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Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling
Open accessAbstract
While the ability for humans to host a complex microbial ecosystem is an essential property of life, the mechanisms allowing for immune tolerance of such a large microbial load are not completely understood and are currently the focus of intense research. This study shows that an important proinflammatory pathway that is commonly triggered by pathogenic bacteria upon interaction with the host is, in fact, actively repressed by the bacteria of the gut microbiome, supporting the idea that beneficial microbes themselves contribute to the immune tolerance in support of homeostasis. These findings are important for two reasons. First, many currently assume that proinflammatory signaling by lipopolysaccharide is a fundamental feature of the gut flora. This assumption influences greatly how host-microbiome interactions are theoretically modeled but also how they are experimentally studied, by using robust TLR signaling conditions to simulate commensals. Second, elucidation of the mechanisms that support host-microbe tolerance is key to the development of therapeutics for both intestinal and systemic inflammatory disorders.
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“In the gut, LPS-TLR4 signalling has been shown to both dampen intestinal immune responses to the resident microbiota during states of health5”
From Gut microbiota-derived hexa-acylated lipopolysaccharides enhance cancer immunotherapy responses (2025) · cites this paper as [5]
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Cites
Fast gapped-read alignment with Bowtie 2
Langmead, B., & Salzberg, S. L. (2012) · Nature Methods · doi:10.1038/nmeth.1923 · Cited by 56,400
Fast and sensitive protein alignment using DIAMOND
Buchfink, B., Xie, C., & Huson, D. H. (2015) · Nature Methods · doi:10.1038/nmeth.3176 · Cited by 14,201
Structure, function and diversity of the healthy human microbiome
The Human Microbiome Project Consortium (2012) · Nature · doi:10.1038/nature11234 · Cited by 11,726
A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624
Diversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913
Changes of Intestinal Functions in Liver Cirrhosis
Fukui, H., & Wiest, R. (2016) · Inflammatory Intestinal Diseases · doi:10.1159/000444436 · Cited by 6,820
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
Donlan, R. M., & Costerton, J. W. (2002) · Clinical Microbiology Reviews · doi:10.1128/cmr.15.2.167-193.2002 · Cited by 6,644
Metabolic Endotoxemia Initiates Obesity and Insulin Resistance
Cani, P. D., Amar, J., Iglesias, M. A., Poggi, M., Knauf, C., Bastelica, D., Neyrinck, A. M., Fava, F., Tuohy, K. M., Chabo, C., et al. (2007) · Diabetes · doi:10.2337/db06-1491 · Cited by 6,638
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549
The gut microbiota shapes intestinal immune responses during health and disease
Round, J. L., & Mazmanian, S. K. (2009) · Nature Reviews Immunology · doi:10.1038/nri2515 · Cited by 5,029
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Items 201–300 of 326
Exploring the Diet-Gut Microbiota-Epigenetics Crosstalk Relevant to Neonatal Diabetes
Alsharairi, N. A. (2023) · Genes · doi:10.3390/genes14051017 · Cited by 11
