Cyr61, a Product of a Growth Factor-Inducible Immediate-Early Gene, Promotes Cell Proliferation, Migration, and Adhesion
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- The immediate early gene product hCYR61 localizes to the secretory pathway in human osteoblastsA Lechner, Norbert Schütze, Heide Siggelkow, Jochen Seufert, Franz Josef Jakob · 2000 · Bone
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- Matrix-bound Cyr61/CCN1 is required to retain the properties of the bone marrow mesenchymal stem cell niche but is depleted with agingMilos Marinkovic, Qiuxia Dai, Aaron O. Gonzalez, Olivia N. Tran, Travis Jackson Block, Stephen E. Harris, Adam B. Salmon, Chih‐Ko Yeh, David D. Dean, Xiao‐Dong Chen · 2022 · Matrix Biology
- Establishment of Cell Lines with High‐ and Low‐metastatic Potential from PC‐14 Human Lung AdenocarcinomaNobuko Shindo‐Okada, Kaori Takeuchi, Yasuhiro Nagamachi · 2001 · Japanese Journal of Cancer Research
- Expression profiling of cardiovascular diseaseStephen R. Archacki, Qing Kenneth Wang · 2004 · Human Genomics
- Simvastatin downregulates adipogenesis in 3T3-L1 preadipocytes and orbital fibroblasts from Graves’ ophthalmopathy patientsBushra Shahida, P Sahlstrand Johnson, R Jain, Håkan Brorson, Peter Åsman, Mikael Lantz, Tereza Planck · 2019 · Endocrine Connections
- CYR61/CCN1 stimulates proliferation and differentiation of osteoblasts in vitro and contributes to bone remodelling in vivo in myeloma bone diseaseHui Liu, Fengping Peng, Zhaoyun Liu, Fengjuan Jiang, Lijuan Li, Shan Gao, Guojin Wang, Jia Song, Erbao Ruan, Zonghong Shao et al. · 2016 · International Journal of Oncology
- IRES-based Vector Coexpressing FGF2 and Cyr61 Provides Synergistic and Safe Therapeutics of Lower Limb IschemiaAudrey Rayssac, Charles Neveu, Mélanie Pucelle, Loïc Van Den Berghe, Leonel Prado-Lourenço, Jean‐François Arnal, Xavier Chaufour, Anne‐Catherine Prats · 2009 · Molecular Therapy
- A global genomic view of MIF knockdown-mediated cell cycle arrestLingfeng Liu, Chaoneng Ji, Jinzhong Chen, Yao Li, Xuping Fu, Yi Xie, Shaohua Gu, Yumin Mao · 2008 · Cell Cycle
- Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding–epidermal growth factor and cystein-rich angiogenic inducer 61 expressionSilvia D’Ippolito, Fiorella Di Nicuolo, Riccardo Marana, Roberta Castellani, John C. Stinson, Chiara Tersigni, Giovanni Scambia, Nicoletta Di Simone · 2012 · Fertility and Sterility
- Serum Cyr61 is Associated With Clinical Disease Activity and Inflammation in Patients With Systemic Lupus ErythematosusJinpiao Lin, Ningli Li, Huijuan Chen, Can Liu, Bin Yang, Qishui Ou · 2015 · Medicine
- CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone diseaseSadie Johnson, Peter Stewart, Rakesh Bam, Pingping Qu, Bart Barlogie, Frits van Rhee, John D. Shaughnessy, Joshua Epstein, Shmuel Yaccoby · 2014 · Blood
- Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell outputYalin Emre, Magali Irla, Isabelle Dunand-Sauthier, Romain Ballet, Mehdi Meguenani, Stéphane Jemelin, Christian Vesin, Walter Reith, Beat A. Imhof · 2013 · Nature Communications
- CCN1 triggers adaptive autophagy in cardiomyocytes to curb its apoptotic activitiesBor‐Chyuan Su, Pei‐Ling Hsu, Fan‐E Mo · 2019 · Journal of Cell Communication and Signaling
