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Improving the transition between paediatric and adult healthcare: a systematic review
Abstract
Introduction The transition between paediatric and adult care for young people with chronic illness or disability is often poorly managed, with adverse consequences for health. Although many agree that adolescent services need to be improved, there is little empirical data on which policies can be based. Objectives To systematically review the evidence of effectiveness of transitional care programmes in young people aged 11-25 with chronic illness (physical or mental) or disability, and identify their successful components. Design A systematic literature review in July 2010 of studies which consistently evaluated health outcomes following transition programmes, either by comparison with a control group or by measurement pre-intervention and post-intervention. Results 10 studies met the inclusion criteria, six of which showed statistically significant improvements in outcomes. Descriptive analysis identified three broad categories of intervention, directed at: the patient (educational programmes, skills training); staffing (named transition co-ordinators, joint clinics run by paediatric and adult physicians); and service delivery (separate young adult clinics, out of hours phone support, enhanced follow-up). The conditions involved varied (eg, cystic fibrosis, diabetes mellitus), and outcome measures varied accordingly. All six interventions that resulted in significant improvements were in studies of patients with diabetes mellitus, with glycosylated haemoglobin level, acute…
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“A systematic review of the literature on the transfer of care among different chronic diseases suggested that the most commonly used strategies in successful programmes were patient education and specific transition clinics jointly staffed by paediatric and adult physicians or dedicated young adult clinics within adult services (156).”
From ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease. (2022) · cites this paper as [156]
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La transition de la pédiatrie en médecine adulte : un défi à réussir
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“Although several transition models exist to facilitate transition by improving the emerging adult’s engagement with adult healthcare [5,13,14], risk assessment is also needed to identify who is most in need.”
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“Despite its importance, the transition from pediatric to adult care is often poorly planned or non-existent [15].”
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“31,32 Historically, many SMA patients have disengaged from services upon reaching adulthood due to fragmented care pathways through the transition period, as the application of therapies and evolution of disease management consensus has primarily focused on paediatric populations.”
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“Studies have demonstrated that multidisciplinary transition clinics, where paediatric and adult specialists collaborate, can signi fi cantly improve outcomes by providing consistent, coordinated care (23).”
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“Structured transition programs improve adjustment to adult life [151], especially for transplant recipients and high-risk HF patients, as younger transition age is associated with higher post-transplant mortality [152].”
Atzert, N., Gore, C., Knibb, R. C., Alviani, C., Angier, E., Blümchen, K., Comberiati, P., Duca, B., DunnGalvin, A., Garriga‐Baraut, T., et al. (2025) · Allergy · doi:10.1111/all.16603 · Cited by 2
Clinician perspectives on designing and implementing a hereditary cancer transition clinic
Gabriel, J. L., Schlieder, V., Goehringer, J., Leitzel, T., Sugrue, E. A., Zultevicz, S., Davis, T. W., Campbell‐Salome, G., & Romagnoli, K. M. (2025) · Hereditary Cancer in Clinical Practice · doi:10.1186/s13053-024-00304-5 · Cited by 2
“Many models of transition are reported in the literature, and there is no evidence that one is superior to another [20, 28, 52].”
Transition clinics in pediatric rheumatology in Colombia: reflection on a necessary shortcomings
Ramirez, L. N., Hoyos, M. E., Mosquera-Pongutá, A., & Quintana-López, G. (2025) · Advances in Rheumatology · doi:10.1186/s42358-024-00419-2 · Cited by 2
[History and challenges of the transition from pediatrics to adult care].
Morsa, M. (2023) · Soins Pédiatrie/Puériculture · doi:10.1016/j.spp.2023.10.003 · Cited by 2
Kikuchi, R., Sato, I., Hirata, Y., Sugiyama, M., Iwasaki, M., Sekiguchi, H., Sato, A., Suzuki, S., Morisaki-Nakamura, M., Kita, S., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289927 · Cited by 2
“Systematic reviews suggest that transition coordinators play an effective role in interventions for transition [48, 49].”