Shahbazi, R., Yasavoli‐Sharahi, H., Mallet, J., Sharifzad, F., Alsadi, N., Cuenin, C., Cahais, V., Chung, F. F., Herceg, Z., & Matar, C. (2023) · Microorganisms · doi:10.3390/microorganisms11102456 · Cited by 10
Understanding Aging through the Lense of Gut Microbiome
Ira, R., Adwani, J., Krishnan, A. O., Subramanian, G., Yadav, S., Shukla, S., Rao, S., & Prakash, T. (2024) · Exploratory Research and Hypothesis in Medicine · doi:10.14218/erhm.2024.00008 · Cited by 9
Exploring potential associations between the human microbiota and reservoir of latent HIV
Marín, N., Paredes, R., & Borgognone, A. (2024) · Retrovirology · doi:10.1186/s12977-024-00655-w · Cited by 10
Zhang, L., Tian, G., Huang, L., Zhou, M., Zhu, J., Yi, L., & Mi, M. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.965180 · Cited by 12
Faraj, T. A., Stover, C. M., & Erridge, C. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01404 · Cited by 10
Sardelli, L., Campanile, M., Boeri, L., Donnaloja, F., Fanizza, F., Perottoni, S., Petrini, P., Albani, D., & Giordano, C. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100898 · Cited by 10
Wang, Z., Ojogun, N., Liu, Y., Gan, L., Xiao, Z., Feng, J., Jiang, W., Chen, Y., Zou, B., Yu, C., et al. (2024) · eLife · doi:10.7554/elife.100731 · Cited by 17
Oyovwi, M. O., Joseph, G. U., Oyekanmi, B. A., Odokuma, E. I., & Ogenma, U. T. (2024) · OBM Neurobiology · doi:10.21926/obm.neurobiol.2404254 · Cited by 10
An in vitro intestinal model captures immunomodulatory properties of the microbiota in inflammation
Lock, J. Y., Caboni, M., Strandwitz, P., Morrissette, M., DiBona, K. C., Joughin, B. A., Lewis, K., & Carrier, R. L. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2039002 · Cited by 9
Li, Y., Xu, M., Zhai, H., Yang, C., Yang, J., Ke, Z., Chen, W., Ou, J., Sha, Z., & Xiao, Q. (2023) · Molecular Medicine Reports · doi:10.3892/mmr.2023.13082 · Cited by 9
Alistipes: The influence of a commensal on anxiety and depression
Dhaliwal, G. K. (2019) · Cited by 9
Gut Microbiome Signatures Linked to HIV-1 Reservoir Size and Viremia ControlPreprint
Borgognone, A., Noguera-Julián, M., Oriol-Tordera, B., Noël‐Romas, L., Ruiz‐Riol, M., Guillén, Y., Parera, M., Casadellà, M., Duran-Castells, C., Puertas, M. C., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.03.462590 · Cited by 9
The gut microbiome as a modulator of arterial function and age-related arterial dysfunction
Longtine, A. G., Greenberg, N., de Quirós, Y. B., & Brunt, V. E. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00764.2023 · Cited by 9
Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care
Lee, S., Wischmeyer, P. E., Mintz, C. D., & Serbanescu, M. A. (2024) · Critical Care Clinics · doi:10.1016/j.ccc.2024.11.002 · Cited by 11
Liao, J., Zhou, Z., Lv, Y., Zhang, Y., Liu, S., Tang, H., Qv, F., Wang, S., Yang, L., Lu, Y., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1667180 · Cited by 8
Sarkar, K., & Sil, P. C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85215-9.00007-6 · Cited by 8
Metabolic endotoxemia: possible causes and consequences
Beloglazov, V. A., Yatskov, I. A., Кумельский, Е. Д., & Polovinkina, V. V. (2021) · Obesity and metabolism · doi:10.14341/omet12750 · Cited by 8
Diwan, B., Yadav, R., Singh, A., Kumar, D., & Sharma, R. (2023) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-023-04193-4 · Cited by 8
Song, Y., Lei, H., Cao, Z., Zhang, C., Chen, C., Wu, M., Zhang, H., Du, R., Lijun, L., Chen, X., et al. (2024) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.4c00042 · Cited by 8