- Matricellular Protein Cyr61 Bridges Lysophosphatidic Acid and Integrin Pathways Leading to Cell MigrationDaniel Dongwei Wu, Fuqiang Zhang, Hao Feng, Jerold J. M. Chun, Xuemin Xu, Mei‐Zhen Cui · 2013 · Journal of Biological Chemistry
- Chromosomal mapping and expression of the human cyr61 gene in tumour cells from the nervous system.C. Martinerie, E. Viégas-Pèquignot, V.C. Nguyen, Bernard Perbal · 1997 · Molecular Pathology
- The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitroAntonia Bär, S. E. Dorfman, Philipp Fischer, Denise Hilfiker‐Kleiner, Serghei Cebotari, I. Tudorache, Mark Suprunov, Axel Haverich, Andres Hilfiker · 2009 · Cardiovascular Research
- The Angiogenic Factor Cyr61 Is Induced by the Progestin R5020 and Is Necessary for Mammary Adenocarcinoma Cell GrowthDeepak Sampath, Richard C. Winneker, Zhiming Zhang · 2002 · Endocrine
- Association of BTG2, CYR61, ZFP36 , and SCD Gene Polymorphisms with Graves' Disease and OphthalmopathyTereza Planck, Bushra Shahida, Marketa Sjögren, Leif Groop, Bengt Hallengren, Mikael Lantz · 2014 · Thyroid
- Expression of immediate early gene cyr61 during the differentiation of immortalized embryonic hippocampal neuronal cellsKwang Chul Chung, Young Soo Ahn · 1998 · Neuroscience Letters
- Extracellular matrix protein CCN1 regulates cardiomyocyte apoptosis in mice with stress-induced cardiac injuryPei‐Ling Hsu, B.-C. Su, Qian-Yu Kuok, Fan‐E Mo · 2013 · Cardiovascular Research
- Identification of Cysteine‐Rich Angiogenic Inducer 61 as a Potential Antifibrotic and Proangiogenic Mediator in SclerodermaPei‐Suen Tsou, Dinesh Khanna, Amr H. Sawalha · 2019 · Arthritis & Rheumatology
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- Insights into the Effects of the Dental Stem Cell Secretome on Nerve Regeneration: Towards Cell-Free TreatmentRohaina Che Man, Nadiah S Sulaiman, Ruszymah Bt Hj Idrus, Shahrul Hisham Zainal Ariffin, Rohaya Megat Abdul Wahab, Muhammad Dain Yazid · 2019 · Stem Cells International
- The repairing effect of a recombinant human connective‐tissue growth factor in a burn‐wounded rhesus‐monkey (Macaca mulatta) modelLongding Liu, Hai‐jing Shi, Li Jiang, Li‐chun Wang, Shaohui Ma, Chenghong Dong, Jingjing Wang, Hong‐ling Zhao, Yun Liao, Qi‐han Li · 2007 · Biotechnology and Applied Biochemistry
- Invasion and increased expression of S100A4 and CYR61 in mesenchymal transformed breast cancer cells is downregulated by GnRHCarsten Gründker, Gerd Johannes Bauerschmitz, Antje Schubert, Günter Emons · 2016 · International Journal of Oncology
- Coatings in Decellularized Vascular Scaffolds for the Establishment of a Functional Endothelium: A Scoping Review of Vascular Graft RefinementJun Wei Heng, Muhammad Dain Yazid, Mohd Ramzisham Abdul Rahman, Nadiah S Sulaiman · 2021 · Frontiers in Cardiovascular Medicine
- CCN6 as a profibrotic mediator that stimulates the proliferation of lung fibroblasts via the integrin .BETA.1/focal adhesion kinase pathwayRentsenkhand Batmunkh, Yasuhiko Nishioka, Yoshinori Aono, Momoyo Azuma, Katsuhiro Kinoshita, Jun Kishi, Hideki Makino, Masami Kishi, Akio Takezaki, Saburo Sone · 2011 · The Journal of Medical Investigation