BackgroundProdam, F., Caputo, M., Romanisio, M., Brasili, S., Zavattaro, M., Samà, M. T., Ferrero, A., Costelli, S., Lenzi, F. R., Petri, A., et al. (2022) · Journal of Endocrinological Investigation · doi:10.1007/s40618-022-01975-4 · Cited by 6
“Thus, a structured transition plan is the emerging cornerstone, good for all patients, regardless diagnosis and comorbidities [2, 3].”
BackgroundBarriers, goals, and enablers of transition of care in pediatric dermatology
Pope, E. I., & Joseph, M. (2022) · Pediatric Dermatology · doi:10.1111/pde.15191 · Cited by 2
“, medication self-administration), ability to navigate the adult system, and autonomy.(22) However, these strategies must take into account individuals' developmental level and understanding, although can be delivered to families in cases where adolescents are unable to fulfill that role themselves.”
Background[Impact of the transition period from childhood to adulthood in cystic fibrosis].
Louagé, A., Knoop, C., & Hanssens, L. (2020) · Revue des maladies respiratoires · doi:10.1016/j.rmr.2019.11.650 · Cited by 2
Stephanie Bogue Kerr, M., Soulière, M., & Lorraine Bell, M. (2018) · The journal of nephrology social work · doi:10.61658/jnsw.v42i2.37 · Cited by 2
Visits to Pediatric Clinics by Adult Patients: A Nationwide Survey in Taiwan
Lee, K., Lynn, A., Chen, T.-J., Yang, L., & Chiang, S.-C. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15071538 · Cited by 2
Weiss, C., & Ammerman, S. D. (2016) · Journal of Child and Adolescent Behaviour · doi:10.4172/2375-4494.1000299 · Cited by 2
Transition of the patient with Juvenile Idiopathic Arthritis
Trachana, M. (2016) · doi:10.31138/mjr.27.2.63 · Cited by 2
Transition from paediatric to adult services in haemophilia
Chaplin, S. (2015) · doi:10.17225/jhp00059 · Cited by 2
‘The Lost Tribe’: a study of transition care in Lothian
Kyle, C. J., Patrick, A. W., & Zammitt, N. N. (2015) · The British Journal of Diabetes · doi:10.15277/bjdvd.2015.018 · Cited by 2
Majeed-Ariss, R., Hall, A., McDonagh, J., Fallon, D., & Swallow, V. (2015) · JMIR Research Protocols · doi:10.2196/resprot.4159 · Cited by 2
“This process of health transition as young people grow up requires them to develop clinical skills and knowledge in order to ultimately take responsibility for and competently manage their personal health where appropriate [2,8,9].”
Metadata
- Authors
- Crowley, R., Wolfe, I., Lock, K., & McKee, M.
- Affiliations
- London School of Hygiene & Tropical Medicine (GB)
- Corresponding author
- Wolfe, I
- Venue
- Archives of Disease in Childhood
- Publisher
- BMJ
- Published
- 2011-03-08
- Volume
- 96
- Issue
- 6
- Pages
- 548-553
- ISSN
- 0003-9888 (ISSN-L)
- 1468-2044
- OpenAlex
- W2121649468
- Cited by
- 649
- References
- 0
- Citations by year
- 2026: 29 · 2025: 27 · 2024: 25 · 2023: 33 · 2022: 45 · 2021: 44 · 2020: 49 · 2019: 54 · 2018: 43 · 2017: 57 · 2016: 53 · 2015: 56 · 2014: 47 · 2013: 44 · 2012: 32
- FWCI
- 7.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Disease in Childhood (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Adolescent and Pediatric Healthcare
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Child and Adolescent Health
- Health Sciences › Nursing › Leadership and Management › Hospital Admissions and Outcomes
- Keywords
- care transitions, chronic disease, disability, youth, diabetes mellitus, patient education, glycosylated haemoglobin, health outcomes
- MeSH terms
- Adolescent, Adult, Child, Chronic Disease, Continuity of Patient Care, Delivery of Health Care, Health Services Research, Humans, Patient Education as Topic, Adolescent Health Services, Outcome Assessment, Health Care, Young Adult
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