Bank, N. C., Singh, V., McCourt, B. T., Burberry, A., Roberts, K. D., Grubb, B. J., & Rodriguez‐Palacios, A. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2350150 · Cited by 10
Mcilwaine, C., Strachan, A., Harrington, Z., Jerreat, M. P., Belfield, L., Sándor, V., Foey, A., & Zarić, S. (2019) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2019.104633 · Cited by 8
Design of a Type-1 Diabetes Vaccine Candidate Using Edible Plants Expressing a Major Autoantigen
Bertini, E., Merlin, M., Gecchele, E., Puggia, A., Brozzetti, A., Commisso, M., Falorni, A., Bini, V., Klymyuk, V., Pezzotti, M., et al. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.00572 · Cited by 8
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Saadh, M. J., Ahmed, H. M., Alani, Z. K., Zuhairi, R. A. H. A., Almarhoon, Z. M., Ahmad, H., Ubaid, M., & Alwan, N. H. (2024) · NeuroMolecular Medicine · doi:10.1007/s12017-024-08783-4 · Cited by 8
Hansen, Z. A., Schilmiller, A. L., Guzior, D. V., Rudrik, J. T., Quinn, R. A., Vasco, K. A., & Manning, S. D. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1359576 · Cited by 7
Zhang, X., Chan, D., Zhu, J., Sin, D. Z. Y., Ye, P., Wong, M. K. L., Zhu, W., Tsui, Y., Haqq, A. M., Ting, J. Y., et al. (2025) · MedComm · doi:10.1002/mco2.70104 · Cited by 8
Zhang, Y., Zhu, Y., Li, M., Zhang, M., Shou, D., & Tong, P. (2025) · Nutrition and Diabetes · doi:10.1038/s41387-025-00374-x · Cited by 9
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Saadh, M. J., Mustafa, A. N., Mustafa, M. A., Renuka Jyothi, S., Dabis, H. K., Prasad, G. V. S., Mohammad, I. J., Adnan, A., & Idan, A. H. (2024) · Neurogenetics · doi:10.1007/s10048-024-00779-3 · Cited by 9
Wang, Z., Ojogun, N., Liu, Y., Gan, L., Xiao, Z., Feng, J., Jiang, W., Chen, Y., Zou, B., Yu, C., et al. (2025) · eLife · doi:10.7554/elife.100731.3 · Cited by 7
Htwe, P., Aung, H., Kywe, B., Niang, P. T., Oo, T. S., Monhandas, S., Kelly, L., & Goldman, D. L. (2021) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiab165 · Cited by 7
Noble, T. H., Samsing, F., Wade, N. M., Osborne, S. A., Addepalli, R., & Wynne, J. W. (2023) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2023.115626 · Cited by 7
Pennec, G. L., & Gardères, J. (2019) · Genes · doi:10.3390/genes10070485 · Cited by 7
Ketamine induced gut microbiota dysbiosis and barrier and hippocampal dysfunction in rats
Xie, L., Zhuang, Z., Guo, B., Huang, Y., Shi, X., Huang, Z., Xu, Z., Chen, Y., Cao, Y., Zheng, Y., et al. (2024) · iScience · doi:10.1016/j.isci.2024.111089 · Cited by 6
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Sarmikasoglou, E., Chu, L., Yue, F., & Faciola, A. P. (2023) · Journal of Dairy Science · doi:10.3168/jds.2023-23736 · Cited by 6
Zhang, L., Tan, J. T., Ng, H. Y., Liao, Y., Zhang, R., Chan, K., Hung, I. F., Lam, T. T., & Cheung, K. S. (2024) · Vaccines · doi:10.3390/vaccines12040365 · Cited by 7
Keener, J. E., Goh, B., Yoo, J., Oh, S. F., & Brodbelt, J. S. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c00952 · Cited by 6
Xie, S., Ying, Z., Xiu, Z., Sun, Y., Yang, Q., Gao, H., Fan, W., & Wu, Y. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1483680 · Cited by 6
Kusuma, R. J., Widada, J., Huriyati, E., & Julia, M. (2021) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2021.7540 · Cited by 6