- Decidual Cells Produce a Heparin-binding Prolactin Family Cytokine with Putative Intrauterine Regulatory ActionsS. M. Khorshed Alam, Toshihiro Konno, Namita Sahgal, Lu Lu, Michael J. Soares · 2008 · Journal of Biological Chemistry
- Simvastatin Inhibits CYR61 Expression in Orbital Fibroblasts in Graves’ Ophthalmopathy through the Regulation of FoxO3a SignalingYi‐Hsuan Wei, Shu‐Lang Liao, Chia‐Chun Wang, Sen-Hsu Wang, Wanchun Tang, Chang‐Hao Yang · 2021 · Mediators of Inflammation
- Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cellsXu · 2011 · International Journal of Molecular Medicine
- Regulation of Cell Behavior by Extracellular ProteinsAmy D. Bradshaw · 2013 · Elsevier eBooks
- Hypoxia-Induced Cyr61/CCN1 Production in Infantile HemangiomaPinru Wu, Hui Xu, Ningli Li, Rongfen Huo, Baihua Shen, Xiaoxi Lin, Gang Ma · 2021 · Plastic & Reconstructive Surgery
- Differences in gene expression between noninvasive and invasive transitional cell carcinoma of the human bladder using complementary deoxyribonucleic acid microarray: Preliminary resultsEssam Elsamman, Tomoharu Fukumori, Ashraf A. Ewis, Nermin Ali, Kazuaki Kajimoto, Yasuo Shinohara, Mitsuru Ishikawa, Masayuki Takahashi, Masaaki Nishitani, Yoshinobu Baba et al. · 2006 · Urologic Oncology Seminars and Original Investigations
- The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cellsJavier Abel Menéndez, Luciano Vellón, Ingrid C. Espinoza, Ruth Lupu · 2016 · Oncoscience
- Factor VIIa-Induced Gene ExpressionL. Vijaya Mohan Rao, Usha R. Pendurthi · 2001 · Trends in Cardiovascular Medicine
- Organization and Expression of the Cyr61 Gene in Normal Human FibroblastsEsther C. Leng, Tom Malcolm, Georgia Tai, Mario Clemente Estable, Ivan Sadowski · 2002 · Journal of Biomedical Science
- Proteome Changes Induced by Expression of Tumor Suppressor PTENSo-yeon Kim, Yu Sam Kim, Young Yil Bahk · 2003 · Molecules and Cells
- Gα 12/13 Induction of CYR61 in Association With Arteriosclerotic Intimal Hyperplasia: Effect of Sphingosine-1-PhosphateKim, Young Mi, Lim, Sung-Chul, Han, Chang Yeob, Kay, Hee Yeon, Cho, Il Je, Ki, Sung Hwan, Lee, Moo Yeol, Kwon, Hyuck Moon, Lee, Chang Ho, Kim, Sang Geon · 2011 · Arteriosclerosis, Thrombosis, and Vascular Biology
- Plasminogen Regulates Fracture Repair by Promoting the Functions of Periosteal Mesenchymal ProgenitorsLuqiang Wang, Lutian Yao, Hao Duan, Fan Yang, Maohuan Lin, Rongxin Zhang, Zhenqiang He, Jaimo Ahn, Yi Fan, Ling Qin et al. · 2021 · Journal of Bone and Mineral Research
- Effects of schizophrenomimetics on the expression of the CCN1 (CYR 61) gene encoding a matricellular protein in the infant and adult neocortex of the mouse and ratTakashi Ito, Shuichi Hiraoka, Yasukazu Kuroda, Sumikazu Ishii, Asami Umino, Atsushi Kashiwa, Naoki Yamamoto, Akeo Kurumaji, Toru Nishikawa · 2007 · The International Journal of Neuropsychopharmacology
- Cysteine-rich 61 (CYR61) inhibits cisplatin-induced apoptosis in ovarian carcinoma cellsSeung Bae Rho, Hyun‐Jung Byun, Sang‐Yoon Park, Taehoon Chun · 2008 · Biotechnology Letters
- Human connective tissue growth factor expressed in Escherichia coli is a non-mitogenic inhibitor of apoptosisDaniel Gygi, Peter Zumstein, Doris Grossenbacher, Lukas Andreas Altwegg, Thomas Felix Lüscher, Heinz Gehring · 2003 · Biochemical and Biophysical Research Communications
