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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes

Open access
Theis, Kevin R., Dheilly, Nolwenn M., Klassen, Jonathan L., Brucker, Robert M., Baines, John F., Bosch, Thomas C. G., Cryan, John F., Gilbert, Scott F., Goodnight, Charles J., Lloyd, Elisabeth A., Sapp, Jan, Vandenkoornhuyse, Philippe, Zilber-Rosenberg, Ilana, Rosenberg, Eugene, Bordenstein, Seth R.·2016·mSystems

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Abstract

Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization—what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or limited to a certain spectrum of symbiotic interactions such as host-microbial coevolution? Critical discourse is necessary in this nascent area, but productive discourse requires that skeptics and proponents use the same lexicon.

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Research works printed but not linked: 30

  1. Rosenberg E Zilber-Rosenberg I . 2013. The hologenome concept: human animal and plant microbiota. Springer Basel Switzerland. · DOI
  2. Margulis L . 1991. Symbiogenesis and symbionticism, p 1–14. InMargulisLFesterR (ed), Symbiosis as a source of evolutionary innovation: speciation and morphogenesis. MIT Press, Cambridge, MA.
  3. 10.1016/0303-2647(92)90046-2 · DOI
  4. 10.1128/microbe.8.152.1 · DOI
  5. 10.1128/IAI.02627-14 · DOI
  6. 10.1371/journal.pbio.1002311 · DOI · Paper page
  7. 10.1111/nph.13312 · DOI · Paper page
  8. 10.1073/pnas.1218525110 · DOI · Paper page
  9. 10.1016/j.zool.2011.04.001 · DOI · Paper page
  10. 10.1016/j.tim.2015.07.009 · DOI · Paper page
  11. 10.3389/fmicb.2015.00697 · DOI
  12. 10.1038/ismej.2015.190 · DOI
  13. 10.1126/science.1251997 · doi:10.1126/science.1251997
  14. 10.3389/fmicb.2014.00046 · DOI
  15. 10.1126/science.1240659 · DOI · Paper page
  16. 10.1073/pnas.0703375104 · DOI · Paper page
  17. 10.1111/j.1558-5646.2011.01454.x · DOI · Paper page
  18. 10.1016/j.tree.2012.03.011 · DOI · Paper page
  19. 10.1073/pnas.1304960110 · DOI · Paper page
  20. 10.1111/nph.12150 · DOI · Paper page
  21. 10.1038/nrg1877 · DOI · Paper page
  22. 10.1111/j.0014-3820.2006.tb01177.x · DOI · Paper page
  23. 10.1126/science.aab3958 · DOI
  24. 10.1111/j.1461-0248.2005.00844.x · DOI · Paper page
  25. 10.1098/rstb.2010.0290 · DOI
  26. 10.1111/j.1758-2229.2010.00177.x · DOI · Paper page
  27. 10.1002/bdrc.20196 · DOI · Paper page
  28. 10.1111/j.1462-2920.2009.01995.x · DOI · Paper page
  29. 10.1016/j.meegid.2015.05.027 · DOI
  30. Lloyd EA . Holobionts as units of selection: holobionts as interactors, reproducers, and manifestors of adaptation. InGissisSBLammEShavitA (ed), Landscapes of collectivity in the life sciences, in press. MIT Press, Cambridge, MA.

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Metadata

Authors
Theis, K. R., Dheilly, N. M., Klassen, J. L., Brucker, R. M., Baines, J. F., Bosch, T. C. G., Cryan, J. F., Gilbert, S. F., Goodnight, C. J., Lloyd, E. A., Sapp, J., Vandenkoornhuyse, P., Zilber-Rosenberg, I., Rosenberg, E., & Bordenstein, S. R.
Venue
mSystems
Published
2016-04-26
Volume
1
Issue
2
ISSN
2379-5077 (ISSN-L)
OpenAlex
W2949512018
Cited by
567
References
3
FWCI
44.52
Type
journal article
Language
en
Open access
gold
Licence

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CoChat. (2026). Citation check: Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes. https://app.cochat.ai/papers/10.1128/msystems.00028-16
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Theis, K. R., Dheilly, N. M., Klassen, J. L., Brucker, R. M., Baines, J. F., Bosch, T. C. G., Cryan, J. F., Gilbert, S. F., Goodnight, C. J., Lloyd, E. A., Sapp, J., Vandenkoornhuyse, P., Zilber-Rosenberg, I., Rosenberg, E., & Bordenstein, S. R. (2016). Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes. mSystems. https://doi.org/10.1128/msystems.00028-16

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.