Spectrometry, Gene Expression Regulation, Bacterial, RNA-Binding Proteins, Pseudomonas Phages, RNA, Untranslated
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