Cited by 66Diabetes Management and ResearchElectrochemical sensors and biosensorsSpectroscopy Techniques in Biomedical and Chemical Research

In vivo glucose sensing for diabetes management: progress towards non-invasive monitoring

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Pickup, J., McCartney, L., Rolinski, O., Birch, D.·1999·BMJ

Abstract

A device for continuous in vivo monitoring of glucose concentration in people with diabetes has been a clinical and research priority for many years but now has an urgency which is probably unquestioned in diabetes care. The purpose of this article is to explain recent advances in technology that are bringing glucose sensors closer to routine use and to highlight some of the remaining problems. Important new technologies include artificial receptors for glucose, tissue fluid sampling techniques, and new approaches to non-invasive sensing, such as fluorescence lifetime measurements.

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Crossref · 10.1136/bmj.319.7220.1289

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  • Near-infrared spectroscopy allows 90-95% of light to pass through the stratum corneum and epidermis into subcutaneous space with minimal tissue adsorption independent of skin pigmentation.

    “Optical detection of glucose via near infrared (NIR) spectroscopy enables 90–95% of the light to pass through the human stratum corneum and epidermis into subcutaneous space with minimal tissue adsorption independent of skin pigmentation.19,40–41”

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Research works printed but not linked: 1

  1. Hashiguchi Y, Sakakida M, Nishida K, Uemura T, Kajiwara K-I, Shichiri M. Development of a miniaturised glucose monitoring system by combining a needle-type glucose sensor with microdialysis sampling method. Diabetes Care 1994;17:387-96.

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Authors
Pickup, J., McCartney, L., Rolinski, O., & Birch, D.
Affiliations
  • Guy's Hospital (GB)
  • University of Strathclyde (GB)
Corresponding author
Pickup, J.
Venue
BMJ
Publisher
BMJ
Published
1999-11-13
Volume
319
Issue
7220
Pages
1289-1289
ISSN
  • 0007-1447 (ISSN-L)
  • 0959-8138
  • 1468-5833
OpenAlex
W2055123658
Cited by
66
References
48
Citations by year
2026: 1 · 2024: 1 · 2018: 1 · 2016: 1 · 2014: 3 · 2013: 2 · 2012: 1
FWCI
2.53
Type
journal article
Language
en
Open access
Locations
  • BMJ (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Strathprints: The University of Strathclyde institutional repository (University of Strathclyde) (submittedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
Keywords
glucose detection, diabetes management, continuous glucose monitoring, non-invasive monitoring, fluorescence lifetime measurement
MeSH terms
Diabetes Mellitus, Type 1, Humans, Blood Glucose Self-Monitoring, Biosensing Techniques

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