García-Morena, D., Fernández-Cantos, M. V., Lopez-Escalera, S., Lok, J., Iannone, V., Cancellieri, P., Maathuis, W., Panagiotou, G., Aranzamendi, C., Aidy, S. E., et al. (2024) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-024-10219-1 · Cited by 6
Faraj, T. A., Edroos, G., & Erridge, C. (2024) · Food and Chemical Toxicology · doi:10.1016/j.fct.2024.114539 · Cited by 6
Sarmikasoglou, E., Vinyard, J. R., Khan, M. S., Jiranantasak, T., Ravelo, A. D., Lobo, R. R., Fan, P. F., Jeong, K. C., Tuanyok, A., & Faciola, A. P. (2021) · Polysaccharides · doi:10.3390/polysaccharides2040049 · Cited by 6
Vingeliene, S., Hiyoshi, A., Lentjes, M. A. H., Brummer, R. J., Fall, K., & Montgomery, S. (2024) · Brain Communications · doi:10.1093/braincomms/fcae098 · Cited by 5
Siddiqui, R., Lloyd, D., Maciver, S. K., & Khan, N. A. (2025) · Discover Medicine · doi:10.1007/s44337-025-00490-8 · Cited by 10
Lin, Z., Tang, H., Che, L., Chen, M., Ye, Z., Yang, X., Sun, L., Mayo, K. H., Tai, G., Cui, L., et al. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.124566 · Cited by 5
Patridge, E. V., Gorakshakar, A., Molusky, M. M., Ogundijo, O., Julian, C., Hu, L., Antoine, G., Vuyisich, M., Wohlman, R., & Banavar, G. S. (2025) · BMC Gastroenterology · doi:10.1186/s12876-025-04205-2 · Cited by 5
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Harvei, S., Skogen, V. H., Egelandsdal, B., Birkeland, S., Paulsen, J. E., & Carlsen, H. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1376493 · Cited by 6
Kuo, P., Rau, C., Wu, S., Lu, T., Wu, Y.-C., Chien, P., Wu, C., Lin, C.-W., Tsai, C.-W., Hsieh, C., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0220398 · Cited by 5
Johansen, V. B. I., Færø, D., Buschard, K., Kristiansen, K., Pociot, F., Kiilerich, P., Josefsen, K. E., Haupt‐Jorgensen, M., & Antvorskov, J. C. (2023) · Cells · doi:10.3390/cells12121567 · Cited by 5
Gan, L., Yu, C., Chen, J., Zou, B., Xiao, Z., Jiang, W., Li, D., Sun, Q., Wang, Z., Li, C., et al. (2025) · The FASEB Journal · doi:10.1096/fj.202500310r · Cited by 4
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Sazhin, A. V., Petukhov, V. A., Nechay, T. V., Ивахов, Г. Б., Stradymov, E. A., Akperov, A. I., & Rubtsov, A. A. (2021) · Novosti hirurgii · doi:10.18484/2305-0047.2021.2.221 · Cited by 4
Lin, S., Zhang, H., Wang, X., Lin, T., Chen, Z., Liu, J., & Wang, J. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.756976 · Cited by 4
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Baral, T., Kurian, S. J., Miraj, S. S., Munisamy, M., Kudru, C. U., Khandelwal, B., Banerjee, M., Mukhopadhyay, C., Saravu, K., Singh, J., et al. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822238-6.00036-4 · Cited by 4
Li, Y., Shi, J., Liu, Z., Lin, Y., Xie, A., Sun, W., Liu, J., & Liang, J. (2023) · Oncology Letters · doi:10.3892/ol.2023.14194 · Cited by 4
Zhu, Y., Pan, Y., Wang, X., Wei, L., Zhu, L., Yu, G., Jin, H., Gu, Y., Wang, Y., Chen, Y., et al. (2025) · Journal of Medicinal Food · doi:10.1089/jmf.2024.k.0184 · Cited by 3
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Rodrigues, T. V., de Jesus, L. C. L., Langella, P., Soares, S. D. C., Jan, G., Azevedo, V. A. D. C., & Chatel, J. (2026) · Annals of Medicine · doi:10.1080/07853890.2026.2618429 · Cited by 4