- Nephroblastoma overexpressed gene (NOV) expression in rat hepatic stellate cellsSung Hee Lee, Geom Seog Seo, Young Nyun Park, Dong Hwan Sohn · 2004 · Biochemical Pharmacology
- Vascular repair and anti-inflammatory effects of soluble epoxide hydrolase inhibitorNa Dai, Cui-Fen Zhao, Q. Kong, Dong Li, Zhi-Feng Cai, Minmin Wang · 2019 · Experimental and Therapeutic Medicine
- Identification of G1-Regulated Genes in Normally Cycling Human CellsMaroun J. Beyrouthy, Karen E. Alexander, Amy E. Baldwin, Michael L. Whitfield, Hank W. Bass, Dan McGee, Myra M. Hurt · 2008 · PLoS ONE
- Matricellular protein CCN1 (CYR61) expression is associated with high-grade ductal carcinoma in situOzlen Saglam, Feng Dai, Seema Husain, Yilei Zhan, Gökçe Törüner, G. Kenneth Haines · 2014 · Human Pathology
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- A Role for Cysteine-Rich 61 in the Angiogenic Switch During the Estrous Cycle in Cows: Regulation by Prostaglandin F2alpha1Bo Zhang, Paul C. W. Tsang, Joy L. Pate, Marsha A. Moses · 2011 · Biology of Reproduction
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- CCN1 secreted by human adipose‐derived stem cells enhances wound healing and promotes angiogenesis through activating the AKT signalling pathwayYi Yang, Shiyi Li, Xuer Sun, Lixia Zhang, Minliang Chen, Huijuan Fu · 2022 · International Wound Journal
- Development of Quantitative Detection Assays for CYR61 as a New Marker for Benign Prostatic HyperplasiaShinji Sakamoto, Masahiro Yokoyama, Prakash Kulkarni, Jun-Ichiro Tsuruha, Satoshi Masamoto, Robert H. Getzenberg, Yoshiyuki Kakehi · 2003 · SLAS DISCOVERY
- Cysteine-rich matricellular protein improves callus regenerate in a rabbit trauma modelSoenke Percy Frey, Stefanie Hoelscher‐Doht, Lars Eden, Stefan Dannigkeit, Norbert Schütze, Rainer Heribert Meffert, Hendrik Jansen · 2012 · International Orthopaedics
- Occlusal Hypofunction Induces Atrophic Changes in Rat GingivaYuji Ishida, Zuisei Kanno, Kunimichi Soma · 2008 · The Angle Orthodontist
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- Activation of Mechanosensitive Transcription Factors in Murine C2C12 Mesenchymal Precursors by Focused Low-Intensity Pulsed Ultrasound (FLIPUS)Regina Puts, Paul Rikeit, Karen Ruschke, Anke Kadow‐Romacker, Soyoung Hwang, Klaus‐Vitold Jenderka, Petra I. Knaus, Kay Raum · 2016 · IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control
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- Cysteine‐rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signalingYongxu Yang, Qi Qi, Yi Wang, Yaru Shi, Weili Yang, Yunzhu Cen, Endong Zhu, Xiaoxia Li, Di Chen, Baoli Wang · 2018 · The FASEB Journal
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- The Effect of Hydrolyzed Jeju Ulva pertusa on the Proliferation and Type I Collagen Synthesis in Replicative Senescent FibroblastsHyun Ju Ko, Gyoung Bum Kim, Dong Hwan Lee, Geun Soo Lee, Hyeong-Bae Pyo · 2013 · Journal of the Society of Cosmetic Scientists of Korea
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- Isolation of a Novel Actin-Related Gene Expressed in Low-Metastatic PC-14 Human Lung AdenocarcinomaNobuko Shindo‐Okada, Kimihiro Shimizu · 2001 · Biochemical and Biophysical Research Communications
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