Aspetar clinical practice guideline on rehabilitation after anterior cruciate ligament reconstruction
Open accessAbstract
This guideline was developed to inform clinical practice on rehabilitation after anterior cruciate ligament reconstruction (ACLR) and was performed in accordance with the Appraisal of Guidelines for REsearch & Evaluation II (AGREE II) instrument and used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A Guideline Development Group systematically searched and reviewed evidence using randomised clinical trials and systematic reviews to evaluate the effectiveness of rehabilitation interventions and guide clinicians and patients on the content of the optimal rehabilitation protocol after ACLR.The guideline targets patients during rehabilitation after ACLR and investigates the effectiveness of the available interventions to the physiotherapist, alone or in combination (eg, exercise, modalities, objective progression criteria). Exercise interventions should be considered the mainstay of ACLR rehabilitation. However, there is little evidence on the dose-response relationship between volume and/or intensity of exercise and outcomes. Physical therapy modalities can be helpful as an adjunct in the early phase of rehabilitation when pain, swelling and limitations in range of motion are present. Adding modalities in the early phase may allow earlier pain-free commencement of exercise rehabilitation. Return to running and return to training/activity are key milestones for rehabilitation after ACLR. However, there is no evidence on which progression or discharge criteria should be used.While there is a very low level of certainty for most components of rehabilitation, most of the recommendations provided in this guideline were agreed to by expert clinicians. This guideline also highlights several new elements of ACLR management not reported previously.
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Gluteus maximus controls hip adduction and internal rotation, motions known to contribute to patellofemoral joint stress and PFP.
“During the acute phase, gluteus maximus activation should be emphasized as this muscle controls hip adduction and internal rotation, motions known to contribute to patellofemoral joint stress and PFP.43,44”
From A Biomechanical Review of the Squat Exercise: Implications for Clinical Practice. (2024) · cites this paper as [43]
The Results sections on Exercise initiation and Strength and motor control training discuss early quadriceps and hamstring strengthening, motor control, and anterior knee pain; page numbers were not available in our copy. Searches for gluteus maximus, hip adduction and internal rotation, and patellofemoral joint stress found no passage addressing the claimed mechanism or recommendation to emphasize gluteus maximus activation. (LLM, conf=0.74)
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Flagged first, then by citations
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Cited by
Sorted by citations
A Biomechanical Review of the Squat Exercise: Implications for Clinical Practice.
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Safran, E., & Yildirim, S. (2025) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-025-08650-8 · Cited by 21 · see citing works
- Authors
- Kotsifaki, R., Korakakis, V., King, E., Barbosa, O., Maree, D., Pantouveris, M., Bjerregaard, A., Luomajoki, J., Wilhelmsen, J., & Whiteley, R.
- Affiliations
- Qatar Orthopaedic and Sports Medicine Hospital (QA)
- ORCID
- Venue
- British Journal of Sports Medicine
- Publisher
- BMJ
- Published
- 2023-02-02
- Volume
- 57
- Issue
- 9
- Pages
- 500-514
- ISSN
- 0306-3674 (ISSN-L)
- 1473-0480
- PMC
- PMC11785408
- OpenAlex
- W4318972952
- Cited by
- 303
- References
- 175
- Citations by year
- 2026: 106 · 2025: 122 · 2024: 51 · 2023: 23
- FWCI
- 80.62
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- British Journal of Sports Medicine (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Aspetar Orthopaedic and Sports Medicine Hospital
- Topics
- Health Sciences › Medicine › Surgery › Knee injuries and reconstruction techniques
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports injuries and prevention
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
- Keywords
- anterior cruciate ligament reconstruction, rehabilitation, exercise therapy, physical therapy modalities, return to running, return to training, exercise dose-response, knee rehabilitation
- MeSH terms
- Anterior Cruciate Ligament Injuries, Exercise Therapy, Humans, Exercise, Physical Therapy Modalities, Anterior Cruciate Ligament Reconstruction
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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