Gaber, M. K., Moulden, L. M., Wilson, A. S., Payne, V. S., Holmes, J., Neary, K., Peoples, A. E., Duet, M. L., Katz, A. J., Vidi, P., et al. (2026) · Neoplasia · doi:10.1016/j.neo.2026.101284 · Cited by 3
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Tanca, A., & Uzzau, S. (2025) · Expert Review of Proteomics · doi:10.1080/14789450.2025.2580644 · Cited by 4
Chałubiński, M., Wojdan, K., Łuczak, E., Gorzelak‐Pabiś, P., Kluszczyńska, K., Borowiec, M., Gajewski, A., Rudnicka, K., Chmiela, M., & Broncel, M. (2019) · Apmis · doi:10.1111/apm.12999 · Cited by 3
Laryushina, Y., Samoilova-Bedych, N., Turgunova, L., Marchenko, A., Turgunov, Y. M., Kozhakhmetov, S., Suieubayev, M., Mukhanbetzhanov, N., & Kabdulina, N. (2024) · Pathogens · doi:10.3390/pathogens14010005 · Cited by 4
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Pederson, J. W., & Nita‐Lazar, A. (2025) · mSystems · doi:10.1128/msystems.00185-25 · Cited by 2
Vargas-Caraveo, A., & Martı́nez-Martı́nez, A. (2025) · Medical Hypotheses · doi:10.1016/j.mehy.2025.111847 · Cited by 3
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Li, M., Chen, P., Liu, C., Wang, S., Zhang, H., Li, J., Karrow, N. A., Mao, Y., & Yang, Z. (2025) · Microorganisms · doi:10.3390/microorganisms13122829 · Cited by 2
Г.Т., Т., Zholdassova, M., Novosolova, N., Malm, T., Giniatullin, R. A., & Kustubayeva, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms27010369 · Cited by 4
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Daniels, N. C., Wilson, E. A. H., & Serbanescu, M. A. (2026) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000001399 · Cited by 2
Chen, L., Li, D., Shao, Y., Wang, H., Liu, Y., & Zhang, Y. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.01146 · Cited by 2
Khomich, M., Huang, L., Malinovschi, A., Brix, S., Cestelli, L., Peddada, S., Johannessen, A., Eriksen, C., Real, F. G., Svanes, C., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04199-z · Cited by 2
Eriksen, C., Danneskiold‐Samsøe, N. B., Moll, J. M., Myers, P. N., Bondegaard, P. W., Vejrum, S., Hansen, T. B., Rosholm, L. B., Rausch, P., Allin, K. H., et al. (2023) · Gut · doi:10.1136/gutjnl-2023-330677 · Cited by 3
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Yuan, M., Chen, H., & Rui, W. (2024) · Journal of Holistic Integrative Pharmacy · doi:10.1016/j.jhip.2024.09.004 · Cited by 2
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Haytoğlu, Z., Özcan, D., & Altıntaş, D. U. (2025) · Children · doi:10.3390/children12060734 · Cited by 8
Kitagawa, Y., Oishi, S., Koshimizu, K., Miura, R., Hamano, S., Iwata, H., & Shirasuna, K. (2025) · Animals · doi:10.3390/ani15182637 · Cited by 1
Abuqwider, J., Pasolli, E., Scidà, G., Corrado, A., Vitale, M., Filippis, F. D., Ercolini, D., Annuzzi, G., Rivellese, A. A., & Bozzetto, L. (2025) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2025.104487 · Cited by 1
Zhou, S., Gao, M., Dong, S., Wang, M., Xiao, H., Shu, Y., & Wang, X. (2025) · BMC Cancer · doi:10.1186/s12885-025-15387-z · Cited by 1
Liu, H., Yang, L., Huang, S., He, Y., Xie, Y., Jing, Y., Hu, B., Li, Z., Li, Z., & Li, Z. (2026) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-026-10952-9 · Cited by 1
Toh, J. Y. L., Tay, S. C., LIN, Z., Loo, E. X. L., Xu, J., Eriksson, J. G., Gluckman, P. D., Chong, Y. S., Meaney, M. E., Yap, F. S. D., et al. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2694805 · Cited by 1
Bacterial lipid structural diversity mediates commensalism and pathogenesis
Heaver, S. L., & Ley, R. E. (2026) · Nature Reviews Microbiology · doi:10.1038/s41579-026-01351-6 · Cited by 1
Neoadjuvant Vidutolimod and Nivolumab in High-Risk Resectable MelanomaPreprint
Davar, D., Morrison, R. M., Dzutsev, A., Karunamurthy, A., Chauvin, J.-M., Amatore, F., Stein, J. E., das Neves, R. X., Rodrigues, R. R., McCulloch, J. A., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2235839/v1 · Cited by 1
Ueda, M., Okahashi, N., & Arita, M. (2023) · Wiley eBooks · doi:10.1002/9783527836512.ch27 · Cited by 1
Proteases and Intestinal Health in Non-ruminants: A PerspectivePreprint
Broom, L. J. (2023) · Preprints.org · doi:10.20944/preprints202308.0761.v1 · Cited by 1
Wang, Z., Ojogun, N., Liu, Y., Gan, L., Xiao, Z., Feng, J., Jiang, W., Chen, Y., Zou, B., Yu, C., et al. (2024) · eLife · doi:10.7554/elife.100731.1 · Cited by 1
York, A. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.163
The Role of High Sugar Diets in Colitis
Rajaruban, S. (2020) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-tthe-t208
Investigating the effect of tetracycline on gut microbiome metabolism and microbe-host interactions
Keerthisinghe, R. P. T. P. (2021) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/152079
史新 (2007) · 广告导报
Wang, M. (2021) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/155796
Biddle, T. A., Yisrael, K., Drover, R. W., Li, Q., Maltz, M. R., Topacio, T. M., Yu, J., Castillo, D. D., Gonzales, D., Freund, H. L., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.07.506987
Large Association of GI Tract Microbial Community with Immune and Nervous Systems
Kazempour, A. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.104120 · Cited by 1
Endotoxin: Structure Source and Effects
Perrella, A., Carannante, N., Capoluongo, N., Mascolo, A., & Capuano, A. (2023) · Springer eBooks · doi:10.1007/978-3-031-18591-5_1
Johnson, S. D., Guda, R. S., Kumar, N., & Byrareddy, S. N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99744-7.00025-0
Additional file 3 of Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
Borgognone, A., Noguera-Julián, M., Oriol-Tordera, B., Noël‐Romas, L., Ruiz‐Riol, M., Guillén, Y., Parera, M., Casadellà, M., Duran-Castells, C., Puertas, M. C., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19581798
Metadata
- Authors
- d’Hennezel, E., Abubucker, S., Murphy, L. O., & Cullen, T. W.
- Affiliations
- Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research Inc., Cambridge, Massachusetts, USA
- Corresponding author
- Cullen, Thomas W.
- ORCID
- Abubucker, Sahar
- Venue
- mSystems
- Publisher
- American Society for Microbiology
- Published
- 2017-12-26
- Volume
- 2
- Issue
- 6
- ISSN
- 2379-5077 (ISSN-L)
- PMC
- PMC5686520
- OpenAlex
- W2770311021
- Cited by
- 324
- References
- 44
- Citations by year
- 2026: 21 · 2025: 32 · 2024: 43 · 2023: 43 · 2022: 49 · 2021: 62 · 2020: 37 · 2019: 27 · 2018: 8 · 2017: 1
- FWCI
- 9.03
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- mSystems (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Broad Institute
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Keywords
- gut microbiota, lipopolysaccharide, Toll-like receptor signaling, immune tolerance, host-microbe interactions, commensal bacteria, pro-inflammatory signaling, intestinal homeostasis, inflammatory diseases
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